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| 1 | Effect of Liuweibuqi capsule, a Chinese patent medicine, on the JAK1/STAT3 pathway and MMP9/TIMP1 in a chronic obstructive pulmonary disease rat model显示文摘OBJECTIVE: To observe effect of Liuweibuqi Capsule, a Traditional Chinese Medicine(TCM), on the janus kinase(JAK)/signal transducer and activator of transcription(STAT) pathway and matrix metalloproteinases(MMPs) in a chronic obstructive pulmonary disease(COPD) rat model with lung deficiency in terms of TCM's pattern differentiation.METHODS: Rats were randomly divided into a normal group, model group, Liuweibuqi group, Jinshuibao group, and spleen aminopeptidase group(n=10). Aside from the normal group, all rats were ex-posed to smoke plus lipopolysaccharide tracheal instillation to establish the COPD model with lung deficiency. Models were established after 28 days and then the normal and model groups were given normal saline(0.09 g/kg), Liuweibuqi group was given Liuweibuqi capsule(0.35 g/kg), Jinshuibao group was given Jinshuibao capsules(0.495 g/kg), and the spleen group was given spleen aminopeptidase(0.33 mg/kg), once a day for 30 days. Changes in symptoms, signs, and lung histology were observed. Lung function was measured with a spirometer. Serum cytokines were detected using enzyme-linked immunosorbent assay, and changes in the JAK/STAT pathway, MMP-9, and MMPs inhibitor1(TIMP1) were detected by immunohistochemistry, RT-PCR, and western blotting, respectively.RESULTS: Compared with the normal group, lung tissue was damaged, and lung function was reduced in the model control group. Additionally, the levels of interleukin(IL)-1β, γ interferon(IFN-γ), and IL-6 were higher, while IL-4 and IL-10 were lower in the model control group than those in the normal group. The expressions of JAK1, STAT3, p-STAT3,and MMP-9 m RNA and protein in lung tissue were higher, and TIMP1 m RNA and protein was lower in the model group compared with the normal group.After treatment, compared with the model group,the expression of inflammatory cytokines was lower in each treatment group, and expressions of JAK/STAT pathway, MMPs were lower. Compared with the positive control groups, the Jinshuibao and spleen aminopeptidase groups, lung function was better, and JAK1, STAT3, and p-STAT3 protein were lower and TIMP1 was higher in the Liuweibuqi group.CONCLUSION: Liuweibuqi capsules can improve the symptoms of COPD possibly by regulating the expression of the JAK1/STAT3 pathway and MMP9/TIMP1. | Wang Chengyang Li Zegen Liu Xiangguo Peng Qinghe Li Fang Li Da Wang Chuanbo | 2015 | Journal of Traditional Chinese Medicine2015，35，1： | 23 |
| 2 | ZmCOL3, a CCT gene represses flowering in maize by interfering with the circadian clock and activating expression of ZmCCT显示文摘Flowering time is a trait vital to the adaptation of flowering plants to different environments.Here, we report that CCT domain genes play an important role in flowering in maize(Zea mays L.).Among the 53 CCT family genes we identified in maize, 28 were located in flowering time quantitative trait locus regions and 15 were significantly associated with flowering time, based on candidate-gene association mapping analysis.Furthermore, a CCT gene named ZmCOL3 was shown to be a repressor of flowering.Overexpressing ZmCOL3 delayed flowering time by approximately 4 d, in either long-day or short-day conditions.The absence of one cytosine in the ZmCOL3 3'UTR and the presence of a 551 bp fragment in the promoter region are likely the causal polymorphisms contributing to the maize adaptation from tropical to temperate regions.We propose a modified model of the maize photoperiod pathway, wherein ZmCOL3 acts as an inhibitor of flowering either by transactivating transcription of ZmCCT, one of the key genes regulating maize flowering, or by interfering with the circadian clock. | Minliang Jin Xiangguo Liu Wei Jia Haijun Liu Wenqiang Li Yong Peng Yanfang Du Yuebin Wang Yuejia Yin Xuehai Zhang Qing Liu Min Deng Nan Li Xiyan Cui Dongyun Hao Jianbing Yan | 2018 | Journal of Integrative Plant Biology2018，60，6： | 14 |
