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| 1 | Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth显示文摘 | Yuan Yin Xing Cai Xi Chen Hongwei Liang Yujing Zhang Jing Li Zuoyun Wang Xiulan Chen Wen Zhang Seiji Yokoyama Cheng Wang Liang Li Limin Li Dongxia Hou Lei Dong Tao Xu Takachika Hiroi Fuquan Yang Hongbin Ji Junfeng Zhang Ke Zen Chen-Yu Zhang | 2014 | Cell Research2014，24，10： | 33 |
| 2 | Influence of plant architecture on maize physiology and yield in the Heilonggang River valley显示文摘The size and distribution of leaf area determine light interception in a crop canopy and influence overall photosynthesis and yield. Optimized plant architecture renders modern maize hybrids(Zea mays L.) more productive, owing to their tolerance of high plant densities. To determine physiological and yield response to maize plant architecture, a field experiment was conducted in 2010 and 2011. With the modern maize hybrid ZD958, three plant architectures, namely triangle, diamond and original plants, were included at two plant densities, 60,000 and 90,000 plants ha-1. Triangle and diamond plants were derived from the original plant by spraying the chemical regulator Jindele(active ingredients,ethephon, and cycocel) at different vegetative stages. To assess the effects of plant architecture, a light interception model was developed. Plant height, ear height, leaf size,and leaf orientation of the two regulated plant architectures were significantly reduced or altered compared with those of the original plants. On average across both plant densities and years, the original plants showed higher yield than the triangle and diamond plants,probably because of larger leaf area. The two-year mean grain yield of the original and diamond plants were almost the same at 90,000 plants ha-1(8714 vs. 8798 kg ha-1). The yield increase(up to 5%) of the diamonds plant at high plant densities was a result of increased kernel number per ear, which was likely a consequence of improved plant architecture in the top and middle canopy layers. The optimized light distribution within the canopy can delay leaf senescence, especially for triangle plants. The fraction of incident radiation simulated by the interception model successfully reflected plant architecture traits. Integration of canopy openness is expected to increase the simulation accuracy of the present model. Maize plant architecture with increased tolerance of high densities is probably dependent on the smaller but flatter leaves around the ear. | Shoubing Huang Yingbo Gao Yebei Li Lina Xu Hongbin Tao Pu Wang | 2017 | The Crop Journal2017，5，1： | 11 |
| 3 | Engineering an enthesis-like graft for rotator cuff repair:An approach to fabricate highly biomimetic scaffold capable of zone-specifically releasing stem cell differentiation inducers显示文摘Rotator cuff(RC)attaches to humerus across a triphasic yet continuous tissue zones(bone-fibrocartilage-tendon),termed“enthesis”.Regrettably,rapid and functional enthesis regeneration is challenging after RC tear.The existing grafts bioengineered for RC repair are insufficient,as they were engineered by a scaffold that did not mimic normal enthesis in morphology,composition,and tensile property,meanwhile cannot simultaneously stimulate the formation of bone-fibrocartilage-tendon tissues.Herein,an optimized decellularization approach based on a vacuum aspiration device(VAD)was developed to fabricate a book-shaped decellularized enthesis matrix(O-BDEM).Then,three recombinant growth factors(CBP-GFs)capable of binding collagen were synthesized by fusing a collagen-binding peptide(CBP)into the N-terminal of BMP-2,TGF-β3,or GDF-7,and zone-specifically tethered to the collagen of O-BDEM to fabricate a novel scaffold(CBP-GFs/O-BDEM)satisfying the above-mentioned requirements.After ensuring the low immunogenicity of CBP-GFs/O-BDEM by a novel single-cell mass cytometry in a mouse model,we interleaved urine-derived stem cell-sheets into this CBP-GFs/O-BDEM to bioengineer an enthesis-like graft.Its high-performance on regenerating enthesis was determined in a canine model.These findings indicate this CBP-GFs/O-BDEM may be an excellent scaffold for constructing enthesis-like graft to patch large/massive RC tears,and provide breakthroughs in fabricating graded interfacial tissue. | Can Chen Qiang Shi Muzhi Li Yang Chen Tao Zhang Yan Xu Yunjie Liao Shulin Ding Zhanwen Wang Xing Li Chunfeng Zhao Lunquan Sun Jianzhong Hu Hongbin Lu | 2022 | Bioactive Materials2022，7，10： | 4 |
