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| 1 | Relationship between the imaging features and pathologic alteration in hepatoma of rats显示文摘AIM: The imaging features of MRI and DSA, using the modelsof implanted and induced hepatoma, were investigated in rats.METHODS: CBRH3 cancer cells were implanted for differentliver site of rat liver and the diethylnitrosoamine was givenorally to rats in order to induce liver cancer. Both experimentalgroups were detected by magnetic resonance imaging (MRI),digital subtraction angiography (DSA) and morphologic assay.RESULTS: Hypointensity on T1WI and homogenous highsignal intensity on T2WI in MRI, and ring-like abnormal stainon DSA were found in implanted cancer. Induced cancersappeared as homogeneous or heterogeneous hypointensityon T1WI (10 cases), and equal or slight high intensity onT2WI (8 cases), but some as hypointensity on T2WI (2 cases).CONCLUSION: The imaging features of implanted cancerswere similar to that of human liver metastases. Therefore, itcould serve as an experimental model of human liver metastatictumor. The imaging feature of induced cancers, whereas, weresimilar to that of human primary liver cancer. It could be useas an experimental model of human primary liver cancer. | Jia-He Yang Tian-Geng You Nan Li Qi-Jun Qian Ping Wang Zhen-Lin Yan Meng-Chao Wu Eastern Heptobiliary Hospital,225 Changhai Road,Shanghai 200433,China | 2003 | World Journal of Gastroenterology2003，9，1： | 13 |
| 2 | Dasycarine, a New Quinoline Alkaloid from Dictamnus dasycarpus显示文摘Dasycarine, a new quinoline alkaloid along with five known compounds, dictamine, dihydroobacunone, obacunone, fraxinellone and β-sitosterol, were isolated from Dictamnus dasycarpus. The structure of dasycarine was identified as 4, 5, 8- trimethoxyl -3- (3- methyl -2- butenyl)- 2- quinone by 1D and 2D NMR techniques. | Jin CHEN Jing Sheng TANG Jun TIAN You Ping WANG Feng E WU | 2000 | Chinese Chemical Letters2000，11，8： | 7 |
| 3 | A unified algorithm for mobility load balancing in 3GPP LTE multi-cell networks显示文摘3GPP long term evolution (LTE) is a promising candidate for the next-generation wireless network, which is expected to achieve high spectrum efficiency by using advanced physical layer techniques and flat network structures. However, the LTE network still faces the problem of load imbalance as in GSM/WCDMA networks, and this may cause significant deterioration of system performance. To deal with this problem, mobility load balancing (MLB) has been proposed as an important use case in 3GPP self-organizing network (SON), in which the serving cell of a user can be selected to achieve load balancing rather than act as the cell with the maximum received power. Furthermore, the LTE network aims to serve users with different quality-of-service (QoS) requirements, and the network-wide objective function for load balancing is distinct for different kinds of users. Thus, in this paper, a unified algorithm is proposed for MLB in the LTE network. The load balancing problem is first formulated as an optimization problem with the optimizing variables being cell-user connections. Then the complexity and overhead of the optimal solution is analyzed and a practical and distributed algorithm is given. After that, the proposed algorithm is evaluated for users with different kinds of QoS requirements, i.e., guaranteed bit rate (GBR) users with the objective function of load balance index and non-GBR (nGBR) users with the objective function of total utility, respectively. Simulation results show that the proposed algorithm leads to significantly balanced load distribution for GBR users to decrease the new call blocking rate, and for nGBR users to improve the cell-edge throughput at the cost of only slight deterioration of total throughput. | WANG Hao LIU Nan LI ZhiHang WU Ping PAN ZhiWen YOU XiaoHu | 2013 | Science China(Information Sciences)2013，56，2： | 7 |
