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| 1 | Southwest monsoon changes indicated by oxygen isotope of ostracode shells from sediments in Qinghai Lake since the late Glacial显示文摘The δ 18O records of ostracode shells in sediments of core QH-2000 from Qinghai Lake can be used as a better proxy to reflect monsoon changes. Low monsoon precipitation between 17.5 and 11 cal. ka BP is indicated by positive δ 18O values averaging 2.37‰. A fast shift in δ 18O from positive at 11 cal. ka BP to negative at 10 cal. ka BP indicates sharp increase of monsoon precipitation. An interval of generally high monsoon precipitation is observed between 10 and 6 cal. ka BP with δ 18O values averaging -2.15‰. Decrease of monsoon precipitation between 6 and 2.5 cal. ka BP is indicated by positive δ 18O values. δ 18O keeps positive values averaging 3.0‰ between 2.5 and 0 cal. ka BP suggesting low high monsoon precipitation. The climatic changes indicated by δ 18O records of ostracode shells in sedi- ments of core QH-2000 from Qinghai Lake and our broader regional comparison show that the climate in Qinghai Lake since the late Glacial is probably controlled by southwest monsoon other than southeast monsoon. | LIU XingQi SHEN Ji WANG SuMin WANG YongBo LIU WeiGuo | 2007 | Chinese Science Bulletin2007，52，4： | 39 |
| 2 | Chemical weathering intensity and element migration features of the Xiashu loess profile in Zhenjiang, Jiangsu Province显示文摘在 Zhenjiang 的 Xiashu 黄土侧面的化学捱过紧张和元素迁居特征在这篇论文被学习。(1 ) Xiashu 黄土侧面经历了中等化学捱过。看起来降水是更重要的 | CHEN Yingyong LI Xusheng HAN Zhiyong YANG Shouye WANG Yongbo YANG Dayuan | 2008 | Journal of Geographical Sciences2008，18，3： | 25 |
| 3 | The China Alzheimer Report 2022显示文摘China’s population has rapidly aged over the recent decades of social and economic development as neurodegenerative disorders have proliferated,especially Alzheimer’s disease(AD)and related dementias(ADRD).AD’s incidence rate,morbidity,and mortality have steadily increased to make it presently the fifth leading cause of death among urban and rural residents in China and magnify the resulting financial burdens on individuals,families and society.The‘Healthy China Action’plan of 2019-2030 promotes the transition from disease treatment to health maintenance for this expanding population with ADRD.This report describes related epidemiological trends,evaluates the economic burden of the disease,outlines current clinical diagnosis and treatment status and delineates existing available public health resources.More specifically,it examines the public health impact of ADRD,including prevalence,mortality,costs,usage of care,and the overall effect on caregivers and society.In addition,this special report presents technical guidance and supports for the prevention and treatment of AD,provides expertise to guide relevant governmental healthcare policy development and suggests an information platform for international exchange and cooperation. | Rujing Ren Jinlei Qi Shaohui Lin Xinya Liu Peng Yin Zhihui Wang Ran Tang Jintao Wang Qiang Huang Jianping Li Xinyi Xie Yongbo Hu Shishuang Cui Yuan Zhu Xiaoping Yu Pengfei Wang Yikang Zhu Yiran Wang Yanyan Huang Yisong Hu Ying Wang Chunbo Li Maigeng Zhou Gang Wang | 2022 | General Psychiatry2022，35，1： | 20 |
| 4 | A chlorinated copolymer donor demonstrates a 18.13% power conversion efficiency显示文摘The rapid development of low-bandgap(LBG)nonfullerene acceptors and wide-bandgap(WBG)copolymer donors in recent years has boosted the power conversion efficiency(PCE)of organic solar cells(OSCs)to the 18%level[1−21].The commercialization of OSCs is highly expected.However,critical issues like the cost and the stability also determine whether OSCs can enter the market or not[22]. | Jianqiang Qin Lixiu Zhang Chuantian Zuo Zuo Xiao Yongbo Yuan Shangfeng Yang Feng Hao Ming Cheng Kuan Sun Qinye Bao Zhengyang Bin Zhiwen Jin and Liming Ding | 2021 | Journal of Semiconductors2021，42，1： | 19 |
