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| 1 | A simplified index to assess the combined impact of tropical cyclone precipitation and wind on China显示文摘Relationships between tropical cyclone(TC)precipitation,wind,and storm damage are analyzed for China based on TCs over the period from 1984 to 2013.The analysis shows that the maximum daily areal precipitation from stations with daily precipitation of ≥50 mm and the sum of wind gusts of ≥13.9 m/s can be used to estimate the main damage caused by TCs,and an index combining the precipitation and wind gust of a TC(IPWT)is defined to assess the severity of the combined impact of precipitation and wind.The correlation coefficient between IPWT and the damage index for affecting TCs is 0.80,which is higher than that for only precipitation or wind.All TCs with precipitation and wind affecting China are divided intofive categories,Category 0 to Category 4,based on IPWT,where higher categories refer to higher combined impacts of precipitation and wind.The combined impact category is closely related to damage category and it can be used to estimate the potential damage category in operational work.There are 87.7%,72.9%,69.8%,and 73.4%of cases that have the same or one category difference between damage category and combined impact category for Categories 1,2,3,and 4,respectively.IPWT and its classification can be used to assess the severity of the TC impact and of combined precipitation and wind conveniently and accurately,and the potential damage caused by TCs.The result will be a good supplementary data for TC intensity,precipitation,wind,and damage.In addition,IPWT can be used as an index to judge the reliability of damage data.Further analysis of the annual frequency of combined precipitation-wind impact categories reveals no significant increasing or decreasing trend in impact over China over the past 30 years. | Peiyan CHEN Hui YU Ming XU Xiaotu LEI Feng ZENG | 2019 | Frontiers of Earth Science2019，13，4： | 9 |
| 2 | INTRODUCTION AND APPILICATION OF A NEW COMPREHENSIVE ASSESSMENT INDEX FOR DAMAGE CAUSED BY TROPICAL CYCLONES显示文摘Using principal component analysis,a new comprehensive assessment index for damage caused by tropical cyclones in China's Mainland is developed based on data from 1984 to 2008.it is a weighted average of four kinds of damage data:including the deaths and missing,affected crop area,destroyed houses,and rate of direct economic loss.The weighting coefficients are set by principal component analysis.Two indices are derived,which differ in the importance of the deaths and missing in severity assessment according to the sign of the second principal component of damage data.Trends in the damage caused by individual tropical cyclones and in the annual frequencies of the various levels of severity of damage caused by tropical cyclones are analyzed.no clear trend in damage from individual tropical cyclones is found.The annual frequency of tropical cyclones causing heavy and catastrophic damage shows a clear decrease from 1984 to 2008 with no trend in the total number of damaging tropical cyclones. | Peiyan Chen Xiaotu Lei Ming Ying | 2013 | Tropical Cyclone Research and Review2013，2，3： | 7 |
| 3 | Role of ENSO in the interannual relationship between Tibetan Plateau winter snow cover and Northwest Pacific tropical cyclone genesis frequency显示文摘Previous studies have revealed a significantly negative correlation between prior winter snow cover over the Tibetan Plateau(TPSC) and tropical cyclone genesis frequency(TCF) over the western North Pacific(WNP) in the following typhoon season. This study revisited this relationship based on long-term observational data. The results showed that the interannual correlation between TCF over the WNP and TPSC experienced a shift in the early 1990 s. This correlation is significant during only 1993–2012 and is considerably weak during 1976–1992. The possible reasons causing the shift were examined further, and the results demonstrated that the central Pacific(CP) El Ni?o-Southern Oscillation(ENSO) has played a vital role in intensifying the