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| 1 | Buffer allocation method of serial production lines based on improved ant colony optimization algorithm显示文摘Buffer influences the performance of production lines greatly.To solve the buffer allocation problem(BAP) in serial production lines with unreliable machines effectively,an optimization method is proposed based on an improved ant colony optimization(IACO) algorithm.Firstly,a problem domain describing buffer allocation is structured.Then a mathematical programming model is established with an objective of maximizing throughput rate of the production line.On the basis of the descriptions mentioned above,combining with a two-opt strategy and an acceptance probability rule,an IACO algorithm is built to solve the BAP.Finally,the simulation experiments are designed to evaluate the proposed algorithm.The results indicate that the IACO algorithm is valid and practical. | 周炳海 Yu Jiadi | 2016 | High Technology Letters2016,22,2: | 2 |
| 2 | ACE2 expression is regulated by AhR in SARS-CoV-2-infected macaques显示文摘During the current outbreak of coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),more than 115 million people have been infected,and 2.5 million have died.1,2 Despite such great harm to human health,the pathogenesis of COVID-19 remains unclear.As the first step in the pathogenetic process,viral entry is mediated by the binding of the SARS-CoV-2 surface spike(S)protein to angiotensin-converting enzyme 2(ACE2)on host cells,such as lung epithelial cells.As an alternative to S protein-blocking strategies,manipulating host cell ACE2 expression may exert an inhibitory effect on SARS-CoV-2 infection.However,the molecular mechanism regulating ACE2 expression remains unclear. | Jiadi Lv Pin Yu Zhenfeng Wang Wei Deng Linlin Bao Jiangning Liu Fengli Li Qiangqiang Zhu Nannan Zhou Qi Lv Guanpeng Wang Shunyi Wang Yabo Zhou Jiangping Song Wei-Min Tong Yuying Liu Chuan Qin Bo Huang | 2021 | Cellular & Molecular Immunology2021,18,5: | 1 |
| 3 | Differentially Private Multidimensional Data Publication显示文摘 | ZHANG Ji DONG Xin YU Jiadi LUO Yuan LI Minglu WU Bin | 2014 | China Communications2014,11,A01: | 1 |
| 4 | CBT: A Proximity-aware Peer Clustering System in Large-scale BitTorrent-like Peer-to-Peer Networks 显示文摘 | Yu Jiadi Li Minglu | 2008 | Computer Communications2008,31,3: | 1 |
| 5 | SARS-CoV-2 treatment effects induced by ACE2-expressing microparticles are explained by the oxidized cholesterolincreased endosomal pH of alveolar macrophages显示文摘Exploring the cross-talk between the immune system and advanced biomaterials to treat SARS-CoV-2 infection is a promising strategy.Here,we show that ACE2-overexpressing A549 cell-derived microparticles(AO-MPs)are a potential therapeutic agent against SARS-CoV-2 infection.Intranasally administered AO-MPs dexterously navigate the anatomical and biological features of the lungs to enter the alveoli and are taken up by alveolar macrophages(AMs).Then,AO-MPs increase the endosomal pH but decrease the lysosomal pH in AMs,thus escorting bound SARS-CoV-2 from phago-endosomes to lysosomes for degradation.This pH regulation is attributable to oxidized cholesterol,which is enriched in AO-MPs and translocated to endosomal membranes,thus interfering with proton pumps and impairing endosomal acidification.In addition to promoting viral degradation,AO-MPs also inhibit the proinflammatory phenotype of AMs,leading to increased treatment efficacy in a SARS-CoV-2-infected mouse model without side effects.These findings highlight the potential use of AO-MPs to treat SARS-CoV-2-infected patients and showcase the feasibility of MP therapies for combatting emerging respiratory viruses in the future. | Zhenfeng Wang Jiadi Lv Pin Yu Yajin Qu Yabo Zhou Li Zhou Qiangqiang Zhu Shunshun Li Jiangping Song Wei Deng Ran Gao Yuying Liu Jiangning Liu Wei-Min Tong Chuan Qin Bo Huang | 2022 | Cellular & Molecular Immunology2022,19,2: | 1 |
| 6 | An Economy-based Accounting System for Grid Computing Environments 显示文摘 | YU Jiadi LI Minglu LI Ying | 2004 | Lecture Notes in Computer Science2004,3307,: | 1 |
| 7 | Distributed spectrum sharing in cognitive radio networks:a pricing-based decomposition approach显示文摘 | Zhu Yanmin Sun Wei Yu Jiadi | 2014 | International Journal of Distributed Sensor Networks2014,,: | 1 |
| 8 | CBT: A proximity-aware peer clustering system in large-scale BitTorrent-like peer-to-peer networks 显示文摘 | YU JIADI LI MINGLU | 2008 | Computer Communications2008,31,3: | 1 |
| 9 | Rate-aware optimal transmission power analysis in wireless ad hoc networks显示文摘The problem of transmission power control in a rate-aware way is investigated to improve the through-put of wireless ad hoc network.The behavior of basic IEEE 802.11 DCF is approximated by the p-persis-tent CSMA through a Markov chain model.The throughput model takes hidden temainals,multi-hop flowand concurrent interference into account.Numerical results show that the optimal transmission power de-rived from this model could balance the tradeoff between spatial reuse and data rate and hence yield maxi-mum throughput. | 陈琳 Li Minglu Yu Jiadi | 2008 | High Technology Letters2008,14,3: | 0 |
| 10 | 肿瘤再生细胞通过犬尿氨酸转移以及芳香烃受体激活诱导CD8^+T细胞表达PD-1显示文摘文章简介肿瘤免疫治疗是当前肿瘤研究的热点领域之一,通过利用免疫细胞、免疫分子直接或间接杀伤肿瘤细胞,以控制或清除肿瘤,被认为是人类战胜癌症的希望所在。肿瘤免疫治疗主要依赖活化的T细胞杀伤肿瘤细胞. | 刘玉英 梁晓雨 董文茜 Yi Fang Jiadi Lv Tianzhen Zhang Roland Fiskesund Jing Xie Jinyan Liu Xiaonan Yin Xun Jin Degao Chen Ke Tang Jingwei Ma Huafeng Zhang Jing Yu Jun Yan Huaping Liang Siqi Mo Feiran Cheng Yabo Zhou Haizeng Zhang Jing Wang Jingnan Li Yang Chen Bing Cui Zhuo-Wei Hu Xuetao Cao F. Xiao-Feng Qin 黄波 | 2019 | 科学新闻2019,0,2: | 0 |