| 5 | A carbon-oxygen-bridged ladder-type building block for efficient donor and acceptor materials used in organic solar cells显示文摘A carbon-oxygen-bridged ladder-type donor unit(CO5) was invented and prepared via an ‘‘intramolecular demethanolization cyclization' approach. Its single crystal structure indicates enhanced planarity compared with the carbon-bridged analogue indacenodithiophene(IDT). Owing to the stronger electron-donating capability of CO5 than IDT, CO5-based donor and acceptor materials show narrower bandgaps. A donor-acceptor(D-A) copolymer donor(PCO5TPD) and an A-D-A nonfullerene acceptor(CO5IC) demonstrated higher performance than IDT-based counterparts, PIDTTPD and IDTIC, respectively. The better performance of CO5-based materials results from their stronger light-harvesting capability and higher charge-carrier mobilities. | Zuo Xiao Fan Liu Xinjian Geng Jianqi Zhang Shizhe Wang Yujun Xie Zhen Li Huai Yang Yongbo Yuan Liming Ding | 2017 | Science Bulletin2017，62，19： | 16 |
| 6 | Progress of the key materials for organic solar cells显示文摘Organic solar cells have attracted academic and industrial interests due to the advantages like lightweight,flexibility and roll-to-roll fabrication.Nowadays,18%power conversion efficiency has been achieved in the state-of-the-art organic solar cells.The recent rapid progress in organic solar cells relies on the continuously emerging new materials and device fabrication technologies,and the deep understanding on film morphology,molecular packing and device physics.Donor and acceptor materials are the key materials for organic solar cells since they determine the device performance.The past 25 years have witnessed an odyssey in developing high-performance donors and acceptors.In this review,we focus on those star materials and milestone work,and introduce the molecular structure evolution of key materials.These key materials include homopolymer donors,D-A copolymer donors,A-D-A small molecular donors,fullerene acceptors and nonfullerene acceptors.At last,we outlook the challenges and very important directions in key materials development. | Yang Tong Zuo Xiao Xiaoyan Du Chuantian Zuo Yuelong Li Menglan Lv Yongbo Yuan Chenyi Yi Feng Hao Yong Hua Ting Lei Qianqian Lin Kuan Sun Dewei Zhao Chunhui Duan Xiangfeng Shao Wei Li Hin-Lap Yip Zhengguo Xiaol Bin Zhang Qingzhen Bian Yuanhang Cheng Shengjian Liu Ming Cheng Zhiwen Jin Shangfeng Yang Liming Ding | 2020 | Science China Chemistry2020，63，6： | 15 |
| 7 | Deformation, Phase Transformation and Recrystallization in the Shear Bands Induced by High-Strain Rate Loading in Titanium and Its Alloys显示文摘有双阶段的结构(alpha+beta ) 的 alpha 钛和它的合金在大约 10 ~ 的紧张率下面动态地被使变形 4 s^(-1) 。形成和微结构进化局部性砍乐队们被扫描电子显微镜学(SEM ) 和传播电子显微镜学(TEM ) 描绘。结果表明紧张和紧张率应该同时被看作机械条件为砍乐队形成,和 twinning 是变丑的一个重要模式。试验性并且在乐队以内的材料经历了的计算表演超高频率的紧张率(9X10 ~ 5 s^(-1)) 变丑,它是平均紧张率的二大小要求了为砍乐队形成;在乐队的脱臼能被压缩并且发展成房间结构;到在乐队以内的 alpha_2 的阶段转变 fromalpha 被观察,并且转变产品(alpha_2 ) 与他们的父母一起有某个结晶的取向关系;有在在乐队以内观察的直径的 10 亩 m 的一种平均尺寸的 equiaxed 谷物被建议是再结晶的结果。 | Yongbo XU Yilong BAI M.A.Meyers | 2006 | Journal of Materials Science & Technology2006，22，6： | 14 |
| 8 | Response of global lightning activity to air temperature variation显示文摘It is an issue of great attention but yet not very clear whether lightning activities increase or decrease on a warmer world. Reeve et al. presented that lightning activities in global land and the Northern Hemisphere land have posi- tive response to the increase of wet bulb temperature at 1000hPa. Is this positive response restricted only to wet bulb temperature or in land? What is the response of global light- ning activities (in both land and ocean) to the global surface air temperature variation like? This paper, based on the 5-year or 8-year OTD/LIS satellite-based lightning detecting data and the NCEP reanalysis data, makes a reanalysis of the response of the global and regional lightning activities to temperature variations. The results show that on the inter- annual time scale the global total flash rate has positive re- sponse to the variation in global surface air temperature, with the sensitivity of 17±7% K?1. Also, the seasonal mean flash rate of continents all over the world and that of conti- nents in the Northern Hemisphere have sensitive positive response to increase of global surface air temperature and wet bulb temperature, with the sensitivity of about 13±5% K?1, a bit lower than estimation of 40% K?1 in Reeve et al. However, the Southern Hemisphere and other areas like the tropics show no significant correlation. | MA Ming TAO Shanchang ZHU Baoyou LUE Weitao TAN Yongbo | 2005 | Chinese Science Bulletin2005，50，22： | 13 |
