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| 1 | Asiatic acid inhibits lung cancer cell growth in vitro and in vivo by destroying mitochondria显示文摘Asiatic acid(AA), a pentacyclic triterpene found in Centella asiatica, displays significant antiproliferative effects on cancer cells in vitro although the underlying mechanism of this effect remains unknown. This study investigated the efficacy and mechanism of action of AA against lung cancer both in vivo and in vitro. Using the MTT assay, AA was found to induce apoptosis in a dose- and timedependent manner, an effect enhanced by pretreatment with an autophagy inhibitor. It also elevated expression of microtubule-associated protein 1 light chain 3(LC3) and decreased the expression of p62.Furthermore, exposure to AA resulted in collapse of the mitochondrial membrane potential and generation of reactive oxygen species(ROS), suggesting mitochondria are the target of AA. In the mouse lung cancer xenograft model, oral administration of AA significantly inhibited tumor volume and weight accompanied by significant apoptosis of lung cancer cells. In addition, it led to a significant decrease in the expression of proliferating cell nuclear antigen(PCNA). In summary, the results show that AA significantly reduces lung cancer cell growth both in vitro and in vivo and that the associated apoptosis is mediated through mitochondrial damage. | Tiancong Wu Ji Geng Wenjie Guo Jing Gao Xixu Zhu | 2017 | Acta Pharmaceutica Sinica B2017，7，1： | 19 |
| 2 | Facile synthesis of hierarchical Na2Fe(SO4)2@rGO/C as high-voltage cathode for energy density-enhanced sodium-ion batteries显示文摘Fe-based sulfates are ideal cathode candidates for sodium-ion batteries(SIBs) owing to their high operating voltage and low cost but suffer from the nature of poor power performance. Herein, a hierarchical porous Na2Fe(SO4)2@reduced graphene oxide/carbon dot(Na2Fe(SO4)2@rGO/C) with low carbon content(4.12 wt%) was synthesized via a facile homogeneous strategy benefiting for engineering application,which delivers excellent sodium storage performance(high voltage plateau of 3.75 V, 85 m Ah g-1 and330 Wh kg-1 at 0.05 C;5805 W kg-1 at 10 C) and high Na+diffusion coefficient(1.19 × 10-12 cm2 s-1).Moreover, the midpoint voltage of assembled full cell could reach 3.0 V. The electron transfer and reaction kinetics are effectively boosted since the nanoscale Na2Fe(SO4)2 is supported by a robust crosslinked carbon matrix with rGO sheets and carbon dots. The slight rGO sheets sufficiently enhance the electron transfer like a current collecter and restrain the aggregation, as well as ensure smooth ion channels. Meanwhile, the carbon dots in the whole space connect with Na2Fe(SO4)2 and help rGO to promote the conductivity of the electrode. Ex-situ X-ray powder diffraction and X-ray photoelectron spectrometry analysis confirm the high reversibility of this sodiation/desodiation process. | Ge Yao Xixue Zhang Yongliang Yan Jiyu Zhang Keming Song Juan Shi Liwei Mi Jinyun Zheng Xiangming Feng Weihua Chen | 2020 | Journal of Energy Chemistry2020，29，11： | 3 |
| 3 | Combining oxygen plasma treatment with anchorage of cationized gelatin for enhancing cell affinity of poly(lactide-co-glycolide)显示文摘 | Shen Hong Hu Xixue Yang Fei | 2007 | Biomaterials2007，28，29： | 1 |
| 4 | The bioactivity of rhBMP--2 immobilized poly(lactide--co--glycolide) scaffolds显示文摘 | Shen Hong Hu Xixue Yang Fei | 2009 | Biomaterials2009，30，18： | 1 |
| 5 | An injectable scaffold:rhBMP--2--1oaded poly(lactide--co--glycolide)/ hydroxyapatite composite microspheres显示文摘 | Shen Hong Hu Xixue Yang Fei | 2010 | Acta biomaterialia2010，6，2： | 1 |
