|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of Liuweibuqi capsule, a Chinese patent medicine, on the JAK1/STAT3 pathway and MMP9/TIMP1 in a chronic obstructive pulmonary disease rat model显示文摘OBJECTIVE: To observe effect of Liuweibuqi Capsule, a Traditional Chinese Medicine(TCM), on the janus kinase(JAK)/signal transducer and activator of transcription(STAT) pathway and matrix metalloproteinases(MMPs) in a chronic obstructive pulmonary disease(COPD) rat model with lung deficiency in terms of TCM's pattern differentiation.METHODS: Rats were randomly divided into a normal group, model group, Liuweibuqi group, Jinshuibao group, and spleen aminopeptidase group(n=10). Aside from the normal group, all rats were ex-posed to smoke plus lipopolysaccharide tracheal instillation to establish the COPD model with lung deficiency. Models were established after 28 days and then the normal and model groups were given normal saline(0.09 g/kg), Liuweibuqi group was given Liuweibuqi capsule(0.35 g/kg), Jinshuibao group was given Jinshuibao capsules(0.495 g/kg), and the spleen group was given spleen aminopeptidase(0.33 mg/kg), once a day for 30 days. Changes in symptoms, signs, and lung histology were observed. Lung function was measured with a spirometer. Serum cytokines were detected using enzyme-linked immunosorbent assay, and changes in the JAK/STAT pathway, MMP-9, and MMPs inhibitor1(TIMP1) were detected by immunohistochemistry, RT-PCR, and western blotting, respectively.RESULTS: Compared with the normal group, lung tissue was damaged, and lung function was reduced in the model control group. Additionally, the levels of interleukin(IL)-1β, γ interferon(IFN-γ), and IL-6 were higher, while IL-4 and IL-10 were lower in the model control group than those in the normal group. The expressions of JAK1, STAT3, p-STAT3,and MMP-9 m RNA and protein in lung tissue were higher, and TIMP1 m RNA and protein was lower in the model group compared with the normal group.After treatment, compared with the model group,the expression of inflammatory cytokines was lower in each treatment group, and expressions of JAK/STAT pathway, MMPs were lower. Compared with the positive control groups, the Jinshuibao and spleen aminopeptidase groups, lung function was better, and JAK1, STAT3, and p-STAT3 protein were lower and TIMP1 was higher in the Liuweibuqi group.CONCLUSION: Liuweibuqi capsules can improve the symptoms of COPD possibly by regulating the expression of the JAK1/STAT3 pathway and MMP9/TIMP1. | Wang Chengyang Li Zegen Liu Xiangguo Peng Qinghe Li Fang Li Da Wang Chuanbo | 2015 | Journal of Traditional Chinese Medicine2015，35，1： | 23 |
| 2 | Analysis and Numerical Simulation of Rolling Contact between Sphere and Cone显示文摘In non-conforming rolling contact, the contact stress is highly concentrated in the contact area. However, there are some limitations of the special contact model and stress model used for the theoretical study of the phenomenon, and this has prevented in-depth analysis of the associated friction, wear, and failure. This paper is particularly aimed at investigating the area of rolling contact between a sphere and a cone, for which purpose the boundary is determined by the Hertz theory and the geometries of the non-conforming surfaces. The phenomenon of stick-slip contact is observed to occur in the contact area under the condition of no-full-slip(Q < μ·P). Using the two-dimensional rolling contact theory developed by CARTER, the relative positions of the stick and slip regions and the distribution of the tangential force over the contact area are analyzed. Furthermore, each stress component is calculated based on the Mc Ewen theory and the idea of narrow band. The stress equations for the three-dimensional rolling contact between the sphere and the cone are obtained by the principle of superposition, and are used to perform some numerical simulations. The results show that the stress components have a large gradient along the boundary between the stick and slip regions, and that the maximum stress is inversely proportional to the contact coefficient and proportional to the friction coefficient. A new method for investigating the stress during non-classical three-dimensional rolling contact is proposed as a theoretical foundation for the analysis of the associated friction, wear, and failure. | ZHAO Yanling XIA Chengtao WANG Hongbo XUAN Jiaping XIANG Jingzhong LIU Xianli SU Xiangguo | 2015 | Chinese Journal of Mechanical Engineering2015，28，3： | 18 |
