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| 1 | Selection and development of representative simple sequence repeat primers and multiplex SSR sets for high throughput automated genotyping in maize显示文摘In the current study, 1900 maize simple sequence repeat (SSR) primers published in MaizeGDB were screened utilizing reference literature, 15 representative Chinese maize inbred lines and 15 Chinese maize hybrids from national regional testing. In total, 500 highly polymorphic primers were identified and used to construct a genetic map. 100 evenly distributed primers, 10 primers per chromosome, were further selected as a set of universal SSR core primers, recommended as preferred primers for general studies. These core primers were then redesigned and used to construct a high throughput multiplex PCR system based on a five-color fluorescence capillary detection system. We report here that two sets of ten-plex PCR combinations have been constructed, each consisting of 10 primers, with one primer per chromosome. | WANG FengGe ZHAO JiuRan DAI JingRui YI HongMei KUANG Meng SUN YanMei YU XinYan GUO JingLun WANG Lu | 2007 | Chinese Science Bulletin2007，52，2： | 35 |
| 2 | Packaging and Temperature Compensation of Fiber Bragg Grating for Strain Sensing: A Survey显示文摘 | Yi KUANG Yongxing GUO Li XIONG Wenlong LIU | 2018 | Photonic Sensors2018，8，4： | 16 |
| 3 | An enriched environment increases the expression of fibronectin type Ⅲ domain-containing protein 5 and brain-derived neurotrophic factor in the cerebral cortex of the ischemic mouse brain显示文摘Many studies have shown that fibronectin type III domain-containing protein 5(FDNC5) and brain-derived neurotrophic factor(BDNF) play vital roles in plasticity after brain injury. An enriched environment refers to an environment that provides animals with multi-sensory stimulation and movement opportunities. An enriched environment has been shown to promote the regeneration of nerve cells, synapses, and blood vessels in the animal brain after cerebral ischemia;however, the exact mechanisms have not been clarified. This study aimed to determine whether an enriched environment could improve neurobehavioral functions after the experimental inducement of cerebral ischemia and whether neurobehavioral outcomes were associated with the expression of FDNC5 and BDNF. This study established ischemic mouse models using permanent middle cerebral artery occlusion(pMCAO) on the left side. On postoperative day 1, the mice were randomly assigned to either enriched environment or standard housing condition groups. Mice in the standard housing condition group were housed and fed under standard conditions. Mice in the enriched environment group were housed in a large cage, containing various toys, and fed with a standard diet. Sham-operated mice received the same procedure, but without artery occlusion, and were housed and fed under standard conditions. On postoperative days 7 and 14, a beam-walking test was used to assess coordination, balance, and spatial learning. On postoperative days 16–20, a Morris water maze test was used to assess spatial learning and memory. On postoperative day 15, the expression levels of FDNC5 and BDNF proteins in the ipsilateral cerebral cortex were analyzed by western blot assay. The results showed that compared with the standard housing condition group, the motor balance and coordination functions(based on beam-walking test scores 7 and 14 days after operation), spatial learning abilities(based on the spatial learning scores from the Morris water maze test 16–19 days after operation), and memory abilities(based on the memory scores of the Morris water maze test 20 days after operation) of the enriched environment group improved significantly. In addition, the expression levels of FDNC5 and BDNF proteins in the ipsilateral cerebral cortex increased in the enriched environment group compared with those in the standard housing condition group. Furthermore, the Pearson correlation coefficient showed that neurobehavioral functions were positively