| 9 | Induced J-aggregation in acceptor alloy enhances photocurrent显示文摘Carbon-oxygen-bridged (CO-bridged) ladder-type units already proved to be promising electron-donating building blocks for making acceptor-donor-acceptor (A-D-A) nonfullerene acceptors [1].Compared with traditional carbon-bridged (C-bridged) units, CObridged units present stronger electron-donating capability due to electron-rich oxygen atoms. | Ling Liu Qishi Liu Zuo Xiao Shangfeng Yang Yongbo Yuan Liming Ding | 2019 | Science Bulletin2019，64，15： | 13 |
| 10 | Effect of long-period stacking ordered phase on microstructure,mechanical property and corrosion resistance of Mg alloys: A review显示文摘Magnesium alloys containing long period stacking ordered(LPSO) phase have been received a great deal of attention in the last decade owing to their excellent comprehensive properties of mechanical strength and corrosion resistance. In this paper, some fundamental aspects of LPSO containing Mg alloys have been reviewed, including:(1) microstructural characterization, formation conditions and the associated phase transformation of LPSO phases in Mg alloys;(2) deformation mechanism of LPSO phases and their in fl uence on the deformation mechanism of the Mg matrix;(3) effect of LPSO structure on the mechanical performance such as tensile strength, creep resistance, fracture toughness and fatigue strength;(4) corrosion behavior of LPSO containing Mg alloys and their possible applications as the biomaterials.Moreover, some remaining unsolved issues of the LPSO containing Mg alloys and the future target about how to further improve their service properties have been also described. | Daokui Xu En-hou Han Yongbo Xu | 2016 | Progress in Natural Science:Materials International2016，26，2： | 11 |
| 11 | Orexin Receptor Antagonists as Emerging Treatments for Psychiatric Disorders显示文摘Orexins comprise two neuropeptides produced by orexin neurons in the lateral hypothalamus and are released by extensive projections of these neurons throughout the central nervous system. Orexins bind and activate their associated G protein-coupled orexin type 1 receptors(OX1Rs) and OX2Rs and act on numerous physiological processes, such as sleep-wake regulation, feeding, reward,emotion, and motivation. Research on the development of orexin receptor antagonists has dramatically increased with the approval of suvorexant for the treatment of primary insomnia. In the present review, we discuss recent findings on the involvement of the orexin system in the pathophysiology of psychiatric disorders, including sleep disorders,depression, anxiety, and drug addiction. We discuss the actions of orexin receptor antagonists, including selective OX1R antagonists (SORA1s), selective OX2R antagonists(SORA2s), and dual OX1/2R antagonists (DORAs), in the treatment of these disorders based on both preclinical and clinical evidence. SORA2s and DORAs have more pronounced efficacy in the treatment of sleep disorders,whereas SORA1s may be promising for the treatment of anxiety and drug addiction. We also discuss potential challenges and opportunities for the application of orexin receptor antagonists to clinical interventions. | Ying Han Kai Yuan Yongbo Zheng Lin Lu | 2020 | Neuroscience Bulletin2020，36，4： | 10 |
| 12 | A two-terminal all-inorganic perovskite/organic tandem solar cell显示文摘Organic-inorganic lead halide perovskite solar cells(PSCs)have been marching rapidly in recent years with power conversion efficiency(PCE)boosting from 3.8%to 24.2%(NREL Best Research-Cell Efficiency Chart,http://gffzz8798726073dc471csp9ubv0xqqp0o60uk.ffgz.tsg.suse.edu.cn/pv/cell-effi ciency.html,Accessed April 2019).However,these solar cells are not stable at high temperatures due to volatile organic cations[1].Allinorganic perovskites with cesium cation like CsPbI1-xBrx present high thermal stabilities[2].By partially replacing I-with Br-,the bandgap for CsPbI1-xBrx can be tuned from 1.73 to 2.36 eV. | Qiang Zeng Ling Liu Zuo Xiao Fangyang Liu Yong Hua Yongbo Yuan Liming Ding | 2019 | Science Bulletin2019，64，13： | 10 |
