|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Evaluation of magnifying colonoscopy in the diagnosis of serrated polyps显示文摘AIM:To elucidate the colonoscopic features of serrated lesions of the colorectum using magnifying colonoscopy.METHODS:Broad division of serrated lesions of the colorectum into hyperplastic polyps(HPs),traditional serrated adenomas(TSAs),and sessile serrated adenomas/polyps(SSA/Ps) has been proposed on the basis of recent molecular biological studies.However,few reports have examined the colonoscopic features of these divisions,including magnified colonoscopic findings.This study examined 118 lesions excised in our hospital as suspected serrated lesions after magnified observation between January 2008 and September 2011.Patient characteristics(sex,age),conventional colonoscopic findings(location,size,morphology,color,mucin) and magnified colonoscopic findings(pit pattern diagnosis) were interpreted by five colonoscopists with experience in over 1000 colonoscopies,and were compared with histopathological diagnoses.The pit patterns were categorized according to Kudo's classification,but a more detailed investigation was also performed using the subclassification [type Ⅱ-Open(type Ⅱ-O),type Ⅱ-Long(type Ⅱ-L),or type Ⅳ-Serrated(type Ⅳ-S)] proposed by Kimura T and Yamano H.RESULTS:Lesions comprised 23 HPs(23/118:19.5%),39 TSAs(39/118:33.1%:with cancer in one case),50 SSA/Ps(50/118:42.4%:complicated with cancer in three cases),and six others(6/118:5.1%).We excluded six others,including three regular adenomas,one hamartoma,one inflammatory polyp,and one juvenile polyp for further analysis.Conventional colonoscopy showed that SSA/Ps were characterized as larger in diameter than TSAs and HPs(SSA/P vs HP,13.62 ± 8.62 mm vs 7.74 ± 3.24 mm,P < 0.001;SSA/Ps vs TSA,13.62 ± 8.62 mm vs 9.89 ± 5.73 mm,P < 0.01);common in the right side of the colon [HPs,30.4%(7/23):TSAs,20.5%(8/39):SSA/P,84.0%(42/50),P < 0.001];flat-elevated lesion [HPs,30.4%(7/23):TSAs,5.1%(2/39):SSA/Ps,90.0%(45/50),P < 0.001];normal-colored or pale imucosa [HPs,34.8%(8/23):TSAs,10.3%(4/39):SSA/Ps,80%(40/50),P < 0.001];and with large amounts of mucin [HPs,21.7%(5/23):TSAs,17.9%(7/39):SSA/Ps,72.0%(36/50),P < 0.001].In magnified colonoscopic findings,17 lesions showed either type Ⅱ pit pattern alone or partial type Ⅱ pit pattern as the basic architecture,with 14 HPs(14/17,70.0%) and 3 SSA/Ps.Magnified colonoscopy showed the type Ⅱ-O pit pattern as characteristic of SSA/Ps [sensitivity 83.7%(41/49),specificity 85.7%(54/63)].Cancer was also present in three lesions,in all of which a type Ⅵ pit pattern was also present within the same lesion.There were four HPs and four TSAs each.The type Ⅳ-S pit pattern was characteristic of TSAs [sensitivity 96.7%(30/31),specificity 89.9%(72/81)].Cancer was present in one lesion,in which a type Ⅵ pit pattern was also present within the same lesion.In our study,serrated lesions of the colorectum also possessed the features described in previous reports of conventional colonoscopic findings.The pit pattern diagnosis using magnifying colonoscopy,particularly magnified colonoscopic findings using subclassifications of surface architecture,reflected the pathological characteristics of SSA/Ps and TSAs,and will be useful for colonoscopic diagnosis.CONCLUSION:We suggest that this system could be a good diagnostic tool for SSA/Ps using magnifying colonoscopy. | Shinya Ishigooka Masahito Nomoto Nobuyuki Obinata Yoshichika Oishi Yoshinori Sato Satoko Nakatsu Midori Suzuki Yoshiko Ikeda Tadateru Maehata Tomoaki Kimura Yoshiyuki Watanabe Takashi Nakajima Hiro-o Yamano Hiroshi Yasuda Fumio Itoh | 2012 | World Journal of Gastroenterology2012，18，32： | 11 |
| 2 | Insulin-like growth factor-1, IGF binding protein-3, and the risk of esophageal cancer in a nested case-control study显示文摘AIM To assess the relationship between serum levels of insulin-like growth factor-1(IGF1)/IGF-binding protein-3(IGFBP3)and the risk of esophageal carcinoma.METHODS We assessed the relationship between the serum levels of these molecules and the risk of esophageal cancer in a prospective,nested case-control study of participants from the Japan Collaborative Cohort Study.A baseline survey was conducted from 1988 to 1990.Of the 110585 enrolled participants,35%donated blood samples.Those who had been diagnosed with esophageal cancer were considered cases for nested case-control studies.A conditional logistic model was used to estimate odds ratios for the incidence of esophageal cancer associated with serum IGF1 and IGFBP3 levels.RESULTS Thirty-one cases and 86 controls were eligible for the present assessment.The molar ratio of IGF1/IGFBP3,which represents the free and active form of IGF1,was not correlated with the risk of esophageal carcinoma.A higher molar difference between IGFBP3and IGF1,which estimates the free form of IGFBP3,was associated with a decreased risk of esophageal carcinoma(P=0.0146),and people in the highest tertile had the lowest risk(OR=0.107,95%CI:0.017-0.669).After adjustment for body mass index,tobacco use,and alcohol intake,the molar difference of IGFBP3-IGF1 was inversely correlated with the risk of esophageal carcinoma(P=0.0150).CONCLUSION The free form of IGFBP3,which is estimated by this molar difference,may be inversely associated with esophageal cancer incidence. | Yasushi Adachi Masanori Nojima Mitsuru Mori Kentaro Yamashita Hiro-o Yamano Hiroshi Nakase Takao Endo Kenji Wakai Kiyomi Sakata Akiko Tamakoshi | 2017 | World Journal of Gastroenterology2017，23，19： | 4 |