associated with the expression levels of FDNC5 and BDNF(r = 0.587 and r = 0.840, respectively). These findings suggest that an enriched environment upregulates FDNC5 protein expression in the ipsilateral cerebral cortex after cerebral ischemia, which then activates BDNF protein expression, improving neurological function. BDNF protein expression was positively correlated with improved neurological function. The experimental protocols were approved by the Institutional Animal Care and Use Committee of Fudan University, China(approval Nos. 20160858 A232, 20160860 A234) on February 24, 2016. | Ke-Wei Yu Chuan-Jie Wang Yi Wu Yu-Yang Wang Nian-Hong Wang Shen-Yi Kuang Gang Liu Hong-Yu Xie Cong-Yu Jiang Jun-Fa Wu | 2020 | Neural Regeneration Research2020，15，9： | 12 |
| 4 | Activation of paternally expressed imprinted genes in newly derived germline-competent mouse parthenogenetic embryonic stem cell lines显示文摘单性生殖的胚胎的茎(足) 细胞为学习位于印的 genomic 下面的分子的机制提供一个珍贵试管内模型系统。然而,足房间的 thepluripotency 和父亲一般地表示的印的基因的表示侧面一直不是充分探索了。在这研究,三根老鼠足房间线被建立,在扩大文化的这些房间的区别潜力被评估。无差别的房间有正常核型和同型结合的染色体,并且表示了 ES-cell-specific 分子的标记。房间在超过 50 个段落以后仍然保持无差别并且展出了 pluripotentdifferentiation 能力。确定的 ES 房间的所有三根线生产了 teratomas;ES 房间的二根线生产了怪物和细菌线传播。而且,在这些房间的父亲一般地表示的印的基因 Snrpn, U2af1-rs1, Peg3,影响, Zfp127, Dlk1 和 Mest 的激活被检测。父亲一般地表示的印的基因被发现在单性生殖的联盟者的胚囊阶段被表示的一些激活胚胎试管内,他们的表示水平与扩大的足细胞培养增加了。而且,我们在足房间的这些父亲一般地表示的印的基因的激活在 ther 的甲基化与一个变化被联系的数据表演鼓舞了差别 methylated 区域。这些调查结果为足房间的 thepluripotency 提供直接证据并且在足房间表明在脱氧核糖核酸甲基化模式和父亲一般地表示的印的基因的激活之间的协会。因此,确定的 ES 房间线为在哺乳动物的开发学习 epigenetic 规定提供一个珍贵模型。 | Hua Jiang Bowen Sun Weicheng Wang Zhihong Zhang Furong Gao Guilai Shi Bing Cui XiangyinKong Zhao He Xiaoyan Ding Ying Kuang Jian Fei Yi Juan Sun Yun Feng Ying Jin | 2007 | Cell Research2007，17，9： | 10 |
| 5 | Isolation and characteristics of autoreactive T cells specific to aggrecan G1 domain from rheumatoid arthritis patients显示文摘Our previous work showed that the cartilage proteoglycan aggrecan could induce an erosive polyarthritis and spondylitis in BALB/c mice and the GI globular domain of the aggrecan (GI) contained the arthritogenic region. To elucidate whether autoreactive T cells to G1 are expressed in rheumatoid arthritis patients, we analyzed the frequency of human G1-specific T cells in the peripheral blood of five rheumatoid arthritis patients and tried to establish G1-reactive T cell lines from these rheumatoid arthritis patients. The results showed that the G1-specific T cells in PBL were detectable at the range of 4.97 ±0.5 ×10-6 in peripheral blood lymphocytes. We have also generated 15 G1-specific T lymphocyte lines from these pateints with a standard split-well method. All these cells expressed fine specificity to human recombinant G1, but not to unrelated antigen. All the 15 lines expressed a panT cell marker and 13 of them selectively used the αβ T cell receptor. Two of them used rye T cell receptor. The 13 of these T cell lines was CD4 positive. One line expressed CD8. One line expressed both CD4 and CD8. Moreover, 14 out of 15 lines expressed the Th-1 cytokine profile, characterized by interferon-γpositivity and IL-4 negativity. No Th-2 type cell line was generated. These data provide strong evidence in favor of the presence of autoreactive T cells in the rheumatoid arthritis pateints. What is the mechanism(s) that these autoreactive T cells attack self-target and whether these G1-specific, Th-1 type T cell lines can induce arthritis in immune deficiency mice are currently under investigation. | LI NING LI DONG QING ZHANG KUANG YAN ZHOU ANNIE CARTMAN JEAN YVES LEROUX A ROBIN POOLE YI PING ZHANG ( Shanghai Institute of Immunology, Shanghai Second Medical University, Shanghai 200025, China)(Joint Diseases Laboratory, Shriners Hospital, Dep | 2000 | Cell Research2000，10，1： | 7 |
