|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Preoperative neutrophil-to-lymphocyte ratio plus platelet-to-lymphocyte ratioin predicting survival for patients with stage Ⅰ-Ⅱgastric cancer显示文摘Background:The preoperative neutrophil-to-lymphocyte ratio(NLR) and the platelet-to-lymphocyte ratio(PLR) are associated with poor prognosis of gastric cancer.We aimed to determine whether the combination of NLR and PLR(NLR-PLR) could better predict survival of patients after curative resection for stage Ⅰ-Ⅱ gastric cancer.Methods:We collected data from the medical records of patients with stage Ⅰ-Ⅱ gastric cancer undergoing curative resection between December 2000 and November 2012 at the Sun Yat-sen Cancer Center.The preoperative NLRPLR was calculated as follows:patients with both elevated NLR(≥2.1) and PLR(≥ 120) were given a score of 2,and patients with only one or neither were given a score of 1 or 0,respectively.Results:Kaplan-Meier analysis and log-rank tests revealed significant differences in overall survival(OS) among patients with NLR-PLR scores of 0,1 and 2(P < 0.001).Multivariate analysis showed that OS was independently associated with the NLR-PLR score[hazard ratio(HR) = 1.51,95%confidence interval(CI) 1.02-2.24,P = 0.039]and TNM stage(HR = 1.36,95%CI 1.01-1.83,P= 0.041).However,other systemic inflammation-based prognostic scores,including the modified Glasgow prognostic score,the prognostic nutritional index,and the combination of platelet count and NLR,were not.In TNM stage-stratified analysis,the prognostic significance of NLR-PLR was maintained in patients with stage Ⅰ(P < 0.001) and stage Ⅱ cancers(P= 0.022).In addition,the area under the receiver operating characteristic curve for the NLR-PLR score was higher than those of other systemic inflammation-based prognostic scores(P = 0.001).Conclusion:The preoperative NLR-PLR score is a useful predictor of postoperative survival in the patients with stage l-ll gastric cancer and may help identify high-risk patients for rational therapy and timely follow-up. | Xiaowei Sun Xuechao Liu Jianjun Liu Shangxiang Chen Dazhi Xu Wei Li Youqing Zhan Yuanfang Li Yingbo Chen Zhiwei Zhou | 2016 | Chinese Journal of Cancer2016，35，7： | 25 |
| 2 | Influence of plant architecture on maize physiology and yield in the Heilonggang River valley显示文摘The size and distribution of leaf area determine light interception in a crop canopy and influence overall photosynthesis and yield. Optimized plant architecture renders modern maize hybrids(Zea mays L.) more productive, owing to their tolerance of high plant densities. To determine physiological and yield response to maize plant architecture, a field experiment was conducted in 2010 and 2011. With the modern maize hybrid ZD958, three plant architectures, namely triangle, diamond and original plants, were included at two plant densities, 60,000 and 90,000 plants ha-1. Triangle and diamond plants were derived from the original plant by spraying the chemical regulator Jindele(active ingredients,ethephon, and cycocel) at different vegetative stages. To assess the effects of plant architecture, a light interception model was developed. Plant height, ear height, leaf size,and leaf orientation of the two regulated plant architectures were significantly reduced or altered compared with those of the original plants. On average across both plant densities and years, the original plants showed higher yield than the triangle and diamond plants,probably because of larger leaf area. The two-year mean grain yield of the original and diamond plants were almost the same at 90,000 plants ha-1(8714 vs. 8798 kg ha-1). The yield increase(up to 5%) of the diamonds plant at high plant densities was a result of increased kernel number per ear, which was likely a consequence of improved plant architecture in the top and middle canopy layers. The optimized light distribution within the canopy can delay leaf senescence, especially for triangle plants. The fraction of incident radiation simulated by the interception model successfully reflected plant architecture traits. Integration of canopy openness is expected to increase the simulation accuracy of the present model. Maize plant architecture with increased tolerance of high densities is probably dependent on the smaller but flatter leaves around the ear. | Shoubing Huang Yingbo Gao Yebei Li Lina Xu Hongbin Tao Pu Wang | 2017 | The Crop Journal2017，5，1： | 11 |
