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| 1 | Impact of HBV replication in peripheral blood mononuclear cell on HBV intrauterine transmission显示文摘 | Xiaohong Shi Xuefei Wang Xixi Xu Yongliang Feng Shuzhen Li Shuying Feng Bo Wang Suping Wang | 2017 | Frontiers of Medicine2017，11，4： | 11 |
| 2 | Facile synthesis of hierarchical Na2Fe(SO4)2@rGO/C as high-voltage cathode for energy density-enhanced sodium-ion batteries显示文摘Fe-based sulfates are ideal cathode candidates for sodium-ion batteries(SIBs) owing to their high operating voltage and low cost but suffer from the nature of poor power performance. Herein, a hierarchical porous Na2Fe(SO4)2@reduced graphene oxide/carbon dot(Na2Fe(SO4)2@rGO/C) with low carbon content(4.12 wt%) was synthesized via a facile homogeneous strategy benefiting for engineering application,which delivers excellent sodium storage performance(high voltage plateau of 3.75 V, 85 m Ah g-1 and330 Wh kg-1 at 0.05 C;5805 W kg-1 at 10 C) and high Na+diffusion coefficient(1.19 × 10-12 cm2 s-1).Moreover, the midpoint voltage of assembled full cell could reach 3.0 V. The electron transfer and reaction kinetics are effectively boosted since the nanoscale Na2Fe(SO4)2 is supported by a robust crosslinked carbon matrix with rGO sheets and carbon dots. The slight rGO sheets sufficiently enhance the electron transfer like a current collecter and restrain the aggregation, as well as ensure smooth ion channels. Meanwhile, the carbon dots in the whole space connect with Na2Fe(SO4)2 and help rGO to promote the conductivity of the electrode. Ex-situ X-ray powder diffraction and X-ray photoelectron spectrometry analysis confirm the high reversibility of this sodiation/desodiation process. | Ge Yao Xixue Zhang Yongliang Yan Jiyu Zhang Keming Song Juan Shi Liwei Mi Jinyun Zheng Xiangming Feng Weihua Chen | 2020 | Journal of Energy Chemistry2020，29，11： | 3 |
| 3 | Regulation of U6 Promoter Activity by Transcriptional Interference in Viral Vector-Based RNAi显示文摘The direct negative impact of the transcriptional activity of one component on the second one in cis is referred to as transcriptional interference (TI). U6 is a type III RNA polymerase III promoter commonly used for driving small hairpin RNA (shRNA) expression in vector-based RNAi. In the design and construction of viral vectors, multiple transcription units may be arranged in close proximity in a space-limited vector. Determining if U6 promoter activity can be affected by TI is critical for the expression of target shRNA in gene therapy or loss-of-function studies. In this research, we designed and implemented a modified retroviral system where shRNA and exogenous gene expressions were driven by two independent transcriptional units. We arranged U6 promoter driving shRNA expression and UbiC promoter in two promoter arrangements. In primary macrophages, we found U6 promoter activity was inhibited by UbiC promoter when in the divergent arrangement but not in tandem. In contrast, PKG promoter had no such negative impact. Instead of enhancing U6 promoter activity, CMV enhancer had significant negative impact on U6 promoter activity in the presence of UbiC promoter. Our results indicate that U6 promoter activity can be affected by TI in a proximal promoter-specific and arrangement-dependent manner. | Linghu Nie Meghna Das Thakur Yumei Wang Qin Su Yongliang Zhao Yunfeng Feng | 2010 | Genomics, Proteomics & Bioinformatics2010，8，3： | 3 |
