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| 1 | Proteomic analysis of roots growth and metabolic changes under phosphorus deficit in maize (Zea mays L.) plants显示文摘 | Li, KP Xu, CZ Zhang, KW Yang, AF Zhang, JR | 2007 | 中国生物学文摘2007，21，11： | 16 |
| 2 | Hypertrophic adenoids in patients with nasopharyngeal carcinoma:appearance at magnetic resonance imaging before and after treatment显示文摘Introduction:Patients with nasopharyngeal carcinoma(NPC) sporadically develop abnormal adenoids.Nasopharyngeal adenoids are usually included in the gross tumor volume(GTV) but may have different therapeutic responses than tumor tissue.Therefore,distinguishing adenoids from tumor tissue may be required for precise and efficient chemoradiotherapy and radiotherapy.We characterized nasopharyngeal adenoids and investigated the therapeutic responses of NPC and nasopharyngeal adenoids using magnetic resonance imaging(MRI).Methods:MRI data from 40 NPC patients with a coexisting adenoid mass before and after treatment were analyzed.The features of the adenoid masses,including location,striped appearance,size,interface,symmetry/asymmetry,and cysts,were evaluated.Treatment response were scored according to the World Health Organization guidelines.Results:A striped appearance was observed in 36 cases before treatment and in all cases after treatment.In these 36 cases,the average GTVs including and excluding the uninvolved adenoids were 19.8 cm^3 and 14.8 cm^3,respectively.The average percentage change after excluding the uninvolved adenoids from the GTV was 31.0%.Stable disease in the adenoids was identified in 27(96.4%) of 28 patients after neoadjuvant chemotherapy,while NPC clearly regressed.Partial adenoid responses were identified in 33(82.5%) of 40 patients at 3 months after chemoradiotherapy or radiotherapy,whereas complete tumor responses were achieved in all patients.Six months after treatment,the adenoids continued to atrophy but did not disappear,and tumor recurrence was not found.Conclusions:Nasopharyngeal adenoids and carcinoma tissue in NPC patients can be distinguished by using MRI and have different responses to chemoradiotherapy and radiotherapy.These findings contribute to better delineating the GTV of NPC,based on which spatially optimized strategies can be developed to render precise and efficient chemoradiotherapy and radiotherapy.Additionally,we observed a clear difference in the responses of these two tissue types to current therapies.This finding may reduce or avoid unnecessary biopsies or overtreatment. | Yao-Pan Wu Pei-Qiang Cai Li Tian Jie-Hua Xu Richard Alan Mitteer Jr Yi Fan Zhenfeng Zhang | 2015 | Chinese Journal of Cancer2015，34，3： | 4 |
| 3 | PM_(2.5)and water-soluble inorganic ion concentrations decreased faster in urban than rural areas in China显示文摘We investigated variations of PM_(2.5)and water-soluble inorganic ions chemical characteristics at nine urban and rural sites in China using ground-based observations.From 2015 to 2019,mean PM_(2.5)concentration across all sites decreased by 41.9μg/m~3with a decline of 46%at urban sites and 28%at rural sites,where secondary inorganic aerosol(SIAs)contributed to 21%(urban sites)and 17%(rural sites)of the decreased PM_(2.5).SIAs concentrations underwent a decline at urban locations,while sulfate(SO_(4)^(2–)),nitrate(NO_(3)^(–)),and ammonium(NH_(4)^(+))decreased by 49.5%,31.3%and 31.6%,respectively.However,only SO_(4)^(2–)decreased at rural sites,NO_(3)^(–)increased by 21%and NH_(4)^(+)decreased slightly.Those changes contributed to an overall SIAs increase in 2019.Higher molar ratios of NO_(3)^(–)to SO_(4)^(2–)and NH_(4)^(+)to SO_(4)^(2–)were observed at urban sites than rural sites,being highest in the heavily polluted days.Mean molar ratios of NH_(3)/NH_xwere higher in 2019 than 2015 at both urban and rural sites,implying increasing NH_xremained as free NH_(3).Our observations indicated a slower transition from sulfate-driven to nitrate-driven aerosol pollution and less efficient control of