| 4 | A novel approach for one-step forming ε-caprolactam from cyclohexane nitrozation catalyzed by transition metal salt显示文摘The nitrozation reaction of cyclohexane in one-step reaction to form ε-caprolactam has been studied using transition metal salt as catalysts in this work. The results indicated that the catalysts play an especially important role. This method is expected to be a novel way to synthesize other lactam by similar reaction. The possible mechanism was suggested. | Li Qiu Mao Bo Hua Wu Du Lin Yin Kui Yi You Ping Le Liu He An Luo | 2007 | Chinese Chemical Letters2007，18，3： | 6 |
| 5 | Lifetime maximization routing with network coding in wireless multihop networks显示文摘In this paper, we consider the lifetime maximization routing with network coding in wireless mul- tihop networks. We first show that lifetime maximization with network coding is different from pure routing, throughput maximization with network coding and energy minimization with network coding. Then we formulate lifetime maximization problems in three different cases of (i) no network coding, (ii) two-way network coding, and (iii) overhearing network coding. To solve these problems, we use flow augmenting routing (FA) for the first case, and then extend the FA with network coding (FANC) by using energy minimized one-hop network coding. After that, we investigate the influence of parameters of FANC, evaluate the performance of FANC with two-way and overhearing network coding schemes and compare it with that without network coding under two different power control models, namely, protocol and physical ones. The results show that the lifetime can be improved significantly by using network coding, and the performance gain of network coding decreases with the increase of flow asymmetry and the power control ability. | DING LiangHui WU Ping WANG Hao PAN ZhiWen YOU XiaoHu | 2013 | Science China(Information Sciences)2013，56，2： | 6 |
| 6 | Abnormal Effective Connectivity of the Anterior Forebrain Regions in Disorders of Consciousness显示文摘A number of studies have indicated that disorders of consciousness result from multifocal injuries as well as from the impaired functional and anatomical connectivity between various anterior forebrain regions.However, the specific causal mechanism linking these regions remains unclear. In this study, we used spectral dynamic causal modeling to assess how the effective connections(ECs) between various regions differ between individuals. Next, we used connectome-based predictive modeling to evaluate the performance of the ECs in predicting the clinical scores of DOC patients. We found increased ECs from the striatum to the globus pallidus as well as from the globus pallidus to the posterior cingulate cortex, and decreased ECs from the globus pallidus to the thalamus and from the medial prefrontal cortex to the striatum in DOC patients as compared to healthy controls.Prediction of the patients' outcome was effective using the negative ECs as features. In summary, the present study highlights a key role of the thalamo-basal ganglia-cortical loop in DOCs and supports the anterior forebrain mesocircuit hypothesis. Furthermore, EC could be potentially used to assess the consciousness level. | Ping Chen Qiuyou Xie Xiaoyan Wu Huiyuan Huang Wei Lv Lixiang Chen Yequn Guo Shufei Zhang Huiqing Hu You Wang Yangang Nie Ronghao Yu Ruiwang Huang | 2018 | Neuroscience Bulletin2018，34，4： | 4 |
| 7 | PI3-K/PKB/NF-κB and p42/44 MAPK pathway mediates inhibition of lipoxin A_4 on CTGF-induced production of RANTES in mesangial cells显示文摘In order to investigate the regulatory role of connective tissue growth factor (CTGF) on production of RANTES (regulated on activation, normal T cell expressed and secreted) in rat glomerular mesangial cells, and the modulatory effect of lipoxin A4(LXA4) on action of CTGF, and to explore the mechanisms of action of CTGF and LXA4, cultured rat mesangial cells were treated with CTGF, with or without preincubation with LXA4. Expression of mRNA was analyzed by RT-PCR. Protein of RANTES in the supernatants was determined by ELISA. Monocyte transmigration was assessed by in vitro chemotaxis assay. Expression of p42/44 