| 4 | A Multifunctional Lentiviral-Based Gene Knockdown with Concurrent Rescue that Controls for Off-Target Effects of RNAi显示文摘The efficient, stable delivery of siRNA into cells, and the appropriate controls for non-specific off-target effects of siRNA are major limitations to functional studies using siRNA technology. To overcome these drawbacks, we have developed a single lentiviral vector that can concurrently deplete endogenous gene expression while expressing an epitope-tagged siRNA-resistant target gene in the same cell. To demonstrate the functional utility of this system, we performed RNAi-depleted α-actinin-1 (α-ACTN1) expression in human T cells. α-ACTN1 RNAi resulted in inhibited chemotaxis to SDF-1α, but it can be completely rescued by concurrent expression of RNAi-resistant α-ACTN1 (rr-α-ACTN1) in the same cell. The presence of a GFP tag on rr-α-ACTN1 allowed for detection of appropriate subcellular localization of rr-α-ACTN1. This system provides not only an internal control for RNAi off-target effects, but also the potential tool for rapid structure-function analyses and gene therapy. | Yunfeng Feng Linghu Nie Meghna Das Thakur Qin Su Zhenfen Chi Yongliang Zhao Gregory D. Longmore | 2010 | Genomics, Proteomics & Bioinformatics2010，8，4： | 2 |
| 5 | Could gingko foliage serve as a bio-monitor for organochlorine pesticides in air?显示文摘The feasibility of gingko (Gingo Biloba) foliage as a passive bio-monitor for organochlorine pesticides in air was explored. The accumulation patterns of hexachlorocyclohexanes (HCHs), dichlorodiphenyl- trichloroethanes (DDTs) and hexachlorobenzene (HCB) in gingko foliage were similar; the amounts of HCHs, DDTs and HCB increased with foliage growth in spring and decreased thereafter. This accumu-lation pattern is likely related to the growing process of the gingko foliage, which was observed for the first time in our work, giving a piece of evidence for the 'bud burst effect' in plants. Compared with those in pine needles in 1980's, the residual levels of HCHs and DDTs have declined obviously in Bei-jing, indicating that the ban on the production and use of organochlorine pesticides (OCPs) in our country is effective; however, the amount of HCB has increased, indicating great progress of chemical industry in Beijing. The analysis for the source of OCPs in the gingko foliage showed that the technical HCHs and DDTs were used largely in history, but were not used in recent years. A little lidane has been used and there was a new input of o,p′-DDT in recent years; dicofol usage may be the main source of o,p′-DDT. Concentrations of HCHs, DDTs and HCB in gingko foliages were similar to those in pine nee-dles in the corresponding period and there is a strong positive correlation between the OCPs concen-tration data obtained from these two kinds of trees. It presents no difference in the accumulation style between these two kinds of trees. The level of OCPs in the gingko foliage reflects the pollution status of OCP in air. The result of this work shows that the gingko foliage can be used as a bio-monitor of OCPs in air. | DAI TianYou ZHU XiaoHua MENG Wei YU YunJiang WANG Wei LI FaSheng LIU Feng YANG YongLiang WU DaNian | 2008 | Science China Chemistry2008，51，11： | 2 |
| 6 | Enhancement of strength-ductility balance of heavy Ti and Al alloyed FeCoNiCr high-entropy alloys via boron doping显示文摘As one of the most effective mechanisms,precipitation-hardening is widely used to strengthen high-entropy alloys.Yet,heavy precipitation-hardened high-entropy alloys usually exhibit serious embrittlement.How to effectively achieve ultra-high strength and maintain reliable ductility remains a challenge.Here,we report a study of doping extremely little boron to meet this target.We found that adding of 30 ppm boron into the heavy Ti and Al alloyed FCC FeCoNiCr high-entropy,(FeCoNiCr)_(88) Ti_(6) Al_(6) HEA(at.%)which is strengthened mainly by both coarse BCC-based(Ni,Co)_(2) TiAl Heusler and fine L12-type FCC-based(Ni,Co)_(3) TiAl precipitates and shows ultrahigh strength but poor ductility,could significantly change the original microstructure and consequently improve mechanical performance,owing to the well-known effect of boron on reducing the energy of grain boundaries.The boron addition can(1)eliminate microcavities formed at Heusler precipitate-matrix interfaces;(2)suppress the formation and segregation of coarse BCC Heusler precipitates;(3)promote the formation of L12 nanoparticles.This changes of microstructure substantially improve the tensile ductility more than by~86%and retain comparable or even better ultimate tensile strength.These findings may provide a simple and costless solution to produce heavy precipitation-strengthened HEAs with ultrahigh strength and prevent accidental brittleness. | Yongliang Qi Tinghui Cao Hongxiang Zong Yake Wu Lin He Xiangdong Ding Feng Jiang Shenbao Jin Gang Sha Jun Sun | 2021 | Journal of Materials Science & Technology2021，，16： | 2 |
