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| 1 | Recent progress in Chinese fusion research based on superconducting tokamak configuration显示文摘Fusion energy is a promising source of clean energy,which could solve energy shortages and environmental pollution.Research into controlled fusion energy has been ongoing for over half a century.China has created a clear roadmap for magnetic confinement fusion development,where superconducting tokamaks will be used in commercial fusion reactors.The Experimental Advanced Superconducting Tokamak(EAST)is the world’s first fully superconducting tokamak with upper and lower divertors,which aims at longpulse,steady-state,H-mode operation,and 101-s H-mode discharge had been achieved.In 2007,China joined the International Thermonuclear Experimental Reactor(ITER)and became one of its seven members.Thirteen procurement packages are undertaken by China,covering superconducting magnets,power supplies,plasma-facing components(PFCs),diagnostics,etc.To bridge the gap between the ITER and fusion demonstration power plants(DEMOs),China is planning to build the Chinese Fusion Engineering Testing Reactor(CFETR)to demonstrate related technologies and physics models.The engineering design of the CFETR was completed in 2020,and Comprehensive Research Facilities for Fusion Technology(CRAFT)are being constructed to explore the key technologies used in the CFETR. | Jinxing Zheng Jinggang Qin Kun Lu Min Xu Xuru Duan Guosheng Xu Jiansheng Hu Xianzu Gong Qing Zang Zhihong Liu Liang Wang Rui Ding Jiming Chen Pengyuan Li Lei Xue Lijun Cai Yuntao Song | 2022 | The Innovation2022，3，4： | 3 |
| 2 | Overview of HL-2A Experiment Results显示文摘 | YANG Qingwei LIU Yong DING Xuantong YAN Longwen LIU Dequan XUAN Weiming CHEN Liaoyuan RAO Jun SONG Xianming CAO Zeng ZHANG Jinhua DUAN Xuru MAO Weicheng ZHOU Caipin PAN Chuanhong | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 1 |
| 3 | Divertor Experiments with MBI and Strong Gas Puffing on HL-2A显示文摘 | DUAN Xuru DING Xuantong YANG Qingwei YAN Longwen YAO Lianghua HONG Wenyu XUAN Weiming LIU Dequan CHEN Liaoyuan SONG Xianming ZHANG Jinhua CAO Zeng CUI Zhengying LI Wei LIU Yi PAN Yudong PAN Li ZHENG Yinjia ZHOU Yan MAO Weicheng LIU Yong 无 | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 0 |
| 4 | Long noncoding RNA GAS5 attenuates cigarette smoke-induced airway remodeling by regulating miR-217-5p/PTEN axis显示文摘Airway remodeling is a remarkable pathological characteristic of chronic obstructive pulmonary disease(COPD),and long noncoding RNAs have been demonstrated to participate in COPD development and pathogenesis.Here,we investigate the role of long noncoding RNA GAS5 in cigarette smoke(CS)-induced airway remodeling.GAS5 expression is significantly lower in lung tissues of CS-exposed mice than in tissues of control mice without exposure to CS.Forced GAS5 overexpression suppresses CS-induced airway inflammation and remodeling.GAS5 overexpression also inhibits CS extract-induced inflammatory-cytokine expression and fibroblast activation in vitro.Regarding the mechanism,GAS5 acts as a sponge of miR-217-5p,thereby increasing PTEN expression.MiR-217-5p overexpression and PTEN knockdown separately reverse the inhibitory effects of GAS5 overexpression on the inflammatory-cytokine expression and fibroblast activation.Collectively,these results suggest that GAS5 can suppress airway inflammation and fibroblast activation by regulating miR-217-5p/PTEN axis,which may help develop novel therapeutic strategies against COPD. | Yong Du Yi Ding Tianyun Shi Wei He Jingjing Feng Zhoufang Mei Xuru Chen Xintong Feng Xiaohua Zhang Zhijun Jie | 2022 | Acta Biochimica et Biophysica Sinica2022，54，7： | 0 |
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