interannual relationship between TCF over the WNP and TPSC since the early 1990 s. During 1993–2012, TPSC was negatively related to CP ENSO. When TPSC was higher than(lower than) normal, CP ENSO was often in its cold(warm) phase. Such a combination remarkably enhances the relationship of TPSC with the zonal land-sea thermal difference and thus with the summer monsoon over the WNP. Additionally, it enhances the modulation of TPSC on the dynamical environments controlling TCF. As a result, the linkage between TPSC and TCF was significantly strengthened in this period. In sharp contrast, due to the weak relationship between TPSC and ENSO followed by the weak modulation of TPSC on the summer monsoon over the WNP and the dynamical environment during 1976–1992, the linkage between TPSC and TCF was weak during this time period. The results from additional dynamical diagnostic analyses further showed that during 1993–2012 CP ENSO modulated the barotropic energy conversion of zonal winds over the WNP, contributing to the intensified relationship between TPSC and TCF. These results will improve seasonal forecasting of tropical cyclone activity over the WNP. | ZHAN RuiFen DING YiHui WU LiGuang LEI XiaoTu | 2016 | Science China Earth Sciences2016，59，10： | 6 |
| 4 | Characteristics of carbonyls and volatile organic compounds (VOCs) in residences in Beijing, China显示文摘不稳定的有机化合物(VOC ) 和羰基混合物在 50 个住处在室内并且在户外被测量在加热的北京(2011 年 12 月) 和非加热的季节(4 月 /5 月, 2012 ) 。为 VOC 的 SUMMA 罐和为羰基混合物的散开的刺绣花样在每个地点为 24 h 被部署,并且 94 混合物被确定。甲醛,丙酮和乙醛与是的室内的中部的集中在室内并且在户外是最丰富的羰基混合物 32.1, 21.7 和 15.3 g ?? | Hengyi DUAN Xiaotu LIU Meilin YAN Yatao WU Zhaorong LIU | 2016 | Frontiers of Environmental Science & Engineering2016，10，1： | 3 |
| 5 | Improving the Extreme Rainfall Forecast of Typhoon Morakot(2009) by Assimilating Radar Data from Taiwan Island and China's Mainland显示文摘This study examined the impact of an improved initial field through assimilating ground-based radar data from China's Mainland and Taiwan Island to simulate the long-lasting and extreme rainfall caused by Morakot(2009). The vortex location and the subsequent track analyzed through the radial velocity data assimilation(VDA) are generally consistent with the best track. The initial humidity within the radar detecting region and Morakot's northward translation speed can be significantly improved by the radar reflectivity data assimilation(ZDA). As a result, the heavy rainfall on both sides of Taiwan Strait can be reproduced with the joint application of VDA and ZDA. Based on sensitivity experiments, it was found that, without ZDA, the simulated storm underwent an unrealistic inward contraction after 12-h integration, due to underestimation of humidity in the global reanalysis, leading to underestimation of rainfall amount and coverage. Without the vortex relocation via VDA, the moister(drier) initial field with(without) ZDA will produce a more southward(northward) track, so that the rainfall location on both sides of Taiwan Strait will be affected. It was further found that the improvement in the humidity field of Morakot is mainly due to assimilation of high-value reflectivity(strong convection) observed by the radars in Taiwan Island, especially at Kenting station. By analysis of parcel trajectories and calculation of water vapor flux divergence, it was also found that the improved typhoon circulation through assimilating radar data can draw more water vapor from the environment during the subsequent simulation, eventually contributing to the extreme rainfall on both sides of Taiwan Strait. | Xuwei BAO Dan WU Xiaotu LEI Leiming MA Dongliang WANG Kun ZHAO Ben Jong-Dao JOU | 2017 | Journal of Meteorological Research2017，31，4： | 3 |