| 6 | A simple way to make pre-stressed ceramics with high strength显示文摘A pre-stressing design and a simple fabrication technology to substantially improve the strength of ceramic components are presented.Residual surface compressive stress is generated in ceramic components by pressureless sintering of a green bulk coated with a thin layer of low coefficient of thermal expansion(CTE).The stress level can be controlled by changing the cross-section area ratio,Young's modulus ratio and CTE ratio of the coating.Pre-stressed ZrO_(2) ceramics coated with Al_(2)O_(3) can achieve a flexural strength of 1330±52MPa,45% higher than their uncoated counterpart.Similarly,the flexural strength of building porcelain tiles is increased by 70%,from 67±3 MPa to 114±5MPa.The damage tolerance of pre-stressed ZrO_(2) ceramics is excellent with a high residual strength of ~1200 MPa in a thermal shock test at 325℃.This simple technique can improve the mechanical performance of ceramic components with no limitation of size and shape. | Yiwang Bao Fenghua Kuang Yi Sun Yueming Li Detian Wan Zongyang Shen Delong Ma Lingfeng He | 2019 | Journal of Materiomics2019，5，4： | 7 |
| 7 | Numerical study of shoreline changes by emergency beach nourishment project at the Middle Beach of Beidaihe, China显示文摘Beach nourishment is a common coastal management strategy used to protect beach from erosion along the sandy coastlines. This method has been successfully applied to an emergency project at the West Beach of Beidaihe in the summer of 2008 and the full West Beach nourishment project in 2009-2010, which is the direct base of this study. Some basic information about the emergency engineering area at the Middle Beach is firstly described. The shoreline change of this area, including the analysis of beach width in five monitoring profiles in the bathing places of Middle Beach, is then discussed. After that a numerical model based on one-line theory is established and the numerical results agree well with the measured shorelines, which indicates that the model is appropriate and is qualified to predict the shoreline change of the Middle Beach. With the same model and parameters, long-term performance of the project is predicted, and the result shows that without follow-up nourishment and project, the bathing places can remain suitable for bathing for about 10 a. It is suggested to nourish the beach in time and carry out the beach nourishment project for the full Middle Beach in Beidaihe. | ZHANG Yu HE Lulu KUANG Cuiping PAN Yi GU Jie YANG Yanxiong ZHANG Jiabo | 2012 | Acta Oceanologica Sinica2012，31，1： | 4 |
| 8 | Overexpression CPT1A reduces lipid accumulation via PPARα/CD36 axis to suppress the cell proliferation in ccRCC显示文摘Clear cell renal carcinoma(ccRCC)is histologically defined by its cytoplasmic lipid deposits.Lipid metabolism disorder largely increases the risk of ccRCC.In this study,we aimed to investigate the biological functions and molecular mechanisms of carnitine palmitoyl transferase 1A(CPT1A)in ccRCC.Our results showed that CPT1A is decreased in ccRCC clinical samples and cell lines compared with that in normal samples.Lentivirus overexpressing CPT1A was used to investigate the neoplastic phenotypes of ccRCC,and the results showed that lipid accumulation and tumor growth are attenuated both in vitro and in vivo.In addition,CPT1A prevents cholesterol uptake and lipid accumulation by increasing the peroxisome proliferator-activated receptorα(PPARα)level through regulation of Class B scavenger receptor type 1(SRB1)and cluster of differentiation 36(CD36).Furthermore,PI3K/Akt signaling pathway promotes tumor cell proliferation in ccRCC,which is related to the enhanced expression of CD36.Functionally,weakened CPT1A expression is critical for lipid accumulation to promote ccRCC development.Collectively,our research unveiled a novel function of CPT1A in lipid metabolism via PPARα/CD36 axis,which provides a new theoretical explanation for the pathogenesis of ccRCC.Targeting CPT1A may be a potential therapeutic strategy to treat ccRCC. | Hui Yang Hongbo Zhao Zhongkun Ren Xiaojia Yi Qiao Zhang Zhe Yang Yingmin Kuang Yuechun Zhu | 2022 | Acta Biochimica et Biophysica Sinica2022，54，2： | 4 |