| 3 | ZmCOL3, a CCT gene represses flowering in maize by interfering with the circadian clock and activating expression of ZmCCT显示文摘Flowering time is a trait vital to the adaptation of flowering plants to different environments.Here, we report that CCT domain genes play an important role in flowering in maize(Zea mays L.).Among the 53 CCT family genes we identified in maize, 28 were located in flowering time quantitative trait locus regions and 15 were significantly associated with flowering time, based on candidate-gene association mapping analysis.Furthermore, a CCT gene named ZmCOL3 was shown to be a repressor of flowering.Overexpressing ZmCOL3 delayed flowering time by approximately 4 d, in either long-day or short-day conditions.The absence of one cytosine in the ZmCOL3 3'UTR and the presence of a 551 bp fragment in the promoter region are likely the causal polymorphisms contributing to the maize adaptation from tropical to temperate regions.We propose a modified model of the maize photoperiod pathway, wherein ZmCOL3 acts as an inhibitor of flowering either by transactivating transcription of ZmCCT, one of the key genes regulating maize flowering, or by interfering with the circadian clock. | Minliang Jin Xiangguo Liu Wei Jia Haijun Liu Wenqiang Li Yong Peng Yanfang Du Yuebin Wang Yuejia Yin Xuehai Zhang Qing Liu Min Deng Nan Li Xiyan Cui Dongyun Hao Jianbing Yan | 2018 | Journal of Integrative Plant Biology2018，60，6： | 14 |
| 4 | Effect of Wuziyanzong Pill on sperm quality and calcium ion content in oligoasthenospermia rats显示文摘OBJECTIVE:To study the effect of Wuziyanzong treatment on the sperm quality and content of calcium ions(Ca 2+) in oligoasthenospermia rats.METHODS:A model of oligoasthenospermia was induced in 50 Sprague Dawley rats by treatment with tripterygium glycosides at 30 mg/kg per day for 8 weeks.They were divided randomly into a model group,a positive group(Huangjingzanyu capsule,3.01 g/kg),and low,medium and high dose Wuziyanzong treatment groups(2.30,4.60,9.20 g/kg crude drug respectively) with 10 in each group.Another 10 rats were used as a control group.The rats in the control and model groups were administered distilled water,while the rats in the remaining groups were administered Wuziyanzong for 30 d.The epididymides were removed,spermatozoa recovered and the sperm density and viability were measured.The spermatozoa were purified and the contents of Ca 2+ in the cytoplasm and mitochondria were detected by flow cytometry and atomic absorption spectrometry,respectively.RESULTS:After 8 weeks of treatment with tripterygium glycosides,the sperm density,sperm activity and the Ca 2 + content of spermatozoa in the model rats were all significantly decreased compared with the control group(all P<0.05).After 30 d treatment,the sperm density and activity improved and the Ca 2 + content of sperm were increased significantly in the medium and high dose Wuziyanzong treatment groups in comparison with the model group(all P<0.05).CONCLUSION:The Wuziyanzong treatment increased sperm density,improved sperm viability and enhanced the content of Ca 2+ in the sperm cytoplasm and mitochondria in this rat model of oligoasthenospermia. | Tongsheng Wang Jinling Huang Deling Wu Qing Li Xiangguo Liu Han Chen Lei Qiao Dongdong Li Jun Li | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 11 |
| 5 | IDENTITY-BASED MULTISIGNATURE AND AGGREGATE SIGNATURE SCHEMES FROM M-TORSION GROUPS显示文摘An identity-based multisignature scheme and an identity-based aggregate signature scheme are proposed in this paper. They are both from m-torsion groups on super-singular elliptic curves or hyper-elliptic curves and based on the recently proposed identity-based signature scheme of Cha and Cheon. Due to the sound properties of m-torsion groups and the base scheme, it turns out that our schemes are very simple and efficient. Both schemes are proven to be secure against adaptive chosen message attack in the random oracle model under the normal security notions with the assumption that the Computational Diffie-Hellman problem is hard in the m-torsion groups. | Cheng Xiangguo Liu Jingmei Guo Lifeng Wang Xinmei | 2006 | Journal of Electronics(China)2006，23，4： | 11 |