| 6 | Genome-wide profiling of circular RNAs,alternative splicing,and R-loops in stem-differentiating xylem of Populus trichocarpa显示文摘Circular RNAs(circRNAs)are a recently dis-covered type of non‐coding RNA derived from pre‐mRNAs.R‐loops consist of a DNA:RNA hybrid andthe associated single‐stranded DNA.InArabi-dopsis thaliana,circRNA:DNA R‐loops regulatealternative splicing(AS)ofSEPALLATA3(SEP3).However,the occurrence and functions ofcircRNAs and R‐loops inPopulus trichocarpaarelargely unexplored.Here,we performed circRNA‐enriched sequencing in the stem‐differentiatingxylem(SDX)ofP.trichocarpaand identified 2,742distinct circRNAs,including circ‐CESA4,circ‐IRX7,and circ‐GUX1,which are generated from genesinvolved in cellulose,and hemicellulose biosyn-thesis,respectively.To investigate the roles ofcircRNAs in modulating alternative splicing(AS),we detected 7,836 AS events using PacBio Iso‐Seq and identified 634 circRNAs that overlappedwith 699 AS events.Furthermore,using DNA:RNAhybrid immunoprecipitation followed by se-quencing(DRIP‐seq),we identified 8,932 R‐looppeaks that overlapped with 181 circRNAs and 672AS events.Notably,several SDX‐related circRNAsoverlapped with R‐loop peaks,pointing to theirpossible roles in modulating AS in SDX.Indeed,overexpressing circ‐IRX7increased the levels ofR‐loop structures and decreased the frequency ofintron retention in linearIRX7transcripts.Thisstudy provides a valuable R‐loop atlas resourceand uncovers the interplay between circRNAs andAS in SDX ofP.trichocarpa. | Xuqing Liu Yubang Gao Jiakai Liao Miao Miao Kai Chen Feihu Xi Wentao Wei Huihui Wang Yongsheng Wang XiXu Anireddy S.N.Reddy Lianfeng Gu | 2021 | Journal of Integrative Plant Biology2021，63，7： | 1 |
| 7 | EFFECT OF STRESS-INDUCED REACTIONS ON MORPHOLOGICAL STRUCTURE AND PROCESSABILITY OF PVC DURING PAN-MILLING显示文摘The effect of pan-milling on morphological structure, processability and properties of PVC was studied through SEM, FTIR, granulometer, GPC and mechanical properties test in the hope of gaining ease in operation, needless of plasticizers, a clean and efficient route for improving the processability of PVC through stress-induced reactions,fulfilling the idea of 'plasticizing PVC by itself'. The experimental results show that during pan-milling at ambient temperature, within 2-3 min, the microcrystalline structure of PVC becomes indistinct, the grain size of PVC is reduced from 130-160 μm to 1-50 μm the molecular weight of PVC is slightly decreased, the variation of molecular weight distribution is indistinct, the plasticizing time and torque at balance drop a great deal from 71-132 s to 31-33 s and from 18.2-22.1 Nm to 14.7-18.4 Nm, respectively, the processability of PVC is markedly improved, and the mechanical properties get enhanced too. | Hua-weiZou WenXu Qing-fenFeng XiXu | 2005 | Chinese Journal of Polymer Science2005，23，2： | 1 |
| 8 | A levitation force and magnetic field distribution measurement system in three dimensions 显示文摘 | Yang Wanmin Chao Xixu Shu Zhibing | 2006 | Physics2006，448，： | 1 |
| 9 | The immobilization of basic fibroblast growth factor on plasma-treated poly(lactide--co--glycolide)显示文摘 | Shen Hong Hu Xixue Bei Jianzhong | 2008 | Biomaterials2008，29，15： | 1 |
| 10 | Activity of plant flavonoids against antibiotic‐resistant bacteria显示文摘 | Hong‐XiXu Song F.Lee | 2001 | Phytother Res2001，，1： | 1 |
| 11 | Up-regulation of chloroplastic antioxidant capacity is involved in alleviation of nickel toxicity of Zea mays L. by exogenous salicylic acid显示文摘 | Haihua Wang Tao Feng Xixu Peng Mingli Yan Xinke Tang | 2009 | Ecotoxicology and Environmental Safety2009，，5： | 1 |
| 12 | Differential Expression of Rice Valine-Qlutamine Gene Family in Response to Nitric Oxide and Regulatory Circuit of OsVQ7 and OsWRKY24显示文摘The functional diversity of plant valine-qlutamine(VQ) proteins is closely associated with their partners WRKY transcription factors, and also with a complex network of signaling pathways that mediated by hormone molecules. We reported genome-wide expression profiles of differentially expressed rice VQ genes under nitric oxide(NO) treatment based on a microarray analysis. Cluster analysis of expression patterns revealed that some VQ genes and WRKY genes shared similar expression trends. Prediction of cis-elements showed that W-box or W-box-like sequences were overrepresented within the promoters of most of NO-responsive VQ genes. In particular, the similarly expressed Os VQ7 and Os WRKY24 showed great induction upon NO triggering. Transient expression assay and chromatin immunoprecipitation analysis demonstrated that OsWRKY24 was specifically bound to the promoter regions of Os VQ7 and Os WRKY24 itself, which contain multiple copies of W-box or W-box-like cis-elements. Yeast-two-hybrid assay indicated that OsWRKY24 can interact physically with OsVQ7 through the C-terminal of WRKY domain. The results suggested that OsVQ7 and OsWRKY24 may form an auto-and cross-regulation circuit that is required for tight regulation and fine-tuning of physiological processes they are involved in. These findings provided a solid foundation for exploring the specific functions of the VQ protein family in NO signaling pathway. | PENG Xixu XIAO Ting MENG Jiao TAO Zong ZHOU Dinggang TANG Xinke WANG Haihua | 2020 | Rice science2020，27，1： | 1 |
