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| 1 | Role of microbial dysbiosis in the pathogenesis of esophageal mucosal disease:A paradigm shift from acid to bacteria?显示文摘Genomic sequencing,bioinformatics,and initial speciation(e.g.,relative abundance)of the commensal microbiome have revolutionized the way we think about the“human”body in health and disease.The interactions between the gut bacteria and the immune system of the host play a key role in the pathogenesis of gastrointestinal diseases,including those impacting the esophagus.Although relatively stable,there are a number of factors that may disrupt the delicate balance between the luminal esophageal microbiome(EM)and the host.These changes are thought to be a product of age,diet,antibiotic and other medication use,oral hygiene,smoking,and/or expression of antibiotic products(bacteriocins)by other flora.These effects may lead to persistent dysbiosis which in turn increases the risk of local inflammation,systemic inflammation,and ultimately disease progression.Research has suggested that the etiology of gastroesophageal reflux disease-related esophagitis includes a cytokine-mediated inflammatory component and is,therefore,not merely the result of esophageal mucosal exposure to corrosives(i.e.,acid).Emerging evidence also suggests that the EM plays a major role in the pathogenesis of disease by inciting an immunogenic response which ultimately propagates the inflammatory cascade.Here,we discuss the potential role for manipulating the EM as a therapeutic option for treating the root cause of various esophageal disease rather than just providing symptomatic relief(i.e.,acid suppression). | Steve M D'Souza Kevin Houston Lauren Keenan Byung Soo Yoo Parth J Parekh David A Johnson | 2021 | World Journal of Gastroenterology2021，27，18： | 8 |
| 2 | Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression显示文摘 | Yoo Byoung Kwon Emdad Luni Su Zao-zhong Villanueva Augusto Chiang Derek Y Mukhopadhyay Nitai D Mills Alan Scott Waxman Samuel Fisher Robert A Llovet Josep M Fisher Paul B Sarkar Devanand | 2009 | Journal of Clinical Investigation2009，，3： | 2 |
| 3 | Methods of Operative Fixation of the Acromio-Clavicular Joint: A Biomechanical Comparison显示文摘 | Alison J McConnell Daniel J Yoo Rad Zdero Emil H Schemitsch Michael D McKee | 2007 | Journal of Orthopaedic Trauma2007，，4： | 2 |
| 4 | Effect of cervical spine motion on neuroforamina dismensions显示文摘 | Yoo Yu Bayley J Zou D | 1992 | Spine1992，17，： | 2 |
| 5 | Preparation of mesostructured barium sulfate with high surface area by dispersion method and its characterization显示文摘 | NAGARAJA B M ABIMANYU H JUNG K D YOO K S | 2007 | J Colloid Interf Sci2007，316，： | 1 |
| 6 | The Impact of Marketing - induced Versus Word - of - mouth Customer Acquisition on Customer Equity Growth 显示文摘 | Villanueva J Yoo S Hanssens D M | 2008 | Journal of Marketing Research2008，45，1： | 1 |
| 7 | Selection of a Streptococcus equi mutant and optimization of culture conditions for the production of high molecular weight hyaluronic acid显示文摘 | KIM J H YOO S J OH D K | 1996 | Enzyme Microb Tech1996，19，6： | 1 |
| 8 | Toroidally- wound self-bearing BLDC motor with lorentz force 显示文摘 | LEE Hak-In YOO Seong-Yeol NOH Myounggyu D | 2010 | IEEE Transactions on Magnetics2010，46，6： | 1 |
| 9 | Force-displacement model foranalysis of pulsed-GMAW显示文摘 | Arif N Lee J H Yoo C D | 2009 | Journal of Physics D:AppliedPhysics2009，42，3： | 1 |
| 10 | Changes in the microstructure and hydrogen storage properties of Ti℃r-V alloys by ball milling and heat treatment 显示文摘 | CHO S W YOO J H CHANG H K KIM W B KIL D S AHN J G | 2011 | Journal of Alloys and Compounds2011，509，18： | 1 |
| 11 | 查看详情显示文摘 | (e) Kim D C Lee Y R Yang B -S Shin K J Kim D J Chung B Y Yoo K H | | 0，，： | 1 |
| 12 | Electropolymerization mechanism for poly (o-phenylenediamine) (ppd) and its electrocatalytic behavior for O2 reduction显示文摘 | Jang D H Yoo Y S Oh S M | | 0，，05： | 1 |
| 13 | Prospective trial of synchronous bevacizumab, erlotinib,and concurrent chemoradiation in locally ad- vanced head and neck cancer显示文摘 | YOO D S KIRKPATRICK J P CRACIUNESCU O | 2012 | Clin Cancer Res2012，18，： | 1 |
| 14 | Development o{ thermoregu 显示文摘 | SHIN Y YOO D I SON K | 2005 | Journal of Applied Polymer Science2005，97，3： | 1 |
| 15 | Underdetermined blind source separation based on subspace representation显示文摘 | KIM S G YOO C D | 2009 | IEEE Transactions on Signal Processing2009，57，7： | 1 |
| 16 | Electrical conduction through poly(dA)-poly(dT) and poly(dG)-poly(dC) DNA polecules显示文摘 | Yoo K H Ha D H Lee J O | 2001 | Phys Rev Lett2001，87，19： | 1 |
| 17 | Gradual shot boundary detection using localized edge blocks 显示文摘 | Yoo H W Ryoo H J Jang D S | 2006 | Journal of Multimedia Tools and Application2006，28，3： | 1 |
| 18 | Interaction of NG2 ( + ) glial progenitors and microglia/macrophages from the injured spinal cord显示文摘 | Wu J Yoo S Wilcock D | 2010 | Glia2010，58，4： | 1 |
| 19 | 查看详情显示文摘 | Kim S D Baek S C Lee Y J Jun K W Kim M J Yoo I S | | 0，，： | 1 |
| 20 | The iliotibial band in acute knee trauma: patterns of injury on MR imaging显示文摘 | Mansour P Yoo P McKean D et al | 2014 | Skeletal Radiol2014，43，10： | 1 |
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