| 4 | Roles of insulin-like growth factor Ⅱ in regulating female reproductive physiology显示文摘The number of growth factors involved in female fertility has been extensively studied, but reluctance to add essential growth factors in culture media has limited progress in optimizing embryonic growth and implantation outcomes, a situation that has ultimately led to reduced pregnancy outcomes. Insulin-like growth factor Ⅱ(IGF-Ⅱ) is the most intricately regulated of all known reproduction-related growth factors characterized to date, and is perhaps the predominant growth factor in human ovarian follicles. This review aims to concisely summarize what is known about the role of IGF-Ⅱ in follicular development, oocyte maturation, embryonic development, implantation success, placentation, fetal growth, and in reducing placental cell apoptosis, as well as present strategies that use growth factors in culture systems to improve the developmental potential of oocytes and embryos in different species. Synthesizing the present knowledge about the physiological roles of IGF-Ⅱ in follicular development, oocyte maturation, and early embryonic development should, on the one hand, deepen our overall understanding of the potential beneficial effects of growth factors in female reproduction and on the other hand support development(optimization) of improved outcomes for assisted reproductive technologies. | Tahir Muhammad Mengjing Li Jianfeng Wang Tao Huang Shigang Zhao Han Zhao Hongbin Liu Zi-Jiang Chen | 2020 | Science China(Life Sciences)2020，63，6： | 4 |
| 5 | Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer’s disease mouse model显示文摘Photobiomodulation,by utilizing low-power light in the visible and near-infrared spectra to trigger biological responses in cells and tissues,has been considered as a possible therapeutic strategy for Alzheimer’s disease(AD),while its specific mechanisms have remained elusive.Here,we demonstrate that cognitive and memory impairment in an AD mouse model can be ameliorated by 1070-nm light via reducing cerebralβ-amyloid(Aβ)burden,the hallmark of AD.The glial cells,including microglia and astrocytes,play important roles in Aβclearance.Our results show that 1070-nm light pulsed at 10 Hz triggers microglia rather than astrocyte responses in AD mice.The 1070-nm lightinduced microglia responses with alteration in morphology and increased colocalization with Aβare sufficient to reduce Aβload in AD mice.Moreover,1070-nm light pulsed at 10 Hz can reduce perivascular microglia and promote angiogenesis to further enhance Aβclearance.Our study confirms the important roles of microglia and cerebral vessels in the use of 1070-nm light for the treatment of AD mice and provides a framework for developing a novel therapeutic approach for AD. | Lechan Tao Qi Liu Fuli Zhang Yuting Fu Xi Zhu Xiaofu Weng Hongbin Han Yong Huang Yuanzhen Suo Liang Chen Xiaoling Gao Xunbin Wei | 2021 | Light(Science & Applications)2021，10，10： | 4 |
| 6 | Electron-withdrawing functional ligand promotes CO2 reduction catalysis in single atom catalyst显示文摘Electrochemical carbon dioxide reduction reaction (CO2RR) powered by renewable electricity offers an attractive approach to reduce carbon emission and at the same time produce valuable chemicals/fuels.To design efficient CO2 reduction electrocatalyst,it is important to understand the structure-activity relationship.Herein,we design a series of single Co atoms electrocatalysts with well-defined active sites electronic structures,which exhibit outstanding CO2RR activity with controllable selectivity to CO.Experimental and density functional theory (DFT) calculation studies show that introducing nitro (amino) ligand next to single Co atom catalytic center with electron-withdrawing (electron-donating) capability favors (hinders) CO2 reduction catalysis.This work provides an in-depth understanding of how functional ligand affects the splitting of transition metal 3d electron orbital,thereby changing the electron transfer from transition metal active site to CO2,which is closely related to the Gibbs free energy of the rate-determining step (CO2+e^-+*→*CO2^-). | Xinyi Ren Song Liu Huicong Li Jie Ding Linghui Liu Zhichong Kuang Ling Li Hongbin Yang Fuquan Bai Yanqiang Huang Tao Zhang Bin Liu | 2020 | Science China Chemistry2020，63，12： | 3 |
