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| 1 | Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis显示文摘在蛋白质周转(蛋白质 degradome ) 的全球变化组成对内在或外来的刺激的细胞的回答的中央部分。然而,介绍蛋白质 degradome 仍然保持技术上挑战性。最近, proteasome 的抑制,例如由使用 bortezomib (BTZ ) ,为对待多重骨髓瘤和其它人恶意,但是药行动和肿瘤药抵抗还有待于被完成的为 BTZ 的机制的系统的理解作为主要化学疗法的策略出现了。这里,我们开发了并且适用 dual-fluorescence-based 蛋白质周转试金(ProTA ) 到份量上在导致 BTZ 的 proteasomal 抑制之上在人的蛋白质 degradome 介绍全球变化。ProTA 和随后的网络分析描出在 BTZ 化疗的 BTZ 行动和肿瘤药抵抗的潜在的分子的基础。最后,把 BTZ 的使用与指向识别 ProTA 的关键基因的药相结合或在 BTZ 行动的小径在多重骨髓瘤房间减少了 BTZ 抵抗。显著地, BTZ 稳定 proteasome 子单元 PSMC1 和 proteasome 集会因素 PSMD10,建议为调整 proteasome 动态平衡的以前下面欣赏的机制。因此, ProTA 是为介绍人的蛋白质 degradome 阐明的一个新奇工具药行动和抵抗的潜在的机制,它可能便于指向 proteostasis 对待人的混乱的治疗学的开发。 | Tao Yu Yonghui Tao Meiqiang Yang Peng Chen Xiaobo Gao Yanbo Zhang Tao Zhang Zi Chen Jian Hou Yan Zhang Kangcheng Ruan Hongyan Wang Ronggui Hu | 2014 | Cell Research2014，24，10： | 2 |
| 2 | Inhibition of foodborne pathogens by Hf-1, a novel antibacterial peptide from the larvae of the house-fly ( Musea domestica) in medium and orange juice 显示文摘 | Hou Lixia Shi Yonghui | 2007 | Food Control2007，18，： | 1 |
| 3 | NbCl5 as an Efficient Catalyst for Rapid Synthesis of Quinoxaline Derivatives显示文摘 | HOU Juntao LIU Yonghui ZHANG Zhanhui | 2010 | J Heterocycl Chem2010，47，： | 1 |
| 4 | Hot deformation behavior and processing map of Mg-2Zn-1Al-0.2RE alloy显示文摘In this study,uniaxial hot compression tests were carried out between 200 and 400℃ over strain rates of0.001-1 s-1 to investigate the hot deformation behavior of Mg-2 Zn-1 Al-0.2 RE alloy with coarse grains.The average activation energy was measured to be 174.51 kJ/mol.In addition,a constitutive relation based on the Arrhenius equation was established.Dynamic recrystallization(DRX) kinetics were studied by Avrami equation to characterize the evolution of DRX volume fraction.DRX was favored at high temperatures of 300-400℃ and low strain rates of 0.001-0.01 s-1.According to dynamic material model and Prasad’s instability criterion,a maximum power dissipation of 38% and 32% occurs at 400℃/0.001 s-1 and 400℃/0.01 s-1,respectively.According to the proce ssing map,330-400℃/0.001-0.01 s-1was determined as the optimum deformation parameter range. | Yanxia Niu Jian Hou Fangkun Ning Xingrui Chen Yonghui Jia Qichi Le | 2020 | Journal of Rare Earths2020，38，6： | 1 |
| 5 | Antibacterial activity and in vitro anti - tumor activity of the extract of the larvae of the housefly (Musca domestica ) 显示文摘 | Lixia Hou Yonghui Shi Pei Zhai | 2007 | Journal of Ethnopharmacology2007，111，2： | 1 |
| 6 | Antibacterial activity and in vitro anti-tumor activity of the extract of the larvae of the housefly显示文摘 | Lixia Hou Yonghui Shi Pei Zhai | 2007 | J Ethnopharmacol2007，111，2： | 1 |
| 7 | Inhibition of foodborne pathogens by Hf-1, a novel antibacterial peptide from the larvae of the housefly ( Musca domestica ) in medium and orange juice显示文摘 | Lixia Hou Yonghui Shi Pei Zhai Guowei Le | 2006 | Food Control2006，，11： | 1 |
| 8 | Ambient Temperature and Years of Life Lost:A National Study in China显示文摘Although numerous studies have investigated premature deaths attributable to temperature,effects of temperature on years of life lost(YLL)remain unclear.We estimated the relationship between temperatures and YLL,and quantified the YLL per death caused by temperature in China.We collected daily meteorological and mortality data,and calculated the daily YLL values for 364 locations(2013–2017 in Yunnan,Guangdong,Hunan,Zhejiang,and Jilin provinces,and 2006–2011 in other locations)in China.A time-series design with a distributed lag nonlinear model was first employed to estimate the location-specific associations between temperature and YLL rates(YLL/100,000 population),and a multivariate