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| 1 | Inhibitory effect of apolipoprotein A-I on matrix metalloproteinase-2 expression in vivo and in vitro显示文摘在现在的学习,我们调查了 apolipoprotein A-I 的效果(apoA -- 我) 在矩阵 metalloproteinase-2 (MMP-2 ) 上在 vivo 并且在 vitro 的表示。首先,我们检测了 apoA 的效果 -- 我在主动脉 MMP-2 上,激活 proliferator 的受体 /(PPAR /) , cyclooxygenase-2 (COX-2 ) ,和在动脉粥样硬化患者兔子的原子因素 kappa B (NF-B ) 表情用 immunohistochemical 方法建模的 peroxisome。结果证明 MMP-2, COX-2,和 NF-B 的表情在与 apoA 对待的动脉粥样硬化患者兔子的主动脉被减少 -- 我,当 PPAR / 表示被增加时。然后,我们选择了重要发炎房间,在 vitro 证明那些效果的巨噬细胞。巨噬细胞被划分成六个组并且与 apoA 的不同集中对待 -- 我, MMP-2 的 mRNA 表情, PPAR / ,和 COX-2 然后用 PPAR 的反向抄写的聚合酶链反应,和蛋白质表示被决定, NF-B 被西方的污点分析检测。在有教养的上层清液的 MMP-2 和 PPAR 的层次用连接酶的 immunosorbent 试金被决定。有趣地,在里面 vitro 结果类似于结果在里面 vivo 学习。在有 apoA 的孵化以后 -- 我为 24 h, MMP-2 的表情, COX-2,和 NF-B 被减少,当 PPAR / 表示被增加时。在他们在在 vivo 并且在 vitro 做匾马厩的进程的特别角色的考虑,我们推测 apoA 的禁止的效果 -- 我可以与 apoA 的效果在 MMP-2 表示上有一种靠近的关系 -- 我在 PPAR / , COX-2,和 NF-B 表达式上。尽管进一步的研究被需要澄清这些效果的内在的机制,我们的调查结果提供新奇卓见进 apoA 的反动脉粥样硬化患者匾破裂效果 -- 我。 | Weina Wang Xunlong Shi Yuan Yuan Haiyan Zhu Wei Zhou Hai Huang Meiqing Feng | 2013 | Acta Biochimica et Biophysica Sinica2013，45，3： | 2 |
| 2 | An integrated method for the rapid dewatering and solidification/stabilization of dredged contaminated sediment with a high water content显示文摘To more efficiently treat the dredged contaminated sediment(DCS)with a high water content,this study proposes an integrated method(called PHDVPSS)that uses the solidifying/stabilizing(S/S)agents and prefabricated horizontal drain(PHD)assisted by vacuum pressure(VP).Using this method,dewatering and solidification/stabilization can be carried out simultaneously such that the treatment time can be significantly shortened and the treatment efficacy can be significantly improved.A series of model tests was conducted to investigate the effectiveness of the proposed method.Experimental results indicated that the proposed PHDVPSS method showed superior performance compared to the conventional S/S method that uses Portland cement(PC)directly without prior dewatering.The 56-day unconfined compressive strength of DCS treated by the proposed method with GGBS-MgO as the binder is 12–17 times higher than that by the conventional S/S method.DCS treated by the PHDVPSS method exhibited continuous decrease in leaching concentration of Zn with increasing curing age.The reduction of Zn leachability is more obvious when using GGBS-MgO as the binder than when using PC,because GGBS-MgO increased the residual fraction and decreased the acid soluble fraction of Zn.The microstructure analysis reveals the formation of hydrotalcite in GGBS-MgO binder,which resulted in higher mechanical strength and higher Zn stabilization efficiency. | Hefu Pu Aamir Khan Mastoi Xunlong Chen Dingbao Song Jinwei Qiu Peng Yang | 2021 | Frontiers of Environmental Science & Engineering2021，15，4： | 2 |
| 3 | Biotransformation pathways of ginsenoside Rb1 to compound K by β-glucosidases in fungus Paecilomyces Bainier sp. 229显示文摘 | Qin Yan Wei Zhou XunLong Shi Pei Zhou DianWen Ju MeiQing Feng | 2010 | Process Biochemistry2010，，9： | 1 |
| 4 | Influence of processing medium on frictional wear properties of ball bearing steel prepared by laser surface melting coupled with bionic principles显示文摘 | Hong Zhou Chengtao Wang Qingchun Guo Jiaxiang Yu Mingxing Wang Xunlong Liao Yu Zhao Luquan Ren | 2010 | Journal of Alloys and Compounds2010，，2： | 1 |
