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| 1 | The value of postoperative hepatic regional chemotherapy in prevention of recurrence after radical resection of primary liver cancer显示文摘INTRODUCTIONIn China,primary liver cancer (PLC) ranks secondin cancer mortality since the 1990s.In the field ofPLC treatment,surgical resection remains the best,which includes large PLC resection,small PLCresection,re-resection of subclinical recurrence,aswell as cytoreduction and sequential resection forunresectable PLC.However,recurrence | Wu ZQ Fan J Qiu SJ Zhou J Tang ZY | 2000 | World Journal of Gastroenterology2000，6，1： | 19 |
| 2 | Hepatocellular carcinoma HepG2 cell apoptosis and caspase-8 and Bcl-2 expression induced by injectable seed extract of Coix lacryma-jobi显示文摘BACKGROUND:Many Chinese herbs,especially herbal injections,have been shown to have anti-tumor effects in recent years.However,since most reports focus on the clinical effectiveness of these herbs,their mechanisms of action are not well understood.In this study,we assessed apoptosis in the hepatocellular carcinoma (HCC) cell line HepG2 induced by an injectable extract from the seed of Coix lacryma-jobi (Semen coicis,SC),and monitored the expression of Bcl-2 and caspase-8.METHODS:Injectable SC was applied to HepG2 cells at different concentrations and the cells were collected 12,24 and 48 hours later.5-fluorouracil was used as a positive control group,and fluorescence-activated cell-sorting cytometry was used to measure the apoptosis rate of HepG2 cells and the expression of Bcl-2 and caspase-8 proteins.RESULTS:SC induced apoptosis in HepG2 cells in a concentration and time-dependent manner,and the expression of caspase-8 was elevated and prolonged.However,it did not significantly influence the expression of Bcl-2.CONCLUSION:Injectable SC may induce apoptosis in HCC cells by regulating the expression of caspase-8. | Department of General Surgery (Lu Y and Zhang BY),Department of Bio-Information (Jia ZX),Affiliated Medical College Hospital,Qingdao University,Qingdao 266003,China Shanghai Jiaotong University School of Medicine,Shanghai 200025,China (Wu WJ) Department of Medicine,Heze Medical College,Heze 274000,China (Lu ZQ) | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 17 |
| 3 | Sirolimus-based immuno- suppression therapy in liver transplantation for patients with hepatocellular carcinoma exceeding the Milan crite- ria显示文摘 | Zhou J Wang Z Wu ZQ | 2008 | Transplant Proc2008，40，10： | 1 |
| 4 | Sirolimus-based immunosuppression therapy in liver transplantation for patients with hepatocellular eareinoma exceeding the Milan criteria 显示文摘 | Zhou J Wang Z Wu ZQ | 2008 | Transplant Proc2008，40，10： | 1 |
| 5 | Epidemiological and clinical studies on an outbreak of trichinosis in central China显示文摘 | Cui J Wang ZQ Wu F | 1997 | Ann Trop Med Parasitol1997，91，5： | 1 |
| 6 | Correlation between loneliness and social relationship among empty nest elderly in Anhui rural area,China显示文摘 | Wu ZQ Sun L Sun YH | 2010 | Aging Ment Health2010，14，1： | 1 |
| 7 | Sirolimus-based immunosuppression therapy in liver transplantation for patients with hepatocellular carcinoma exceeding the Milan criteria 显示文摘 | Zhou J Wang Z Wu ZQ | 2008 | Transplant Proc2008，40，10： | 1 |
| 8 | Loss of expression of miR-335 is implicated in hepatic stellate cell migration and activation 显示文摘 | Chen C Wu CQ Zhang ZQ | 2011 | Exp Cell Res2011，317，12： | 1 |
| 9 | Loss of expression of miR-335 is implicated in hepatic stellate cell migration and activation显示文摘 | Chen C Wu CQ Zhang ZQ | 2011 | Exp Cell Res2011，317，12： | 1 |
| 10 | Multimodality treatment in hepatocellular carcinoma patients with tumor thrombosis in portal vein显示文摘 | Fan J Wu ZQ | 2001 | World J Gastroen terol2001，7，1： | 1 |
| 11 | Structural analysis of selectedcharacteristic flavones by electrospray tandem mass spec-trometry显示文摘 | Wu W Liu ZQ Liu SY | 2004 | Analytical Sciences2004，20，7： | 1 |
| 12 | Antitumor activity of psoralen on mucoepidermoid carcinoma cell line MEC - 1 显示文摘 | Wu JZ Situ ZQ Wang W | 1992 | Chin Med J1992，105，： | 1 |
| 13 | Inhibition of MEK/ERK 1/2 pathway reduces pro-inflammatory cytokine interleukin-1 expression in focal cerebral ischemia显示文摘 | Wang ZQ Wu DC Huang FP | 2004 | Brain Res2004，996，： | 1 |
| 14 | Combinantion effects of γ-inter- feron with pinyanmycin or psoralen on tongue cancer HCS3 cell line in vitro and in vivio 显示文摘 | Wu JZ Situ ZQ Wang W | 1995 | Chinese Med J1995，108，4： | 1 |
| 15 | Epidemiological and clinical studies on an outbreak of trichinosis in central China显示文摘 | Cui J Wang ZQ Wu F | 1997 | Ann Trop Med Parasitol1997，91，5： | 1 |
| 16 | Calcimycin -induced lens epithelial cell aPoPtosis contributes to cataract formation 显示文摘 | LiWC Kuszak JR Wang GM Wu ZQ SPector A | 1995 | ExP Eye Tes1995，61，： | 1 |
| 17 | The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepati- tis is associated with regulating adiponectin receptor ex- pression in rats 显示文摘 | Liu S Wu HJ Zhang ZQ | 2011 | Eur J Pharmacol2011，650，： | 1 |
| 18 | Changes of expression of gial cell line - derived neurotrophic factor and its receptor in dosal root ganglions and spinal dorsal horn during electroacupuncture treatmentin neuropathic pain rats 显示文摘 | Dong ZQ Ma F Xie H Wang YQ Wu GC | 2005 | Neurosis Lett2005，1，1376： | 1 |
| 19 | Understanding ZHENG in tra- ditional Chinese medicine in the context of neuro-endocrine- immune network 显示文摘 | Li S Zhang ZQ Wu LJ etal | 2007 | IET Syst Biol2007，1，1： | 1 |
| 20 | Transducer of regulated CREB and late phase long-term synaptic potentiation显示文摘 | Wu H Zhou Y Xiong ZQ | 2007 | FEBS J2007，274，13： | 1 |
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