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| 1 | Ideal cardiovascular health and incidence of atherosclerotic cardiovascular disease among Chinese adults:the China-PAR project显示文摘Existing evidence on the relationship between cardiovascular health(CVH) metrics and cardiovascular disease(CVD) was primarily derived from western populations. We aimed to evaluate the benefits of ideal CVH metrics on preventing incident atherosclerotic CVD(ASCVD) in Chinese population. This study was conducted among 93,987 adults from the China-PAR project(Prediction for ASCVD Risk in China) who were followed up until 2015. Cox proportional hazard regression models were used to estimate the hazard ratios(HRs) and their corresponding 95% confidence intervals(CIs) of CVH metrics for the risk of ASCVD, including coronary heart disease(CHD), stroke and ASCVD death. We further estimated the population-attributable risk percentage(PAR%) of these metrics in relation to each outcome. We observed gradient inverse associations between the number of ideal CVH metrics and ASCVD incidence. Compared with participants having ≤2 ideal CVH metrics, the multivariable-adjusted HRs(95% CIs) of ASCVD for those with 3, 4, 5, 6 and 7 ideal CVH metrics were 0.83(0.74–0.93), 0.66(0.59–0.74), 0.55(0.48–0.61), 0.44(0.38–0.50) and 0.24(0.18–0.31), respectively(P for trend <0.0001). Approximately 62.1% of total ASCVD, 38.7% of CHD, 66.4% of stroke, and 60.5% of ASCVD death were attributable to not achieving all the seven ideal CVH metrics. After adjusting effects of ideal health factors, having four ideal health behaviors could independently bring adults health benefits in preventing 17.4% of ASCVD, 18.0% of CHD, 16.7% of stroke, and 10.1% of ASCVD death. Among all the seven CVH metrics, to keep with ideal blood pressure(BP) implied the largest public health gains against various ASCVD events(PAR% between 33.0% and 47.2%), while ideal diet was the metric most difficult to be achieved in the long term. Our study indicates that the more ideal CVH metrics adults have, the less ASCVD burden there is in China. Special efforts of health education and behavior modification should be made on keeping ideal BP and dietary habits in general Chinese population to prevent the epidemic of ASCVD. | Chao Han Fangchao Liu Xueli Yang Jichun Chen Jianxin Li Jie Cao Ying Li Chong Shen Ling Yu Zhendong Liu Xianping Wu Liancheng Zhao Dongshen Hu Xiangfeng Lu Xigui Wu Dongfeng Gu | 2018 | Science China(Life Sciences)2018，61，5： | 60 |
| 2 | Predicting lifetime risk for developing atherosclerotic cardiovascular disease in Chinese population:the China-PAR project显示文摘Evidence on the lifetime risk for atherosclerotic cardiovascular disease(ASCVD) is insufficient;yet,estimating an individual's lifetime risk allows for a comprehensive assessment of ASCVD burden.We developed and validated lifetime risk prediction equations for ASCVD using four large and ongoing prospective cohorts of Chinese,the China-PAR project(Prediction for ASCVD Risk in China).Sexspecific equations were developed using two cohorts(as the derivation cohort) of 21,320 participants.Two other independent cohorts with 14,123 and 70,838 participants were used for their external validation,respectively.We evaluated both calibration and discrimination measures for model performance.Furthermore,we estimated ASCVD-free years lost or excess absolute risk attributable to high 10-year risk(!10.0%) and/or high lifetime risk(!32.8%).After 12.3 years' follow-up of the derivation cohort,1048 ASCVD events and 1304 non-ASCVD deaths were identified.Our sex-specific equations had good internal validation,with discriminant C statistics of 0.776(95% confidence interval [CI]:0.757–0.794) and 0.801(95% CI:0.778–0.825),and calibration χ~2 of 9.2(P = 0.418) and 5.6(P = 0.777) for men and women,respectively.Good external validation was also demonstrated with predicted rates closely matched to the observed ones.Compared with men having both low 10-year and low lifetime risk,men would develop ASCVD 3.0,4.6 and 8.6 years earlier if they had high 10-year risk alone,high lifetime risk alone,or both high 10-year and high lifetime risk at the index age of 35 years,respectively.We developed wellperformed lifetime risk prediction equations that will help to identify those with the greatest potential to avert ASCVD burden after implementation of innovative clinical and public health interventions in China. | Fangchao Liu Jianxin Li Jichun Chen Dongsheng Hu Ying Li Jianfeng Huang Xiaoqing Liu Xueli Yang Jie Cao Chong Shen Ling Yu Zhendong Liu Xianping Wu Liancheng Zhao Xigui Wu Dongfeng Gu Xiangfeng Lu | 2018 | Science Bulletin2018，63，12： | 30 |