| 6 | Study of action mechanisms and properties of Cr^(3+) cross-linked polymer solution with high salinity显示文摘Performance characteristics of partially hydrolyzed polyacrylamide (HPAM) and cross-linked polymer (CLP, Cr 3+ as the cross linker) solutions have been investigated. A Brookfield viscometer, rheometer, dynamic light scattering system, and core flow device have been used to measure the viscosity, viscoelasticity, polymer coil dimensions, molecular configuration, flow characteristics, and profile modification. The results show that, under conditions of high salinity and low HPAM and Cr 3+ concentrations, cross-linking mainly occurred between different chains of the same HPAM molecule in the presence of Cr 3+ , and a cross-linked polymer (CLP) system with a local network structure was formed. Compared with an HPAM solution of the same concentration, the apparent viscosity of the CLP solution increased slightly or remained almost unchanged, but its viscoelasticity (namely storage modulus, loss modulus, and first normal stress difference) increased, and the resistance coefficient and residual resistance coefficient increased significantly. This indicates that the CLP solution exhibits a strong capability to divert the sequentially injected polymer flood from high-permeability zones to low-permeability zones in a reservoir. Under the same HPAM concentration conditions, the dimensions of polymer coils in the CLP solution increased slightly compared with the dimensions of polymer coils in HPAM solution, which were smaller than the rock pores, indicating that the cross-linked polymer solution was well adapted to reservoir rocks. Core flood experiments show that at the same cost of reagent, the oil recovery by CLP injection (HPAM-1, Cr 3+ as the cross linker) is 3.1% to 5.2% higher than that by HPAM- 2 injection. | Lu Xiangguo Liu Jinxiang Wang Rongjian Liu Yigang Zhang Song | 2012 | Petroleum Science2012，9，1： | 8 |
| 7 | A THRESHOLD BLIND SIGNATURE FROM WEIL PAIRING ON ELLIPTIC CURVES显示文摘The idea behind a (t, n) threshold blind signature is that a user can ask at least t out of n players of a group to cooperate to generate a signature for a message without revealing its content. This paper first presents a new blind signature scheme from Weil pairing on elliptic curves. Based on this scheme, a threshold blind signature scheme is proposed. It is efficient and has the security properties of robustness and unforgeability. In the proposed scheme, the group manger is introduced to take the role of distributing the group secret key to each player. However, he cannot forge the players to generate partial blind signatures (Each partial blind signature depends on not only the secret key of the player, but also a random number the player picks). Compared with a threshold signature with a trusted third party, its advantage is obvious; Compared with a threshold signature without a trusted third party, it is more simple and efficient. | Cheng Xiangguo Xu Weidong Wang Xinmei | 2006 | Journal of Electronics(China)2006，23，1： | 6 |
| 8 | Coal mining GPS subsidence monitoring technology and its application显示文摘We proved theoretically that geodetic height,measured with Global Positioning System(GPS),can be applied directly to monitor coal mine subsidence.Based on a Support Vector Machine(SVM) model,we built a regional geoid model with a Gaussian Radial Basis Function(RBF) and the technical scheme for GPS coal mine subsidence monitoring is presented to provide subsidence information for updating the regional Digital Elevation Model(DEM).The theory proposed was applied to monitor mining subsidence in an Inner Mongolia coal mine in China.The scheme established an accurate GPS reference network and a comprehensive leveling conjunction provided the normal height of all GPS control points.According to the case study,the SVM model to establish geoid-model is better than a polynomial it or a Genetic Algorithm based Back Propagation(GA-BP) neural network.GPS-RTK measurements of coal mine subsidence information can be quickly acquired for updating the DEM. | Wang Jian Peng Xiangguo Xu Chang hui | 2011 | Mining Science and Technology2011，21，4： | 6 |
