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| 1 | Start-up of the anammox process from the conventional activated sludge in a hybrid bioreactor显示文摘The anaerobic ammonium oxidation (anammox) process was successfully started up from conventional activated sludge using a hybrid bioreactor within 2 months.The average removal efficiencies of ammonia and nitrite were both over 80%,and the maximum total nitrogen removal rate of 1.85 kg N/(m 3 ·day) was obtained on day 362 with the initial sludge concentration of 0.7 g mixed liquor suspended solids (MLSS)/L.Scanning electron microscope (SEM) observation of the granular sludge in the hybrid reactor clearly showed a high degree of compactness and cell sphericity,and the cell size was quite uniform.Transmission electron microscope photos showed that cells were round or oval,the cellular diameter was 0.6-1.0 μm,and the percentage of the anammoxosome compartment was 51%-85% of the whole cell volume.Fluorescence in situ hybridization analysis (FISH) indicated that anammox bacteria became the dominant population in the community (accounting for more than 51% of total bacteria on day 250).Seven planctomycete 16S rRNA gene sequences were present in the 16S rRNA gene clone library generated from the biomass and affiliated to Candidatus Kuenenia stuttgartiensis and Candidatus Brocadia sp.,a new anammox species.In addition,the average effluent suspended solid (MLSS) concentrations of outlets I (above the non-woven carrier) and II (below the non-woven carrier) were 0.0009 and 0.0035 g/L,respectively.This showed that the non-woven carrier could catch the biomass effectively,which increased biomass and improved the nitrogen removal rate in the reactor. | Xiumei Duan Jiti Zhou Sen Qiao Xin Yin Tian Tian Fangdi Xu | 2012 | Journal of Environmental Sciences2012，24，6： | 3 |
| 2 | Effects of phosphorus concentration on Cr(VI) sorption onto phosphorus-rich sludge biochar显示文摘在 Cr (VI ) 吸着上调查磷内容的效果到充满磷的 biochar 上,从 4 ~ 60 mg 的不同的磷集中的污水污泥? | Wenchuan DING Wenlong PENG Xiaolan ZENG Xiumei TIAN | 2014 | Frontiers of Environmental Science & Engineering2014，8，3： | 2 |
| 3 | Novel single-stage autotrophic nitrogen removal via co-immobilizing partial nitrifying and anammox biomass 显示文摘 | Sen Qiao Tian Tian Xiumei Duan | 2013 | Chemical Engineering Journal2013，230，： | 1 |
| 4 | Antiviral Treatment Alters the Frequency of Activating and Inhibitory Receptor-Expressing Natural Killer Cells in Chronic Hepatitis B Virus Infected Patients显示文摘 | Juan Lv Qinglong Jin Haibo Sun Xiumei Chi Xiaoli Hu Hongqing Yan Yu Pan Weihua Xiao Zhigang Tian Jinlin Hou Damo Xu Zhengkun Tu Junqi Niu Alex Kleinjan | 2012 | Mediators of Inflammation2012，，： | 1 |
| 5 | Sinterability of Zirconia Top Coat of Investment Mold for Ti Alloy显示文摘In this paper. zirconia is used as top mold material for Ti investment casting. Top mold samples are made by proper mold building technology. The effect of different sintering temperature on chemical composition, microstructure and residual bending strength of the top mold sample is Studied. The volume and homogeneity of the air holes in the top mold are determined by sintering temperature. and finally determined the residual bending strength of the mold sample was determined. | Yuyong CHEN Xiumei QI Xuezhu MA Huiguang WANG and Jing TIAN School of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001, China | 2001 | Journal of Materials Science & Technology2001，17，1： | 1 |
| 6 | YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma显示文摘Background:Y-box binding protein 1(YB1 or YBX1)plays a critical role in tumorigenesis and cancer progression.However,whether YB1 affects malignant transformation by modulating non-codingRNAs remains largely unknown.This study aimed to investigate the relationship between YB1 and microRNAs and reveal the underlying mechanism by which YB1 impacts on tumor malignancy via miRNAs-mediated regulatory network.Methods:The biological functions of YB1 in hepatocellular carcinoma(HCC)cells were investigated by cell proliferation,wound healing,and transwell invasion assays.The miRNAs dysregulated by YB1 were screened by microarray analysis in HCC cell lines.The regulation of YB1 on miR-205 and miR-200b was determined by quantitative real-time PCR,dual-luciferase reporter assay,RNA immunoprecipitation,and pull-down assay.The relationships of YB1,DGCR8,Dicer,TUT4,and TUT1 were identified by pull-down and coimmunoprecipitation experiments.The cellular co-localization of YB1,DGCR8,and Dicer were detected by immunofluorescent staining.The in vivo effect of YB1 on tumor metastasis was determined by injecting MHCC97H cells transduced with YB1 shRNA or shControl via the tail vein in nude BALB/c mice.The expression levels of epithelial tomesenchymal transition markerswere detected by