| 6 | WMO TYPHOON LANDFALL FORECAST DEMONSTRATION PROJECT(WMO-TLFDP) PROGRESS AND FUTURE PLANS显示文摘The 'WMO Typhoon Landfall Forecast Demonstration Project(TLFDP)' was started in May 2010 in conjunction with the start of the Shanghai World Expo 2010. The project was successful in terms of assisting the local forecasters in providing an efficient tropical cyclone(TC) forecast service for World Expo 2010, demonstrating the performance of the most up-to-date techniques in TC forecasting, and enhancing the ability of forecasters to effectively use products based on advanced TC forecasting techniques. The first phase was completed in December 2012 and the second phase was completed in December 2015. The third phase(TLFDP-III) started in 2016.During its first(2010-2012) and second(2013-2015) phases, TLFDP collected real-time TC forecast products from 15 Typhoon Forecast Product Providers(TFPPs). The products include deterministic track and intensity forecasts, ensemble track and intensity forecasts, deterministic wind radii forecasts, wind probability forecasts, and gridded model outputs. The products were disseminated through the project's website and the operational website of the Shanghai Typhoon Warning Center.TLFDP has made significant progress in TC forecast verification, including setting up the tools for both realtime and post-season TC forecast verification, developing and integrating several new verification techniques, carrying out a survey on the operational status of TC forecast verification in the western North Pacific region, and contributing to the WMO document 'Verification of tropical cyclone forecasts'. The post-season forecast verification was reported to the Session of the UNESCAP/WMO Typhoon Committee since 2013. New consensus methods for TC track and intensity forecasts were also proposed either based on Ensemble Prediction Systems(EPSs) products or multiple deterministic NWP model products. Two training workshops on TC forecasting were organized by the TLFDP and held in Shanghai, China, in May 2010 and June 2012, respectively, and seven research fellowship projects were implemented as jointly supported by the UNESCAP/WMO Typhoon Committee, Shanghai Typhoon Institute and Hong Kong Observatory.In its third phase(TLFDP-III, 2016-2018), the project will continue its effort on demonstration and evaluation of the newly developed forecasting techniques for TCs, and developing and documenting advanced guidance for the verification of TC forecasts, with special attention to TC intensity and precipitation. | Xiaotu Lei Hui Yu Guomin Chen Barbara Brown Sai Tick Chan Ajit Tyagi | 2016 | Tropical Cyclone Research and Review2016，5，3： | 2 |
| 7 | OVERVIEW ON THE PROGRESS OF WORKING GROUP ON METEOROLOGY OF ESCAP/WMO TYPHOON COMMITTEE IN THE RECENT 10 YEARS显示文摘This paper reviews the major achievements of the Working Group on Meteorology(WGM) of ESCAP/WMO Typhoon Committee since its establishment in 2004, especially in tropical cyclone observational research and scientific experiments, tropical cyclone monitoring and forecasting technologies, seasonal prediction and climate change assessment for the past decade. The progress illustrates the great value of the Committee and WGM in monitoring and forecasting of tropical cyclones in the region and the improvement of disaster prevention and reduction capabilities. | XIAOTU LEI CLARENCE FONG VICENTE B MALANO CHE GAYAH ISMAIL | 2019 | Tropical Cyclone Research and Review2019，8，2： | 2 |
| 8 | A METHODOLOGICAL STUDY ON AMH COPULA-BASED JOINT EXCEEDANCE PROBABILITIES AND APPLICATIONS FOR ASSESSING TROPICAL CYCLONE IMPACTS AND DISASTER RISKS(PART Ⅰ)显示文摘A disaster induced by a tropical cyclone(TC)is a complex non-linear process,involving interactions of multiple factors.Assuming that the resilience to TC disasters remains basically unchanged,the disaster-causing risk is usually consistent with intensities of the TC-induced rainstorms and wind.When an area is hit by a low probability TC,the rainstorm and wind intensities are higher,and the likelihood for causing a disaster is greater.Therefore,criteria for the impact of a TC and disaster risk assessments can be established based on the probable intensities of the TC-associated rainstorms and wind.In this study,an AMH Copula-based function is introduced to investigate the joint risk probabilities of TC rainstorms and wind.In line with the equivalence principle of the distribution of a stochastic atmospheric phenomenon in both time and space,and