| 3 | Coal mining GPS subsidence monitoring technology and its application显示文摘We proved theoretically that geodetic height,measured with Global Positioning System(GPS),can be applied directly to monitor coal mine subsidence.Based on a Support Vector Machine(SVM) model,we built a regional geoid model with a Gaussian Radial Basis Function(RBF) and the technical scheme for GPS coal mine subsidence monitoring is presented to provide subsidence information for updating the regional Digital Elevation Model(DEM).The theory proposed was applied to monitor mining subsidence in an Inner Mongolia coal mine in China.The scheme established an accurate GPS reference network and a comprehensive leveling conjunction provided the normal height of all GPS control points.According to the case study,the SVM model to establish geoid-model is better than a polynomial it or a Genetic Algorithm based Back Propagation(GA-BP) neural network.GPS-RTK measurements of coal mine subsidence information can be quickly acquired for updating the DEM. | Wang Jian Peng Xiangguo Xu Chang hui | 2011 | Mining Science and Technology2011，21，4： | 6 |
| 4 | MATERIALS INFORMATICS AND STUDY ON ITS FURTHER DEVELOPMENT显示文摘Materials informatics is a cross discipline combining materials science and information science. The concept of materials informatics was introduced and expounded. The current status of research and application of materials informatics was analyzed. And the main tasks and research areas of materials informatics were summarized. Then the foundation and significance of its development in China was discussed. Lastly the development vision of materials informatics was proposed. | WEI Qunyi PENG Xiaodong LIU Xiangguo XIE Weidong | 2006 | Chinese Science Bulletin2006，51，4： | 6 |
| 5 | Elastic Scattering of 7Be on Pb Target显示文摘 | Yang Yanyun Wang Jiansong Wang Qi Huang Meirong Ma Junbing Ma Peng Cao Xiguang Han Jianlong Bai Zhen Jin Shilong Hu Qiang Jin Lei Chen Jiangbo Zhang Xueying Chen Ruofu Hu Zhengguo Xu Shiwei Zhen Chuan Xu Zhiguo Xu Hushan Duan Liming Sun Zhiyu Chen Zhiqiang He Jianjun Li Songlin Lei Xiangguo Fu Fen Zhang Xueheng Yuan Xiaohua Du Chengming Yan Xinshuang Hu Jun Tang Shuwen Ye Ruiping Yang Kun Shi Fudong Zhang Wei Chen Ze Li Long Xu Xing Liu Longxiang Zhang Liyong Lin Qingyun Gou Boxing Xu Ge Zhou Xionghong Zhang Yuhu Xiao Guoqing | 2011 | IMP & HIRFL Annual Report2011，，1： | 4 |
| 6 | Confining TiO_2 Nanotubes in PECVD-Enabled Graphene Capsules Toward Ultrafast K-Ion Storage: In Situ TEM/XRD Study and DFT Analysis显示文摘Titanium dioxide(TiO2) has gained burgeoning attention for potassium-ion storage because of its large theoretical capacity,wide availability,and environmental benignity.Nevertheless,the inherently poor conductivity gives rise to its sluggish reaction kinetics and inferior rate capability.Here,we report the direct graphene growth over TiO2 nanotubes by virtue of chemical vapor deposition.Such conformal graphene coatings effectively enhance the conductive environment and well accommodate the volume change of TiO2 upon potassiation/depotassiation.When paired with an activated carbon cathode,the graphene-armored TiO2 nanotubes allow the potassium-ion hybrid capacitor full cells to harvest an energy/power density of 81.2 Wh kg-1/3746.6 W kg-1.We further employ in situ transmis sion electron microscopy and ope rando X-ray diffraction to probe the potassium-ion storage behavior.This work offers a viable and versatile solution to the anode design and in situ probing of potassium storage technologies that is readily promising for practical applications. | Jingsheng Cai Ran Cai Zhongti Sun Xiangguo Wang Nan Wei Feng Xu Yuanlong Shao Peng Gao Shixue Dou Jingyu Sun | 2020 | Nano-Micro Letters2020，12，9： | 2 |
| 7 | Fischer-Trop- sch Synthesis on Fe-Mn Ultrafine Catalysts 显示文摘 | Li Xiangguo Zhong Bing Peng Shaoyi | 1994 | Catal Lett1994，23，34： | 1 |
| 8 | Preparation technologies and applications of strontium-magnesium master alloys 显示文摘 | Liu Xiangguo Peng Xiaodong Xie Weidong | 2005 | Materials Science Forum2005，48，： | 1 |