| 3 | A Plant Lectin Receptor-like Kinase Phosphorylates the Bacterial Effector AvrPtoB to Dampen Its Virulence in Arabidopsis显示文摘Plasma membrane-localized receptor-like kinases(RLKs)perceive conserved pathogen-associated molecular pattems(PAMPs)in plants,leading to PAMP-triggered immunity(PTI).TheArabidopsis thaliana lectin RLK LecRK-Ⅸ.2 has been shown to regulate the bacterial flagellin-derived peptide flg22-induced PTI.Here,we discover that Pseudomonas syringae effector AvrPtoB targets LecRK-Ⅸ.2 for degradation,which subsequently suppresses LecRK-Ⅸ.2-mediated PTI and disease resistance.However,LecRK-Ⅸ.2 can interact with and phosphorylate AvrPtoB at serine site 335(S335).AvrPtoB self-associates in vitro and in vivo,and the association appears to be essential for its E3 ligase activity in ubiquitinating substrate in plants.Phosphorylation of S335 disrupts the self-association and as a result,phosphomimetic AvrPtoBS335D cannot ubiquitinate LecRK-Ⅸ.2 efficiently,leading to the compromised virulence of AvrPtoB in suppressing PTI responses.fig22 enhances AvrPtoB S335 phosphorylation by inducing the expression and activating of LecRK-Ⅸ.2.Our study demonstrates that host RLKs can modify pathogen effectors to dampen their virulence and undermine their ability in suppressing PTI. | Ning Xu Xuming Luo Wei Wu Yingying Xing Yingbo Liang Yanzhi Liu Huasong Zou Hai-Lei Wei Jun Liu | 2020 | Molecular Plant2020，13，10： | 5 |
| 4 | On tame and wild bocses显示文摘We first give an alternative proof of the well-known Drozd's wild Theorem,which lowers down the dimension 43 to 20. Then we list more minimally wild bocses and discuss the possible differentials of the first arrow of a tame bocs, which is useful for reductions of bocses. | ZHANG Yingbo XU Yunge | 2005 | Science China Mathematics2005，48，4： | 3 |
| 5 | Computational and Experimental Study of Cooling Process in Coke Dry Quenching Experimental Shaft显示文摘Owing to its merits in energy savings, environmental protection and coke quality improvement, the Coke Dry Quenching (CDQ) technology is favorite in coke making industry today. In order to validate the mathematical model developed for the cooling process of real CDQ shaft, the one-seventh scale experimental setup was established. With the air as the working fluid and the coke as the packed bed, the coke and gas temperatures and the pressure drop in the cooling shaft were measured. A mathematical model based on the non-Darcian and non-thermal equilibrium model for the cooling process of the CDQ experimental shaft was presented. The computational results were compared to the experimental data. It was found that most numerical predictions were supported by the measured values. | Huafei Liu Xinxin Zhang Maolin Wu Yanhui Feng Yingbo Wang Dinan Wang Lie Xu Wenghua Zheng | 2002 | Journal of Thermal Science2002，11，2： | 2 |
| 6 | Research Progress on the Development and Application of New Natural Tobacco Humectants显示文摘The research progress on the development and application of new natural tobacco humectants was reviewed in the paper.Plants,animals and microbes contain special moisturizing substances,showing distinctive advantages and outstanding effects in respect of the tobacco moisture content maintaining and cigarette suction comfort promoting.The development necessity,major types,functional mechanism and influence on cigarette quality of new natural tobacco humectants development were compared and elaborated.Additionally,the prospect of new natural tobacco humectants development and application was forecasted. | Xiaojing MA Xinge LIU Zhiqiang XU Yingbo XU Huai WANG Risheng YAO | 2016 | Agricultural Science & Technology2016，17，5： | 2 |
| 7 | Pyrolysis behavior of pectin under the conditions that simulate cigarette smoking显示文摘 | Shun Zhou Yingbo Xu Chenghui Wang Zhenfeng Tian | 2011 | Journal of Analytical and Applied Pyrolysis2011，，1： | 1 |