| 7 | Rational design of carbon-based metal-free catalysts for electrochemical carbon dioxide reduction: A review显示文摘Electrochemical CO2 reduction to chemicals or fuels presents one of the most promising strategies for managing the global carbon balance, which yet poses a significant challenge due to lack of efficient and durable electrocatalyst as well as the understanding of the CO2 reduction reaction(CO2RR) mechanism.Benefiting from the large surface area, high electrical conductivity, and tunable structure, carbon-based metal-free materials(CMs) have been extensively studied as cost-effective electrocatalysts for CO2RR.The development of CMs with low cost, high activity and durability for CO2RR has been considered as one of the most active and competitive directions in electrochemistry and material science.In this review article,some up-to-date strategies in improving the CO2RR performance on CMs are summarized.Specifically, the approaches to optimize the adsorption of CO2RR intermediates, such as tuning the physical and electronic structure are introduced, which can enhance the electrocatalytic activity of CMs effectively.Finally, some design strategies are proposed to prepare CMs with high activity and selectivity for CO2RR. | Song Liu Hongbin Yang Xiong Su Jie Ding Qing Mao Yanqiang Huang Tao Zhang Bin Liu | 2019 | Journal of Energy Chemistry2019，28，9： | 3 |
| 8 | Nitrogen removal from summer to winter in a field pilot-scale multistage constructed wetland-pond system显示文摘A pilot-scale multistage constructed wetland-pond(MCWP)system with a'pre-ecological oxidation pond,two-stage horizontal subsurface flow constructed wetland(HSCW)and surface flow constructed wetland(SFCW)as the core and postsubmerged plant pond'as the process was used to treat actual polluted river water in the field,and the variation in nitrogen removal from summer to winter was investigated.The results showed that the average total nitrogen(TN)removal efficiency in the MCWP was approximately 40.74%.The significant positive correlation between the daily highest temperature and the TN removal efficiency of the whole system was fitted with a nonlinear curve(R^(2)=0.7192).The TN removal load rate in the HSCWs was 2.7–3.7 times that in the SFCW.The SFCW,which had high-density plants(35 plants/m^(2)),increased the proportion of nitrogen removed by plant harvesting and microbial function.The TN transformed by Iris pseudacorus L.accounted for 54.53%in the SFCW.Furthermore,bacteria completed the nitrogen cycle in the SFCW through a variety of nitrogen removal pathways.This research not only investigated the TN removal performance in an MCWP system but also made it possible to predict the TN removal efficiency according to the daily highest temperature from summer to winter in the field. | Tao Wang Liping Xiao Hongbin Lu Shaoyong Lu Jiaxin Li Xiaochun Guo Xiaoliang Zhao | 2022 | Journal of Environmental Sciences2022，34，1： | 2 |
| 9 | Current State and Development of Quaternary Ammonium Compounds Disinfectants in China显示文摘Quaternary ammonium compound are a class of broad-spectrum,high-efficiency and low-toxicity bactericide,which are widely used in daily life and industrial sterilization.Herein,the current state of domestic quaternary ammonium disinfectant products was summarized,as well as those new products developed and studied,and the development trend was also predicted. | Jiang Yajie Ju Hongbin Wang Yakui Geng Tao Li Yunling | 2020 | China Detergent & Cosmetics2020，5，2： | 2 |
| 10 | Transition to a two-level linear state estimator-Part I: architecture显示文摘 | Tao Yang Hongbin Sun Bose A | 2011 | IEEE Transactions on Power Systems2011，26，1： | 1 |
| 11 | Transition to a two-level linear state estimator-Part II: algorithm显示文摘 | Yang Tao Sun Hongbin Bose A | 2011 | IEEE Transactions on Power Systems2011，26，1： | 1 |
