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| 1 | Effect of Eel head protein hydrolysates on the denaturation of grass carp surimi during frozen storage显示文摘 | Yanan Z Li Z Hua L | 2012 | Procedia Engineering2012，37，： | 1 |
| 2 | De novo acute megakaryoblastic leukemia with p210 BCR/ABL and t(1;16) translocation but not t(9;22) Ph chromosome显示文摘 | Min X Na Z Yanan L | 2011 | J Hernatol Oncol2011，4，1： | 1 |
| 3 | Factors inflencingapical node metastasis in colorectal cancer patients treated withlaparoscopic radical resection with D3 lymphadenectomy:results from two centers in China 显示文摘 | Hongyuan C Yanan W Hao L | 2015 | Surg Today2015，45，： | 1 |
| 4 | The relationship between oil price shocks and China' s macro-economy: An empirical analysis显示文摘 | Du L Yanan H Wei C | 2010 | Energy Policy2010，38，8： | 1 |
| 5 | Interaction of the Cyto- chrome P4501A2, SULT1A1 and NAT gane polymorphisms with smoking and dietary mutagen intake in modification of the risk of pan- creatic cancer显示文摘 | Hideo Suzuki Jeffrey S Morris Yanan Li Mark A Doll David W Hein Jun Liu Li ]ian Manal M Hassan Rena S Day Melissa L Bondy James L Abbruzzese and Donghui Li | 2008 | Carcinogenesis2008，29，6： | 1 |
| 6 | Nanomaterials for X -ray imaging : gold nanoparticle enhancement of X - ray scatter imaging of hepato- cellular carcinoma 显示文摘 | Rand D Ortiz V Yanan L | 2011 | Nano Lett2011，11，： | 1 |
| 7 | Polymorphisms of XRCC1 gene and risk of gastric cardiac adenocarcinoma显示文摘 | Yan L Yanan D Donglan S | 2009 | Dis Esophagus2009，22，5： | 1 |
| 8 | An Ant Colony Algorithm for Both Robust and Global Optimizations of Inverse Problems 显示文摘 | Ho S L YANG Shiyou BAI Yanan | 2013 | IEEE Transactions on Magnetics2013，49，5： | 1 |
| 9 | High-temperature ferromagnetic metallic phase in LaMnO_(3)/Sr_(3)Al_(2)O_(6)heterostructure显示文摘To achieve a flexible single-crystal multifunctional membrane,the freestanding process of a rigid epitaxial transition metal oxide thin film via a buffered water-dissolution sacrificial layer has attracted reasonable attentions.Owing to the difference in chemical potential,specific element affinity,and lattice constant between the target membrane and the sacrificial layer,the freestanding process may cause an indelible change of physics property once the target thin film is sensitive to the above factors.Here,the heterostructures composed of the generally adopted sacrificial layer Sr_(3)Al_(2)O_(6)(SAO)and LaMnO_(3)(LMO)have been systematically investigated.The electrical and magnetic properties of LMO show extreme sensitivity to the thickness of SAO(tSAO).Then we have also found that LMO/SAO heterostructures can exhibit the coexistence of two ferromagnetic phases,the significantly enhanced Curie temperature~342 K,and the large magnetoresistance-23.3%at 300 K,which is similar to the optimal-doped manganite such as La_(2/3)Sr_(1/3)MnO_(3).X-ray diffraction results show that continuously tunable strain from out-of-plane tension to relaxation and then to compression can be generated by adjusting tSAO.This strain can stabilize the migrated oxygen from LMO to SAO,which is induced by the large oxygen affinity difference between Bsite Mn and Al.It is believed that these unexpected electrical/magnetic phenomena are originated from the combined effects of interfacial element diffusion and strain.Our study provides a strategy for designing new magnetic phases,and a reference for the fundamental understanding of strongly correlated transition metal oxide systems in the freestanding process. | Di Wang Bin He Jinrui Guo Qixiang Wang Chaoqun Shi Yue Han Hong Fang Jie Wang Nana Zhang Peng Zhang Yanan Chen Changwen Zhang Weiming Lü Shishen Yan | 2022 | Journal of Materials Science & Technology2022，，24： | 0 |
| 10 | VEGFR2 inhibition hampers breast cancer cell proliferation via enhanced mitochondrial biogenesis显示文摘Objective:Vascular endothelial growth factor(VEGF),apart from its predominant roles in angiogenesis,can enhance cancer cell proliferation,but its mechanisms remain elusive.The purpose of the present study was therefore to identify how VEGF regulates cancer cell proliferation.Methods:VEGF effects on cancer cell proliferation were investigated with the VEGF receptor 2 inhibitor,Ki8751,and the breast cancer cell lines,MCF-7 and MDA-MB-231,using flow cytometry,mass spectrometry,immunoblotting,and confocal microscopy.Data were analyzed using one-way analysis of variance followed by Tukey’s multiple comparison test.Results:VEGF blockade by Ki8751 significantly reduced cancer cell proliferation,and enhanced breast cancer cell apoptosis.Mass spectrometric analyses revealed that Ki8751 treatment significantly upregulated the expression of mitochondrial proteins,suggesting the involvement of mitochondrial biogenesis.Confocal microscopy and flow cytometric analyses showed that Ki8751 treatment robustly increased the mitochondrial masses of both cancer cells,induced endomitosis,and arrested cancer cells in the high aneuploid phase.VEGFR2 knockdown by sh RNAs showed similar effects to those of Ki8751,confirming the specificity of Ki8751 treatment.Enhanced mitochondrial biogenesis increased mitochondrial oxidative phosphorylation and stimulated reactive oxygen species(ROS)production,which induced cancer cell apoptosis.Furthermore,Ki8751 treatment downregulated the phosphorylation of Akt and PGC1α,and translocated PGC1αinto the nucleus.The PGC1αalterations increased mitochondrial transcription factor A(TFAM)expression and subsequently increased mitochondrial biogenesis.Conclusions:VEGF enhances cancer cell proliferation by decreasing Akt-PGC1α-TFAM signaling-mediated mitochondrial biogenesis,ROS production,and cell apoptosis.These findings suggested the anticancer potential of Ki8751 via increased mitochondrial biogenesis and ROS production. | Hao Ni Min Guo Xuepei Zhang Lei Jiang Shuai Tan Juan Yuan Huanhuan L Cui Yanan Min Junhao Zhang Susanne Schlisio Chunhong Ma Wangjun Liao Monica Nister Chunlin Chen Shuijie Li Nailin Li | 2021 | Cancer Biology & Medicine2021，18，1： | 0 |
| 11 | Discovery of prenylated indole alkaloid and natural xanthone from cold-seep sediment derived fungus Talaromyces funiculosus SD-523显示文摘A new prenylated indole alkaloid 11,17-epi-mangrovamide A(1),a new natural occurring product,1,7-dihydroxy-6-methyl-8-hydroxymethyl-xanthone(2),two known alkaloids,mangrovamide A(3)and mangrovamide G(4),and four known polyketide derivatives(5–8)were isolated and identified from the cold-seep sediment derived fungal strain Talaromyces funiculosus SD-523.Their structures were elucidated by combination of nuclear magnetic resonance(NMR),high resolution electrospray ionization mass spectroscopy(HRESIMS),quantum chemical electronic circular dichroism(ECD),and DP4+probability analysis as well as by comparison of the data with literature reports.All isolated compounds were tested for antibacterial activities. | Yanan WANG Xiaoming LI Fengyi LÜ Suiqun YANG Linghong MENG Bingui WANG | 2023 | Journal of Oceanology and Limnology2023，41，3： | 0 |
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