| 13 | Combining oxygen plasma treatment with anchorage of cationized gelatin for enhangcing cell affinity of poly ( lactide - co - glycolide) 显示文摘 | Hong Shen Xixue Hu Fei Yang | 2007 | Biomaterials2007，28，： | 1 |
| 14 | On data Integration,Warehousing and Software Reuse in the Construction of Digital Campus:A Review on Performance显示文摘 | Xixu Fu Kaijun Wu Xizhang Gong Linjun Xu | | 0，，15： | 1 |
| 15 | Identification and fine mapping of a fertility restorer gene for wild abortive cytoplasmic male sterility in the elite indica rice non-restorer line 9311显示文摘The wild abortive(WA)-type cytoplasmic male sterility(CMS)derived from the wild rice species Oryza rufipogon Griff.is used widely in three-line indica hybrids.The identification and mapping of restorer of fertility(Rf)genes aided in the development of WA-type hybrids.Here we report that testcross F1 plants from the WA-type CMS line and 9311 exhibited stainable pollen grains with no seed set,indicating that 9311 carries minor-effect Rfs for WA-type CMS.We developed an advanced backcross population consisting of plants harboring small regions of donor chromosomal segments from 9311 in the WATianfeng A genetic background with moderate seed setting rates.Genetic analysis showed that the pollen fertility levels of the backcross individuals are governed by a single gene from 9311 that we named Rf19(t).By use of the RICE 40 K gene chip,three introduced segments were identified in the fertile lines,and a candidate region spanning 4.37–8.29 Mb on chromosome 1 was identified for Rf19(t).Finally,Rf19(t)was fine-mapped to a region of 90 kb between the DNA marker loci STS1-163 and STS1-183,in which eight ORFs were predicted.Also,using relative expression analyses,comparative sequence analyses and functional domain analyses,we identified LOC_Os01g10530 as the most likely candidate gene for Rf19(t).Furthermore,Rf19(t)was found to function in fertility restoration,most probably by regulating the degradation of m RNA transcribed from the mitochondrial gene WA352.These results increase our knowledge of fertility restoration in WA-type CMS lines and will facilitate the development of high-quality pairs of WAtype CMS and maintainer lines. | Zuopeng Xu Yuanyue Du Xixu Li Ruixuan Wang Zhi'ai Chen Xiangqiang Zhao Qiaoquan Liu Shuzhu Tang Honggen Zhang | 2023 | The Crop Journal2023，11，3： | 0 |
| 16 | MECHANICAL PROPERTIES OF OZONIZED HDPE FILLED WITH SERICITE-TRIDYMITE-CRISTOBALITE显示文摘The mechanical properties of ozonized high density polyethylene (HDPE) blended with sericite-tridymitecristobalite (STC) were studied in this paper. The experimental results show that some oxygen containing polar groups are introduced on the molecular chain of HDPE through ozonization, the compatibility between HDPE and STC is thus improved, the mechanical properties of the blend are markedly enhanced. Compared with untreated HDPE/STC (60/40)blend, the yield strength and notched impact strength of ozonized HDPE/STC (60/40) blend are increased from 27.0 MPa to 29.5 MPa and from 2.8 kJ/m2 to 13.3 kJ/m2, respectively, the notched impact strength is close to that of HDPE (13.6 kJ/m2),the yield strength is in excess of 3.9 MPa of that of HDPE. The yield strength and notched impact strength will be further increased to 30.7 MPa and 32.4 kJ/m2 in case the ozonized HDPE is blended with STC pretreated with silane coupling agent. | MianZhou YiFu WenXu XiXu | 2005 | Chinese Journal of Polymer Science2005，23，1： | 0 |