| 9 | Performance evaluation of oil displacing agents for primary-minor layers of the Daqing Oilfield显示文摘一系列实验被进行调查分子的卷尺寸(D h ) 和分子的配置部分 hydrolyzed polyacrylamides (HPAM ) , surfactant/HPAM 系统,和生活聚合物。在聚合物卷和多孔的媒介之间的相容性被仪器的分析和实验室模拟方法评估。同时,化学泛滥的表演被调查。结果显示 D h 随水咸度的增加减少了并且随聚合物集中的增加增加了。在水的答案,聚合物介绍了三维的网状的配置并且展出了自我类似描绘的分数维的结构。在 surfactant/HPAM 系统的聚合物主要在表面活化剂聚合物建筑群化合物形式,生活聚合物有导致了在分子的卷和多孔的媒介之间的相对差的相容性的一种不规则的片状网状的配置。代替代理人和它的蛞蝓尺寸的油的类型影响了增长的油恢复。为代替代理人的一样的油,一种更大的蛞蝓尺寸将导致更好化学的泛滥回答。给最后的恢复效率和经济好处,高强度聚合物泛滥作为提高的 optimimal 被选择油恢复(EOR ) 技术和增长恢复效率是预报是 20% 。 | Zhang Jian Wang Shuxia Lu Xiangguo He Xianhua | 2011 | Petroleum Science2011，8，1： | 5 |
| 10 | Elastic Scattering of 7Be on Pb Target显示文摘 | Yang Yanyun Wang Jiansong Wang Qi Huang Meirong Ma Junbing Ma Peng Cao Xiguang Han Jianlong Bai Zhen Jin Shilong Hu Qiang Jin Lei Chen Jiangbo Zhang Xueying Chen Ruofu Hu Zhengguo Xu Shiwei Zhen Chuan Xu Zhiguo Xu Hushan Duan Liming Sun Zhiyu Chen Zhiqiang He Jianjun Li Songlin Lei Xiangguo Fu Fen Zhang Xueheng Yuan Xiaohua Du Chengming Yan Xinshuang Hu Jun Tang Shuwen Ye Ruiping Yang Kun Shi Fudong Zhang Wei Chen Ze Li Long Xu Xing Liu Longxiang Zhang Liyong Lin Qingyun Gou Boxing Xu Ge Zhou Xionghong Zhang Yuhu Xiao Guoqing | 2011 | IMP & HIRFL Annual Report2011，，1： | 4 |
| 11 | Enhanced oil recovery mechanisms of polymer flooding in a heterogeneous oil reservoir显示文摘Taking reservoir rocks and fluids of the Daqing,Dagang and Changqing oilfields as research objects,the EOR mechanisms and technical approach of polymer flooding were discussed.By comparing the displacement performances of ordinary polymer,glycerol,polymer in'sheet-net'structure and heterogeneous weak gel at the same viscosity and concentration,the relationship between the viscosity of polymer displacement agents and displacement performance was demonstrated,and the method of improving polymer flooding effect was worked out.The main mechanism of polymer flooding to increase oil recovery is the swept volume expansion of water injection due to polymer retention in porous media.The viscosity of polymer agents has no positive correlation with polymer flooding effect.Although polymer of'sheet-net'structure has strong capacity in increasing viscosity,it has poor compatibility with pore throat structure of reservoir rock,low injectivity and low shear resistance.Heterogeneous weak gel system has higher adsorption and capture capacity in porous media,which is easy to retain in porous media,and can effectively establish seepage resistance in high permeability layers(zones).Compared with polymer solutions with the same viscosity or concentration,it has stronger ability to expand swept volume.Long term injection of polymer flooding agents will inevitably lead to fluid entry profile reversal,and thus worsening of polymer flooding effect.Alternate injection of high retention and low or non-retention displacement agents can further improve the displacement effect of polymer flooding agents. | LU Xiangguo CAO Bao XIE Kun CAO Weijia LIU Yigang ZHANG Yunbao WANG Xiaoyan ZHANG Jie | 2021 | Petroleum Exploration and Development2021，48，1： | 4 |
| 12 | Correlation between microstructures and mechanical properties of high-speed friction stir welded aluminum hollow extrusions subjected to axial forces显示文摘The AA6005A-T6 aluminum hollow extrusions were friction stir welded at a high welding speed of 2000 mm/min and various axial forces. The results show that the nugget zone(NZ) is characterized by fine equiaxed grains, in which a low density of equilibrium phase is observed. The grains in the thermo-mechanically affected zone(TMAZ) are elongated, and the highest density of dislocations and a low density of ' precipitates can be found in grains. The heat affected zone(HAZ) only experiences a low thermal cycle, and a high density of ' precipitates