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| 1 | Nab-paclitaxel(abraxane)-based chemotherapy to treat elderly patients with advanced non-small-cell lung cancer:a single center,randomized and open-label clinical trial显示文摘Background:The purpose of this study is to evaluate the clinical efficacy and safety of abraxane-based chemotherapy with/without nedaplatin in elderly patients with non-small-cell lung cancer(NSCLC).Materials and methods:From October 2009 to January 2013,48 elderly patients(>65 years) with NSCLC were investigated in this clinical trial.The patients were randomized and equally allocated into arms A and AP:(A) abraxane(130 mg/m^2,days 1,8);(B) abraxane + nedaplatin(20 mg/m^2 days 1-3,q3w).The parameters of objective response rate(ORR),disease control rate(DCR),progression-free survival(PFS),overall survival(OS) and side effects were evaluated between two arms.Results:Over 80%of the patients completed four cycles of chemotherapy.The total ORR was 21.3%,DCR was 55.3%,PFS 4.5 months and OS 12.6 months.No significant difference was found between arms A and AP in terms of ORR(16.7%vs.26.1%,P=0.665) or DCR(55.3%vs.56.5%,P=0.871).The median PFS in arm A was 3.3 months[25-75%confidence interval(CI):3.1-7.2]and 5.5 months(25-75%CI:3.2-7.0) in arm AP with no statistical significance(P=0.640).The median OS in arm A was 12.6 months(25-75%CI:5.7-26.2) and 15.1 months(25-75%CI:6.4-35.3) in arm AP with no statistical significance(P=0.770).The side effects were mainly grade 1-2.The incidence of grade 3-4 toxicities was 29.1%in arm A and 62.5%in arm AP with a statistical significance(P=0.020).Conclusions:Compared with combined therapy,abraxane alone chemotherapy was beneficial for elderly NSCLC patients with better tolerability and less adverse events,whereas did not significantly differ in terms of ORR,DCR,PFS or OS. | Hanrui Chen Xuewu Huang Shutang Wang Xinting Zheng Jietao Lin Peng Li Lizhu Lin | 2015 | Chinese Journal of Cancer Research2015，27，2： | 12 |
| 2 | Autonomous navigation method and technology implementation of high-precision solar spectral velocity measurement显示文摘The velocity information of spacecraft can be directly obtained by the autonomous navigation method based on astronomical spectral velocity measurement. It provides complete direct velocity measurement information for the traditional navigation methods represented by astronomical angle measurement and astronomical ranging, which is of great significance for spacecraft high precision autonomous navigation. This paper comprehensively introduces the principle and navigation method of astronomical spectral velocity measurement, as well as the technical realization of the solar atomic frequency discriminator for autonomous navigation(SAFDAN) based on atomic frequency discrimination velocity measurement. The new SAFDAN is the first instrument to measure the Doppler velocity of spacecraft relative to the Sun. Carried by the CHASE mission, the in-orbit experiment of the SAFDAN is realized, and the in-orbit velocity measurement accuracy reaches 1.93 m/s, which effectively verifies the feasibility of the astronomical spectral velocity measurement method and technology. | Wei Zhang Yong Yang Wei You JinZhou Zheng Hui Ye KaiJun Ji Xiao Chen Xin Lin QingLong Huang XueWu Cheng Wei Zhang FaQuan Li | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 3 |
| 3 | Vapor film collapse triggered by external pressure pulse and the fragmentation of melt droplet in FCIs显示文摘The fragmentation process of high-temperature molten drop is a key factor to determine the ratio heat transferred to power in FCIs,which estimates the possible damage degree during the hypothetical severe accident in the nuclear reactors. In this paper,the fragmentation process of melt droplet in FCIs is investigated by theoretic analysis. The fragmentation mechanism is studied when an external pressure pulse applied to a melt droplet,which is surrounded by vapor film. The vapor film collapse which induces fragmentation of melt droplet is analyzed and modeled. And then the generated pressure is calculated. The vapor film collapse model is introduced to fragmentation correlation,and the predicted fragment size is calculated and compared with experimental data. The result shows that the developed model can predict the diameter of fragments and can be used to calculate the fragmentation process appreciatively. | LIN Qian TONG Lili CAO Xuewu KRIVENTSEV Vladimir | 2008 | Nuclear Science and Techniques2008，19，4： | 2 |