| 7 | Parallel induction of cell proliferation and inhibition of cell differentiationin hepatic progenitor cells by hepatitis B virus X gene显示文摘 | Jiayi Huang Lihong Shen Yongliang Lu Hongli Li Xifeng Zhang Daixi Hu Tao Feng Fangzhou Song | 2012 | International Journal of Molecular Medicine2012，，4： | 1 |
| 8 | Coupling between finite volume method and lattice Boltzmann method and its application to fluid flow and mass transport in proton exchange membrane fuel cell显示文摘 | Li Chen Huibao Luan Yongliang Feng Chenxi Song Ya-Ling He Wen-Quan Tao | 2012 | International Journal of Heat and Mass Transfer (-)2012，，13： | 1 |
| 9 | Virtual simulation-based evaluation of ground handling for future aircraft concepts显示文摘 | TIAN Yongliang LIU Hu FENG Haocheng | 2013 | Journal of aerospace information systems2013，10，5： | 1 |
| 10 | A cerium-doped NASICON chemically coupled poly(vinylidene fluoride-hexafluoropropylene)-based polymer electrolyte for high-rate and high-voltage quasi-solid-state lithium metal batteries显示文摘The isolated inorganic particles within composite polymer electrolytes(CPEs) are not correlated to the Li^(+)transfer network,resulting in the polymer dominating the low ionic conductivity of CPEs.Therefore,we developed novel quasi-solid-state CPEs of a Ce-doped Na super ion conductors(NASICON)Na_(1.3+x)Al_(0.3)Ce_(x)Ti_(1.7-x)(PO_(4))_(3)(NCATP) chemically coupled poly(vinylidene fluoride-hexafluoropropylene)(PVDF-HFP)/Li-bis(trifluoromethanes-ulfonyl)imide(LiTFSI) matrix.A strong interaction between Ce^(3+)from NCATP and TFSI-anion from the polymer matrix contributes to the fast Li+transportation at the interface.The PVDF-HFP/NCATP CPEs exhibit an ionic conductivity of 2.16 × 0^(-3) S cm^(-1) and a Li^(+) transference number of 0.88.A symmetric Li/Li cell with NCATP-integrated CPEs at 0.1 mA cm^(-2) presents outstanding cycling stability over 2000 h at 25℃.The quasi-solid-state Li metal batteries of Li/CPEs/LiFePO_(4) at 2 C after 400 cycles and Li/CPEs/LiCoO_(2) at 0.2 C after 120 cycles deliver capacities of 100 and 152 mAh g^(-1) at 25℃,respectively. | Tao Huang Wei Xiong Xue Ye Zhencheng Huang Yuqing Feng Jianneng Liang Shenghua Ye Jishou Piao Xinzhong Wang Yongliang Li Xiangzhong Ren Chao Chen Shaoluan Huang Xiaoping Ouyang Qianling Zhang Jianhong Liu | 2022 | Journal of Energy Chemistry2022，31，10： | 1 |
| 11 | Geometrically Nonlin- ear Forced Vibrations of the Symmetric Rectangular Honey- comb Sandwich Panels with Completed Clamped Supported Boundaries 显示文摘 | Li Yongqiang Li Feng He Yongliang | 2011 | Composite Structures2011，93，： | 1 |
| 12 | Improved two-stage CMA-based blind receivers for joint equalization and mul- tiuser detection显示文摘 | Feng He Gunawan E Yongliang Guan | 2012 | IET Communications2012，2012，： | 1 |
| 13 | Cumulative summation analysis of learning curve for robot‐assisted gastrectomy in gastric cancer显示文摘 | Junfeng Zhou Yan Shi Feng Qian Bo Tang Yingxue Hao Yongliang Zhao Peiwu Yu | 2015 | J. Surg. Oncol2015，，6： | 1 |
| 14 | Robotic gastrectomy versus laparoscopic gastrectomy for gastric cancer: comparison of surgical performance and short-term outcomes显示文摘 | Zhou Junfeng Shi Yan Tang Bo Hao Yingxue Zeng Dongzhu Zhao Yongliang Qian Feng Yu Peiwu | 2014 | Surgical Endoscopy2014，，6： | 1 |