mitogen-activated protein kinase (MAPK), phosphoinositide 3-kinase (PI3-K) and protein kinase B (PKB) was assessed by Western blotting. DNA-binding activity of nuclear factor-κB (NF-κB) was determined by electrophoretic mobility shift assay (EMSA). To observe whether transfection of LXA4 receptor homologue gene (LRHG) into mesangial cells intensified these modulatory effects of LXA4, mesangial cells were transfected with pcDNA3.1/LRHG vector. The results showed that CTGF enhanced the mRNA expression and protein release of RANTES, and the expression of phospho (P)-p42/44 MAPK, P-PI3-K, P-PKB and NF-κB. P-p42/44 MAPK blockade inhibited the CTGF-induced expression of P-p42/44 MAPK and partially decreased the level of RANTES in supernatants. P-PI3-K blockade downregulated the CTGF-stimulated expression of P-PI3-K, P-PKB and NF-κB, and partially decreased the release of RANTES. NF-κB blockade abrogated the CTGF-activated NF-κB and partially decreased the secretion of RANTES. LXA4 dose-dependently inhibited the CTGF-stimulated above action. Transfection of LRHG into mesangial cells intensified these inhibitory effects of LXA4 on CTGF-induced release of RANTES and expression of the P-p42/44 MAPK. In conclusion, LXA4 inhibits CTGF-induced production of RANTES via PI3-K/PKB/NF-κB and p42/44 MAPK-dependent signal pathway, which is mediated by LRHG in rat mesangial cells. | SHENG HUA WU CHAO LU LING DONG Guo PING ZHOU XIN You JIANG | 2005 | Journal of Microbiology and Immunology2005，3，3： | 3 |
| 8 | Imatinib plasma trough concentration and its correlation with characteristics and response in Chinese CML patients显示文摘 | Qiu-bai LI Chao CHEN Zhi-chao CHEN Hong-xiang WANG Yan-lin WU Yong YOU Ping ZOU | 2010 | Acta Pharmacologica Sinica2010，31，8： | 3 |
| 9 | Three novel opportunistic scheduling algorithms in CoMP-CSB scenario显示文摘Coordinated scheduling/beamforming(CSB),which belongs to the coordinated multi-point(CoMP) transmission,has received lots of attention recently due to its great potential to mitigate inter-cell interference(ICI) and to increase the cell-edge throughput,and meanwhile it only requires limited base station cooperation and is easy to implement.However,to the best of our knowledge,there are no effective scheduling algorithms with low complexity and overhead in CoMP-CSB scenario as yet.Thus,in this paper,we propose three novel opportunistic scheduling algorithms in CoMP-CSB scenario.All of them jointly consider the intended channel condition of the scheduled user from its serving cell and the orthogonality between the intended channel and the corresponding interference channels to concurrently scheduled users in nearby cells,thus exploiting multi-user diversity(MUD) and mitigating ICI at the same time.Algorithm 1 cooperatively chooses the most orthogonal user pair within a candidate user set in which all users have a large local channel feedback,while Algorithm 2 concurrently schedules the user pair with the largest ratio between the local channel feedbacks and the aforementioned orthogonality within the same candidate user set.Algorithm 3 performs in the way similar to the proportional fairness scheduling,while making a proper modification for its usage in CoMP-CSB scenario.The performance of the proposed scheduling algorithms are evaluated through simulation.Results show that,they all can significantly enhance the received signal to interference plus noise ratio(SINR) with relatively good fairness guarantee,thus achieving larger throughputs and utilities than several well-known scheduling algorithms.Algorithm 2 even outperforms Algorithm 1 when the aforementioned candidate user set is big enough in size and has a bit more overhead/complexity.Furthermore,Algorithms 3 is the best one among all the three proposed algorithms,but it requires more overhead/complexity than Algorithm 1 and 2.Finally,we give the optimal parameter for all of the three proposed algorithms,which can make a good tradeoff between performance and overhead/complexity. | WANG Hao LIU Nan WU Ping PAN ZhiWen YOU XiaoHu | 2013 | Science China(Information Sciences)2013，56，8： | 2 |