NO_(x)than SO_(2)related aerosol formation in rural regions than urban regions.Moreover,the common factor at urban and rural sites appears to be a combination of lower SO_(4)^(2–)levels and an increasing fraction of NO_(3)^(–)to PM_(2.5)under NH_(4)^(+)-rich conditions.Our findings imply that synchronous reduction in NO_(x)and NH_(3)emissions especially rural areas would be effective to mitigate NO_(3)^(–)-driven aerosol pollution. | Yangyang Zhang Aohan Tang Chen Wang Xin Ma Yunzhe Li Wen Xu Xiaoping Xia Aihua Zheng Wenqing Li Zengguo Fang Xiufen Zhao Xianlong Peng Yuping Zhang Jian Han Lijuan Zhang Jeffrey L.Collett Jr Xuejun Liu | 2022 | Journal of Environmental Sciences2022，34，12： | 2 |
| 4 | TSC1-mTOR-PLK轴以阶段特异性方式调节从施旺细胞增殖到髓鞘形成的内稳态开关显示文摘恰如其分的外周髓鞘形成取决于雪旺细胞增殖与分化进程间的平衡。丝氨酸/苏氨酸激酶(mTOR)整合多种环境因素,是细胞生长、代谢、发挥作用的中枢调节者。本文报道了一种mTOR的负性调节剂——结节性硬化复合体(TSC1),通过控制细胞增殖和髓鞘稳态,建立了雪旺细胞谱系进展和髓鞘形成的阶段依赖性程序。小鼠雪旺细胞祖细胞中TSC1的解离导致mTOR信号通路激活,继而导致雪旺细胞过量增殖,分化受阻,髓鞘形成减少。转录组分析显示,TSC1突变体中的mTOR活化使得polo样激酶(PLK)依赖性通路和细胞周期调节剂上调。弱化mTOR或者对PLK进行药理抑制部分挽救了因TSC1缺失导致的外周神经发育过程中的髓鞘形成减少。相较之下,成年小鼠成熟雪旺细胞中TSC1缺失可导致髓鞘的过度增殖和过度生长。本文的发现提示了TSC1-mTOR-PLK信号轴在控制雪旺细胞的发育过程中,从增殖到分化和髓鞘内稳态中起到的阶段特异性功能。 | Jiang M Rao R Wang J Wang J1 Xu L Wu LM Chan JR Wang H Lu QR 聂昊(编译) | 2018 | 神经损伤与功能重建2018，13，5： | 2 |
| 5 | Repairing of goat tibial bone defects with BMP-2 gene-modified tissue-engineered bone显示文摘 | Dai KR Xu XL Tang TT Zhu ZA Yu CF Lou JR Zhang XL | 2006 | 中国生物学文摘2006，20，5： | 2 |
| 6 | Rates of hippocampalat rophy correlate with change in clinical status in aging and AD显示文摘 | Jack CB Jr Petersen RC Xu Y | 2000 | Neuroloy2000，55，4： | 1 |
| 7 | MicroRNA-101, down-regulated in hepa-tocellular carcinoma, promotes apoptosis and suppresses tumorigenic-ity显示文摘 | Su H Yang JR Xu T | 2009 | Cancer Res2009，69，3： | 1 |
| 8 | Screening and cloning of multi-drug resistant genes in HL-60/MDR cells显示文摘 | Zheng GH Fu JR Xu YH | 2009 | Leuk Res2009，33，8： | 1 |
| 9 | Anatomic consideration of C2 pedicle screw placement显示文摘 | Ebraheim N Rollins JR Xu R | 1996 | Spine1996，21，6： | 1 |
| 10 | An anatomic consideration of C2 pedicle screw placement显示文摘 | Ebraheim N Rollins JR Xu R | 1996 | Spine1996，21，6： | 1 |
| 11 | Prostaglandin E2 suppresses lipopolysaccharide-stimulated IFN-beta production显示文摘 | Xu XJ Reichner JS Mastrofrancesco B Henry WL Jr Albina JE | 2008 | J Immunol2008，180，4： | 1 |
| 12 | Crystal structure of bovine coronavirus spike pro- tein lectin domain 显示文摘 | Peng G Xu L Lin YL Chen L Pasquarella JR Holmes KV Li F | 2012 | J Biol Chem2012，287，41： | 1 |
| 13 | Wavelet transform domain filters: a spatially selective noise filtration technique显示文摘 | Yansun Xu J 13 Weaver LI M Healy Jr el al | 1994 | IEEE Trans Image Processing1994，3，6： | 1 |
| 14 | Evidence for type Ⅱ cells as cells of origin of K-Ras-induced distal lung adenocarcinoma 显示文摘 | Xu X Rock JR Lu Y | 2012 | Proc Natl Acad Sci U S A2012，109，13： | 1 |
| 15 | Memory and MRI-based hippocampal volumes in aging and AD显示文摘 | Petersen RC Jack CR Jr Xu YC | 2000 | Neurology2000，54，： | 1 |
| 16 | Expressioon of matrix metalloproteinase(MMP)-2 and MMP-9 in human placenta and fetal membranes in re-lation to preterm and term labor显示文摘 | Xu P Alfaidy N Challis JR | 2002 | J Clin Endocrin Metab2002，87，3： | 1 |
| 17 | Rodent model of chronic central pain after spinal cord contusion injury and effects of gabapentin显示文摘 | Hulsebosch CE Xu GY Perez Polo JR | | 0，，： | 1 |
| 18 | Preoperative mediastinal and hilar nodal staging with diffusion-weighted magnetic res onance imaging and fluorodeoxyglucose positron emission tomography/computed tomography in patients with non small-cell lung cancer: which is better? 显示文摘 | Wu LM1 Xu JR Gu HY | 2012 | J Surg Res2012，178，1： | 1 |
| 19 | Indoor radon and lung cancer in China显示文摘 | BLOT W J XU Z Y BOICE J D Jr | 1990 | J Natl Cancer Inst1990，82，12： | 1 |
| 20 | Projection of the lumbar pedicle and its morphometric analysis显示文摘 | Ebraheim NA Rollins JR Xu R | 1996 | Spine1996，21，11： | 1 |
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