| 4 | Joint observation results of Na layer and ionosphere in Wuhan during the Total Solar Eclipse显示文摘During the total solar eclipse on July 22, 2009 in Wuhan, the joint observation test of Na layer and ionosphere was conducted by using the daytime observation atmospheric lidar and the GPS ionosphere detector. The results show that the full width at half maximum(FWHM) of Na layer density slightly narrowed during the total solar eclipse and broadened after the eclipse, while the height of Na peak slightly decreased in the eclipse and increased after the eclipse. These implying that Na layer changes reflect the rapid process of sunrise and sunset. The ionosphere total electron content(TEC) and the sky background light noise also presented an obvious fluctuation characteristic with the changes of solar irradiation during the process of total solar eclipse. The difference lies in that the changes of FWHM of Na layer atoms are much slower than that of ionosphere, the reason for this might be that the Na layer, after being disturbed by the total solar eclipse, will generate a series of complicated photochemical reactions and momentum transport processes, and then recombine the Na atoms. The Na atoms to be detected by the lidar need a lag process, which rightly conforms to the theoretical simulated results. | CHENG XueWu YANG Yong WANG ZeLong LI FaQuan YANG GuoTao ZHAO ZhengYu GONG Wei WANG JiHong HU Xiong LIN Xin WU XiaoCheng SONG ShaLei GONG ShunSheng | 2016 | Science China Earth Sciences2016，59，2： | 1 |
| 5 | Ferroelectric Potassium Lithium Niobate Crystals Grown by the Vertical Bridgman Method显示文摘 | Xu Jiayue Fan Shiji Lin Yafang Xu Xuewu | 2001 | Materials Science & Engineering B2001，85，： | 1 |
| 6 | Activity-trip chaining behavior of urban low-income populations in Nanjing, China: A structural equations analysis显示文摘 | Zhaoming Chu Hui Chen Lin Cheng Xuewu Chen Senlai Zhu | 2014 | Discrete Dynamics in Nature and Society2014，，： | 1 |
| 7 | Moving cancer diagnostics from bench to bedside显示文摘 | Xuewu Zhang Lin Li Dong Wei Yeeleng Yap Feng Chen | 2007 | Trends in Biotechnology2007，，4： | 1 |
| 8 | Simple and Efficient Cultivation Technology for the Peanut under the Standardization Mode of Single-seed Sowing显示文摘Single-seed sowing is a new,simple and efficient cultivation mode for peanut that realized from cultivation of healthy individual and construction of high-yielding population. The cultivation mode has the obvious advantages in uniform seedling,strong sprouting,seed saving and cost saving,thus it is considered as one of the effective ways for high-yield and high-efficient peanut cultivation in China in the future.Through integrating with other high-efficiency and simple cultivation measures,the single-seed sowing technology system has made conforming to China's national standardization cultivations of peanut and the technology was already applied in the main producing areas of peanut and gained the significant efficiency and abroad application prospects. Based on many years of researches in single-seed sowing technology,high-efficiency fertilization and scientific chemical control in the research team,by combining with the latest research results in plant protection and machinery,this paper described the key points and matters needing attentions from variety selection,planting mode,rational fertilization,planting specifications and field management. | Hao FENG Zhengfeng WU Jiancai LIN Tianyi YU Yongmei ZHENG Xuewu SUN Pu SHEN Chengren SHI Caibin WANG | 2016 | Asian Agricultural Research2016，8，6： | 1 |
| 9 | Role of hydroxyl radical in modification of cell wall polysaccharides and aril breakdown during senescence of harvested longan fruit显示文摘 | Xuewu Duan Haiyan Zhang Dandan Zhang Jiangfeng Sheng Hetong Lin Yueming Jiang | 2011 | Food Chemistry2011，，1： | 1 |
| 10 | Effect of pure oxygen atmosphere on antioxidant enzyme and antioxidant activity of harvested litchi fruit during storage显示文摘 | Xuewu Duan Ting Liu Dandan Zhang Xinguo Su Hetong Lin Yueming Jiang | 2010 | Food Research International2010，，7： | 1 |
| 11 | Simulation of the mixing process in FCIs with hydrodynamic fragmentation model显示文摘Fuel Coolant Interactions (FCIs) are important issues in nuclear reactor severe accident analysis. In FCIs, fragmentation model of molten droplets is a key factor to estimate degree of possible damage. In this paper, the mixing process in FCIs is studied by the simulation of MIXA experiment with hydrodynamic fragmentation model. The result shows that hydrodynamic fragmentation model underestimates the fragmentation rate of high temperature molten droplets under the condition of low Weber numbers. It is concluded that models based on thermal fragmentation mechanism should be adopted to analyze the FCI process and its consequence. | LIN Qian CAO Xuewu | 2007 | Nuclear Science and Techniques2007，18，4： | 0 |