| 3 | Fruit and vegetable consumption,cardiovascular disease,and all-cause mortality in China显示文摘Evidence about the response patterns of fruit and vegetable consumption with the risk of cardiovascular disease(CVD)and allcause mortality was inconsistent.These associations were examined using a large-scale,population-based Chinese cohort comprising 100,728 participants.A food-frequency questionnaire was used to assess fruit and vegetable consumption.Outcomes were ascertained by interviewing individuals or their proxies and checking hospital records or death certificates.Cox proportional hazards regression was used to calculate hazard ratios(HRs)with 95% confidence intervals(CIs).At the 736,668 person-years of follow-up,3,677 CVD cases and 5,466 deaths were identified.The multivariable-adjusted HRs for CVD across increasing quartiles of total fruit and vegetable consumption were 1(reference),0.94(95%CI=0.85-1.04),0.89(95%CI=0.80-0.98),and 0.85(95%CI=0.77-0.95).Moreover,participants in the highest quartile displayed a 13% lower risk of all-cause mortality(HR=0.87;95%CI=0.80-0.95).A nonlinear dose-response relation was found for CVD,without additional benefits beyond a consumption of600 g d-1,whereas the all-cause mortality risk decreased along with higher consumption,with a linear trend.These associations remained significant for fruit consumption but not for vegetable consumption.Our findings indicated that greater fruit and vegetable consumption was significantly associated with a lower risk of CVD and all-cause mortality.Increasing fruit and vegetable consumption,especially fruit,in the general population would prevent CVD and premature mortality. | Jun Wang Fangchao Liu Jianxin Li Keyong Huang Xueli Yang Jichun Chen Xiaoqing Liu Jie Cao Shufeng Chen Chong Shen Ling Yu Fanghong Lu Xianping Wu Liancheng Zhao Ying Li Dongsheng Hu Jianfeng Huang Dongfeng Gu Xiangfeng Lu | 2022 | Science China(Life Sciences)2022，65，1： | 8 |
| 4 | Associations of egg consumption with incident cardiovascular disease and all-cause mortality显示文摘Eggs are nutrient-dense while also loaded with abundant cholesterol, thus making the public hesitant about their consumption.We conducted the study to investigate if egg consumption is associated with incident cardiovascular disease(CVD) and all-cause mortality. Using the project of Prediction for Atherosclerotic Cardiovascular Disease Risk in China, we included 102,136 adults free of CVD and assessed their egg consumption with food-frequency questionnaires. CVD endpoints and all-cause mortality were confirmed during follow-ups by interviewing participants or their proxies and checking hospital records/death certificates.The HRs(95% CIs) were calculated using the cohort-stratified Cox regression models. During 777,163 person-years of followup, we identified 4,848 incident CVD and 5,511 deaths. U-shaped associations of egg consumption with incident CVD and allcause mortality were observed. Compared with consumption of 3–<6/week, the multivariable-adjusted HRs(95% CIs) of <1/week and ≥10/week for incident CVD were 1.22(1.11 to 1.35) and 1.39(1.28 to 1.52), respectively. The corresponding HRs(95% CIs) for all-cause mortality were 1.29(1.18 to 1.41) and 1.13(1.04 to 1.24). Our findings identified that both low and high consumption were associated with increased risk of incident CVD and all-cause mortality, highlighting that moderate egg consumption of 3–<6/week should be recommended for CVD prevention in China. | Xue Xia Fangchao Liu Xueli Yang Jianxin Li Jichun Chen Xiaoqing Liu Jie Cao Chong Shen Ling Yu Yingxin Zhao Xianping Wu Liancheng Zhao Ying Li Jianfeng Huang Xiangfeng Lu Dongfeng Gu | 2020 | Science China(Life Sciences)2020，63，9： | 7 |
| 5 | Telmisartan promotes proliferation and differentiation of endothelial progenitor cells via activation of Akt显示文摘 | Cao Zheng Yang Yong Hua Xianping Wu Ruixia Wang Junfeng Zhou Ming Zhan Zhongqun Chen Pingying | 2014 | Chinese Medical Journal2014，，1： | 5 |
