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| 1 | Mining intrinsic information of convalescent patients after suffering coronavirus disease 2019 in Wuhan显示文摘OBJECTIVE:To summarize the potential characteristics of convalescent patients with coronavirus disease 2019(COVID-19)in China based on emerging clinical tongue data and guide the treatment and recovery of COVID-19 patients from the perspective of Traditional Chinese Medicine tongue diagnosis.METHODS:In this study,we developed and validated radiomics-based and lab-based methods as a novel approach to provide individualized pretreatment evaluation by analyzing different features to mine the orderliness behind tongue data of convalescent patients.In addition,this study analyzed the tongue features of convalescent patients from clinical tongue qualitative values,including thick and thin,fur,peeling,fat and lean,tooth marks and cracked,and greasy and putrid fur.RESULTS:We included 2164 tongue images in total(34%from day 0,35.4%from day 14 and 30.6%from day 28)from convalescent patients.The significance results are shown as follows.Firstly,as the recovery time prolongs,the L average values of tongue and coat decrease from 60.21 to 57.18 and from 60.06 to 57.03 respectively.Secondly,the decrease of abnormality rate of tongue coat,included greasy tongue fur,putrid fur,teeth-mark,thick-thin fur,are of significant statistical difference(P<0.05).Thirdly,the average value of gray-level cooccurrence matrices increases from 0.173 to 0.194,the average value of entropy increases from 0.606 to 0.665,the average value of inverse difference normalized decrease from 0.981 to 0.979,and the average value of dissimilarity decrease from 0.1576 to 0.1828.The details of other radiomics features are describe in results section.CONCLUSIONS:Our experiment shows that patients in different recovery periods have a relationship with quantitative values of tongue images,including L color space of the tongue and coat radiomics features analysis.This relationship can help clinical doctors master the recovery and health of patients as soon as possible and improve their understanding of the potential mechanisms underlying the dynamic changes and mechanisms underlying COVID-19. | YAN Shixing LüYi LIU Ziqing REN Meng HE Haiyang XIAO Li GUO Feng PENG Miao LI Xiaoxia WANG Yong XU Xi YANG Tao SHAO Zuoyu HUANG Jingjing XIAO Mingzhong | 2022 | Journal of Traditional Chinese Medicine2022，42，2： | 1 |
| 2 | Indocyanine Green Angiographic and Multifocal Electroretinographic Features in the Diffuse and Regional From of Bietti's Cystalline Retinopathy显示文摘Prpose: To observe different features of indocyanine green angiography(ICGA) andtifocal electroretinography (ERG) in the diffuse and regional type of Bieti′sc stalline retinopathy (BCR). Thods: ICGA and the multifocal ERG were performed in two cases of the diffuse andregional type of BCR respectively. These data were compared with fluoresceinangiography (FA), standard Ganzfeld ERG, and visual field testing. Results: In the regional case, ICGA revealed reduced perfusion of the choroidalcirculation in the early phase and multiple hypofluorescent spots in the posterior pole in the late phase, due to choriocapillaris filling defect; the extent of choroiocapillaris losswas shown in early phase of ICGA and there were multifocal hyperfluorescent dotssurrounding hypofluorescent spots in late phase in the diffuse case. The multifocal ERGshowed that the central responses were markedly depressed, corresponding to the visualfield defects, while the findings of Ganzfeld ERG were normal in the regional BCR;however, both the multifocal ERG and Ganzfeld ERG were severely subnormal in thediffuse case.Conclusions: The features of ICGA and multifocal ERG are different between the diffuseand regional BCR. In the meantime, the two tools are also useful to differentiate the typeand assess the extentof evolution in BCR. | Libin Jiang, Feng Wen, Lezheng Wu, Hong Yan, Shixing HuZhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China | 2002 | Eye Science2002，18，1X： | 0 |
| 3 | Experimental study of the dynamic mechanical responses and failure characteristics of coal under true triaxial confinements显示文摘Investigations on the dynamic mechanical properties and failure mechanisms of coal under in-situ stress is essential for the prevention of dynamic disasters in deep coal mines.Thus,a modified true triaxial Hopkinson bar was employed to explore the dynamic mechanical behaviors of coal at different confining pressures(0–20 MPa)and strain rates(40–220 s^(-1)).The results show that the dynamic peak stress is positively correlated with lateral static pre-stressσy andσz,but negatively correlated with axial static prestressσx.At approximate strain rates,increasing the lateral static pre-stress facilitates increasing the dynamic peak stress,but the minimum lateral static pre-stress is the primary factor limiting a significant increase in dynamic peak stress of coal.Furthermore,the dynamic differential stress is linearly related to the logarithm of strain rate,and the peak strain varies linearly with strain rate.However,there is no significant correlation between confining pressure and peak strain.Moreover,X-ray CT images and photographic fracture observations of coal samples show the failure patterns under uniaxial and triaxial conditions are splitting failure and shear failure,respectively.The device provides a viable approach for fully comprehending the dynamic mechanical behaviors of rock-like material in complex stress conditions. | Zhanguo Ma Pengfei Yan Shixing Cheng Peng Gong Fuzhou Qi Jianguo Wang | 2023 | International Journal of Mining Science and Technology2023，33，6： | 0 |
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