and a low density of ' precipitates remain in the coarsened grains. The microhardness evolutions in the NZ, TMAZ and HAZ are governed by the grain refinement and dislocation strengthening, the dislocation and precipitation strengthening, and the precipitation and solid solution strengthening, respectively. When increasing the axial force, the changing trend of one strengthening mechanism is contrary to the other in each zone, and the microhardness increases in different zones. As a result, the tensile strength roughly increases with raising the axial force, and all joints show good tensile properties as the high welding speed inhibits the coarsening and dissolution of strengthening precipitates significantly. | Xiangqian Liu Huijie Liu Tianhao Wang Xiangguo Wang Si Yang | 2018 | Journal of Materials Science & Technology2018，34，1： | 3 |
| 13 | Confining TiO_2 Nanotubes in PECVD-Enabled Graphene Capsules Toward Ultrafast K-Ion Storage: In Situ TEM/XRD Study and DFT Analysis显示文摘Titanium dioxide(TiO2) has gained burgeoning attention for potassium-ion storage because of its large theoretical capacity,wide availability,and environmental benignity.Nevertheless,the inherently poor conductivity gives rise to its sluggish reaction kinetics and inferior rate capability.Here,we report the direct graphene growth over TiO2 nanotubes by virtue of chemical vapor deposition.Such conformal graphene coatings effectively enhance the conductive environment and well accommodate the volume change of TiO2 upon potassiation/depotassiation.When paired with an activated carbon cathode,the graphene-armored TiO2 nanotubes allow the potassium-ion hybrid capacitor full cells to harvest an energy/power density of 81.2 Wh kg-1/3746.6 W kg-1.We further employ in situ transmis sion electron microscopy and ope rando X-ray diffraction to probe the potassium-ion storage behavior.This work offers a viable and versatile solution to the anode design and in situ probing of potassium storage technologies that is readily promising for practical applications. | Jingsheng Cai Ran Cai Zhongti Sun Xiangguo Wang Nan Wei Feng Xu Yuanlong Shao Peng Gao Shixue Dou Jingyu Sun | 2020 | Nano-Micro Letters2020，12，9： | 2 |
| 14 | Identification of Oblate Band in Odd-odd ^(184)Au显示文摘The high-spin states in 184Au were populated by using the 159Tb( 29Si, 4ng) 184Au reaction at a bombarding energy of 140 MeV. The 29Si beam of 8 pnA was provided by the accelerator complex of the Tandem-XTU and ALPI at the Laroratori Nazionale di Legnero, Italy, and focussed onto a natural metallic 159Tb foil | Zhang Yuhu Wang Hualei G. de Angelis N. Maiginean A. Gadea D. R. Napoli M. Axiotis C. R.usu T. Martinez Zhou Xiaohong Fang Yongde Guo Wentao Liu Minliang Lei Xiangguo Guo Yingxiang | 2004 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2004，，1： | 2 |
| 15 | PREDICTIVE APPROACH TO FAILURE OF COMPOSITE LAMINATES WITH EQUIVALENT CONSTRAINT MODEL显示文摘This work established a new analytical model based upon the equivalent constraint model(ECM)to constitute an available predictive approach for analyzing the ultimate strength and simulating the stress/strain response of general symmetric laminates subjected to combined loading,by taking into account the effect of matrix cracking.The ECM was adopted to mainly predict the in-plane stiffness reduction of the damaged laminate.Basic consideration that progressive matrix cracking provokes a re-distribution of the stress fields on each lamina within laminates, which greatly deteriorates the stress distributed in the primary load-bearing lamina and leads to the final failure of the laminates,is introduced for the construction of the failure criterion. The effects of lamina properties,lay-up configurations and loading conditions on the behaviors of the laminates were examined in this paper.A comparison of numerical results obtained from the established model and other existed models and published experimental data was presented for different material systems.The theory predictions demonstrated great match with the experimental observations investigated in this study. | Fang Wang Xiangguo Zeng Junqian Zhang | 2010 | Acta Mechanica Solida Sinica2010，23，3： | 2 |