| 13 | Effects of ammonia exposure on carcass traits and fatty acid composition of broiler meat显示文摘We aimed to study the effects of ammonia on carcass traits, organ indices and fatty acid composition of broilers. Four hundred 21-d-old male Arbor Acres broilers with initial weight 563.52 ± 2.82 g were randomly allotted to 1 of 4 groups treated with ammonia at <3 mg/kg(control),25 ± 3. 50 ± 3, and75 ± 3 mg/kg concentrations. Each group consisted of 4 replicates of 25 birds. Broilers from 21 to 42 d were reared on the net floor in the respiration-metabolism chambers where similar environmental conditions were maintained. At 32 and 42 d of age, carcass traits and organ indices were determined for4 birds per pen. At 42 d of age, fatty acid composition in the breast and thigh muscle of broilers was measured. Results showed as follows: 1) At 32 d, the dressing percentage of broilers exposed to 25 and75 mg/kg ammonia were lower than those in the control group(P < 0.05); eviscerated yield percentage of broilers in the 25 mg/kg ammonia group was also lower(P < 0.05). At 42 d, the dressing percentage of broilers in the ammonia treatments and the thigh muscle percentage of broilers in the 50 and 75 mg/kg ammonia groups were lower(P < 0.05) than those in the control. Breast muscle percentage of broilers exposed to 25 and 50 mg/kg ammonia and eviscerated yield percentage exposed to 50 mg/kg ammonia were lower than those in the control(P < 0.05). 2) The kidney index of broilers(d 32) exposed to ammonia was greater(P < 0.05) than that of the control. At 42 d, hepatic index of broilers exposed to ammonia was increased(P < 0.05), and spleen index was decreased(P < 0.05). 3) At 42 d, stearic(C18:0)and saturated fatty acids(SFA) in the thigh muscle of broilers were higher, while the unsaturated fatty acid:saturated fatty acid(U:F) ratio and unsaturated fatty acid(UFA) were lower in the 50 mg/kg ammonia treatment than in the control group(P < 0.05). In conclusion, ammonia over 25 mg/kg could decline carcass traits and immune organ indices and increase the kidney and hepatic indices. Further,exposure to 50 mg/kg ammonia could also decrease breast and thigh muscle yield percentage while increasing SFA content and decreasing UFA content in the thigh muscle of broilers. | Huan Xing Sujun Luan Yongbo Sun Renna Sa Hongfu Zhang | 2016 | Animal Nutrition2016，，4： | 8 |
| 14 | Molecular dynamics simulations of thermal effects in nanometric cutting process显示文摘Understanding the basic action of how material removing in nanoscale is a critical issue of producing well-formed components.In order to clarify thermal effects on material removal at atomic level,molecular dynamics(MD)simulations of nanometric cutting of mono-crystalline copper are performed with Morse,EAM and Tersoff potential.The effects of cutting speed on temperature distribution are investigated.The simulation results demonstrate that the temperature distribution shows a roughly concentric shape around shear zone and a steep temperature gradient lies in diamond tool,a relative high temperature is located in shear zone and machined surface,but the highest temperature is found in chip.At a high cutting speed mode,the atoms in shear zone with high temperature implies a large stress is built up in a local region. | GUO YongBo,LIANG YingChun,CHEN MingJun,BAI QingShun&LU LiHua Precision Research Engineering Institute,Harbin Institute of Technology,Harbin 150001,China | 2010 | Science China(Technological Sciences)2010，53，3： | 7 |
| 15 | Rice Straw-Derived Biochar Properties and Functions as Cu(Ⅱ) and Cyromazine Sorbents as Influenced by Pyrolysis Temperature显示文摘In this study, biochars from rice straw(Oryza sativa L.) were prepared at 200–600?C by oxygen-limited pyrolysis to investigate the changes in properties of rice straw biochars produced at different temperatures, and to examine the adsorption capacities of the biochars for a heavy metal, copper(Ⅱ)(Cu(Ⅱ)), and an organic insecticide of cyromazine, as well as to further reveal the adsorption mechanisms.The results obtained with batch experiments showed that the amount of Cu(Ⅱ) adsorbed varied with the pyrolysis temperatures of rice straw biochar. The biochar produced at 400?C had