| 3 | Typical gastroduodenal endoscopic findings in a Crohn's disease patient in remission stage显示文摘A 39-year-old patient with Crohn's disease (CD) was referred to our hospital for maintenance treatment of CD.He was diagnosed as having CD of the small and large intestines at 32 years old.He underwent partial resection of the ileum at 35 years old because of ileal perforation.He had received enteral nutritional supplement (1200 kcal/d) and metronidazole preparation (500 mg/d),and was in remission Crohn's disease activity index 73.We performed a routine gastroduodenal endoscopic examination,which revealed the representative endoscopic findings of gastroduodenal lesions in CD,namely,bamboo-joint-like appearance of the gastric body and cardia and a notched sign in the duodenum.These findings were clearly observed by using indigo carmine dye spraying.In our patient,typical gastroduodenal findings were observed even in the remission stage,suggesting that these findings would contribute to the early diagnosis of CD not only in the active stage but also during remission. | Masahiro Iizuka Taku Harada Hiro-o Yamano Takeshi Etou Shiho Sagara | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，3： | 2 |
| 4 | JGES guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection显示文摘 | Shinji Tanaka Hiroshi Kashida Yutaka Saito Naohisa Yahagi Hiroo Yamano Shoichi Saito Takashi Hisabe Takashi Yao Masahiko Watanabe Masahiro Yoshida Shin‐ei Kudo Osamu Tsuruta Ken‐ichi Sugihara Toshiaki Watanabe Yusuke Saitoh Masahiro Igarashi Takashi Toyon | 2015 | Digestive Endoscopy2015，，4： | 2 |
| 5 | Eicosanoids mediate induction of immune genes in the fat body of silkworm, Bombyx mori 显示文摘 | Yamano Y Inoue K | 1997 | FEBS-Letters1997，419，1： | 1 |
| 6 | Effective activationmethod with A23187 and puromycin to pro- duce haploid parthengenones from freshly ovulated mouse oocytes显示文摘 | Nakasaka H Yamano S Hinokio K | 2000 | Zygore2000，8，3： | 1 |
| 7 | Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury显示文摘 | ABEMATSU M TSUJIMURA K YAMANO M | 2010 | J Clin Invest2010，120，9： | 1 |
| 8 | Idiopathic spinal cord herniation in the thoracic spine as a cause of intractable leg pain:case report and review of the literature显示文摘 | Sasaoka R Nakamura H Yamano Y | 2003 | J Spinal Disord Tech2003，16，3： | 1 |
| 9 | Hyperspectral identification of grassland vegetation in Xilinhot, Inner Mongolia, China显示文摘 | Yamano H Chen J Tamura M | 2001 | International Journal of Remote Sensing2001，24，15： | 1 |
| 10 | Antibodies block capacitation in human spermatozoa显示文摘 | Myogo K Yamano S | 2001 | Arch Androl2001，47，2： | 1 |
| 11 | Protective effects of a PAF receptor antagonist and a neutrophil elastase inhibitor on multiple organ failure induced by cerulein plus lipopolysaccharide in rats显示文摘 | Yamano M Uemda M Miyata K | 1998 | Naunyn Schmiedebergs Arch Pharmacol1998，358，： | 1 |
| 12 | ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells显示文摘 | Yamano G Funahashi H Kawanami O | 2001 | FEBS Lett2001，508，2： | 1 |
| 13 | Three-dimensional transoesophageal echocardiography in detailed evaluation of cortriatriatum显示文摘 | Iwamura Y Yamano T Sakai T | 2011 | Eur J Echocardiogr2011，12，6： | 1 |
| 14 | Styrene-methyl acrylate copolymers and acrylate homhpolymers in solution 显示文摘 | MATSUDA H YAMANO K INAGAKI H | 1969 | J Polym Sci A-21969，7，： | 1 |
| 15 | Fertilization failure and oocyte activation显示文摘 | Yamano S Nakagawa K Nakasaka H | 2000 | J Med Invest2000，47，1： | 1 |
| 16 | Replantation of the amputated distal part of the fingers显示文摘 | Yamano Y | 1985 | J Hand Surgery1985，10，2： | 1 |
| 17 | Rate of swelling of sodium polyacrylate显示文摘 | Ogawa I Yamano H Migagawa K | 1993 | J Appl PolymSci1993，47，： | 1 |
| 18 | Expression of salmon growth hormone in the cyanobacterium A gmenell urn quadruplicat urn 显示文摘 | Kawata Y Yamano N Kojima H | 1991 | Biotechnol Lett1991，13，： | 1 |
| 19 | The role of thyroid hormone in fish development with reference to aquaculture 显示文摘 | YAMANO K | 2005 | JARQ2005，39，3： | 1 |
| 20 | Diagnosis of primary versus me- tastatic ovarian adenocarcinoma using p53 gene mutation analysis 显示文摘 | Yamano T Morii E Arai I | 2010 | Int J Clin Oncol2010，15，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员