taking the impact on Shanghai of TC Haikui as an example,the Copula-based joint probability distribution model is developed to assess the impacts of TC rainstorms and wind,based on the marginal distributions of the maximum daily rainfall and extreme gust velocity.The joint exceedance probabilities of TC rainstorms and wind derived from the model can be used as criteria to measure the risk levels.As our findings show,this approach captures the TC risks well,especially in high-risk areas.The aim of the study is to provide a practically useful concept for making more accurate assessments of the risk level of an extreme weather event using observational data,and objective criteria for risk avoidance and transfer. | QIUZHEN YANG MING XU XIAOTU LEI XIAO ZHOU XIAOQIN LU | 2014 | Tropical Cyclone Research and Review2014，3，1： | 2 |
| 9 | A CHALLENGE OF THE EXPERIMENT ON TYPHOON INTENSITY CHANGE IN COASTAL AREA显示文摘The Experiment on Typhoon Intensity Change in Coastal Area(EXOTICCA) was proposed by the China Meteorological Administration(CMA) and Hong Kong Observatory(HKO) and endorsed by the ESCAP/WMO Typhoon Committee(TC). The major goals and objectives of the EXOTICCA are: 1) to conduct the field campaigns on the intensity and structural characteristics of the target offshore and landfall tropical cyclones by employing integrated and novel observation techniques, and 2) to conduct demonstration research on the utilization of the synergized field observation data with the aim of deepening the understanding of the mechanism of structure and intensity changes, to improve the relevant capability of operational analysis, numerical weather prediction(NWP) models forecast, reliable storm surge and flooding and associated risk assessment. The Organizational structure and implementation schedule etc. are also introduced in this paper. | XIAOTU LEI WAIKIN WONG CLARENCE FONG | 2017 | Tropical Cyclone Research and Review2017，6，3： | 2 |
| 10 | Personalized cancer vaccines from bacteria-derived outer membrane vesicles with antibody-mediated persistent uptake by dendritic cells显示文摘Nanocarriers with intrinsic immune adjuvant properties can activate the innate immune system while delivering tumor antigen,thus efficiently facilitating antitumor adaptive immunity.Bacteria-derived outer membrane vesicles(OMVs)are an excellent candidate due to their abundance of pathogen associated molecular patterns.However,during the uptake of OMVs by dendritic cells(DCs),the interaction between lipopolysaccharide and toll-like receptor 4 induces rapid DC maturation and uptake blockage,a phenomenon we refer to as“maturation-induced uptake obstruction'(MUO).Herein we decorated OMV with the DC-targeting aDEC205 antibody(OMV-DEC),which endowed the nanovaccine with an uptake mechanism termed as 4 | Jie Liang Keman Cheng Yao Li Jiaqi Xu Yiwei Chen Nana Ma Qingqing Feng Fei Zhu Xiaotu Ma Tianjiao Zhang Yale Yue Guangna Liu Xinjing Guo Zhiqiang Chen Xinwei Wang Ruifang Zhao Ying Zhao Jian Shi Xiao Zhao Guangjun Nie | 2022 | Fundamental Research2022，2，1： | 2 |
| 11 | Overview of the development history of China’s typhoon research and operational work in the past century显示文摘Because typhoons are one of the most major natural disasters in the southeastern coastal areas of China,great attention has been paid to the prevention and mitigation of the disasters caused by typhoons.Over the past century,significant progress has been made in typhoon-related scientific research and operational work in China,including the construction of a network of typhoon monitoring stations,the establishment of forecasting operation systems,early warning and prevention of typhoon-related disasters,and the research of basic theories of typhoon behaviors and key forecasting technologies.This paper briefly reviews the milestones in the development history of typhoon research in China over the past century and a half in order to commemorate the predecessors,especially those who made historical contributions to the advancement of typhoon research since the economic and cultural reforms known as the'Opening of China',who provided historical references which enabled China to become an international leader in the field of typhoon science and technology. | Xiaotu LEI | 2020 | Science China Earth Sciences2020，63，3： | 1 |