| 9 | Simultaneous determination of 35 constituents and elucidation of effective constituents in a multi-herb Chinese medicine formula Xiaoer-Feire-Kechuan显示文摘Xiaoer-Feire-Kechuan(XFK) is an 11-herb Chinese medicine formula to treat cough and pulmonary inflammation.The complicated composition rendered its chemical analysis and effective-component elucidation.In this study,we combined quantitative analysis and bioactivity test to reveal the antiinflammatory constituents of XFK.First,UPLC-DAD and UHPLC/Q-Orbitrap-MS methods were established and validated to quantify 35 analytes(covering 9 out of 11 herbs) in different XFK formulations.Parallel reaction monitoring mode built in Q-Orbitrap-MS was used to improve the sensitivity and selectivity.Then,anti-inflammatory activities of the 35 analytes were analyzed using in vitro COX-2 inhibition assay.Finally,major analytes forsythosides H,I,A(8-10),and baicalin(15)(total contents varied from 21.79 to 91.20 mg/dose in different formulations) with significant activities(inhibitory rate ≥ 80%) were proposed as the anti-inflammatory constituents of XFK.The present study provided an effective strategy to discover effective constituents of multi-herb formulas. | Zhanpeng Shang Lulu Xu Yi Kuang Yan Lin Shuang Liu Long Sun Tao Bo Min Ye Xue Qiao | 2021 | Journal of Pharmaceutical Analysis2021，11，6： | 4 |
| 10 | Low effect‐site concentration of propofol target‐controlled infusion reduces the risk of hypotension during endoscopy in a T aiwanese population显示文摘 | Wen‐Hung Hsu Sophie SW Wang Hsiang‐Yao Shih Meng‐Chieh Wu Yi‐Yu Chen Fu‐Chen Kuo Hui‐Ying Yang Shun‐Li Chiu Koung‐Shing Chu Kuang‐I Cheng Deng‐Chyang Wu I‐Cheng Lu | 2013 | Journal of Digestive Diseases2013，，3： | 3 |
| 11 | Outage probability analysis for superposition coded symmetric relaying显示文摘Superposition coded symmetric relaying is a bandwidth-efficient cooperative scheme where each source node simultaneously transmits both its own 'local' packet and 'relay' packet that originated at its partner by adding the modulated local and relay signals in Euclidean space. This paper investigates the power allocation and outage probability of a superposition coded symmetric relaying system with finite-constellation signaling. We first derive the mutual information (MI) metrics for the system. The derived MI metrics consist of two parts: one represents the MI conveyed by the modulated signal corresponding to its own data, and the other represents the MI conveyed by the modulated signal corresponding to its partner's data. Using MI based effective signal-to-noise ratio mapping technique, we attain expressions for the outage probability. Furthermore, we discuss power allocation policies that minimize the outage probability. Simulation results are presented to verify the correctness of the outage probability analysis and the benefits of the power allocation. | WU Yi ZHENG Meng FEI ZeSong LARSSON Erik G. KUANG JingMing | 2013 | Science China(Information Sciences)2013，56，2： | 3 |
| 12 | Trichosanthin inhibits T cell activation by interfering with the recruitment of ZAP-70 to CD3 ζchain显示文摘Plant protein Trichosanthin (Tk) has been shown in our previous experiments to suppress antigenic response of T cells. Here we explored its inhibitory mechanisms on the proliferation of human Jurkat leukemia T cell triggered by anti-CD3 McAb. By examination of tyrosine phosphorylation of cell lysate, we were able to show that Tk could interfere with the PTK-related activity in the TCR/CD3initiated signal transduction in addition to blocking the phosphorylation of PKC. As shown in our experiment,the expression intensity of ZAP-70, a kind of protein tyrosine kinase, was not changed but its phosphorylation could be inhibited. When physical link between CD3(chain and ZAP-70 was further examined by using coimmunoprecipitation after pluse-treatment of the cell line with Tk, the anti-CD3 McAb-induced recruitment of ZAP70 to CD3 ζ chain was observed to be blocked in some extent. This may account for, at least in part, how Trichosanthin was able to inhibit the TCR-triggered T cell proliferation. | HONG JIAN SAI LI FU ZHONG YI SHEN PEI HUA LU KUANG YEN CHOU (Shanghai Institute of Immunology, Shanghai Second Medical University, Shanghai China) | 1998 | Cell Research1998，8，1： | 3 |