| 10 | Double-bullet radioimmunotargeting therapy in 31 patients with primary liver cancer显示文摘Doublebuletradioimmunotargetingtherapyin31patientswithprimarylivercancerWUYingDe1,ZHOUDeNan2,GANGYouQuan2,HUXiaoHua1,LIZ... | WU Ying De 1, ZHOU De Nan 2, GANG You Quan 2, HU Xiao Hua 1, LI Zhi Ge 1, SONG Xiang Qun 1, HE Hai Ping 2, YANG Ke Zheng 1 and HUANG Bing Yan 1 1Department of Chemotherapy, Affiliated Cancer Hospital, Guangxi Medical University, | 1997 | World Journal of Gastroenterology1997，3，3： | 2 |
| 11 | Assessing the genetic diversity of the critically endangered Chinese sturgeon Acipenser sinensis using mitochondrial markers and genome-wide single-nucleotide polymorphisms from RAD-seq显示文摘As a living fossil, the endangered Chinese sturgeon(Acipenser sinensis) has been considered a national treasure in China. Here,the famous Gezhouba Dam and Three Gorges Dam on the Yangtze River were built in 1988 and 2006, for economic purposes.The natural population of Chinese sturgeon has declined since then, as these dams block its migratory route to the original spawning grounds in the middle reaches of the Yangtze River. In 2013 and 2014, there was an absence of spawning where it typically happened near the Gezhouba Dam. Nevertheless, from April to June in 2015, over 1,000 larvae with different body lengths(10–35 cm) were detected along the Shanghai Yangtze Estuary; but only little is currently known about the population genetic structure of the Chinese sturgeon. Herein, we inferred population genetic parameters from 462 available Chinese sturgeon specimens based on a 421-bp fragment of the mitochondrial DNA(mtDNA) D-loop region and 1,481,620 SNPs(singlenucleotide polymorphisms) generated by restriction site-associated DNA sequencing(RAD-seq). For the D-loop dataset, 15 haplotypes were determined. Randomly picked 23 individuals, representing the 15 D-loop haplotype groups, were subsequently used for further RAD-seq validation. The average nucleotide diversity calculated from the mtDNA and RAD datasets was 0.0086 and 0.000478, respectively. The overall effective female population size was calculated to be 1,255 to 2,607, and the long-term effective population size was estimated to range from 11,950 to 119,500. We observed that the genetic variability and the effective female population size of the current population in the Yangtze River are severely low, which are similar to the data reported over 10 years ago. The deduced relatively small effective population of female fish, limiting the genetic connectivity among Chinese sturgeon, should be considered a serious threat to this endangered species. | Jian Liu Xinxin You Pao Xu Ping Zhuang Yueping Zheng Kai Zhang Min Wang Yunyun Lv Gangchun Xu Feng Zhao Jianhui Wu Houyong Fan Jianan Xu Zhiqiang Ruan Chao Bian Kai Liu Dongpo Xu Jinhui Chen Junmin Xu Qiong Shi | 2018 | Science China(Life Sciences)2018，61，9： | 2 |
| 12 | Binding pancreaticojejunostomy: 150 consecutive cases without leakage显示文摘 | Shu You Peng M.D. Yi Ping Mou M.D. Yin Bin Liu M.D. Ying Su M.D. Cheng Hong Peng M.D. Xiu Jun Cai M.D. Yu Lian Wu M.D. Lin Hua Zhou M.D | 2003 | Journal of Gastrointestinal Surgery2003，，7： | 2 |
| 13 | Current Status and Prospect of Stent Placement for May-Thurner Syndrome显示文摘Stent implantation has been proven to be safe and has become the first-line intervention for May-Thumer syndrome(MTS),with satisfactory mid-term patency rates and clinical outcomes.Recent research has demonstrated that catheter-directed thrombolysis is the preferred strategy when MTS is combined with deep vein thrombosis after self-expanding stent placement.However,the stent used for the venous system was developed based on the experience obtained in the treatment of arterial disease.Consequently,relatively common corresponding complications may come along later,which include stent displacement,deformation,and obstruction.Different measures such as adopting a stent with a larger diameter,improving stent flexibility,and increasing stent strength have been employed in order to prevent these complications.The ideal venous stent is presently being evaluated and will be introduced in detail in this review. | Qin LIU Fang LIU Ping LÜ Hong-xiao WU Pin YE Yun YOU Zhong YAO | 2021 | Current Medical Science2021，41，6： | 2 |