meta-analysis model was used to pool location-specific associations.Then,YLL per death caused by temperatures was calculated.The temperature and YLL rates consistently showed U-shaped associations.A mean of 1.02(95%confidence interval:0.67,1.37)YLL per death was attributable to temperature.Cold temperature caused 0.98 YLL per death with most from moderate cold(0.84).The mean YLL per death was higher in those with cardiovascular diseases(1.14),males(1.15),younger age categories(1.31 in people aged 65–74 years),and in central China(1.34)than in those with respiratory diseases(0.47),females(0.87),older people(0.85 in people R75 years old),and northern China(0.64)or southern China(1.19).The mortality burden was modified by annual temperature and temperature variability,relative humidity,latitude,longitude,altitude,education attainment,and central heating use.Temperatures caused substantial YLL per death in China,which was modified by demographic and regional characteristics. | Tao Liu Chunliang Zhou Haoming Zhang Biao Huang Yanjun Xu Lifeng Lin Lijun Wang Ruying Hu Zhulin Hou Yize Xiao Junhua Li Xiaojun Xu Donghui Jin Mingfang Qin Qinglong Zhao Weiwei Gong Peng Yin Yiqing Xu Jianxiong Hu Jianpeng Xiao Weilin Zeng Xing Li Siqi Chen Lingchuan Guo Zuhua Rong Yonghui Zhang Cunrui Huang Yaodong Du Yuming Guo Shannon Rutherford Min Yu Maigeng Zhou Wenjun Ma | 2021 | The Innovation2021，2，1： | 1 |
| 9 | Surface plasmon enhanced solar-blind photoresponse of Ga2O3 film with Ga nanospheres显示文摘Semiconductor solar-blind(220-280 nm)photodetectors(PDs),which have important applications both in civil and military aspects,are mainly based on diamond[1],Al Ga N[2],Mg Zn O[3],and Ga_2O_3[4-11].Among these materials,Ga_2O_3has a direct band gap(~4.9 e V)just falling in solarblind spectral range,which makes Ga_2O_3a desirable candidate for solar-blind photodetection.Up to now,many kinds of Ga_2O_3PDs have been demonstrated including bulk[4,5],film[6-8]and nanostructures[9-11],as summarized in Table 1.From the summary,we can see although bulk | Shujuan Cui Zengxia Mei Yaonan Hou Muhua Sun Quansheng Chen Huili Liang Yonghui Zhang Xuedong Bai Xiaolong Du | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，10： | 0 |
| 10 | Design and implementation of the CAPS receiver显示文摘In this paper, based on analyses of the Chinese Area Positioning System (CAPS) satellite (GEO satellite) resources and signal properties, the signal power at the port of the receiver antenna is estimated, and the implementation projects are presented for a switching band C to band L CAPS C/A code receiver integrated with GPS receiver suite and for a CAPS dual frequency P code receiver. A microstrip receiving antenna is designed with high sensitivity and wide beam orientation, the RF front end of the C/A code and P code receivers, and a processor is designed for the navigation baseband. A single frequency CAPS C/A code receiver and a CAPS dual frequency P code receiver are built at the same time. A software process flow is provided, and research on relatively key techniques is also conducted, such as signal searching, code loop and carrier loop algorithms, a height assistant algorithm, a dual frequency difference speed measurement technique, a speed measurement technique using a single frequency source with frequency assistance, and a CAPS time correcting algorithm, according to the design frame of the receiver hardware. Research results show that the static plane positioning accuracy of the CAPS C/A code receiver is 20.5-24.6 m, height accuracy is 1.2-12.8 m, speed measurement accuracy is 0.13-0.3 m/s, dynamic plane positioning accuracy is 24.4 m, height accuracy is 3.0 m, and speed measurement accuracy is 0.24 m/s. In the case of C/A code, the timing accuracy is 200 ns, and it is also shown that the positioning accuracy of the CAPS precise code receiver (1σ ) is 5 m from south to north, and 0.8 m from east to west. Finally, research on positioning accuracy is also conducted. | HU YongHui HUA Yu HOU Lei WEI JingFa WU JianFeng | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，3： | 0 |
