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| 1 | Counteraction of ABA-Mediated Inhibition of Seed Germination and Seedling Establishment by ABA Signaling Terminator in Arabidopsis显示文摘Seed germination and seedling establishment are important for the reproductive success of plants,but seeds and seedlings typically encounter constantly changing environmental conditions.By inhibiting seed germination and post-germinative growth through the PYR1/PYL/RCAR ABA receptors and PP2C co-receptors,the phytohormone abscisic acid(ABA)prevents premature germination and seedling growth under unfavorable conditions.However,little is known about how the ABA-mediated inhibition of seed germination and seedling establishment is thwarted.Here,we report that ABA Signaling Terminator(ABT),a WD40 protein,efficiently switches off ABA signaling and is critical for seed germination and seedling establishment.ABT is induced by ABA in a PYR1/PYL/RCAR-PP2C-dependent manner.Overexpression of ABT promotes seed germination and seedling greening in the presence of ABA,whereas knockout of ABT has the opposite effect.We found that ABT interacts with the PYR1/PYL/RCAR and PP2C proteins,interferes with the interaction between PYR1/PYL4 and ABI1/ABI2,and hampers the inhibition of ABI1/ABI2 by ABA-bound PYR1/PYL4,thereby terminating ABA signaling.Taken together,our results reveal a core mechanism of ABA signaling termination that is critical for seed germination and seedling establishment in Arabidopsis. | Zhijuan Wang Ziyin Ren Chunhong Cheng Tao Wang Hongtao Ji Yang Zhao Zhiping Deng Liya Zhi Jingjing Lu Xinying Wu Shimin Xu Mengmeng Cao Hongtao Zhao Liu Liu Jiankang Zhu Xia Li | 2020 | Molecular Plant2020，13，9： | 10 |
| 2 | Performance study of a water ramjet engine显示文摘A performance study of a water ramjet engine is described.The engine is powered by the reaction of a magnesium-based propellant and ingested water.In this study,a solid propellant,which consisted of a large percentage of magnesium,a binder and a small amount of oxidant,was used as a hydro reactive fuel.Cold water was injected into the combustion chamber as a main oxidant.A scaled-down experimental engine was tested in a direct-connect ground testing system to characterize the factors influencing the engine performance.The results show that the increasing of total water/fuel ratio,an addition of secondary water intake along the combustion chamber,a larger magnesium content in the solid propellant,a smaller primary water injection angle towards the coming main flow,and a higher primary injection pressure were all able to promote the engine performance.The maximum engine performance was obtained in test 08,and with all tests,an appropriate set of parameters and conditions for the optimum engine performance were | HUANG LiYa XIA ZhiXun HU JianXin ZHU QianWen | 2011 | Science China(Technological Sciences)2011，54，4： | 5 |
| 3 | 2022 Chinese national clinical practice guideline on Helicobacter pylori eradication treatment显示文摘Background:Helicobacter pylori(H.pylori)infection is an infectious disease with a prevalence rate of up to 50%worldwide.It can cause indigestion,gastritis,peptic ulcer,and gastric cancer.H.pylori eradication treatment can effectively control disease progression and reduce the risk of the above conditions.However,the escalating trend of antibiotic resistance presents a global challenge for H.pylori eradication.We aim to provide guidance on pharmacological treatment of H.pylori infection.Methods:This clinical practice guideline is developed following the World Health Organization’s recommended process,adopting Grading of Recommendations Assessment,Development and Evaluation in assessing evidence quality,and utilizing Evidence to Decision framework to formulate clinical recommendations,minimizing bias and increasing transparency of the clinical practice guideline development process.We used the Reporting Items for practice Guidelines in HealThcare(RIGHT)statement and The Appraisal of Guidelines for Research and Evaluation Ⅱ(AGREE Ⅱ)as reporting and conduct guides to ensure the guideline’s completeness and transparency.Results:Though decreasing in developed countries,the prevalence of H.pylori remains high in developing countries,causing a major public health burden.This clinical practice guideline contains 12 recommendations concerning pharmacological treatment for H.pylori eradication.Among them,it is worth highlighting that bismuth preparations are inexpensive,safe,and effective,consequently making bismuth quadruple therapy a preferred choice for initial and rescue treatment.In empirical treatment,high-dose dual therapy is equally effective compared with bismuth quadruple therapy.Conclusions:The 12 recommendations in this clinical practice guideline are formed with consideration for stakeholders’values and preferences,resource use,feasibility,and acceptability.Recommendations are generalizable to resource limited settings with similar antibiotic resistance pattern as China,and lower middle-income countries facing comparable sociological and technical challenges.Registration:Guidelines International Network(GIN)website,http://gffzz8d0dcdd112684267svwwnqv6pwuu56fxn.ffgz.tsg.suse.edu.cn/node/69996. | Liya Zhou Hong Lu Zhiqiang Song Bin Lyu Ye Chen Jiyao Wang Jun Xia Zhan Zhao on behalf of Helicobacter Pylori Study Group of Chinese Society of Gastroenterology | 2022 | Chinese Medical Journal2022，135，24： | 5 |