| 17 | Study on the Characteristics and Efficient Cultivation Techniques of 'Rice-Rice-Potato' Triple Cropping Rotation Pattern显示文摘The efficient cultivation technique of 'rice-rice-potato' triple cropping rotation pattern is summarized by analyzing its characteristics and cultivation techniques in Yangjiang region of Guangdong Province,China,and machine-transplanted cultivation technique of double cropping rice and cultivation techniques of winter potato black film mulching are emphatically introduced,in order to promote the development of potato industry in Yangjiang City.The results will provide a scientific basis for the popularization and application of the 'rice-rice-potato' triple cropping rotation pattern. | Huang Xianliang Jiang Xianya Chen Maotuo Huang Riliang Tan Zhi Wu Shangxin Lu Xixu Yang Jianyuan | 2020 | Plant Diseases and Pests2020，11，4： | 0 |
| 18 | Layered K_(0.54)Mn_(0.78)Mg_(0.22)O_(2)as a high-performance cathode material for potassium-ion batteries显示文摘Layered Mn-based oxides are one of the promising cathode materials for potassium-ion batteries(KIBs)owing to their high theoretical capacities,abundant material supply,and simple synthesis method.However,the structural deterioration resulting from the Jahn-Teller effect of Mn ions hinders their further development in KIBs.Herein,a novel Mn-based layered oxide,K_(0.54)Mn_(0.78)Mg_(0.22)O_(2),is successfully designed and fabricated as KIBs cathode for the first time.It delivers smooth charging/discharging curves with high specific capacity of 132.4 mAh·g^(‒1)at 20 mA·g^(‒1)and good high-rate cycling stability with a capacity retention of 84%over 100 cycles at 200 mA·g^(‒1).Combining in-situ X-ray diffraction(XRD)and ex-situ X-ray photoelectron spectroscopy(XPS)analysis,the storage of K-ions by K_(0.54)Mn_(0.78)Mg_(0.22)O_(2)is revealed to be a solid-solution processes with reversible slip of the crystal lattice.The studies suggest that the rational doping of inactive Mg2+can effectively suppress the Jahn-Teller effect and provide outstanding structure stability.This work deepens the understanding of the structural evolution of Mn-based layered materials doped with inactive materials during de/potassiation processes. | Ruling Huang Qing Xue Jiao Lin XiXue Zhang Jiahui Zhou Feng Wu Li Li Renjie Chen | 2022 | Nano Research2022，15，4： | 0 |
| 19 | The Field Efficacy Trial of Several Fungicides for Controlling Rice Sheath Blight Disease (Rhizoctonia solani)显示文摘[Objective]The paper was to study the field fficacy of several fumgicide against rice sheath bligh(Rhicoetonia solm).[Method]Field efficacy trial was performed with three novel fungicides,75%tebuconazole.azxytrobin WG,75%tifloxystrobion-tebuconazole WG and 24%6 thi-fluzamide sC,while 30%difenoconazole-propiconazole EC and 10%jingangmyein AS,which had been Long circulated in production,were uwsed as contrl agents.[Result]The three novel fungicides had better control ffe on sheath blight than the control agents;75%tebuconazole.azoxys-trobin WG at the dase of 20 g/667 m2 received the best contrl efect,and the control efect was still 87.72%at 20 d post administration,and the yield increase efect was remarkable.The control efects of 75%tiloxystrobin-tebuconazole wG and 24%thifluzamide SC were 85.67%and 87.36%,repectively.[Conclusion]75%tebuconazole.azxoxystrobin wG,75%tifloxystrobin tebuconazole WC and 24%thiluamide SC could be promted as rotation fungicides to control rice sheath blight. | Huang Xianliang Jiang Xianya Chen Maotuo Huang Riliang Wu Shangxin Lu Xixu Yang Jianyuan | 2020 | Plant Diseases and Pests2020，11，3： | 0 |
| 20 | Study on Introduction Test of New Varieties of High Quality Conventional Rice in Yangjiang City, China显示文摘[Objective]The paper was to seek new varieties of high quality conventional rice suitable for Yangjiang area,Guangdong Province,China.[Method]In 2017,introduction test was performed with seven new varieties of high-quality conventional rice approved by Guangdong Province in recent years,including Huangsilizhan,Guangjingruanzhan,Heliyouzhan,Huahang 48,Limiaozhan,Lvyinzhan,Yuehesimiao,to investigate the main agronomic traits and yield of all varieties tested.[Result]The comprehensive performance of Lvyinzhan,Guangjingruanzhan,Limiaozhan and Huahang 48 was outstanding,showing the characters of good yield,excellent rice quality and strong stress resistance.[Conclusion]Lvyinzhan,Guangjingruanzhan,Limiaozhan and Huahang 48 are suitable for large-scale demonstration and promotion in Yangjiang area. | Jiang Xianya Lu Xixu Wu Shangxin Huang Riliang Huang Xianliang | 2020 | Plant Diseases and Pests2020，11，3： | 0 |
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