| 13 | Is High Serum Uric Acid a Risk Marker or a Target for Treatment? Examination of its Independent Effect in a Large Cohort With Low Cardiovascular Risk显示文摘 | Chi Pang Wen Ting-Yuan David Cheng Hui Ting Chan Min Kuang Tsai Wen-Shen Isabella Chung Shan Pou Tsai Mark L. Wahlqvist Yi Chen Yang Shiuan Be Wu Po Huang Chiang Sung Feng Wen | 2010 | American Journal of Kidney Diseases2010，，2： | 2 |
| 14 | Prospective, naturalistic study of open-label OROS methylphenidate treatment in Chinese school-aged children with attention-deficit/hyperactivity disorder显示文摘背景注意赤字活动过度混乱( ADHD )在童年期间是最普通的心理混乱之一,由活动过度, impulsivity 和疏忽的核心症状描绘了并且自己把大负担放在孩子上,他们的家庭和 society.Osmotic 释放口头的系统 methylphenidate (OROS哩/时)开发克服一些限制的一次每日的控制版本明确的表达与立即版本的 methylphenidate (红外哩/时)被联系 .It | ZHENG Yi WANG Yu-feng QIN Jiong WANG Li-wen ZOU Li-ping J IN Xing-ming XU Tong WANG Yi OI Yuan-li GONG Mei-en YIN Qing-yun MAI Jian-ning JING Jin LUO Xiang-yang MA Hong-wei LI Hai-bo XIE Ling LIYan Kuang Gui-fang YI Ming-ji WANG Feng ZHU Xiao-hua YAO Yan-bin | 2011 | Chinese Medical Journal2011，，20： | 2 |
| 15 | Comparison of light absorption and oxidative potential of biodiesel/diesel and chemicals/diesel blends soot particles显示文摘Soot particles,mainly coming from fuel combustion,affect climate forcing through absorbing light and also result in adverse human health outcomes.Though biodiesel or additives blending with diesel was considered environmentally friendly,the understanding on absorbing and oxidative capacity of soot emitted from them are still unclear.The watersoluble organic carbon(WSOC)content,surface chemical structure,light absorption and oxidative potential(OPDTT)of soot from biodiesel/diesel and chemicals/diesel blends were investigated utilizing total organic carbon analyzer,X-ray photoelectron spectrometer,ultraviolet–visible spectrophotometry and dithiothreitol(DTT)assay.The differences and correlations between soot properties were statistically analyzed.Chemicals/diesel blends soot owned significantly higher WSOC content,ratio of mass absorbing efficiency(MAE)in250 and 365 nm(E2/E3),OPDTT,and higher surface carbonyl content.Coconut biodiesel/diesel blends soot contained evidently higher aromatic carbon–oxygen single bond(ArC–O)content,and higher MAE365.The individual comparison of biodiesel/diesel blends showed20%coconut biodiesel blend owned the lowest WSOC,E2/E3 and OPDTT,while highest ArC–O and MAE365,representing strongest absorbing properties.Association analysis showed OPDTTwas significantly positively correlated with WSOC.Further,the evident negative correlation between MAE365 and OPDTT was observed.Our results showed coconut biodiesel/diesel blends soot induced lower levels of oxidative potential,whereas absorption of light was higher,which have far reaching consequences on climate forcing.Therefore,it is important to evaluate the balance point between light-absorbing properties and oxidative potential,under the wide use of biodiesel. | Yu Kuang Yi Guo Jiaqi Chai Jing Shang Jiali Zhu Svetlana Stevanovic Zoran Ristovski | 2020 | Journal of Environmental Sciences2020，32，1： | 2 |
| 16 | Optimized protocol of multiple post-processing techniques improves diagnostic accuracy of multidetector computed tomography in assessment of small bowel obstruction compared with conventional axial and coronal reformations显示文摘BACKGROUND Axial and coronal reformations have been a widely used image post-processing protocol for the ordinary multidetector computed tomography(MDCT)examination of patients with small bowel obstruction(SBO) or other abdominal diseases. The diagnostic accuracy of MDCT for assessing SBO is expected to be further improved through the use of multiple post-processing techniques.AIM To systemically evaluate the diagnostic accuracy and efficiency of an optimized protocol using multiple post-processing techniques for MDCT assessment of SBO and secondary bowel ischemia.METHODS This