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| 1 | Enhanced grain refinement of Al-Si alloys by novel Al-V-B refiners显示文摘Al-V-B master alloy is promising for refining Al-Si alloys,yet its optimal composition with superior efficacy remains to be explored.In this work,the evolution of refining phases in the Al-10 Si/Al-V-B system with different V:B ratios was evaluated by thermodynamic calculations,based on which the Al-V-B refiners with V:B=1:1 and 5:1 were designed.Refining trails demonstrated that they could significantly reduce the grain size of Al-10 Si(wt.%)alloy from 1736 to 184-245μm with industrial addition amount.Detailed examinations results clarify that when V:B ratio is 1:1 the nucleation particle is(V,Al)B_(2),which has a VB_(2)-AlB_(2) core-shell structure and therefore presents the nucleation capability as AlB_(2) particle.When V:B ratio is as high as 5:1,the nucleation particle is pure VB_(2).Density functional theory(DFT)calculation indicates that(0001)VB_(2)/(111)α-Al interface has the lowest interfacial energy such that highest nucleation potency among other types of diboride/α-Al interfaces under consideration.The outcomes of this work provide fundamental guidance to develop superior V-B based refiners for Al-Si alloys. | Chenxi Zhao Yang Li Jin Xu Qun Luo Ying Jiang Qiling Xiao Qian Li | 2021 | Journal of Materials Science & Technology2021，，35： | 4 |
| 2 | Precise orbit determination for BDS satellites显示文摘Since the frst pair of BeiDou satellites was deployed in 2000,China has made continuous eforts to establish its own independent BeiDou Navigation Satellite System(BDS)to provide the regional radio determination satellite service as well as regional and global radio navigation satellite services,which rely on the high quality of orbit and clock products.This article summarizes the achievements in the precise orbit determination(POD)of BDS satellites in the past decade with the focus on observation and orbit dynamic models.First,the disclosed metadata of BDS satellites is presented and the contribution to BDS POD is addressed.The complete optical properties of the satellite bus as well as solar panels are derived based on the absorbed parameters as well the material properties.Secondly,the status and tracking capabilities of the L-band data from accessible ground networks are presented,while some low earth orbiter satellites with onboard BDS tracking capability are listed.The topological structure and measurement scheme of BDS Inter-Satellite-Link(ISL)data are described.After highlighting the progress on observation models as well as orbit perturbations for BDS,e.g.,phase center corrections,satellite attitude,and solar radiation pressure,diferent POD strategies used for BDS are summarized.In addition,the urgent requirement for error modeling of the ISL data is emphasized based on the analysis of the observation noises,and the incompatible characteristics of orbit and clock derived with L-band and ISL data are illuminated and discussed.The further researches on the improvement of phase center calibration and orbit dynamic models,the refnement of ISL observation models,and the potential contribution of BDS to the estimation of geodetic parameters based on L-band or ISL data are identifed.With this,it is promising that BDS can achieve better performance and provides vital contributions to the geodesy and navigation. | Qile Zhao Jing Guo Chen Wang Yifei Lyu Xiaolong Xu Chao Yang Junqiang Li | 2022 | Satellite Navigation2022，3，1： | 4 |
| 3 | Integration of semi-in vivo assays and multi-omics data reveals the effect of galloylated catechins on self-pollen tube inhibition in Camellia oleifera显示文摘Camellia oil extracted from the seeds of Camellia oleifera Abel.is a popular and high-quality edible oil,but its yield is limited by seed setting,which is mainly caused by self-incompatibility(SI).One of the obvious biological features of SI plants is the inhibition of self-pollen tubes;however,the underlying mechanism of this inhibition in C.oleifera is poorly understood.In this study,we constructed a semi-in vivo pollen tube growth test(SIV-PGT)system that can screen for substances that inhibit self-pollen tubes without interference from the genetic background.Combined with multi-omics analysis,the results revealed the important role of galloylated catechins in self-pollen tube inhibition,and a possible molecular regulatory network mediated by UDP-glycosyltransferase(UGT)and serine carboxypeptidase-like(SCPL)was proposed.In summary,galloylation of catechins and high levels of galloylated catechins are specifically involved in pollen tube inhibition under self-pollination rather than cross-pollination,which provides a new understanding of SI in C.oleifera.These results will contribute to sexual reproduction research on C.oleifera and provide theoretical support for improving Camellia oil yield in production. | Yihong Chang Wenfang Gong Jinming Xu Han Gong Qiling Song Shixin Xiao Deyi Yuan | 2023 | Horticulture Research2023，10，1： | 1 |