| 5 | Houttuynia cordata polysaccharides alleviate ulcerative colitis by restoring intestinal homeostasis显示文摘Houttuynia cordata is traditionally used as phytoantibiotics for treating lung disease in China.Houttuynia cordata polysaccharides(HCPs)have been reported to alleviate influenza virus-induced intestinal and lung immune injury by regulating the gutlung axis.The present study aims to investigate the effects and mechanisms of HCPs on ulcerative colitis(UC).Male C57BL/6 mice were induced by dextran sodium sulfate(DSS)to establish the UC animal model.Our results showed that HCPs significantly reduced the weight loss and the shortening of colon length in colitis mice,and relieved the pathological damage of colon mucosa and inhibited the expression of pro-inflammatory cytokines such as TNF-α,IL-1β,IL-6,etc.It was suggested that HCPs could significantly improve DSS-induced colitis in mice.HCPs directly protected intestinal epithelial cells,ameliorated epithelial barrier dysfunction and cell apoptosis,which was also proved in H2O2 stimulated cell apoptosis model.HCPs inhibited inflammation in the colon,which was related to suppressing the infiltration of macrophages,inhibiting the expression of pro-inflammatory cytokines and proteins(TLR4,NF-κB),and restoring the dysfunction of Th17 and Treg cells.HCPs also restored the alteration of intestinal flora induced by DSS,increased the abundance of Firmicutes and Bacteroides,and reduced the abundance of Proteobacteria.This study confirmed the protective effect of Houttuynia cordata polysaccharide extracted from traditional Chinese medicine on ulcerative colitis,of which the mechanism was closely related to the maintenance of intestinal homeostasis(intestinal barrier,immune cells,and intestinal bacteria). | CEN Lifeng YI Tong HAO Yuanzhen SHI Chenchen SHI Xunlong LU Yan CHEN Daofeng ZHU Haiyan | 2022 | Chinese Journal of Natural Medicines2022，20，12： | 1 |
| 6 | Sodium vanadium oxides:From nanostructured design to high-performance energy storage materials显示文摘Developing high-capacity and low-cost cathode materials for metal-ion rechargeable batteries is the mainstream trend and is also the key to providing breakthroughs in making high-energy rechargeable batteries.Vanadium has a variety of valence states and can form a variety of vanadate structures.As a typical positive electrode material,vanadate has abundant ion adsorption sites,a unique“pillar”framework,and a typical layered structure.Therefore,it has the advantages of high specific capacity and excellent rate performance,possessing the prospect of being a large-capacity energy storage material.In this review,we focus on applications of sodium vanadium oxides(NVO)in electrical energy storage(EES)devices and summarize sodium vanadate materials from three aspects,including crystal structure,electrochemical performance,and energy storage mechanism.The recent progress of NVO-based highperformance energy storage materials along with nanostructured design strategies was provided and discussed as well.This review is intended to serve as general guidance for researchers to develop desirable sodium vanadate materials. | Yifan Dong Shuolei Deng Ziting Ma Ge Yin Changgang Li Xunlong Yuan Huiyun Tan Jing Pan Liqiang Mai Fan Xia | 2022 | Journal of Materials Science & Technology2022，，26： | 0 |
| 7 | Motion Predictions for a Vessel with Water on Deck显示文摘A numerical method is proposed for predicting six degree of freedom ship motion with green water on deck.Numerical results are presented which show the dynamic effect of water on deck on the ship motion. | Wei Luo 1) Renkang Wang 1) Jin Zhao 2) (Wuhan Transportation University 1) , Wuhan 430063,P.R.China) (Shen Zhen Xunlong Passenger Shipping Co.LTD 1) ,Shen Zhen 518097,P.R.China) | 1999 | 武汉理工大学学报(交通科学与工程版)1999，24，S1： | 0 |
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