immunoblotting and immunohistochemistry assays.Results:YB1 promoted HCC cell migration and tumor metastasis by regulating miR-205/200b‒ZEB1 axis partially in a Snail-independent manner.YB1 suppressedmiR-205 and miR-200b maturation by interacting with the microprocessors DGCR8 and Dicer as well as TUT4 and TUT1 via the conserved cold shock domain.Subsequently,the downregulation of miR-205 and miR-200b enhanced ZEB1 expression,thus leading to increased cell migration and invasion.Furthermore,statistical analyses on gene expression data from HCC and normal liver tissues showed that YB1 expression was positively associated with ZEB1 expression and remarkably correlated with clinical prognosis.Conclusion:This study reveals a previously undescribed mechanism by which YB1 promotes cancer progression by regulating the miR-205/200b‒ZEB1 axis in HCC cells.Furthermore,these results highlight that YB1 may play biological functions via miRNAs-mediated gene regulation,and it can serve as a potential therapeutic target in human cancers. | Xiumei Liu Di Chen Huan Chen Wen Wang Yu Liu Yawei Wang Chao Duan Zhen Ning Xin Guo Wuxiyar Otkur Jing Liu Huan Qi Xiaolong Liu Aifu Lin Tian Xia Hong-xu Liu Hai-long Piao | 2021 | Cancer Communications2021，41，7： | 1 |
| 7 | Cholesterol as a functional metabolite cooperates with metadherin in cancer cells显示文摘Protein-metabolite interactions(PMIs)play important roles in various biological processes,especially in disease progression.However,due to the complexity of living cells,it is very difficult to identify specific PMIs.Herein,we chose one oncogenic factor,metadherin(MTDH),as a bait to identify its in vivo interacting metabolites in cancer cells.Cholesterol is an important metabolite and essential structural component of cell membranes.It could also drive several diseases including cancer.Interestingly,we found that cholesterol robustly interacted with MTDH and downregulated the expression of MTDH in cancer cells.Furthermore,MTDH disturbed metabolite alterations under cholesterol treatment in MTDH transduced cancer cells.Collectively,our results uncover an undescribed PMI where MTDH,as an oncogenic factor,might positively regulate cancer progression by interacting with choleste rol.This study interprets the theoretical basis of PMI-oriented cancer progression and targeting therapies in clinic. | Wen Wang Xiaolong Liu Huan Chen Ting Ling Tian Xia Xiumei Liu Jing Liu Wuxiyar Otkur Xianzhe Shi Huan Qi Di Chen Hai-Long Piao | 2020 | Chinese Chemical Letters2020，31，7： | 0 |
| 8 | A Research on Investment Casting Technology of Ti Alloys显示文摘In this research, the materials and the compositions of the surface slurries were chosen by considering the characteristics of Ti investment casting. The effects of solid-liquid ratios on the properties of the slurry and the effects of baking temperatures on the fie-cural strength have also been investigated. Flawless shells having smooth inner surface were manufactured with proper technology. Ti and its alloys were melted and poured by water-cooled Cu crucible vacuum induction furnace. The qualities of the investment castings made accordingly were studied and analyzed. | Huiguan WAN, Xiumei QI, Jing TIAN, Yuyong CHEN, Weiqiang ZHA and Jun JIA (National Key Laboratory of Precision Hot Processing of Metals, Harbin Institute of Technology, Harbin 150001, China) | 2000 | Journal of Materials Science & Technology2000，16，1： | 0 |
| 9 | Study on the benef its of meteorological services for industries in China显示文摘It is very important to analyze and evaluate the benefi ts of meteorological services for policy decision-making and taking precautions against meteorological disasters.In this study,a model for evaluating the benef its of meteorological services for industries is constructed,with the combining method of dose-response and contingency assessment,and also absorbing other countries' experience.According to this model,and referring to the practical value of the contribution of meteorological services to typical enterprises,experts calculated the benef its of meteo-rological services for every industry.By applying this model,and taking the evaluation framework of 'to determine which industries are meteorology-sensitive' - 'to evaluate the benefi ts of meteorological services' - 'to get the total benef its of meteorological service',evaluation and analysis on the total benef its of meteorological services was done with case study.According to this study,the annual mean benef its of meteorological services are known as no less than 279.3 billion yuan(cost excluded) in present national economical environment. | Zhang Tairen Song Shanyun Tian Cuiying Zhao Rui Chai Xiumei Pan Shuangdi Li Zizhen | 2008 | Ecological Economy2008，4，4： | 0 |
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