| 4 | d(GC)n repeats form Z-DNA within promoter region and repress the promoter activity in Escherichia coil显示文摘 | Shenghe Huang Chuxin Wu Dongming Li Haizhou Wang Zechang Rao Qiling Shen Chunxiang Chen Yong Liu Xun Xu Chengyu Hu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，7： | 1 |
| 5 | Enhanced ferro-/piezoelectric properties of tape-casting-derived Er^(3+)-doped Ba_(0.85)Ca_(0.15)Ti_(0.9)Zr_(0.1O3) optoelectronic thick films显示文摘Er^(3+)-doped Ba_(0.85)Ca_(0.15)Ti_(0.9)Zr_(0.1O3)(xEr-BCTZ,x=0,0.005,0.01,0.015)multifunctional thick films were prepared by the tape-casting method,using sol-gel-derived nano-sized powders as the matrix material.The surface morphologies,photoluminescence,and electrical properties were investigated.Dense microstructures with pure perovskite structure were obtained in the thick films.By doping an appropriate amount of Er^(3+),the samples exhibit superior up-conversion photoluminescence performance and simultaneously enhanced electrical performances.In addition,relatively higher texture fractions(with the largest value of 83.5%)were realized through introducing plate-like BaTiO_(3) templates to make the thick film grow by the[001]_(c) orientation.And the ferro-/piezoelectric properties of the thick films were further improved,showing potential in the applications of micro-optoelectronic devices. | Jie XU Qiling LU Jinfeng LIN Cong LIN Xinghua ZHENG Tengfei LIN Xiao WU | 2020 | Journal of Advanced Ceramics2020，9，6： | 1 |
| 6 | Self-targeting visualizable hyaluronate nanogel for synchronized intracellular release of doxorubicin and cisplatin in combating multidrug-resistant breast cancer显示文摘Multidrug-resistance(MDR)featuring complicated and poorly defined mechanisms is a major obstacle to the success of cancer chemotherapy in the clinic.Compound nanoparticles comprising multiple cytostatics with different mechanisms of action are commonly developed to tackle the multifaceted nature of clinical MDR.However,the different pharmacokinetics and release profiles of various drugs result in inconsistent drug internalization and suboptimal drug synergy at the tumor sites.In the present study,a type of self-targeting hyaluronate(HA)nanogels((CDDPH)^ANG/DOX)to reverse drug resistance through the synchronized pharmacokinetics,intratumoral distribution,and intracellular release of topoisomerase II inhibitor doxorubicin(DOX)and DNA-crosslinking agent cisplatin(CDDP)is developed.With prolonged circulation time and enhanced intratumoral accumulation in vivo,(CDDP)^HANG/DOX shows efficient drug delivery into the drug-resistant MCF-7/ADR breast cancer cells and enhanced antitumor activity.Besides,fluorescence imaging of DOX combined with the micro-computed tomography(micro-CT)imaging of CDDP facilitates the visualization of this combination tumor chemotherapy.With visualizable synchronized drug delivery,the self-targeting in situ crosslinked nanoplatform may hold good potential in future clinical therapy of advanced cancers. | Wen Ma Qiling Chen Weiguo Xu Meng Yu Yuanyuan Yang Binhua Zou Yu Shrike Zhang Jianxun Ding Zhiqiang Yu | 2021 | Nano Research2021，14，3： | 1 |
| 7 | Design of a novel mitochondria targetable turn-on fluorescence probe for hydrogen peroxide and its two-photon bioimaging applications显示文摘Considering that hydrogen peroxide(H2O2)plays significant roles in oxidative stress,the cellular signal transduction and essential biological process regulation,the detection and imaging of H2O2 in living systems undertakes critical responsibility.Herein,we have developed a novel two-photon fluorescence turn on probe,named as Pyp-B for mitochondria H2O2 detection in living systems.Selectivity studies show that probe Pyp-B exhibit highly sensitive response toward H2O2 than other reactive oxygen species(ROS)and reactive nitrogen species(RNS)as well as biologically relevant species.The fluorescence colocalization studies demonstrate that the probe can localize in the mitochondria solely.Furthermore,as a bio-compatibility molecule,the highly selective and sensitive of fluorescence probe Pyp-B have been confirmed by its cell imaging application of H2O2 in living A549 cells and zebrafishes under the physiological conditions. | Kangnan Wang Wen Ma Yuchun Xu Xin Liu Gui Chen Meng Yu Qiling Pan Chaobo Huang Xiaochuan Li Qingchun Mu Yongbing Sun Zhiqiang Yu | 2020 | Chinese Chemical Letters2020，31，12： | 1 |
| 8 | Control of Chemokine-Guided Cell Migration by Ligand Sequestration显示文摘 | Bijan Boldajipour Harsha Mahabaleshwar Elena Kardash Michal Reichman-Fried Heiko Blaser Sofia Minina Duncan Wilson Qiling Xu Erez Raz | 2008 | Cell2008，，3： | 1 |