the largest adsorption capacity for Cu(Ⅱ)(0.37 mol kg-1) among the biochars,with the non-electrostatic adsorption as the main adsorption mechanism. The highest adsorption capacity for cyromazine(156.42 g kg-1) was found in the rice straw biochar produced at 600?C, and cyromazine adsorption was exclusively predominated by surface adsorption. An obvious competitive adsorption was found between 5 mmol L-1Cu(II) and 2 g L-1cyromazine when they were in the binary solute system. Biochar may be used to remediate heavy metal- and organic insecticide-contaminated water, while the pyrolysis temperature of feedstocks for producing biochar should be considered for the restoration of multi-contamination. | JIANG Jun Yongbo PENG YUAN Min HONG Zhineng WANG Dejian XU Renkou | 2015 | Pedosphere2015，25，5： | 7 |
| 16 | Sustainable development of coal cities in Heilongjiang province based on AHP method显示文摘The sustainable development of coal mining cities in Heilongjiang province has important effect on the economic stability and development of Heilongjiang, Northeast China, and China at large. To further the sustainable development evaluation system of coal mining cities in Heilongjiang province, based on the analytic hierarchy process (AHP) method combined with operational and scientific principles using Saaty's 1-9 scale method to construct the judgment matrix from five aspects, such as economic development and environmental quality, this paper establishes the comprehensive evaluation index system of sustainable development of coal mining cities in Heilongjiang province, including comprehensive index of industrial economic benefits and the contribution rate of science and technology. In addition, using fuzzy comprehensive evaluation method, a comprehensive evaluation is made on the indices of the four major coal mining cities of Heilongjiang. The result shows that the coal mining cities are not better than Datong of Shanxi province in many indices. The economic development and environment quality are the most important indices of the targeted layer influencing the sustainable development of coal mining cities of Heilongjiang, and their index weights are 0.4358 and 0.2844, respectively. These two indices including comprehensive index of industrial economic benefit and the ratio of environmental protection investment to GDP are the key elements influencing the two aspects. | Zhang Yupu Sun Yongbo Qin Jiangbo | 2012 | International Journal of Mining Science and Technology2012，22，1： | 7 |
| 17 | Rho kinase:A new target for treatment of cerebral ischemia/reperfusion injury显示文摘Rho kinase inhibitor fasudil hydrochloride has been shown to reduce cerebral vasospasm, to inhibit inflammation and apoptosis and to promote the recovery of neurological function. However, the effect of fasudil hydrochloride on claudin-5 protein expression has not been reported after cerebral ischemia/reperfusion. Therefore, this study sought to explore the effects of fasudil hydrochloride on blood-brain barrier permeability, growth-associated protein-43 and claudin-5 protein expression, and to further understand the neuroprotective effect of fasudil hydrochloride. A focal cerebral ischemia/reperfusion model was established using the intraluminal suture technique. Fasudil hydrochloride (15 mg/kg) was intraperitoneally injected once a day. Neurological deficit was evaluated using Longa's method. Changes in permeability of blood-brain barrier were measured using Evans blue. Changes in RhoA, growth-associated protein-43 and claudin-5 protein expression were detected using immunohistochemistry and western blotting. Results revealed that fasudil hydrochloride noticeably contributed to the recovery of neurological function, improved the function of blood-brain barrier, inhibited RhoA protein expression, and upregulated growth-associated protein-43 and claudin-5 protein expression following cerebral ischemia/reperfusion. Results indicated that Rho kinase exhibits a certain effect on neurovascular damage following cerebral ischemia/reperfusion. Intervention targeted Rho kinase might be a new therapeutic target in the treatment of cerebral ischemia/reperfusion. | Qinghong Cui Yongbo Zhang Hui Chen Jimei Li | 2013 | Neural Regeneration Research2013，8，13： | 7 |