| 4 | Experimental study on the ignition and combustion characteristics of a magnesium particle in water vapor显示文摘Magnesium is of interest for underwater propulsion due to the superior ignition behavior of magnesium particles and the highly exothermic Mg-water reaction.In this work,the ignition and combustion characteristics of an individual millimeter-sized magnesium particle in water vapor were studied.In order to build an atmosphere of water vapor,an experiment system was established and validated by the experiments of magnesium particle in air.The ignition and combustion of a single magnesium particle were accomplished in a combustor filled with water vapor.The surface changes of the particle during the ignition and a steady-state vapor phase combustion were observed.Based on the data obtained,ignition mechanism was analyzed and ignition temperature was determined.The steady-state combustion of the sample was controlled by diffusion in gas phase,and a one-dimensional,spherically symmetric quasi-steady model was adopted to describe the process.The dependence of burning time on the diameter was investigated,and the conclusion that burning time is proportional to the square of the metal sample diameter was drawn. | HUANG Xu XIA ZhiXun HUANG LiYa HU JianXin | 2012 | Science China(Technological Sciences)2012，55，9： | 1 |
| 5 | Structure of a bo- ron-containing bisphenol-F formaldehyde resin and kinetics of its thermal degradation显示文摘 | GAO Junguang XIA Liya LIU Yanfang | 2004 | Polymer Degradation and Stabili- ty2004，83，1： | 1 |
| 6 | Ilaprazole for the treatment of duodenal ulcer: a randomized, double-blind and controlled phase III trial显示文摘 | Ling Wang Liya Zhou Haitang Hu Sanren Lin Jielai Xia | 2012 | Current Medical Research & Opinion2012，，1： | 1 |
| 7 | A New PPI, Ilaprazole Compared With Omeprazole in the Treatment of Duodenal Ulcer: A Randomized Double-Blind Multicenter Trial显示文摘 | Ling Wang Liya Zhou Sanren Lin Haitang Hu Jielai Xia | 2011 | Journal of Clinical Gastroenterology2011，，4： | 1 |
| 8 | Experimental investigation of supersonic flow over a hemisphere显示文摘The experimental investigation of supersonic flow over a hemisphere was conducted using Nanoparticle-based Planar Laser Scattering(NPLS) technique in a supersonic quiet wind tunnel at Ma=2.68.Ahead of the hemisphere,boundary layer separation with the formation of a three-dimensional separated flow was observed,which was resulted from the interaction between the three-dimensional bow shock wave and the boundary layer.The complex flow structures of supersonic flow over the hemisphere were visualized.Based on the time correlation of NPLS images,time-space evolutionary characteristics of supersonic flow over the hemisphere were studied,and the evolutionary characteristics of the spanwise and streamwise large scale vortex structures were obtained,which have the features of periodicity and similar geometry. | WANG DengPan ZHAO YuXin XIA ZhiXun WANG QingHua HUANG LiYa | 2012 | Chinese Science Bulletin2012，57，15： | 1 |
| 9 | Biocompatibility of Fe3O4/DNR magnetic nanoparticles in the treatment of hematologic malignancies显示文摘 | Baoan Chen Feng Gao Jing Chen Jun Wang Wei Hulai Jian Cheng Xia Guohua Baoan Chen Liu Lijie Chuanlu Xu Wu Weiwei Bao wen Zhang Yi Ding Jiahua Yang Liya Shen Huiling Yang Mimgming Xu Wenlin Xuemei Wang | 2010 | 2010 (defa)2010，，： | 1 |
| 10 | Determination of the geographic origin of rice by element fingerprints and correlation analyses with the origin soil 显示文摘 | ShigangShen Liya Xia Na Xiong Hanwen Sun | 2013 | AnalyticalMethods2013，5，21： | 1 |
| 11 | Synthesis and structure characterization of boron-nitrogen containing phenol formal- dehyde resin 显示文摘 | Gao Jungang Su Xiaohui Xia Liya | 2005 | Int J Polym Mater Polym Biomater2005，54，： | 1 |
| 12 | 脑启发的人工智能综述:进展与应用显示文摘Recent advances in Artificial Intelligence(AI)have indicated that inspirations from the brain can effectively improve the level of intelligence for AI computational models,even if just local and partial inspirations.Nevertheless,realizing and exceeding intelligence at a human level still needs a deeper investigation and inspirations from the brain.The goal of brain-inspired intelligence is to achieve human intelligence inspired from brain neural mechanism and cognitive behavior mechanism.To this end,in this paper we introduce the relationship between AI and neuroscience,the current status of brain-inspired intelligence,the future work in intelligent control systems,and its profound influence in other fields. | IA Tianyuan FAN Chaoqiong WANG Lina WANG Liya WU Xia | 2021 | Aerospace China2021，22，1： | 0 |
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