| 6 | Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus—Sichuan Province,China,2019显示文摘What is already known about this topic?After the type 2 strain of the live,attenuated poliovirus vaccine was withdrawn globally in 2016,any identification of a type 2 poliovirus is a Public Health Emergency of International Concern.A vaccinederived type 2 poliovirus(VDPV2)was identified in Sichuan,prompting an urgent,comprehensive investigation and response.What is added by this report?Type 2 monovalent,live,attenuated oral poliovirus vaccine(mOPV2)is being used to respond to the numerous VDPV2 outbreaks seen around the world.In contrast,the response in Sichuan used Sabin strain inactivated poliovirus(sIPV)to stop circulation of the VDPV2.In the 6 months following the vaccination response,there have been no VDPV2s detected in Sichuan,despite extensive search.What are the implications for public health practices?Further search for the VDPV2 must continue in order to determine whether transmission has been stopped.The ongoing investigation and response to the Sichuan VDPV2 is providing evidence to the Global Polio Eradication Initiative on managing VDPV2 outbreaks. | Jiushun Zhou Ning Wen Yong Zhang Qi Qi Chunxiang Fan Dongmei Yan Xiaoping Zhu Lixin Hao Shuangli Zhu Yu Liu Xiaozhen Ma Chao Ma Lei Nan Yong Chen Qianli Ma Cheng Wang Kun Deng Lei Cao Ge Shao Xianxiang Ding Hong Yang Zhijie An Lance ERodewald Aiqiang Xu Huaqing Wang Zijian Feng Zundong Yin Xianping Wu Wenbo Xu | 2020 | China CDC weekly2020，2，11： | 3 |
| 7 | Convergence of Markov decision processes with constraints and state-action dependent discount factors显示文摘This paper is concerned with the convergence of a sequence of discrete-time Markov decision processes(DTMDPs)with constraints,state-action dependent discount factors,and possibly unbounded costs.Using the convex analytic approach under mild conditions,we prove that the optimal values and optimal policies of the original DTMDPs converge to those of the'limit'one.Furthermore,we show that any countablestate DTMDP can be approximated by a sequence of finite-state DTMDPs,which are constructed using the truncation technique.Finally,we illustrate the approximation by solving a controlled queueing system numerically,and give the corresponding error bound of the approximation. | Xiao Wu Xianping Guo | 2020 | Science China Mathematics2020，63，1： | 2 |
| 8 | First passage Markov decision processes with constraints and varying discount factors显示文摘这份报纸与多限制,州依赖者的折扣因素,和可能无界的费用在可数的州、紧缩的 Borel 行动空格集中于分离时间的 Markov 决定处理的第一个段落(DTMDP ) 的抑制 optimality 问题(警察) 。借助于一条政策的一项所谓的职业措施的性质,我们证明抑制 optimality 问题等价于一(无限维) 职业的集合上的线性编程与一些限制测量,并且因此在合适的条件下面证明一条最佳的政策的存在。用在抑制 optimality 问题和线性编程之间的等价,而且,我们为有限状态和行动的盒子获得一条最佳的政策的一种准确形式。作为一个例子,最后,一个控制排队系统被给说明我们的结果。 | Xiao WU Xiaolong ZOU Xianping GUO | 2015 | Frontiers of Mathematics in China2015，10，4： | 2 |
| 9 | Adverse associations of sedentary behavior with cancer incidence and all-cause mortality:A prospective cohort study显示文摘Background:Inconsistent results have been reported in developed countries for relationships between sedentary behavior and cancer incidence and mortality,and evidence from the Chinese population is scarce.This study aimed to investigate such relationships in large Chinese population-based prospective cohorts and to explore the joint effect and interaction of sedentary behavior and moderate-to-vigorous physical activity(MVPA)on these relationships.Methods:We included 95,319 Chinese adults without cancer from 3 large cohorts and assessed their sedentary behavior and physical activity with a unified questionnaire.Cancer incidence and mortality were confirmed by interviewing participants or their proxies and checking hospital records and death certificates.Hazard ratios(HRs)and 95%confidence intervals(95%CIs)for cancer and mortality were estimated using Cox proportional hazards regression models.Results:During 559,002 person-years of follow-up,2388 cancer events,1571 cancer deaths,and 4562 all-cause deaths were recorded.Sedentary behavior was associated with increased risk of developing cancer and deaths in a doseresponse manner.The multivariable-adjusted HRs(95%CIs)were the following:HR=1.16,95%CI:1.01-1.33;HR=1.24,95%CI:1.04-1.48;and HR=1.15,95%CI:1.04-1.28 for cancer incidence,cancer mortality,and all-cause mortality,respectively,for those having≥10 h/day of sedentary time compared with those having<6 h/day of sedentary time.Sedentary populations(≥10 h/day)developed cancer or died 4.09 years and 2.79 years earlier,respectively,at the index age of 50 years.Failure to achieve the recommended level of MVPA may further aggravate the adverse associations,with the highest cancer and mortality risks being observed among participants with both≥10 h/day of sedentary time and<150 min/week of MVPA.Limitations of this study include the fact that physical activity information was obtained via questionnaire instead of objective measurement and that there were insufficient incident cases for the analysis of associations between sedentary behavior and site-specific cancers.Conclusion:Sedentary behavior was associated with an increased risk of cancer and all-cause mortality among Chinese adults,especially for those with≥10 h/day of sedentary time.It is necessary to reduce sedentary time,in addition to increasing MVPA levels,for the prevention of cancer and premature death. | Yuan Lin Qiong Liu Fangchao Liu Keyong Huang Jianxin Li Xueli Yang Xinyan Wang Jichun Chen Xiaoqing Liu Jie Cao Chong Shen Ling Yu Fanghong Lu Xianping Wu Liancheng Zhao Ying Li Dongsheng Hu Xiangfeng Lu Jianfeng Huang Dongfeng Gu | 2021 | Journal of Sport and Health Science2021，10，5： | 2 |