| 9 | Clinical Observation on the Treatment of Diabetic Kidney Disease with Damp-heat Stasis Syndrome in Clinical Proteinuria Stage by Kunkui Kidney Preserving Paste显示文摘[Objectives]To evaluate the clinical efficacy and safety of Kunkui Kidney Preserving Paste in the treatment of diabetic kidney disease(DKD)patients with damp-heat stasis syndrome in the clinical proteinuria stage.[Methods]Retrospective analysis was made on 30 patients with DKD who were diagnosed with damp-heat stasis syndrome in the clinical proteinuria stage from March 2021 to March 2023 in Jiangsu Province Hospital of Chinese Medicine,and who took Kunkui Kidney Preserving Paste continuously for six months.The urinary albumin/creatinine ratio(UACR),urinary complement C3,and urea nitrogen(BUN)of DKD patients before and after treatment were compared,and estimated glomerular filtration rate(eGFR),blood creatinine(Scr),and cystatin C(CysC)were estimated,and the therapeutic effects on renal function and urinary protein were evaluated.[Results]After treatment,UACR significantly decreased(P<0.01),and urinary complement C3 and Scr decreased(P<0.05),while other indicators showed no significant statistical difference(P>0.05).In terms of evaluating the efficacy of urinary protein therapy,8 cases showed recent relief;8 cases showed significant effect;9 cases were effective,and 5 cases were invalid after treatment,with a total effective rate of 83.33%.In terms of renal function efficacy evaluation,8 cases showed significant effect;4 cases were effective;11 cases were stable,and 7 cases were invalid,with a total effective rate of 76.67%.In the safety evaluation,there were no obvious adverse reactions.[Conclusions]The Kunkui Kidney Preserving Past has significant clinical efficacy and safety in treating DKD patients with damp-heat stasis syndrome in the clinical proteinuria period.It has significant advantages in reducing urinary protein and protecting renal function,which is worthy of clinical promotion. | Ying TAN Qiling ZHANG Juan CHEN Xu YU Qianhua YAN Jiangyi YU | 2024 | Medicinal Plant2024，15，1： | 0 |
| 10 | New molecular connections in angiogenesis显示文摘 | Qiling Xu David Wilkinson | 2010 | Cell Research2010，20，9： | 0 |
| 11 | Design of cobalt-based catalysts with the uniformly distributed coreshell structure for ultra-efficient activation of peroxymonosulfate for tetracycline degradation显示文摘Catalysts that can rapidly degrade tetracycline(TC)in water without introducing secondary ion pollution have always been challenging.Herein,a cobalt-based catalyst(CoO_(x)@P-C)is prepared so that CoOx quantum particles(5e10 nm)are uniformly distributed on a linear substrate,and the outer layer is covered with a shell(P-C).The quantum particles of CoO_(x) provide many active sites for the reaction,which ensures the efficient degradation effect of the catalyst,and 30 mg/L TC can be completely degraded in only 5 min.The shell of the quantum particles'outer layer can effectively reduce ions'extravasation.The combination of the shell-like structure and the linear substrate greatly enhances the catalysis's stability and ensures that the catalyst is prepared into a film for practical application.The high catalytic activity of CoO_(x)@P-C is mainly due to the following factors:(1)Uniformly distributed ultra-small nanoparticles can provide many active sites.(2)The microenvironment formed by the core-shell structure enhances not only catalytic stability but also provides the driving force to improve the reaction rate.(3)The composite of CoO_(x) and P-C core-shell structure can accelerate electron transfer and generate many reactive oxygen species in a short time,which makes TC degrade extremely rapidly. | Hongjie Qin Weijie Zhang Qiling Zheng Penghui Zhang Shouwei Zhang Xijin Xu | 2023 | Journal of Materiomics2023，9，5： | 0 |
| 12 | Lanchester equation for cognitive domain using hesitant fuzzy linguistic terms sets显示文摘Intelligent wars can take place not only in the physical domain and information domain but also in the cognitive domain.The cognitive domain will become the key domain to win in the future intelligent war.A Lanchester equation considering cognitive domain is proposed to fit the development tendency intelligent wars in this paper.One party is considered to obtain the exponential enhancement advantage on combat forces in combat if it can gain an advantage in the cognitive domain over the other party according to the systemic advantage function.The operational effectiveness of the cognitive domain in war is considered to consist of a series of indicators.Hesitant fuzzy sets and linguistic term sets are powerful tools when evaluating indicators,hence the indicators are scored by experts using hesitant fuzzy linguistic terms sets here.A unique hesitant fuzzy hybrid arithmetical averaging operator is used to aggregate the evaluation. | HAN Qi LI Weimin XU Qiling ZHAO Minrui HUO Runze ZHANG Tao | 2022 | Journal of Systems Engineering and Electronics2022，33，3： | 0 |
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