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| 1 | Inulin Can Alleviate Metabolism Disorders in ob/ob Mice by Partially Restoring Leptinrelated Pathways Mediated by Gut Microbiota显示文摘Inulin has been used as a prebiotic to alleviate glucose and lipid metabolism disorders in mice and humans by modulating the gut microbiota. However, the mechanism underlying the alleviation of metabolic disorders by inulin through interactions between the gut microbiota and host cells is unclear. We use ob/ob mice as a model to study the effect of inulin on the cecal microbiota by16 S rRNA gene amplicon sequencing and its interaction with host cells by transcriptomics. The inulin-supplemented diet improved glucose and lipid metabolism disorder parameters in ob/ob mice,alleviating fat accumulation and glucose intolerance. The a diversity of gut microbial community of ob/ob mice was reduced after inulin treatment, while the b diversity tended to return to the level of wild type mice. Interestingly, Prevotellaceae UCG 001(family Prevotellaceae) was obviously enriched after inulin treatment. A comparative analysis of the gene expression profile showed that the cecal transcriptome was changed in leptin gene deficiency mice, whereas the inulin-supplemented diet partially reversed the changes in leptin gene-related signaling pathways, especially AMPK signaling pathway, where the levels of gene expression became comparable to those in wild type mice.Further analysis indicated that Prevotellaceae UCG 001 was positively correlated with the AMPK signaling pathway, which was negatively correlated with markers of glycolipid metabolism disorders. Our results suggest that the inulin-supplemented diet alleviates glucose and lipid metabolism disorders by partially restoring leptin related pathways mediated by gut microbiota. | Xiaofeng Song Liang Zhong Na Lyu Fei Liu Boxing Li Yanan Hao Yong Xue Jing Li Yuqing Feng Yue Ma Yongfei Hu Baoli Zhu | 2019 | Genomics, Proteomics & Bioinformatics2019，17，1： | 12 |
| 2 | The Distribution and Concentration Monitoring of Benzene Industries—Six PLADs,China,2020显示文摘Summary What is already known about this topic?Benzene is classified as a Class I human carcinogen by the International Agency for Research on Cancer.Long-term exposure to benzene increases the risk of chronic benzene poisoning and leukemia.However,benzene is still widely used in the manufacturing industry.What is added by this report? | Xue Wang Jin Zhou Lei Han Xiurong Cheng Hua Shao Qiang Jia Peiyu Xu Jing Liu Jie Ren Jin Li Fei Li Baoli Zhu Meibian Zhang Caihong Xing | 2021 | China CDC weekly2021，3，43： | 4 |
| 3 | Characterization of human αβTCR repertoire and discovery of D-D fusion in TCRβ chains显示文摘 | Peipei Liu Di Liu Xi Yang Jing Gaoai Ma3, Fangqing Zhaos, Xuyu Zhou~'2~, George F. Gao1'2'4'5~, Baoli Zhu~'2~ Yan Chen Xue Xiao Fei Liu Jing Zou Jun Wu Juncai Ma Fangqing Zhao Xuyu Zhou George F. Gao Baoli Zhu | 2014 | Protein & Cell2014，5，8： | 1 |
| 4 | Leech sargentgloryvine stem decoction treatment, 116 cases of ovarian cyst 显示文摘 | Yang xiu-juan Xue Baoli Sun haiying | 2006 | Chinese folk thera- py2006，，2： | 1 |
| 5 | Size engineering of 2D MOF nanosheets for enhanced photodynamic antimicrobial therapy显示文摘Although porphyrin-based metal-organic frameworks(MOFs)have been widely explored as photosensitizers for photodynamic therapy,how the size will affect the light-induced catalytic activity for generation of reactive oxygen species(ROS)still remain unclear.Herein,we first report the size-controlled synthesis of two-dimensional(2D)porphyrin-based PCN-134 MOF nanosheets by a two-step solvothermal method to explore the size effect on its PDT performance,thus yielding enhanced photodynamic antimicrobial therapy.By simply controlling the reaction temperature in the synthesis process,the bulk PCN-134 crystal,large PCN-134(L-PCN-134)nanosheets with a lateral size of 2–3μm and thickness of 33.2–37.5 nm and small PCN-134 nanosheets(S-PCN-134)with a lateral size of 160–180 nm and thickness of 9.1–9.7 nm were successfully prepared.Interestingly,the S-PCN-134 nanosheets exhibit much higher photodynamic activity for ROS generation than that of the bulk 3D PCN-134 crystal and L-PCN-134 nanosheets under a660 nm laser irradiation,suggesting that the photodynamic activity of PCN-134 MOF increases when the size reduces.Therefore,the S-PCN-134 nanosheets show much enhanced performance when used as a photosensitizer for photodynamic antimicrobial activity and wound healing. | Baoli Xue Xiwen Geng Haohao Cui Huiying Chen Zhikang Wu Hong Chen Hai Li Zhan Zhou Meiting Zhao Chaoliang Tan Jingguo Li | 2023 | Chinese Chemical Letters2023，34，9： | 0 |