| 12 | End-to-End Joint Multi-Object Detection and Tracking for Intelligent Transportation Systems显示文摘Environment perception is one of the most critical technology of intelligent transportation systems(ITS).Motion interaction between multiple vehicles in ITS makes it important to perform multi-object tracking(MOT).However,most existing MOT algorithms follow the tracking-by-detection framework,which separates detection and tracking into two independent segments and limit the global efciency.Recently,a few algorithms have combined feature extraction into one network;however,the tracking portion continues to rely on data association,and requires com‑plex post-processing for life cycle management.Those methods do not combine detection and tracking efciently.This paper presents a novel network to realize joint multi-object detection and tracking in an end-to-end manner for ITS,named as global correlation network(GCNet).Unlike most object detection methods,GCNet introduces a global correlation layer for regression of absolute size and coordinates of bounding boxes,instead of ofsetting predictions.The pipeline of detection and tracking in GCNet is conceptually simple,and does not require compli‑cated tracking strategies such as non-maximum suppression and data association.GCNet was evaluated on a multivehicle tracking dataset,UA-DETRAC,demonstrating promising performance compared to state-of-the-art detectors and trackers. | Qing Xu Xuewu Lin Mengchi Cai Yu‑ang Guo Chuang Zhang Kai Li Keqiang Li Jianqiang Wang Dongpu Cao | 2023 | Chinese Journal of Mechanical Engineering2023，36，5： | 0 |
| 13 | Digital Twin Implementation of Autonomous Planning Arc Welding Robot System显示文摘Industrial robots are currently applied for ship sub-assembly welding to replace welding workers because of the intelligent production and cost savings.In order to improve the efficiency of the robot system,a digital twin system of welding path planning for the arc welding robot in ship sub-assembly welding is proposed in this manuscript to achieve autonomous planning and generation of the welding path.First,a five-dimensional digital twin model of the dual arc welding robot system is constructed.Then,the system kinematics analysis and calibration are studied for communication realization between the virtual and the actual system.Besides,a topology consisting of three bounding volume hierarchies(BVH)trees is proposed to construct digital twin virtual entities in this system.Based on this topology,algorithms for welding seam extraction and collision detection are presented.Finally,the genetic algorithm and the RRT-Connect algorithm combined with region partitioning(RRT-Connect-RP)are applied for the welding sequence global planning and local jump path planning,respectively.The digital twin system and its path planning application are tested in the actual application scenario.The results show that the system can not only simulate the actual welding operation of the arc welding robot but also realize path planning and real-time control of the robot. | Xuewu Wang Yi Hua Jin Gao Zongjie Lin Rui Yu | 2023 | Complex System Modeling and Simulation2023，3，3： | 0 |
| 14 | Position encoded asymmetrically clipped optical orthogonal frequency division multiplexing in visible light communications显示文摘A PE-ACO-OFDM(Position-Encoded Asymmetrically Clipped Optical Orthogonal Frequency Division Multiplexing)signaling scheme for intensity modulation and direct detection is introduced in this paper,where the anti-asymmetry characteristics of ACO-OFDM are exploited to improve the rate of data transmission.This is achieved by reducing the symbol duration of the ACO-OFDM signal,where only the first half of ACO-OFDM is used to transmit the ACO-OFDM data symbol after inverting its negative samples to positive ones.In addition,encoded ACO-OFDM samples are combined with every ACO-OFDM symbol to allow the receiver to identify the position of the inverted samples.Simulation results are introduced,and it is shown that the data rates of PE-ACO-OFDM improve by 33%compared with ACO-OFDM,when a 256-quadrature amplitude modulation scheme is considered as the encoded constellation order.It is also shown that the signal to noise ratio of the proposed PE-ACO-OFDM is higher by almost 1 dB compared with the traditional ACO-OFDM. | Osama Saied Zabih Ghassemlooy Xuan Tang Xuewu Dai Hoa Le Minh Bangjiang Lin | 2017 | Journal of Communications and Information Networks2017，2，4： | 0 |
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