| 12 | Cloning and characterization of human Golgi phosphoprotein 2 gene ( GOLPH2 / GP73 / GOLM1 ) promoter显示文摘 | Yu Gong Qi Long Hongbin Xie Tianyu Zhang Tao Peng | 2012 | Biochemical and Biophysical Research Communications2012，，4： | 1 |
| 13 | Transition to a two-level linear state estimator-Part I:Architecture显示文摘 | Tao Yang Hongbin Sun Bose A | 2011 | IEEE Trans on Power Systems2011，26，1： | 1 |
| 14 | Clinical outcomes of remnant preserving augmentation in anterior cruciate ligament reconstruction: a systematic review显示文摘 | Jianzhong Hu Jin Qu Daqi Xu Tao Zhang Jingyong Zhou Hongbin Lu | 2014 | Knee Surgery, Sports Traumatology, Arthroscopy2014，，9： | 1 |
| 15 | VUV-UV excited luminescent properties of calcium borophosphate doped with rare earth ions显示文摘 | LIANG Hongbin ZENG Qinghua TAO Ye | 2003 | Materials Science and Engineering2003，98，： | 1 |
| 16 | Synthetic vitamin K analogs inhibit inflammation by targeting the NLRP3 inflammasome显示文摘Vitamin K refers to a group of structurally similar vitamins that are essential for proper blood coagulation,as well as bone and cardiovascular health.Previous studies have indicated that vitamin K may also have anti-inflammatory properties,although the underlying mechanisms of its anti-inflammatory effects remain unclear.The NLRP3 inflammasome is a multiprotein complex,and its activation leads to IL-1βand IL-18 secretion and contributes to the pathogenesis of various human inflammatory diseases.Here,we show that synthetic vitamins K3 and K4 are selective,potent inhibitors of the NLRP3 inflammasome and specifically block the interaction between NLRP3 and ASC,thereby inhibiting NLRP3 inflammasome assembly.Moreover,we show that treatment with vitamin K3 or K4 attenuates the severity of inflammation in a mouse model of peritonitis.Our results demonstrate that vitamins K3 and K4 exert their anti-inflammatory effects by inhibiting NLRP3 inflammasome activation and indicate that vitamin K supplementation may be a treatment option for NLRP3-associated inflammatory diseases. | Xicui Zheng Yingting Hou Hongbin He Yun Chen Rongbin Zhou Xiaqiong Wang Tao Gong Wei Jiang | 2021 | Cellular & Molecular Immunology2021，18，10： | 1 |
| 17 | A multi-location joint field observation of the stratosphere and troposphere over the Tibetan Plateau显示文摘The unique geographical location and high altitude of the Tibetan Plateau can greatly influence regional weather and climate.In particular, the Asian summer monsoon(ASM) anticyclone circulation system over the Tibetan Plateau is recognized to be a significant transport pathway for water vapor and pollutants to enter the stratosphere. To improve understanding of these physical processes, a multi-location joint atmospheric experiment was performed over the Tibetan Plateau from late July to August in 2018, funded by the fiveyear(2018–2022) STEAM(stratosphere and troposphere exchange experiment during ASM) project, during which multiple platforms/instruments—including long-duration stratospheric balloons, dropsondes, unmanned aerial vehicles, special sounding systems, and ground-based and satellite-borne instruments—will be deployed. These complementary methods of data acquisition are expected to provide comprehensive atmospheric parameters(aerosol, ozone, water vapor, CO_2, CH_4, CO, temperature, pressure,turbulence, radiation, lightning and wind); the richness of this approach is expected to advance our comprehension of key mechanisms associated with thermal, dynamical, radiative, and chemical transports over the Tibetan Plateau during ASM activity. | JinQiang Zhang Yi Liu HongBin Chen ZhaoNan Cai ZhiXuan Bai LingKun Ran Tao Luo Jing Yang YiNan Wang YueJian Xuan YinBo Huang XiaoQing Wu JianChun Bian DaRen Lu | 2019 | Earth and Planetary Physics2019，3，2： | 1 |
| 18 | VUV- UV photoluminescence spectra of strontium orthophosphate doped with rare earth ions 显示文摘 | Hongbin Liang Ye Tao Qiang Su | 2002 | J Solid State Chem2002，167，： | 1 |
| 19 | Transition to a two-level linear state estimator:PartⅠarchitecture显示文摘 | YANG Tao SUN Hongbin BOSE A | 2011 | IEEE Trans on Power Systems2011，26，1： | 1 |
| 20 | Transition to a two-level linear state estimator:PartⅡalgorithm显示文摘 | YANG Tao SUN Hongbin BOSE A | 2011 | IEEE Trans on Power Systems2011，26，1： | 1 |
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