| 8 | A chromosome-scale genome assembly of Dasypyrum villosum provides insights into its application as a broad-spectrum disease resistance resource for wheat improvement显示文摘Dasypyrum villosum is one of the most valuable gene resources in wheat improvement,especially for disease resistance.The mining of favorable genes from D.villosum is frustrated by the lack of a whole genome sequence.In this study,we generated a doubled-haploid line,91C43^(DH),using microspore culture and obtained a 4.05-GB high-quality,chromosome-scale genome assembly for D.villosum.The assembly contains39727 high-confidence genes,and 85.31% of the sequences are repetitive.Two reciprocal translocation events were detected,and 7VS-4VL is a unique translocation in D.villosum.The prolamin seed storage protein-coding genes were found to be duplicated;in particular,the genes encoding low-molecular-weight glutenin at the Glu-V3 locus were significantly expanded.RNA sequencing(RNA-seq)analysis indicated that,after Blumeria graminearum f.sp tritici(Bgt)inoculation,there were more upregulated genes involved in the pattern-triggered immunity and effector-triggered immunity defense pathways in D.villosum than in Triticum urartu.MNase hypersensitive sequencing(MH-seq)identified two Bgt-inducible MH sites(MHSs),one in the promoter and one in the 3'terminal region of the powdery mildew resistance(Pm)gene NLR1-V.Each site had two subpeaks and they were termed MHS1(MHS1.1/1.2)and MHS2(MHS2.1/2.2).Bgt-inducible MHS2.2 was uniquely present in D.villosum,and MHS1.1 was more inducible in D.villosum than in wheat,suggesting that MHSs may be critical for regulation of NLR1-V expression and plant defense.In summary,this study provides a valuable genome resource for functional genomics studies and wheat-D.villosum introgression breeding.The identified regulatory mechanisms may also be exploited to develop new strategies for enhancing Pm resistance by optimizing gene expression in wheat. | Xu Zhang Haiyan Wang Haojie Sun Yingbo Li Yilong Feng Chengzhi Jiao Mengli Li Xinying Song Tong Wang Zongkuan Wang Chunxia Yuan Li Sun Ruju Lu Wenli Zhang Jin Xiao Xiue Wang | 2023 | Molecular Plant2023，16，2： | 1 |
| 9 | Optimaldesign of spatial source-and-relay matrices for a non-regenerative two-way mimo relay system显示文摘 | XU Shengyang HUA Yingbo | 2011 | IEEE Transactions on Wireless Communications2011，10，5： | 1 |
| 10 | Thermal degradation and combustion behavior of reconstituted tobacco sheet treated with ammonium polyphosphate显示文摘 | ZHOU Shun NING Min XU Yingbo | 2013 | Journal of Analytical and Applied Pyrolysis2013，100，： | 1 |
| 11 | Indecomposability and the number of links显示文摘 | Yunge Xu Yingbo Zhang | 2001 | Science in China Series A: Mathematics2001，，12： | 1 |
| 12 | On tame and wild bocses显示文摘 | Yingbo Zhang Yunge Xu | 2005 | Science in China Series A: Mathematics2005，，4： | 1 |
| 13 | Indecomposability and the number of links显示文摘 | Yunge Xu Yingbo Zhang | 2001 | Science in China Series A: Mathematics2001，，12： | 1 |
| 14 | Effect of urea phosphate on thermal decomposition of reconstituted tobacco and CO evolution显示文摘 | Ge shaolin Xu Yingbo Tian Zhengfeng | 2013 | Journal of Analvtical and Applied Pyrolysis2013，99，： | 1 |
| 15 | The pyrolysis of cigarette paper under the conditions that simulate cigarette smouldering and puffing显示文摘 | Zhou Shun Wang Chenghui Xu Yingbo | 2011 | J Therm Anal Calorim2011，104，3： | 1 |
| 16 | Bioleaching of different copper sulfides by Acidithiobacillus ferrooxidans and its adsorption on minerals显示文摘 | DONG Yingbo LIN Hai XU Xiaofang | 2013 | Hydrometallurgy2013，140，： | 1 |
| 17 | Comparative study on the bioleaching, biosorption and passivation of copper sulfide minerals显示文摘 | DONG Yingbo LIN Hai XU Xiaofang | 2013 | International Biodeterioration & Biodegradation2013，，： | 1 |
| 18 | Comparative study on the bioleaching, biosorption and passivation of copper sulfide minerals显示文摘 | Yingbo Dong Hai Lin Xiaofang Xu Yue Zhang Yuejiao Gao Shanshan Zhou | 2013 | International Biodeterioration & Biodegradation2013，，： | 1 |
| 19 | Effects of quartz addition on chalcopyrite bioleaching in shaking flasks显示文摘 | Yingbo B. Dong Hai Lin Shanshan Zhou Xiaofang Xu Yue Zhang | 2013 | Minerals Engineering2013，，： | 1 |
| 20 | Effect of urea phosphate on thermal decomposition of reconstituted tobacco and CO evolution显示文摘 | IGe Shaolin Xu Yingbo | 2015 | Journal of Analytical and Applied Pyrolysis2015，99，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员