| 18 | Blunted nitric oxide regulation in Tibetans under high-altitude hypoxia显示文摘Nitric oxide(NO) is an important molecule for vasomotor tone, and elevated NO signaling was previously hypothesized as a unique and adaptive physiological change in highland Tibetans. However, there has been lack of NO data from Tibetans living at low altitude and lowlander immigrants living at high altitude, which is crucial to test this hypothesis. Here, through cross-altitude(1990–5018 m) and cross-population(Tibetans and Han Chinese) analyses of serum NO metabolites(NOx) of 2086 individuals, we demonstrate that although Tibetans have a higher serum NOx level compared to lowlanders, Han Chinese immigrants living at high altitude show an even higher level than Tibetans. Consequently, our data contradict the previous proposal of increased NO signaling as the unique adaptive strategy in Tibetans.Instead, Tibetans have a relatively lower circulating NOx level at high altitude. This observation is further supported by data from the hypoxic experiments using human umbilical vein endothelial cells and gene knockout mice. No difference is detected between Tibetans and Han Chinese for endothelial nitric oxide synthase(e NOS), the key enzyme for circulating NO synthesis, suggesting that e NOS itself is unlikely to be the cause. We show that other NO synthesis-related genes(e.g. GCH1) carry Tibetan-enriched mutations significantly associated with the level of circulating NOx in Tibetans. Furthermore, gene network analysis revealed that the downregulation and upregulation of NOx is possibly achieved through distinct pathways.Collectively, our findings provide novel insights into the physiological and genetic mechanisms of the evolutionary adaptation of Tibetans to high-altitude hypoxia. | Yaoxi He Xuebin Qi Ouzhuluobu Shiming Liu Jun Li Hui Zhang Baimakangzhuo Caijuan Bai Wangshan Zheng Yongbo Guo Duojizhuoma Baimayangji Dejiquzong Bianba Gonggalanzi Yongyue Pan Qula Kangmin Cirenyangji Wei Guo Yangla Yi Peng Xiaoming Zhang Kun Xiang Zhaohui Yang Liangbang Wang Gengdeng Yanfeng Zhang Tianyi Wu Bing Su Chaoying Cui | 2018 | National Science Review2018，5，4： | 7 |
| 19 | Building biological foundries for next-generation synthetic biology显示文摘Synthetic biology is an interdisciplinary field that takes top-down approaches to understand and engineer biological systems through design-build-test cycles. A number of advances in this relatively young field have greatly accelerated such engineering cycles. Specifically, various innovative tools were developed for in silico biosystems design, DNA de novo synthesis and assembly, construct verification, as well as metabolite analysis, which have laid a solid foundation for building biological foundries for rapid prototyping of improved or novel biosystems. This review summarizes the state-of-the-art technologies for synthetic biology and discusses the challenges to establish such biological foundries. | CHAO Ran YUAN YongBo ZHAO HuiMin | 2015 | Science China(Life Sciences)2015，58，7： | 7 |
| 20 | A Model of Dynamic Recrystallization in Alloys during High Strain Plastic Deformation显示文摘Recrystallized grains, less than 200 nm in diameter were observed in heavily shear zones of a high strength low alloy steel and a Ni-based alloy, and Also grain refinement, less than 3 μm in diameter was made in high purity aluminum by ECAE at ambient temperature. The experimental results showed that high strain rate and large deformation could induce dynamic recrystallization.Based on dislocation dynamics and grain orientation change enhanced by plastic deformation,a model for the recrystallization process is developed. The model is used to explain the ultra fine grains which are formed at a temperature still much lower than that for the conventional | Qiang LI and Yongbo XU(State Key Laboratory for Fatigue and Fracture of Materials, Institute of Metal Research, Chinese Academy of Sciences,Shenyang 110015, China) To whom correspondence should be addressed Present address: Analysis Cener, School of Mater | 1999 | Journal of Materials Science & Technology1999，15，5： | 7 |
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