| 11 | Dynamic State Estimation of Power Systems with Uncertainties Based on Robust Adaptive Unscented Kalman Filter显示文摘In this paper,a robust adaptive unscented Kalman filter(RAUKF)is developed to mitigate the unfavorable effects derived from uncertainties in noise and in the model.To address these issues,a robust M-estimator is first utilized to update the measurement noise covariance.Next,to deal with the effects of model parameter errors while considering the computational complexity and real-time requirements of dynamic state estimation,an adaptive update method is produced.The proposed method is integrated with spherical simplex unscented transformation technology,and then a novel derivative-free filter is proposed to dynamically track the states of the power system against uncertainties.Finally,the effectiveness and robustness of the proposed method are demonstrated through extensive simulation experiments on an IEEE 39-bus test system.Compared with other methods,the proposed method can capture the dynamic characteristics of a synchronous generator more reliably. | Dongchen Hou Yonghui Sun Jianxi Wang Linchuang Zhang Sen Wang | 2023 | Journal of Modern Power Systems and Clean Energy2023，11，4： | 0 |
| 12 | The Binarity of Early-type Stars from LAMOST medium-resolution Spectroscopic Survey显示文摘Massive binaries play significant roles in many fields.Identifying massive stars,particularly massive binaries,is of great importance.In this paper,by adopting the technique of measuring the equivalent widths of several spectral lines,we identified 9382 early-type stars from the LAMOST medium-resolution survey and divided the sample into four groups,T1(~O-B4),T2(~B5),T3(~B7)and T4(~B8-A).The relative radial velocities RVrelwere calculated using Maximum Likelihood Estimation.The stars with significant changes of RVreland at least larger than 15.57 km s-1 were identified as spectroscopic binaries.We found that the observed spectroscopic binary fractions for the four groups are 24.6%±0.5%,20.8%±0.6%,13.7%±0.3%and 7.4%±0.3%,respectively.Assuming that orbital period(P)and mass ratio(q)have intrinsic distributions as f(P)∝Pπ(1 | Yanjun Guo Jiao Li Jianping Xiong Jiangdan Li Luqian Wang Heran Xiong Feng Luo Yonghui Hou Chao Liu Zhanwen Han Xuefei Chen | 2022 | Research in Astronomy and Astrophysics2022，22，2： | 0 |
| 13 | The Jiao Tong University Spectroscopic Telescope Project显示文摘The Jiao Tong University Spectroscopic Telescope(JUST)is a 4.4-meter f/6.0 segmented-mirror telescope dedicated to spectroscopic observations.The JUST primary mirror is composed of 18 hexagonal segments,each with a diameter of 1.1 m.JUST provides two Nasmyth platforms for placing science instruments.One Nasmyth focus fits a field of view of 10′and the other has an extended field of view of 1.2°with correction optics.A tertiary mirror is used to switch between the two Nasmyth foci.JUST will be installed at a site at Lenghu in Qinghai Province,China,and will conduct spectroscopic observations with three types of instruments to explore the dark universe,trace the dynamic universe,and search for exoplanets:(1)a multi-fiber(2000 fibers)medium-resolution spectrometer(R=4000-5000)to spectroscopically map galaxies and large-scale structure;(2)an integral field unit(IFU)array of 500 optical fibers and/or a long-slit spectrograph dedicated to fast follow-ups of transient