| 14 | A new 3-(3,4-methylenedioxyphenyl)-propane-1,2-diol glycoside from the roots of Cinnamomum camphora显示文摘新 3-(3,4-methylenedioxyphenyl )-propane-1,2-diol glycoside,和二已知的混合物, 3-(3,4-methylenedioxyphenyl )-propane-1,2-diol (2 ) 和 taxifolin (3 ) ,命名 cinnamomdiol A (1 ) 从 Cinnamomum camphora 的根被孤立。他们的结构根据分光镜的证据被决定。混合物 2 和 3 第一次从标题植物被孤立。 | Rui Jiang Zhong Lin You Wu Wei Xiong Er Lei Xie Guo Ping Zhou Dong Ming Zhang | 2011 | Chinese Chemical Letters2011，22，8： | 2 |
| 15 | A preliminary research establishing the present-time intraplate blocks movement model on the Chinese mainland based on GPS data显示文摘 | Shuo-Yu Zhou Yue-Gang Zhang Guo-Yu Ding Yun Wu Xiao-Jun Qin Shun-Ying Shi Qi Wang Xin-Zhao You Xue-Jun Qiao Ping Shuai Gan-Jin Deng | 1998 | Acta Seismologica Sinica1998，，4： | 1 |
| 16 | Primary isolated hepatic oval cells maintain progenitor cell phenotypes after two-year prolonged cultivation显示文摘 | Ping Wang Min Cong Tian-Hui Liu Ai-Ting Yang Rui Cong Peng Wu Shu-Zhen Tang Yong Xu Hui Wang Bao-En Wang Ji-Dong Jia Hong You | 2010 | Journal of Hepatology2010，，5： | 1 |
| 17 | Large-scale synthesis of flowerlike ZnO nanostructure by a simple chemical solution route and its gas-sensing property显示文摘 | HUANG Jia Rui WU You Jie GU Cui Ping | 2010 | Sens Actuat B: Chem2010，146，1： | 1 |
| 18 | Preparation, structu re, and properties of starch/rubber composites prepared by cocoagulating rubber latex and starch paste 显示文摘 | You ping Wu Meiqin J i Qing Qi | 2004 | Macromolecular Rapid Communication2004，25，4： | 1 |
| 19 | Study on multi- agent- based agile supply chain management 显示文摘 | Ping Luo Zu - de Zhou You - Ping Chen Wu Ai | 2004 | The International Journal of Advanced Manufacturing Technology2004，23，34： | 1 |
| 20 | Recommendations for the diagnosis and treatment of paroxysmal kinesigemc dyskinesia: an expert consensus in China显示文摘Paroxysmal dyskinesias are a group of neurological diseases characterized by intermittent episodes of involuntary movements with different causes.Paroxysmal kinesigenic dyskinesia(PKD)is the most common type of paroxysmal dyskinesia and can be divided into primary and secondary types based on the etiology.Clinically,PKD is characterized by recurrent and transient attacks of involuntary movements precipitated by a sudden voluntary action.The major cause of primary PKD is genetic abnormalities,and the inheritance pattern of PKD is mainly autosomal-dominant with incomplete penetrance.The proline-rich transmembrane protein 2(PRRT2)was the first identified causative gene of PKD,accounting for the majority of PKD cases worldwide.An increasing number of studies has revealed the clinical and genetic characteristics,as well as the underlying mechanisms of PKD.By seeking the views of domestic experts,we propose an expert consensus regarding the diagnosis and treatment of PKD to help establish standardized clinical evaluation and therapies for PKD.In this consensus,we review the clinical manifestations,etiology,clinical diagnostic criteria and therapeutic recommendations for PKD,and results of genetic analyses in PKD patients performed in domestic hospitals. | Li Cao Xiaojun Huang Ning Wang Zhiying Wu Cheng Zhang Weihong Gu Shuyan Cong Jianhua Ma Ling Wei Yanchun Deng Qi Fang Qi Niu Jin Wang Zhaoxia Wang You Yin Jinyong Tian Shufen Tian Hongyan Bi Hong Jiang Xiaorong Liu Yang Lu Meizhen Sun Jianjun Wu Erhe Xu Tao Chen Tao Chen Xu Chen Wei Li Shujian Li Qinghua Li Xiaonan Song Ying Tang Ping Yang Yun Yang Min Zhang Xiong Zhang Yuhu Zhang Ruxu Zhang Yi Ouyang Jintai Yu Quanzhong Hu Qing Ke Yuanrong Yao Zhe Zhao Xiuhe Zhao Guohua Zhao Furu Liang Nan Cheng Jianhong Han Rong Peng Shengdi Chen Beisha Tang | 2021 | Translational Neurodegeneration2021，10，1： | 1 |
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