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| 1 | Heat transfer mechanism of the C/SiC ceramics pyramidal lattice compo- sites 显示文摘 | Wei Kai Cheng Xiangmeng He Rujie | 2014 | Composites Part B: Eng2014，63，： | 1 |
| 2 | Genetic polymorphism of wheat by IRAP analysis based on retrotransposon Wis2-1 A显示文摘 | Guo Xiangmeng Zheng Ling Ya Huiyuan | 2010 | Agricultural ScienceS*- Technology2010，11，8： | 1 |
| 3 | Ultra-high-temperature tensile properties and fracture behavior of ZrB 2 -based ceramics in air above 1500<ce:hsp sp='0.25'/>°C显示文摘 | Rubing Zhang Xiangmeng Cheng Daining Fang Liaoliang Ke Yuesheng Wang | 2013 | Materials and Design2013，，： | 1 |
| 4 | The outcome differences of CT screening for lung cancer pre and post following an algorithm in Zhuhai, China显示文摘 | Xueguo Liu Mingzhu Liang Yong Wang Kai Chen Xiangmeng Chen Peixin Qin Jianxing He Xianping Yi | 2010 | Lung Cancer2010，，2： | 1 |
| 5 | Heat trans- fer mechanism of the C/SiC eeramies pyramidal lattiee com- posites显示文摘 | WEI Kai CHENG Xiangmeng HE Rujie | 2014 | Composites :Part B2014，，63： | 1 |
| 6 | Ag--Cu-Zn alloy for brazing TiC cermet/steel 显示文摘 | Zhang Lixia Feng Jicai Zhang Baoyou Jing Xiangmeng | 2005 | Materials Letters2005，，59： | 1 |
| 7 | In vitro and in vivo characterization of erythrosin B and derivatives against Zika virus显示文摘Zika virus(ZIKV)causes significant human diseases without specific therapy.Previously we found erythrosin B,an FDA-approved food additive,inhibited viral NS2B−NS3 interactions,leading to inhibition of ZIKV infection in cell culture.In this study,we performed pharmacokinetic and in vivo studies to demonstrate the efficacy of erythrosin B against ZIKV in 3D mini-brain organoid and mouse models.Our results showed that erythrosin B is very effective in abolishing ZIKV replication in the 3D organoid model.Although pharmacokinetics studies indicated that erythrosin B had a low absorption profile,mice challenged by a lethal dose of ZIKV showed a significantly improved survival rate upon oral administration of erythrosin B,compared to vehicle control.Limited structure−activity relationship studies indicated that most analogs of erythrosin B with modifications on the xanthene ring led to loss or reduction of inhibitory activities towards viral NS2B−NS3 interactions,protease activity and antiviral efficacy.In contrast,introducing chlorine substitutions on the isobenzofuran ring led to slightly increased activities,suggesting that the isobenzofuran ring is well tolerated for modifications.Cytotoxicity studies indicated that all derivatives are nontoxic to human cells.Overall,our studies demonstrated erythrosin B is an effective antiviral against ZIKV both in vitro and in vivo. | Zhong Li Jimin Xu Yuekun Lang Xiangmeng Wu Saiyang Hu Subodh Kumar Samrat Anil M.Tharappel Lili Kuo David Butler Yongcheng Song Qing-Yu Zhang Jia Zhou Hongmin Li | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 0 |
| 8 | High-fidelity transfer of area-selective atomic layer deposition grown HfO_(2)through DNA origami-assisted nanolithography显示文摘DNA origami-assisted nanolithography(DOANL)for fabricating custom-designed nanomaterials through pattern transfer from DNA origami to different substrates materials are presented.However,the pattern's integrity and resolution face considerable challenges due to the uncontrollable growth of the nanomaterials during transformation and the unclear mechanism of DOANL.Herein,we report a DOANL combined with area-selective atomic layer deposition(ALD)strategy for fabricating custom shapes hafnium oxide(HfO2)with the high-fidelity and high-throughput.We find that the HfO_(2)selectively