| 15 | Effect of Different Rare-Earth on Microstructure and Properties of α-Sialon Ceramics显示文摘Densified Yb-,Y-,Dy-,Sm- and Nd-α-Sialon ceramics were prepared by two-step hot sintering.The variation of microstructure and properties with different rare-earth was investigated.The ceramics doped with smaller cations (Yb^(3+),y^(3+) and Dy^(3+)) are fully composed ofα-Sialon,while in the larger cations (Sm^(3+) and Nd^(3+)) doped ceramics also exist a few intergranular phase M′(Re_2Si_(3-x)Al_xO_(3+x)N_(4-x)) in triple-point pockets.With increasing the radius of the rare-earth cations,the elongatedα-Sialon grains form instead of the equiaxed grains in Yb-α-Sialon,and the aspect ratio of grains increases.All the ceramics possess high hardness and the value of 21 GPa is achieved for Yb- and Y-α-Sialon.With increasing the ionic size of rare-earth the hardness decreases slightly but the toughness tends to increase.Nd-α-Sialon possesses the highest toughness with the value of 5.4 MPa.m^(1/2). | Chunfeng LIU Feng YE Yu ZHOU Yongliang WANG Jiancun RAO | 2008 | Journal of Materials Science & Technology2008，24，6： | 1 |
| 16 | Effect of New Fly Maggot Protein Feed on mRNA Expression of TOR Signaling Pathway-related Genes in Loaches (Misgurnus anguillicaudatus)显示文摘[Objectives] This study was conducted to explore the effects of new fly maggot protein feed on the mRNA expression of genes related to the TOR signaling pathway in loaches(Misgurnus anguillicaudatus). [Methods] Two kinds of test feed with equal nitrogen and energy were prepared by replacing 60% of the fish meal in the control group with the new fly maggot protein feed, i.e., Diet1(control group) and Diet2(60% fish meal replacement group). The feeding experiment was carried out in an indoor circulating water system, and the breeding period was 60 d. [Results] For the livers, the mRNA levels of TOR and 4EBP1 in the Diet2 group were significantly higher than those in the Diet1 group(P<0.05), while the expression of 4 EBP2 was lower than in the Diet1 group(P<0.05);and as to the muscles, the mRNA levels of TOR and 4EBP1 in the Diet2 group were significantly lower than those in the Diet1 group(P<0.05), while there was no significant change in the mRNA level of 4EBP2 between the two groups. [Conclusions] The replacement of fish meal by fly maggot cultures affected the mRNA expression of TOR, 4EBP1 and 4EBP2 in loach livers and muscles. | Haitao ZHANG Yunlong LI Yongliang CHEN Kailang GU Feng GAO | 2021 | Agricultural Biotechnology2021，10，1： | 0 |
| 17 | Experimental Investigation of Lower Hybrid Wave Coupling in HT-7显示文摘Experiments on lower hybrid wave(LHW)coupling were investigated in the HT-7 tokamak.Good coupling of LHW plasma has been demonstrated at different conditions in the HT-7 tokamak.Relevant results have proved that LHW-plasma coupling is affected by the phase difference between adjacent waveguides.Furthermore,the edge density around the grill and relevant coupling can be adjusted by changing the plasma line average density or the gap value between the LH grill and the last closed flux surfaces(LCFS).It is found that the coupling of LHWs becomes poor when the edge density around the LH grill is large enough in the HT-7tokamak,and that coupling remains good with a proper edge density.With increasing LHW power,it is also found that the reflection coefficients(RCs)increase due to non-linear effects under conditions of low edge recycling,but can decrease under high edge recycling.The edge density depends mainly on the competition between the ponderomotive force(PMF)and the edge recycling intensity in the HT-7 tokamak. | KONG Erhua DING Bojiang ZHANG Ting QIN Yongliang SHAN Jiafang LIU Fukun LI Miaohui ZHANG Lei WANG Mao LIU Liang XU Handong JIA Hua WU Zege FENG Jianqiang ZHAO Lianmin YANG Yong | 2013 | Plasma Science and Technology2013，15，10： | 0 |