sources for multi-messenger astronomy;(3)a high-resolution spectrometer(R~100000)designed to identify Jupiter analogs and Earth-like planets,with the capability to characterize the atmospheres of hot exoplanets. | JUST Team Chengze Liu Ying Zu Fabo Feng Zhaoyu Li Yu Yu Hua Bai Xiangqun Cui Bozhong Gu Yizhou Gu Jiaxin Han Yonghui Hou Zhongwen Hu Hangxin Ji Yipeng Jing Wei Li Zhaoxiang Qi Xianyu Tan Cairang Tian Dehua Yang Xiangyan Yuan Chao Zhai Congcong Zhang Jun Zhang Haotong Zhang Pengjie Zhang Yong Zhang Yi Zhao Xianzhong Zheng Qingfeng Zhu Xiaohu Yang | 2024 | Astronomical Techniques and Instruments2024，1，1： | 0 |
| 14 | Hyparillums A and B: polycyclic polyprenylated acylphloroglucinols from Hypericum patulum显示文摘Hyparillums A(1)and B(2),two previously unidentified polycyclic polyprenylated acylphloroglucinols(PPAPs)with intricate architectures,were isolated from Hypericum patulum Thunb.Hyparillum A was the first PPAP with eight-carbon rings based on an unprecedented 6/6/5/6/6/5/6/4 octocyclic system featuring a rare heptacyclo[10.8.1.11,10.03,8.08,21.012,19.014,17]docosane core.In contrast,hyparillum B featured a novel heptacyclic architecture(6/6/5/6/6/5/5)based on a hexacyclo[9.6.1.11,9.03,7.07,18.011,16]nonadecane motif.Furthermore,hyparillums A and B demonstrated promising inhibitory effects on the proliferation of murine splenocytes stimulated by anti-CD3/anti-CD28 monoclonal antibodies and lipopolysaccharide,exhibiting half-maximal inhibitory concentration(IC50)values ranging from 6.13±0.86 to 12.69±1.31μmol·L−1. | DUAN Yulin SHI Zhengyi SONG Fei HOU Zhangrong TAN Xiaosheng ZHANG Yeting HAO Xincai CHEN Gang QI Changxing ZHANG Yonghui | 2024 | Chinese Journal of Natural Medicines2024，22，3： | 0 |
| 15 | Very Short-Term Probabilistic Prediction Method for Wind Speed Based on ALASSO-Nonlinear Quantile Regression and Integrated Criterion显示文摘To enhance the performance of the prediction intervals (PIs), a novel very short-term probabilistic prediction method for wind speed via nonlinear quantile regression (NQR) based on adaptive least absolute shrinkage and selection operator (ALASSO) and integrated criterion (IC) is proposed. The ALASSO method is studied for shrinkage of output weights and selection of variables. Furthermore, for the better performance of PIs, composite weighted linear programming (CWLP) is proposed to modify the conventional linear programming cost function of quantile regression (QR), by combining it with Bayesian information criterion (BIC) as an IC to optimize the coefficients of PIs. Then, the multiple fold cross model (MFCM) is utilized to improve the PIs performance. Multistep probabilistic prediction of 15-minute wind speed is performed based on the real wind farm data from the northeast of China. The effectiveness of the proposed approach is validated through the performances' comparisons with conventional methods. | Yan Zhou Yonghui Sun Sen Wang Linquan Bai Dongchen Hou Rabea Jamil Mahfoud Peng Wang | 2023 | CSEE Journal of Power and Energy Systems2023，9，6： | 0 |
| 16 | 3-12 Investigation of Optical Properties of Cu/Ni Multilayer Nanowires Embedded in Etched Ion-track Template显示文摘Due to the increasing applications in optical devices electronics and nanosensors[1], 1D nanomaterials are becoming the extensive research area of physics, chemistry, medical, electronics and biology. As a member of 1D nanostructured materials, the multilayer nanowires exhibit special properties and have strong potential applications in the fields of optoelectronic devices and nanosensors [2]. | Xie Lu Yao Huijun Duan Jinglai Chen Yonghui Liu Jie Sun Youmei Hou Mingdong | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
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