retrospective cross-sectional study included 106 patients with clinically suspected SBO. Two readers applied three protocols to image post-processing and interpretation of patients' MDCT volume data. We compared the three protocols based on time spent, number of images, diagnostic self-confidence,agreement, detection rate, and accuracy of detection of SBO and secondary bowel ischemia.RESULTS Protocol 2 resulted in more time spent and number of images than protocols 1 and 3(P < 0.01), but the results of the two readers using the same protocol were not different(P > 0.05). Using protocol 3, both readers added multiple postprocessing techniques at frequencies of 29.2% and 34.9%, respectively, for obstruction cause, and 32.1% and 30.2%, respectively, for secondary bowel ischemia. Protocols 2 and 3 had higher total detection rates of obstruction cause and secondary bowel ischemia than protocol 1(P < 0.01), but no difference was detected between protocols 2 and 3(P > 0.05). The accuracy, sensitivity,specificity, positive predictive value and negative predictive value of protocols 2 and 3 were superior to those of protocol 1 for evaluating obstruction cause and secondary bowel ischemia.CONCLUSION Our optimized protocol of multiple post-processing techniques can both guarantee efficiency and improve diagnostic accuracy of MDCT for assessing SBO and secondary bowel ischemia. | Lian-Qin Kuang Wei Tang Ran Li Cheng Cheng Shuang-Yue Tang Yi Wang | 2019 | World Journal of Gastroenterology2019，25，9： | 2 |
| 17 | Model-free Demand Response Scheduling Strategy for Virtual Power Plants Considering Risk Attitude of Consumers显示文摘Driven by modern advanced information and communication technologies,distributed energy resources have great potential for energy supply within the framework of the virtual power plant(VPP).Meanwhile,demand response(DR)is becoming increasingly important for enhancing the VPP operation and mitigating the risks associated with the fluctuation of renewable energy resources(RESs).In this paper,we propose an incentivebased DR program for the VPP to minimize the deviation penalty from participating in the power market.The Markov decision process(MDP)with unknown transition probability is constructed from the VPP’s prospective to formulate an incentivebased DR program,in which the randomness of consumer behavior and RES generation are taken into consideration.Furthermore,a value function of prospect theory(PT)is developed to characterize consumer’s risk attitude and describe the psychological factors.A model-free deep reinforcement learning(DRL)-based approach is proposed to deal with the randomness existing in the model and adaptively determine the optimal DR pricing strategy for the VPP,without requiring any system model information.Finally,the results of cases tested demonstrate the effectiveness of the proposed approach. | Yi Kuang Xiuli Wang Hongyang Zhao Tao Qian Nailiang Li Jianxue Wang Xifan Wang | 2023 | CSEE Journal of Power and Energy Systems2023，9，2： | 2 |
| 18 | Recent diagnostic developments at the 100 kJ-level laser facility in China显示文摘A 100 kJ-level laser facility has been designed to study inertial confinement fusion physics in China.This facility incorporates various diagnostic techniques,including optical,x-ray imaging,x-ray spectrum,and fusion product diagnostics,as well as general diagnostics assistance systems and central control and data acquisition systems.This paper describes recent developments in diagnostics at the facility. | Feng Wang Shaoen Jiang Yongkun Ding Shenye Liu Jiamin Yang Sanwei Li Tianxuan Huang Zhurong Cao Zhenghua Yang Xin Hu Wenyong Miao Jiyan Zhang Zhebin Wang Guohong Yang Rongqing Yi Qi Tang Longyu Kuang Zhichao Li Dong Yang Yulong Li Xiaoshi Peng Kuan Ren Baohan Zhang | 2020 | Matter and Radiation at Extremes2020，5，3： | 2 |