| 18 | Solar Observation with the Fourier Transform Spectrometer.II.Preliminary Results of Solar Spectrum near the CO 4.66μm and Mg I 12.32μm显示文摘An infrared solar spectrum observed by ground-based telescopes is seriously affected by the background radiation both from the telescope and sky,relative to the visible wavelengths.Its accuracy is also influenced by the spectral resolution of the Fourier transform spectrometer.In the paper,we developed a CO_(2)gas cell and installed it in the sample compartment to calibrate the spectral resolution of the Bruker IFS-125HR at infrared wavelengths.The measured spectral resolution is 0.00342±0.00086 cm^(-1)and 0.0059±0.00024 cm^(-1)at the wavenumbers of798 cm^(-1)and 2136 cm^(-1),respectively.We also updated a fully reflective sunlight feeding system to observe the solar spectrum near CO 4.66μm and Mg I 12.32μm.By quickly pointing the sunlight feeding system about1 degree away from the solar disk center,we are able to measure the background radiation from the telescope and the sky at Huairou Solar Observing Station.After removing the background radiation,our observed solar spectrum at CO 4.66μm is consistent with that from the National Solar Observatory.The Mg I 12.32μm working line selected by the Accurate Infrared Magnetic Field Measurements of the Sun(AIMS)project is also identified.Our method is helpful not only for the spectral resolution calibration and background radiation correction of AIMS but also for other infrared astronomical telescopes. | Xianyong Bai Zhiwei Feng Zhiyong Zhang Yuanyong Deng Xiaoming Zhu Kaifan Ji Song Feng Xiao Yang Yongliang Song | 2023 | Research in Astronomy and Astrophysics2023，23，12： | 0 |
| 19 | New process for treating boron-bearing iron ore by flash reduction coupled with magnetic separation显示文摘Boron is an important industrial raw material often sourced from minerals containing different compounds that cocrystallize,which makes it difficult to separate the mineral phases through conventional beneficiation.This study proposed a new treatment called flash reduction-melting separation(FRMS)for boron-bearing iron concentrates.In this method,the concentrates were first flash-reduced at the temperature under which the particles melt,and the slag and the reduced iron phases disengaged at the particle scale.Good reduc-tion and melting effects were achieved above 1550℃.The B_(2)O_(3) content in the separated slag was over 18wt%,and the B content in the iron was less than 0.03wt%.The proposed FRMS method was tested to investigate the effects of factors such as ore particle size and tem-perature on the reduction and melting steps with and without pre-reducing the raw concentrate.The mineral phase transformation and morphology evolution in the ore particles during FRMS were also comprehensively analyzed. | Qipeng Bao Lei Guo Hong Yong Sohn Haibin Zuo Feng Liu Yongliang Gao Zhancheng Guo | 2024 | International Journal of Minerals,Metallurgy and Materials2024，31，3： | 0 |
| 20 | Pyropia haitanensis polysaccharide extends lifespan by inhibiting protein aggregation in Caenorhabditis elegans显示文摘Pyropia haitanensis polysaccharide(LP)have been found for having many excellent functions such as anti-aging.Using Caenorhabditis elegans models,we evaluated the anti-aging activity of LP by observing the lifespan,reproduction,pharyngeal pumping,stress response,quantitative fluorescence of polyglutamic acid,and nuclear localization of DAF-16 of worms.The results reveal that LP could extend the adult lifespan of wild-type and polyQ nematodes,indicating a connection of its anti-aging benefit with the toxicity-suppressing effect.The number of polyglutamic acid aggregates in high concentration groups decreased by 24.39%(P<0.05)to the control.The high-dose group strongly induced DAF-16 nuclear translocation over intermediate and cytosolic localizations compared with the control(P<0.001).Therefore,we believe that LP could extend the lifespan and reduce the protein aggregation in C.elegans through nuclear DAF-16∷GFP expression. | Zhongshan ZHANG Xiaomei WANG Yongliang PAN Zhanqi WANG Zhengshun WEN Feng LIU Genxiang MAO | 2021 | Journal of Oceanology and Limnology2021，39，2： | 0 |
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