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    题名 作者 年代 出处 被引量
1Effects of nonalcoholic fatty liver disease on the development of metabolic disorders显示文摘Fan, JG Li, F Cai, XB Peng, YD Ao, QH Gao, Y 2007中国生物学文摘2007,21,11:51
2胸痛中心认证与中国急性心肌梗死患者院内预后改善相关显示文摘中国胸痛中心(CPC)建设始于2010年,2016年7月胸痛中心总部正式成立。中国第一项有关CPC与急性心肌梗死(AMI)患者院内主要心血管事件之间关系的研究近期发表在J Am Heart Assoc上。该研究基于预先设计的中国心血管病医疗质量改善项目—急性冠脉综合征(CCC-ACS)项目中的全国注册登记数据,选取40家通过CPC认证医院的AMI患者15344例并通过倾向性评分匹配后共纳入CPC认证前、后入院患者各6700例,旨在评估CPC认证是否可以降低AMI患者入院7 d内复合心血管事件风险,并进一步证实CPC认证效果的持续性。FAN F LI Y ZHANG Y 本刊编辑部 2019实用心脑肺血管病杂志2019,27,10:27
3血管周围脂肪组织中的Bmal1通过血管紧张素原转录调控管理静息期血压显示文摘血管周围脂肪组织(perivascular adipose tissue,PVAT)围绕血管,构成了在生理条件下保持血管张力所需的脉管系统的独特的功能整体层。然而,关于PVAT与血压调节之间的关系的资料很少,包括其对昼夜血压变化的潜在作用。Chang L Xiong W Zhao X Fan Y Guo Y Garcia-Barrio M Zhang J Jiang Z Lin JD Chen YE 刘青 叶鹏 2018中华高血压杂志2018,26,2:23
4Proteomic analysis of human ovaries from normal and polycystic ovarian syndrome显示文摘Ma,X Fan,L Meng,Y Hou,Z Mao,YDL Wang,W Ding,W Liu,JY 2007南京医科大学学报(自然科学版)2007,27,11:20
5Reduced Macular Vascular Density in Myopic Eyes显示文摘Hua Fan Hao-Yu Chen Hong-Jie Ma Zheng Chang Hai-Quan Yin Danny Siu-Chun Ng Carol Y Cheung Shan Hu Xiang Xiang Shi-Bo Tang Shuang-Nong Li 2017Chinese Medical Journal2017,,4:17
6Efficient new method for extraction and isolation of three flavonoids from Patrinia villosa Juss. by supercritical fluid extraction and high-speed counter-current chromatography显示文摘Peng J Fan G Chai Y Wu Y 2006第二军医大学学报2006,27,6:16
7Factors predicting survival in patients with proximal gastric carcinoma involving the esophagus显示文摘AIM:To investigate the clinicopathologic features which predict surgical overall survival in patients with proximal gastric carcinoma involving the esophagus (PGCE).METHODS:Electronic pathology database established in the Department of Pathology of the Nanjing Drum Tower Hospital was searched for consecutive resection cases of proximal gastric carcinoma over the period from May 2004 through July 2009.Each retrieved pathology report was reviewed and the cases with tumors crossing the gastroesophageal junction line were selected as PGCE.Each tumor was re-staged,following the guidelines on esophageal adenocarcinoma,according to the 7th edition of the American Joint Commission on Cancer Staging Manual.All histology slides were studied along with the pathology report for a retrospective analysis of 13 clinicopathologic features,i.e.,age,gender,Helicobacter pylori (H.pylori ) infection,surgical modality,Siewert type,tumor Bormann's type,size,differentiation,histology type,surgical margin,lymphovascular and perineural invasion,and pathologic stage in relation to survival after surgical resection.Prognostic factors for overall survival were assessed with uniand multi-variate analyses.RESULTS:Patients' mean age was 65 years (range:47-90 years).The male:female ratio was 3.3.The 1-,3and 5-year overall survival rates were 87%,61% and 32%,respectively.By univariate analysis,age,male gender,H.pylori ,tumor Bormann's type,size,histology type,surgical modality,positive surgical margin,lymphovascular invasion,and pT stage were not predictive for overall survival;in contrast,perineural invasion (P = 0.003),poor differentiation (P = 0.0003),> 15 total lymph nodes retrieved (P = 0.008),positive lymph nodes (P = 0.001),and distant metastasis (P = 0.005) predicted poor post-operative overall survival.Celiac axis nodal metastasis was associated with significantly worse overall survival (P = 0.007).By multivariate analysis,≥ 16 positive nodes (P = 0.018),lymph node ratio > 0.2 (P = 0.003),and overall pathologic stage (P = 0.002) were independent predictors for poor overall survival after resection.CONCLUSION:Patients with PGCE showed worse overall survival in elderly,high nodal burden and advanced pathologic stage.This cancer may be more accurately staged as gastric,than esophageal,cancer.Yi-Fen Zhang Jiong Shi Hui-Ping Yu An-Ning Feng Xiang-Shan Fan Gregory Y Lauwers Hiroshi Mashimo Jason S Gold Gang Chen Qin Huang 2012World Journal of Gastroenterology2012,18,27:12
8Ex vivo expansion of hematopoietic stem cells derived from umbilical cord blood in rotating wall vessel显示文摘Liu Y Liu T Fan X Ma X Cui Z 2006中国生物学文摘2006,20,5:11
9中国卫生人力资源:数量、质量和分布显示文摘在本文中,我们从数量、质量和分布的角度对中国现有的卫生人力资源进行了分析。与绝大多数国家不同,2005年中国拥有的医生总数大于护士总数——注册的执业医师和执业助理医师总数达190多万,注册的护士总数为140多万。城市地区的医生密度是农村地区的2倍多,而城市地区护士的密度是农村地区的3倍多。中国大多数医生(67.2%)和护士(97.5%)所接受的教育仅为大专或中专水平。自1998年以来,中国的医学卫生教育事业有了很大的发展,医学院校不断扩招又导致了卫生人员供过于求的局面。Sudhir Anand Victoria Y Fan Junhua Zhang Lingling Zhang Yang Ke Zhe Dang Lincoln C Chen 2009世界临床医学2009,3,1:9
10Association between adiponectin concentrations and diabetic retinopathy in patients with type 2 diabetes: a meta analysis显示文摘Fan XH Wu QH Hao YH Ning N Kang Z Cui Y Liu RH 2014Chinese Medical Journal2014,,4:8
11基于发泡机种类的泡沫沥青及其混合料性能研究显示文摘针对3种常见的发泡机(Wirtgen发泡机、InstroTek发泡机和PTI发泡机),借助非接触式试验装置,采用ERmax、PI和SAI指标评价不同发泡机对沥青发泡性能的影响,在此基础上研究了温拌泡沫沥青混合料的和易性、覆盖性和力学性能。试验结果表明:Wirtgen发泡机制备的泡沫沥青膨胀率最大,泡沫稳定性最好,其次为InstroTek发泡机和PTI发泡机;借助最大剪应力和CI值,建议Wirtgen、InstroTek和PTI发泡剂制备泡沫沥青的最佳用水量为2.0%、2.0%和5.0%;与热拌沥青混合料相比,不同种类发泡机制备的泡沫沥青混合料回弹模量相当,但水稳定性不足,抗车辙能力降低,尤其是PTI发泡机制备的泡沫沥青混合料抗车辙能力最差。赵宾 申爱琴 郭寅川 Fan Y Arámbulamercado E Newcomb D 2018中外公路2018,38,2:6
12白细胞介素8/β连环蛋白介导成釉细胞瘤的上皮-间充质转化显示文摘Zhang J,Wang Y,Fan C,et al.Interleukin-8/β-catenin mediates epithelial-mesenchymal transition in ameloblastoma.Oral Dis,2019 Aug.目的:上皮-间充质转化(EMT)在牙发育和肿瘤侵袭中发挥重要作用。赵泽亮 Zhang J Wang Y Fan C 2019中国口腔颌面外科杂志2019,17,5:6