| 12 | Simulation of fully nonlinear 3-D numerical wave tank显示文摘 | Zhang Xiaotu Teng Bin Ning Dezhi | 2004 | China Ocean Engineering2004，18，： | 1 |
| 13 | DNA methylation data analysis and its application to cancer research显示文摘 | Xiaotu Ma Yi-Wei Wang Michael Q Zhang Adi F Gazdar | 2013 | Epigenomics2013，，3： | 1 |
| 14 | CDKN2A/p16 Inactivation Mechanisms and Their Relationship to Smoke Exposure and Molecular Features in Non–Small-Cell Lung Cancer显示文摘 | Kit W. Tam Wei Zhang Junichi Soh Victor Stastny Min Chen Han Sun Kelsie Thu Jonathan J. Rios Chenchen Yang Crystal N. Marconett Suhaida. A. Selamat Ite A. Laird-Offringa Ayumu Taguchi Samir Hanash David Shames Xiaotu Ma Michael Q. Zhang Wan L. Lam Adi Gaz | 2013 | Journal of Thoracic Oncology2013，，11： | 1 |
| 15 | A pilot investigation on oxidation of ammonium sulfite by streamer corona plasma 显示文摘 | Xiaotu Hu Tianle Zhu Xuedong Jiang | 2008 | Chemical Engineering Journal2008，139，： | 1 |
| 16 | Preliminary research on the inner core and outer size of tropical cyclones and its relationship with the intensity of tropical cyclones显示文摘 | Wu Lianyao Lei Xiaotu | 2014 | J Trop Meteorol2014，20，4： | 1 |
| 17 | Applications of probability and statistics in cancer genomics显示文摘Background:The past decade has witnessed a rapid progress in our understanding of the genetics of cancer and its progression.Probabilistic and statistical modeling played a pivotal role in the discovery of general patterns from cancer genomics datasets and continue to be of central importance for personalized medicine.Results:In this review we introduce cancer genomics from a probabilistic and statistical perspective.We start from(1)functional classification of genes into oncogenes and tumor suppressor genes,then(2)demonstrate the importance of comprehensive analysis of different mutation types for individual cancer genomes,followed by(3)tumor purity analysis,which in turn leads to(4)the concept of ploidy and clonality,that is next connected to(5)tumor evolution under treatment pressure,which yields insights into cancer drug resistance.We also discuss future challenges including the non-coding genomic regions,integrative analysis of genomics and epigenomics,as well as early cancer detection.Conclusion:We believe probabilistic and statistical modeling will continue to play important roles for novel discoveries in the field o f cancer genomics and personalized medicine. | Xiaotu Ma Sasi Arunachalam Yanling Liu | 2020 | Quantitative Biology2020，8，2： | 0 |
| 18 | Efficacy and safety of Chinese herbal medicine as adjunctive therapy in sepsis patients with bloodstream infection:a propensity-matched analysis显示文摘OBJECTIVE:To investigate the efficacy and safety of Chinese herbal medicine in treating sepsis patients with bloodstream infection.METHODS:A 6-year retrospective study was carried out at a university hospital in China.Adult sepsis patients with bloodstream infection were included.The primary outcome was 28-day mortality after admission.Propensity score method was used to adjust for possible confounding.28-day mortality was estimated by KaplanMeier analysis and compared using the log-rank test.Cox regression analysis was carried out to identify factors impacting in-hospital mortality outcomes.RESULTS:Following the application of the propensity score method,a total of 176 patients were included.The all-cause 28-day mortality in the control group and Chinese herbal medicine group was 21.6%and 14.8%,respectively.Kaplan-Meier survival analysis showed that Chinese herbal medicine was associated with a lower hazard ratio(HR)in all-cause 28-day death compared with the control group[HR=0.44,95%CI(0.22,0.90),P<0.05].The complications were similar between the two groups(P>0.05).Blood-activating and stasis-eliminating herb administration was associated with reduced inhospital mortality among sepsis patients with bloodstream infection[HR=0.54,95%CI(0.34,0.94),P<0.05].CONCLUSIONS:Chinese herbal medicine,especially the blood-activating and stasis-eliminating herb,might have certain efficacy and safety in treating sepsis patients with bloodstream infection.Clinicians should prescribe blood-activating and stasis-eliminating herb in treating these two coalescent critical diseases as long as no contraindications exist.However,further studies are needed to validate our results. | ZHOU Xianshi ZHONG Minlin XI Xiaotu LI Jun TANG Guanghua | 2024 | Journal of Traditional Chinese Medicine2024，44，1： | 0 |