grows on DNA origami substrates in a hydroxyl-rich area instead of a methyl-rich protective layer.Combined with the merit of the area-selective ALD method,theHfO_(2)atom selectively coated on the DNA origami surface,thus,precisely modeling the shapes with high-precision in our study based on the surface groups difference of DNA origami and the naked hexamethyldisilane(HMDS)-treated substrates,which reveal the mechanical of high-fidelity pattern transfer based on DOANL.As a result,DNA origami structures can program the shape ofHfO_(2)nanostructures.The DOANL that is based on the principle of'bottom-up'precision assembly breaks through the shape complexity and high-throughput fabrication limitation of theHfO_(2)nanostructures,including two-and three-dimensional structures,plane and curved structures,monolithic and hollow structures.Based on the'top-down'accurate fabrication principle,the area-selective ALD on methyl-rich protective layer substrates improves the integrity and resolution of the pattern transfer process.Overall,this work provides a general technology for nanofabrication strategy. | Xiaowan Yuan Daiqin Xiao Wei Yao Zhihao Zhang Lin Yang Liyuan Zhang Yibo Zeng Jiaqi Liao Shanxiong Luo Chonghao Li Hong Chen Xiangmeng Qu | 2022 | Nano Research2022，15，6： | 0 |
| 9 | Design and Fabrication of Plasmonic Nanostructures with DNA for Surface-Enhanced Raman Spectroscopy Applications显示文摘Plasmonic nanostructures 显示唯一、强烈提高的光性质,因此为大量分光镜的应用保持大诺言,特别地提高表面的拉曼光谱学(重量的单位) 。对重量的单位的主要贡献从在光领域强烈地由于局部性的表面电浆子刺激被集中的 nanojunctions 放的分子产生,这很好被承认。在重量的单位的关键挑战之一因此与可控制的 nanojunctions 躺在 plasmonic nanostructures 的设计和制造。在最近的年里,由利用无匹的基础配对的自我识别性质,调停 DNA 的汇编与明确的几何学和拓扑学为复杂、层次的 plasmonic nanostructures 的精确构造作为一个强大、可编程的工具出现了。在这评论,我们将由 DNA 纳米技术的优点在 plasmonic nanostructures 的一个富有的变化的设计和制造上总结最近的进展,并且在重量的单位象应用一样讨论他们的光性质。 | Chunbo Leng Cheng Wang Huixin Xiu Xiangmeng Qu Lizhen Chen Qian Tang Li Li | 2016 | Chinese Journal of Chemistry2016，34，3： | 0 |
| 10 | Delivery of therapeutic oligonucleotides in nanoscale显示文摘Therapeutic oligonucleotides(TOs)represent one of the most promising drug candidates in the targeted cancer treatment due to their high specificity and capability of modulating cellular pathways that are not readily druggable.However,efficiently delivering of TOs to cancer cellular targets is still the biggest challenge in promoting their clinical translations.Emerging as a significant drug delivery vector,nanoparticles(NPs)can not only protect TOs from nuclease degradation and enhance their tumor accumulation,but also can improve the cell uptake efficiency of TOs as well as the following endosomal escape to increase the therapeutic index.Furthermore,targeted and on-demand drug release of TOs can also be approached to minimize the risk of toxicity towards normal tissues using stimuli-responsive NPs.In the past decades,remarkable progresses have been made on the TOs delivery based on various NPs with specific purposes.In this review,we will first give a brief introduction on the basis of TOs as well as the action mechanisms of several typical TOs,and then describe the obstacles that prevent the clinical translation of TOs,followed by a comprehensive overview of the recent progresses on TOs delivery based on several various types of nanocarriers containing lipid-based nanoparticles,polymeric nanoparticles,gold nanoparticles,porous nanoparticles,DNA/RNA nanoassembly,extracellular vesicles,and imaging-guided drug delivery nanoparticles. | Lei Wu Wenhui Zhou Lihua Lin Anhong Chen Jing Feng Xiangmeng Qu Hongbo Zhang Jun Yue | 2022 | Bioactive Materials2022，7，1： | 0 |
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