| 10 | Formation of an Intermetallic Phase by Crystallization in The Cr-Si-Ni-Al Amorphous Film显示文摘 | Dong Xianping Wu Jiansheng | 2003 | Alloys Compd2003，359，： | 1 |
| 11 | The Influence of Zirconium on the Crystallization Behavior and Electrical Properties of Cr-Si-Al Resistive Films显示文摘 | Dong Xianping Wu Jiansheng | 2004 | Mater Sci Eng A2004，371，： | 1 |
| 12 | The Crystallization of Amorphous Cr-Si-Ni-Al Films-Nucleation and Growth of Intermetallic Phase Cr(Al, Si) 显示文摘 | Dong Xianping Wu Jiansheng Mao Lizhong | 2003 | Intermetallics2003，11，： | 1 |
| 13 | Optimal stopping investment in a logarithmic utility-based portfolio selection problem显示文摘Background:In this paper,we study the right time for an investor to stop the investment over a given investment horizon so as to obtain as close to the highest possible wealth as possible,according to a Logarithmic utility-maximization objective involving the portfolio in the drift and volatility terms.The problem is formulated as an optimal stopping problem,although it is non-standard in the sense that the maximum wealth involved is not adapted to the information generated over time.Methods:By delicate stochastic analysis,the problem is converted to a standard optimal stopping one involving adapted processes.Results:Numerical examples shed light on the efficiency of the theoretical results.Conclusion:Our investment problem,which includes the portfolio in the drift and volatility terms of the dynamic systems,makes the problem including multi-dimensional financial assets more realistic and meaningful. | Xun Li Xianping Wu Wenxin Zhou | 2017 | Financial Innovation2017，3，1： | 1 |
| 14 | Seasonal variation in blood pressure and its relationship with outdoor temperature in 10 diverse regions of China: the China Kadoorie Biobank显示文摘 | Sarah Lewington Liming Li Paul Sherliker Yu Guo Iona Millwood Zheng Bian Gary Whitlock Ling Yang Rory Collins Junshi Chen Xianping Wu Shaojie Wang Yihe Hu Li Jiang Liqiu Yang Ben Lacey Richard Peto Zhengming Chen | 2012 | Journal of Hypertension2012，，7： | 1 |
| 15 | Folded waveguide slow wave structure with modified circular bends显示文摘 | CAI Jun FENG Jinjun WU Xianping | 2014 | IEEETransactions on Electron Devices2014，61，10： | 1 |
| 16 | Traveling wave tube harmonic amplifier in terahertz and experiment demonstration显示文摘 | CAI Jun FENG Jinjun WU Xianping | 2015 | IEEE Transactions on Electron Devices2015，62，2： | 1 |
| 17 | 显示文摘 | Zhang Yuqin Dong Xianping Wu Jiansheng | 2004 | Mater Sci Eng B2004，113，： | 1 |
| 18 | Novel hybrid group key agreement for sensitive information systems显示文摘 | XIANPING WU HUY HOANG NGO PHU DUNG LE | 2010 | JCIT : Journai of Convergence Information Technology2010，5，1： | 1 |
| 19 | An individual and group authentication model for wireless network services显示文摘 | HUY HOANG NGO XIANPING WU PHU DUNG LE | 2010 | JCIT: Journal of Convergence Information Technology2010，5，1： | 1 |
| 20 | Systematic analysis of artificial intelligence in the era of industry 4.0显示文摘Artificial Intelligence has been playing a profound role in the global economy,social progress,and people’s daily life.With the increasing capabilities and accuracy of AI,the application of AI will have more impacts on manufacturing and service areas in the era of industry 4.0.This study conducts a systematic literature review to study the state-of-the-art on AI in industry 4.0.This paper describes the development of industries and the evolution of AI.This paper also identifies that the development and application of AI will bring not only opportunities but also challenges to industry 4.0.The findings provide a valuable reference for researchers and practitioners through a multi-angle systematic analysis of AI.In the era of industry 4.0,AI system will become an innovative and revolutionary assistance to the whole industry. | Weiru Chen Wu He Jiayue Shen Xin Tian Xianping Wang | 2023 | Journal of Management Analytics2023，10，1： | 0 |
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