维普中文期刊产品整合服务
229篇 您的检索式:作者名="Wu KK"
    题名 作者 年代 出处 被引量
1Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing显示文摘单个房间的定序是为描出的一个强大的工具为个性化的癌症管理的同种细胞的关系和识别关键司机基因。这里,我们执行了结肠癌的一个盒子的单个房间的定序的分析。人口遗传分析在肿瘤房间人口识别了二独立克隆。主要肿瘤克隆作为早 oncogenic 事件怀有 APC 和 TP53 变化,而次要的克隆包含了优势的 CDC27 和 PABPC1 变化。在这二克隆的次要的克隆支持的 APC 和 TP53 变化的缺席从二细胞的起源被导出。体的变化等位基因频率系列的检查另外 21 个整个织物的定序 exome 的盒子在结肠癌揭示了同种细胞的起源的异质。下次,我们识别了在单个房间的水平显示出变化的高频率,但是在人口水平展出了低流行的变异的基因 SLC12A5。变异的 SLC12A5 的功能的描述在结肠癌揭示了它的潜在的 oncogenic 效果。我们的学习在单个房间的水平支持提供第一条 exome 宽的证据那结肠癌能具有 biclonal 起源,并且建议在一个队的低流行的变化可以也在单个水平起重要 protumorigenic 作用。Chang Yu Jun Yu Xlaotlan Yao Wllham KK Wu Youyong Lu Senwel Tang Xiangchun Li Li Bao Xiaoxing Li Yong Hou Renhua Wu Min Jian Ruoyan Chen Fan Zhang Lixia Xu Fan Fan Jun He Qiaoyi Liang Hongyi Wang Xueda Hu Minghui He Xiang Zhang Hancheng Zheng Qibin Li Hanjie Wu Yan Chen Xu Yang Shida Zhu Xun Xu Huanming Yang Jian Wang Xiuqing Zhang Joseph JY Sung Yingrui Li Jun Wang 2014Cell Research2014,,6:16
2A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension显示文摘King Sum Luk Christina Ip Meng-Qi GONG Sunny Hei WONG William KK Wu Mei DONG Guang-Ping LI Ka Pang Chan Yi-Mei DU Tong LIU Martin CS Wong David Shu Cheong Hui Gary Tse 2017Journal of Geriatric Cardiology2017,14,12:5
3Platelet activation mechanisms and markers in arterial thrombosis显示文摘Wu KK 1996J Intern Med1996,239,:2
4The development of the Chinese version of impact of event scalerevised(CIES-R)显示文摘Wu KK Chan KS 2003Soc Psychiatry and Psychiatr Epidemiol2003,38,2:1
5Cigarette smoking and the risk of colorectal cancer: a meta-analysis of prospective cohort studies 显示文摘Tsoi KK Pan CY Wu WK 2009Clin Gastroenterol Hepatol2009,7,6:1
6Soluble thrombomodulin as predictor of incident coronary heart disease显示文摘 Wu KK 1999Lancet1999,354,:1
7Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease 显示文摘Wu KK Aleksic N Ahn C 2001Circulation2001,103,10:1
8Cigarette smoking and the risk of colorectal cancer : a recta-analysis of prospective cohort studies 显示文摘Tsoi KK Pau CY Wu WK 2009Clin Gastroenterol Hcpatol2009,7,6:1
9Tracking the intracellular path of poly (ethylenimine) DNA complexes for gene delivery 显示文摘Godbey WT Wu KK Mikos AG 1999Proc Natl Acad Sci USA1999,96,9:1
10Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery显示文摘Godbey WT Wu KK Mikos AG 1999Proc Natl Acad Sci USA1999,96,9:1
11Transcriptional induction of endothelial nitric oxide synthase type by lysophosphatidylcholine显示文摘Zembowicz A Tang J Wu KK 1995J Biol Chem1995,270,17:1
12Prospective study of hemostatic factors and incidence of coronary Communities study显示文摘Folsom AR Wu KK Rosanond MD 1997Circulation1997,96,:1
13Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery显示文摘 Wu KK Mikos AG 1999Proc Natl Acad Sci USA1999,96,9:1
14Association of coagulation factors and inhibitors with carotid artery atherosclerosis:Early results of the Atherosclerosis Risk in Communities (ARIC) Study 显示文摘Wu KK Folsom AR Heiss G 1992Ann Epidmiol1992,2,4:1
15Cigarette smoking and the risk of colorectal cancer: a meta-analysis of prospective cohort studies 显示文摘Tsoi KK Pau CY Wu WK 2009Clin Gastroenterol Hepatol2009,7,6:1
16High-resolution in vivo CBV mapping with MRI in wild-type mice显示文摘Wu EX Wong KK Andrassy M 2003Magn Reson Med2003,49,4:1
17Mapping cyclic change of regional myocardial blood volume using steady-state susceptibility effect of iron oxide nanoparticles 显示文摘Wu EX Tang H Wong KK 2004J Magn Reson Imaging2004,19,1:1
18Cyclopamine increases the radiosensitivity of human pancreatic cancer cells by regulating the DNA repair signal pathway through an epidermal growth factor receptor-dependent pathway显示文摘Wu XY Che J Sun KK 2013Mol Med Rep2013,8,4:1
19The development of the Chinese version of impact of event scale - revised (CIES-R) 显示文摘Wu KK Chan SK 2003Social Psychiatry and Psychiatric Epidemiology2003,38,2:1
20Endothelial prostaglandin and nitric oxide synthesis in atherosclerosis and thrombosis显示文摘Wu KK 1996J Formosan Med Assoc1996,95,9:1
返回顶部 每页显示:
共12页 首页 上一页 第1页 下一页 末页 /12 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费