| 6 | Industry Distribution Characteristics of Benzene-Induced Leukemia—7 PLADs,China,2005–2019显示文摘Summary What is already known about this topic?In the 1980s.benzene-induced leukemia(BIL)mainly occurred in shoemaking and painting industries.Now the industry distribution of benzene-induced leukemia may have changed over time.What is added by this report?BlL cases mainly occurred in the manufacturing industry from 2005-2019,especially in private enterprises and small/medium-sized enterprises.The industry with the largest number of new cases of BIL was the general and special equipment manufacturing.The number of leukemia cases in emerging industries such as computer/electronic product manufacturing was found to be increasing.What are the implications for public health practice?Strengthening supervision and regulation of manufacturing,especially of small/medium-sized enterprises and emerging manufacturing industry,may be effective in reducing BIL. | Jinzhe Li Yuan Zhao Xiurong Cheng Lei Han Xue Wang Qiang Jia Shang Gao Peiyu Xu Zihuan Wang Jin Li Xinglin Fang Jiabin Chen Baoli Zhu Meibian Zhang Caihong Xing | 2022 | China CDC weekly2022，4，17： | 0 |
| 7 | Observations of the solar corona during the total solar eclipse on 21 August 2017显示文摘The Sun’s tenuous outer atmosphere,the corona,emits only about one-millionth as much light as the solar surface.In ancient times the corona was observed by human beings only during total solar eclipses,when the strong emission of visible light from the photosphere was completely blocked by the Moon.In 1931, | Hui Tian ZhongQuan Qu YaJie Chen LinHua Deng ZhengHua Huang Hao Li Yue Zhong Yu Liang JingWen Zhang YiGong Zhang BaoLi Lun XiangMing Cheng XiaoLi Yan ZhiKe Xue YuXin Xin ZhiMing Song YingJie Zhu Tanmoy Samanta | 2017 | Earth and Planetary Physics2017，1，1： | 0 |
| 8 | Industry Distribution Characteristics of Benzene-ExposedWorkers with Cytopenia - Four Provinces, China, 2020显示文摘What is already known about this topic?Benzene is harmful to the hematopoietic system and can cause leukemia.However,benzene is still being used in various industries including furniture,rubber,plastic products,and metal product manufacturing.What is added by this report?The white blood cell count of workers in general equipment,special equipment,chemical raw materials,and chemical products manufacturing decreased significantly.The enterprises in which benzene concentration exceeded the occupational exposure limit were small enterprises and private enterprises.What are the implications for public health practice?Regular health examinations are necessary for benzeneexposed workers.In addition,the monitoring of benzene concentration in small enterprises and private enterprises should be strengthened. | Dongning Hua Xue Wang Lei Han Jin Zhou Xiurong Cheng Boshen Wang Juan Zhang Jinzhe Li Peiyu Xu Shang Gao Lifang Zhou Fei Li Xinglin Fang Jin Li Zihuan Wang Jing Liu Jie Ren Baoli Zhu Meibian Zhang Caihong Xing | 2022 | China CDC weekly2022，4，51： | 0 |
| 9 | Structure-activity relationship of defective electrocatalysts for nitrogen fixation显示文摘Ammonia(NH_(3)), as an important chemical substance and clean energy carrier, plays an indispensable role in industrial and agricultural production. The electrocatalytic synthesis of NH+3 under mild conditions has attracted worldwide attention in the energy field due to its environmental friendliness and cost efficiency,but unsatisfactory NH_(3) yields and Faradaic efficiencies are restricting its development. The introduction of defect has been demonstrated as a feasible way to overcome the disadvantages of electrochemistry, as it can regulate the electronic structure and modulate coordination environment of electrocatalysts, which further create active sites and enhance nitrogen adsorption. In this regard, it is necessary to understand the effects of various types of defects on electrocatalysts based on the latest progress in the defect engineering for nitrogen reduction reaction(NRR). In this review, the concept, classifications, and characterization of defects as well as the approaches to create them in electrocatalysts are firstly discussed.Then, certain types of defects(vacancy, dopant, amorphism, edge/corner, and porousness) affecting the performances of various electrocatalysts are further described. Finally, the summary and challenges of electrocatalytic ammonia synthesis are proposed to design advanced electrocatalysts with high efficiency. | Yusheng Wang Nan Yang Xue Xin Yingjie Yu Yuao Wei Baoli Zha Wenjing Liu | 2023 | Chinese Chemical Letters2023，34，7： | 0 |
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