| 19 | Hybrid Energy Sharing Mechanism for Integrated Energy Systems Based on the Stackelberg Game显示文摘Integrating the sharing economy and the power industry is of positive significance for the development of the energy market.With the energy market transforming from a traditional vertical structure to an interactive and competitive structure,users'roles need to change,along with supply and demand interacting more frequently.Thus,the traditional centralized optimization method for a single energy source can hardly reveal the complex multi-entity behavior of multi-energy coupling.Therefore,this paper establishes a distributed electrical-gas-thermal energy sharing mechanism centered on an energy hub that can converse energy,and build a more applicable integrated energy system body.First,the supply-demand interaction and the energy conversion process is constructed with reference to the operationa丨mode of’a sharing economy and the dual role of prosumers.A Stackelberg model is established with the integrated energy system operator as the leader and prosumers as the followers,to simultaneously optimize the profit of the leader in the upper level and the comfort of the fo!lowers,energy use and utility in the lower level.Furthermore,for protecting the participants’privacy,a distributed algorithm is used to find the optimal solution to equilibrate the model,and the existence and uniqueness of the solution is proved.Finally,a case study validates the effectiveness of the hybrid energy sharing mechanism and provides a reference for the integration of the energy sharing economy with the integrated energy system. | Qiao Peng Xiuli Wang Yi Kuang Yifei Wang Hongyang Zhao Zhicheng Wang Jianhu Lyu | 2021 | CSEE Journal of Power and Energy Systems2021，7，5： | 2 |
| 20 | Face and object visual working memory deficits in first-episode schizophrenia correlate with multiple neurocognitive performances显示文摘Background Working memory(WM)deficit is considered a core feature and cognitive biomarker in patients with schizophrenia.Several studies have reported prominent object WM deficits in patients with schizophrenia,suggesting that visual WM in these patients extends to non-spatial domains.However,whether non-spatial WM is similarly affected remains unclear.Aim This study primarily aimed to identify the processing of visual object WM in patients with first-episode schizophrenia.Methods The study included 36 patients with first-episode schizophrenia and 35 healthy controls.Visual object WM capacity,including face and house WM capacity,was assessed by means of delayed matching-to sample visual WM tasks,in which participants must distribute memory so that they can discriminate a target sample.We specifically examined their anhedonia experience by the Temporal Experience of Pleasure Scale and the Snaith-Hamilton Pleasure Scale.Cognitive performance was measured by the Repeatable Battery for the Assessment of Neuropsychological Status(RBANS).Results Both face and house WM capacity was significantly impaired in patients with schizophrenia.For both tasks,the performance of all the subjects was worse under the high-load condition than under the low-load condition.We found that WM capacity was highly positively correlated with the performance on RBANS total scores(r=−0.528,p=0.005),RBANS delayed memory scores(r=−0.470,p=0.013),RBANS attention scores(r=−0.584,p=0.001),RBANS language scores(r=−0.448,p=0.019),Trail-Making Test:Part A raw scores(r=0.465,p=0.015)and simple IQ total scores(r=−0.538,p=0.005),and correlated with scores of the vocabulary test(r=−0.490,p=0.011)and scores of the Block Diagram Test(r=−0.426,p=0.027)in schizophrenia.No significant correlations were observed between WM capacity and Positive and Negative Syndrome Scale symptoms.Conclusions Our research found that visual object WM capacity is dramatically impaired in patients with schizophrenia and is strongly correlated with other measures of cognition,suggesting a mechanism that is critical in explaining a portion of the broad cognitive deficits observed in schizophrenia. | Yi Liu Taiyong Bi Bei Zhang Qijie Kuang Haijing Li Kunlun Zong Jingping Zhao Yuping Ning Shenglin She Yingjun Zheng | 2021 | General Psychiatry2021，34，1： | 2 |
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