| 19 | SUMMARY OF RETIRED TYPHOONS IN THE WESTERN NORTH PACIFIC OCEAN显示文摘Names have been given to tropical cyclones which raging through the western North Pacific Ocean since 1947.However,considering the disastrous impact or some extreme uniqueness quite a few typhoons have their names retired from the list.This study conducts preliminary analysis and summarizes the frequency,impact and also explains why they were retired.It shows that a total of 31 typhoons(in the western North Pacific Ocean)have been removed from the list from 1947 on,most of which retired after 2000 amounting to 20 as against 11 before 2000.Collectively,these retired typhoons have made 16843 people killed or missing and caused a heavy property loss of$45.7 billion,averaging 543 fatalities and property loss of$1.69 billion each(capping at 8000 and$10 billion respectively).Most typhoons were retired due to huge personnel and property loss.However,some others were removed for their unique feature such as developed near equator,extremely long typhoon tracks,etc.Moreover,there were some retired due to neither of the above reasons.In this connection,the study also discusses the standard of retiring typhoons. | LEI XIAOTU ZHOU XIAO | 2012 | Tropical Cyclone Research and Review2012，1，1： | 0 |
| 20 | WMO TYPHOON LANDFALL FORECAST DEMONSTRATION PROJECT(WMO-TLFDP)——CONCEPT AND PROGRESSES显示文摘The World Expo 2010 was successfully held in Shanghai from May to October 2010. Activities related to the Expo were spread out in the Eastern China. To provide a better typhoon landfall forecast service for the Expo and to demonstrate the most advanced typhoon forecast techniques in the world, the “WMO Typhoon Landfall Forecast Demonstration Project(WMO-TLFDP)” began in May 2010 and will end in December 2012. It is a component of the Shanghai Multi-Hazard Early Warning System Project. Significant progresses have been made. First, the WMO-TLFDP Training Workshop on Tropical Cyclone Forecasting was held successfully in Shanghai, China during 24-28 May, 2010. Second. a total of 13 typhoon forecast product providers have participated in the project by providing real-time forecast products. Third, typhoon track, intensity and rainfall forecasts are verified in both real time and post season manners. Fourth, products of the project are disseminated through the project’s website(http://gffzz51e5262901944538hp9ubv0xqqp0o60uk.ffgz.tsg.suse.edu.cn) and the operational website of the Shanghai Typhoon Warning Center. Finally, all the data and products of named tropical cyclones since May 2010 are archived by the Regional Meteorological Center of Eastern China, which are available to research, training and capacity-building activities. It is demonstrated that current operational models are valuable in providing guidance to the forecast of not only track, but also intensity and heavy rainfall of tropical cyclones. Consensus techniques and ensemble prediction systems are promising in assisting the forecasters and decision makers to provide better tropical cyclone forecast and warning service. The WMO-TLFDP has supported effectively the forecasters and typhoon-related weather services during the World EXPO 2010, and it will continue to promote the implementation of the most advanced typhoon forecast techniques among the members of ESCAP/WMO Typhoon Committee, which ultimately will be of benefit to other WMO Members as well. | XU TANG LEI XIAOTU YU HUI | 2012 | Tropical Cyclone Research and Review2012，1，1： | 0 |
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