| 16 | Natural astaxanthin enhanced antioxidant capacity and improved semen quality through the MAPK/Nrf2 pathway in aging layer breeder roosters显示文摘Background:Natural astaxanthin(ASTA)has strong antioxidant properties and has been widely used as a health product to improve human health.However,the effects of ASTA on the reproductive performance of aging roosters have been poorly studied.We aimed to investigate the effects of dietary ASTA on semen quality and antioxidant capacity in aging roosters and to explore the potential mechanism of semen quality change via antioxidation defense system.Methods:In the present study,9653-week-old Jinghong No.1 layer breeder roosters were fed a corn-soybean meal basal diet containing 0,25,50,or 100 mg/kg ASTA for 6 weeks.Results:Semen quality in the ASTA groups remarkably improved than that in the control group,and antioxidant activities,the abilities to scavenge hydroxyl radicals and superoxide anions,increased gradually with ASTA addition(P<0.05).In addition,the mRNA levels of antioxidant enzymes as well as the mRNA and protein levels of the mitogen-activated protein kinase(MAPK)and nuclear factor-erythroid 2-related factor 2(Nrf2)were markedly increased in the 50-100 mg/kg ASTA group(P<0.05).Conclusions:Collectively,these results demonstrate that dietary ASTA may improve semen quality by increasing antioxidant enzyme activities and the ability to scavenge hydroxyl radicals,which may be related to upregulation of the MAPK/Nrf2 pathway. | Shan Gao Nuo Heng Fang Liu Yong Guo Yu Chen Liang Wang Hemin Ni Xihui Sheng Xiangguo Wang Kai Xing Longfei Xiao Xiaolong Qi | 2022 | Journal of Animal Science and Biotechnology2022，13，2： | 2 |
| 17 | Experimental study on the molecular dimension and configuration of polymer and its flow characteristics from electrolyte effect显示文摘 | Lu Xiangguo Wang Xiaoyan Jiang Weidong | 2009 | Chinese Journal of Chemistry2009，27，4： | 1 |
| 18 | Polymorphisms of nucleotide-excision repair genes may contribute to sperm DNA fragmentation and male infertility显示文摘 | Aihua Gu Guixiang Ji Yong Zhou Yan Long Xiangguo Shi Guangbo Fu Shoulin Wang Ling Song Xinru Wang | 2010 | Reproductive BioMedicine Online2010，，5： | 1 |
| 19 | Bioluminescence imaging of caspase-3 activity in mouse liver显示文摘 | Qiuxia Fu Xiangguo Duan Shaoduo Yan Licui Wang Yong Zhou Shuaizheng Jia Juan Du Xiaohui Wang Yuhua Zhang Linsheng Zhan | 2013 | Apoptosis2013，，8： | 1 |
| 20 | Intra-host Ebola viral adaption during human infection显示文摘The onsite next generation sequencing(NGS)of Ebola virus(EBOV)genomes during the 2013–2016 Ebola epidemic in Western Africa provides an opportunity to trace the origin,transmission,and evolution of this virus.Herein,we have diagnosed a cohort of EBOV patients in Sierra Leone in 2015,during the late phase of the outbreak.The surviving EBOV patients had a recovery process characterized by decreasing viremia,fever,and biochemical parameters.EBOV genomes sequenced through the longitudinal blood samples of these patients showed dynamic intra-host substitutions of the virus during acute infection,including the previously described short stretches of 13 serial TNC mutations.Remarkably,within individual patients,samples collected during the early phase of infection possessed Ts at these nucleotide sites,whereas they were replaced by Cs in samples collected in the later phase,suggesting that these short stretches of TNC mutations could emerge independently.In addition,up to a total of 35 nucleotide sites spanning the EBOV genome were mutated coincidently.Our study showed the dynamic intra-host adaptation of EBOV during patient recovery and gave more insight into the complex EBOV-host interactions. | William JLiu Weifeng Shi Wuyang Zhu Cong Jin Shumei Zou Ji Wang Yuehua Ke Xiaofeng Li Mi Liu Tao Hu Hang Fan Yigang Tong Xiang Zhao Wenbin Chen Yuhui Zhao Di Liu Gary Wong Chengchao Chen Chunyu Geng Weiwei Xie Hui Jiang Idrissa Laybor Kamara Abdul Kamara Matt Lebby Brima Kargbo Xiangguo Qiu Yu Wang Xiaofeng Liang Mifang Liang Xiaoping Dong Guizhen Wu George F.Gao Yuelong Shu | 2019 | Biosafety and Health2019，1，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员