| 9 | First Observation of Signature Inversion in πh_(9/2) ■ vi_(13/2) Oblate Band in ^(190)Tl显示文摘The high-spin states of 190Tl, populated via the 160Gd(35Cl, 5n)190Tl fusion-evaporation reaction at 167 and 175 MeV beam energies, have been investigated by in-beam γ-ray spectroscopy. Based on the experiment measured results, together with references to the previous in-beam work and the studies of the 194Bi αdecay, the level scheme of 190Tl has been established as shown in Fig.1. Spins for the levels above the 300 keV 10-state were proposed from the measured DCO and γ-ray anisotropy results. It is the first time that spin | Xie Chengying Zhou Xiaohong Zhang Yuhu Guo Yingxiang Lei Xiangguo Song Litao Wang Hualei Liu Minliang Zheng Yong Guo Wentao Yu Haiping Luo Peng Wen Shuxian Zhu Lihua Wu Xiaoguang | 2004 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2004，，1： | 0 |
| 10 | 2 - 30 Progress in Analyzing RIBLL1 17F+p Experimental Data显示文摘 | He Jianjun Hu Jun Xu Shiwei Chen Zhiqiang Zhang Xueying Wang Jiansong Yu Xiangqing Li Long Zhang Liyong Yang Yanyun Ma Peng Wang Hongwei Tian Wendong Zhang Xueheng Su Jun Li Ertao Hu Zhengguo Guo Zhongyan Xu Xing Yuan Xiaohua Lu Wan Lei Xiangguo Yu Yuhong Tang Shuwen Ye Ruiping Chen Jinda Jin Shilun Du Chengming Wang Shitao Ma Junbing Liu Longxiang Bai Zhen Sun Zhiyu Li Xiangqing Zhang Yuhu Zhou Xiaohong Xu Hushan | 2010 | IMP & HIRFL Annual Report2010，，1： | 0 |
| 11 | Identification of a Low-spin Isomer in ^(176)Ir显示文摘Theβ+/EC decay of doubly odd 176Ir has been studied via the 146Nd(35Cl,5nγ) heavy ion fusion evaporation reaction at the Sector-Focusing Cyclotron (SFC) accelerator in the Institute of Modern Physics (IMP), Lanzhou. A 210 MeV 35C1 beam from the cyclotron entered a helium-filed target chamber, | Wang Hualei, Zhang Yuhu, Zhou Xiaohong, Guo Yingxiang, Lei Xiangguo, Xu Shuwei Xie Yuanxiang,Liu Minliang, Zheng Yong, Xing Yebing, Xie Chengying, Song Litao Lou Peng, Yu Haiping, Guo Wentao,Ding Huajie and Niu Yanning | 2005 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2005，，1： | 0 |
| 12 | Machine learning accelerated carbon neutrality research using big data-from predictive models to interatomic potentials显示文摘Carbon neutrality has been proposed as a solution for the current severe energy and climate crisis caused by the overuse of fossil fuels, and machine learning(ML) has exhibited excellent performance in accelerating related research owing to its powerful capacity for big data processing. This review presents a detailed overview of ML accelerated carbon neutrality research with a focus on energy management, screening of novel energy materials, and ML interatomic potentials(MLIPs), with illustrations of two selected MLIP algorithms: moment tensor potential(MTP) and neural equivariant interatomic potential(NequIP). We conclude by outlining the important role of ML in accelerating the achievement of carbon neutrality from global-scale energy management, unprecedented screening of advanced energy materials in massive chemical space, to the revolution of atomicscale simulations of MLIPs, which has the bright prospect of applications. | WU LingJun XU ZhenMing WANG ZiXuan CHEN ZiJian HUANG ZhiChao PENG Chao PEI XiangDong LI XiangGuo MAILOA Jonathan P HSIEH Chang-Yu WU Tao YU Xue-Feng ZHAO HaiTao | 2022 | Science China(Technological Sciences)2022，65，10： | 0 |
| 13 | Determination of ^(15)N in Enriched Potassium Nitrate显示文摘Determination of ^(15)N in Enriched Potassium NitrateDeterminationof^(15)NinEnrichedPotassiumNitrate￥ZhangWeicheng;PengXiuruan... | Zhang Weicheng Peng Xiuru and Let Xiangguo | 1995 | IMP & HIRFL Annual Report1995，，0： | 0 |
| 14 | Investigation of Proton Resonant Properties in laNe via 17F+p and Its Astrophysical Implications for 14O(α,p)17F Stellar Reaction显示文摘 | Hu Jun He Jianjun Xu Shiwei Chen Zhiqiang Zhang Xueying Wang Jiansong Yu Xiangqing Li Long Zhang Liyong Yang Yanyun Ma Peng Wang Hongwei Tian Wendong Yuan Xiaohua Lu Wan Zhang Xueheng SuJun Li Ertao Hu Zhengguo Guo Zhongya n Xu Xing Lei Xiangguo Yu Yuhong Tang Shuwen Ye Ruiping Chen Jinda Jin Shilun Du Chengming Wang Shitao Ma Junbing Liu Longxiang Bai Zhen Sun Zhiyu Li Xiangqing Zhang Yuhu Zhou Xiaohong Xu Hushan | 2009 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2009，，1： | 0 |
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