13笋芽顶端分生组织在竹秆横切面形态形成中的作用与机制研究显示文摘竹秆的横切面主要由表皮、皮层、维管组织、基本组织及髓腔(早期为髓组织)组成。这些组织均由笋芽茎顶端分生组织分化发育而来,且其在生长发育过程中促使了竹秆横切面形态(本文特指:竹秆横切面外轮廓形状、围度及壁-腔结构)的形成。然而,人们对于这一生长发育过程的生物学机制知之甚少。本研究利用解剖学、数学模拟等方法,对 20 种具不同秆径竹种的笋芽顶端分生组织进行了分析。研究结果发现,笋芽顶端分生组织指状形态的维持是竹子产生圆柱形竹秆的基础;在顶端分生组织细胞数目增加的同时,线性增加原体细胞数目应是竹子在演化过程中产生大径竹秆且保持规则壁-腔结构的方式。进一步通过研究一个竹壁增厚且壁-腔架构紊乱的稳定变异体———实肚竹( Phyllostachys nidularia f. farcta)发现,其笋芽顶端分生组织细胞数目减少且原体/原套细胞数比值降低使其产生了高比例的壁组分组织(指基本分生组织与肋状分生组织)与低比例的髓组织。上述 2 种组织的比例失衡,使得实肚竹笋芽在后续发育中壁组分组织随机挤入到了髓组织中,最终形成了实肚竹异常的竹秆横切面形态(竹壁多样化增厚且壁-腔结构紊乱)。此外,相对较小的顶端分生组织,使得实肚竹笋芽产生了较少的内源激素,如其生长素含量仅约为其原种篌竹的 67. 5%,各细胞分裂素含量也显著低于篌竹笋芽。转录组分析进一步发现,在实肚竹笋芽中与激素及代谢相关的功能基因呈显著下调表达。这些生理与分子变化最终导致了实肚竹竹秆矮化、秆径减小且生物量降低。本论文的研究结果为研究竹秆横切面发育提供了一个重要的视角,同时也为实肚竹厚壁茎秆的形成提出了一个合理的机制。Wang Y Sun X Ding Y Fei Z Jiao C Fan M Yao B Xin P Chu J Wei Q 王雨珺 魏强 2019世界竹藤通讯2019,17,3:5
14寨卡病毒感染胎儿脑组织小神经胶质细胞并诱发炎症显示文摘卷土重来的寨卡病毒震惊了世界,巴西小头畸形的报道持续增加。寨卡病毒能够感染人类神经前体细胞,损害大脑生长。但目前尚缺乏寨卡病毒感染人类胎儿脑组织的直接证据。作者等对9份因寨卡病毒感染而终止妊娠的胎儿脑细胞标本进行了研究。Lum FM Low DK Fan Y 吴俊珍 刘笑芬 2017中国感染与化疗杂志2017,17,5:5
15母亲妊娠期焦虑抑郁对孩子应激性心率及血压的影响显示文摘心理障碍,包括焦虑和抑郁在妊娠期间十分常见。该研究目的在于确定母亲的这些心理障碍是否会对后代的心血管反应产生影响。方法:对231名孕妇的心理状态进行评定,在其后代(n=216)7~9岁时进行视频压力反应测试。测定静息时、观看压力视频时和恢复期的心率及血压水平。刘莉 叶鹏 Fan F Zou Y Tian H Zhang Y Zhang J Ma X Meng Y Yue Y Liu K Dart AM 2015中华高血压杂志2015,23,6:5
16Association of polymorphisms in the vascular endothelial growth factor gene and its serum levels with diabetic retinopathy in Chinese patients with type 2 diabetes: A cross-sectional study显示文摘Fan XH Wu QH Li Y Hao YH Ning N Kang Z Cui Y Liu RH 2014Chinese Medical Journal2014,,4:4
17Wiener filtering and LMS algorithm of periodic nonuniformly sampled stochastic sequence显示文摘FAN L Y 1995IEE Electronics Letters1995,31,20:3
18Stereoselective pharmacokinetics of tetrahydropalmatine after oral administration of (-)-enantiomer and the racemate显示文摘Hong Z Fan G Chai Y Yin X Wu Y 2005第二军医大学学报2005,26,10:3
19Estrogen provides neuroprotection against activated microglia-induced dopaminergic neuronal injury through both estrogen receptor-alpha and estrogen receptor-beta in microglia显示文摘Liu X Fan XL Zhao Y Luo GR Li XP Li R Le WD 2006中国生物学文摘2006,20,10:2
20Cloning and identification of an angiostatic molecule IP-10/crg-2显示文摘AIM To obtain human and murine cDNAsencoding IFN--y inducible protein 10 (lP--10) andcytokine responsive gene--2 (Crg-2).METHODS The encoding genes of lP-10 and Crg2 were amplified by RT--PCR from Cultured humanfibroblast cells and Balb/ c mouse liver treatedby IFN-y and TNF-a, respectively, and clonedinto plasmids of PUC19 and PGEM3Zf(+ ).RESULTS The nucleotide sequences ot theamplified DNA were confirmed by endonucleasesdigestion and sequencing.CONCLUSION Recombinant lP-10/ crg--2 geneclones with 306 hp and 314 hp inserts wereestablished for further research on biologicalactivities and ligands of hiP-10/mCrg--2.Liu ZG Yang JH An HZ Wang HY He FT Han ZY Han Y Wu HP Xiao B Fan DM 1999World Journal of Gastroenterology1999,5,3:2
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