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58篇 您的检索式:作者名="YuJin Liu"
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1Cryogenic 3D printing of dual-delivery scaffolds for improved bone regeneration with enhanced vascularization显示文摘Three-dimensional(3D)printing has been increasingly employed to produce advanced bone tissue engineering scaffolds with biomimetic structures and matched mechanical strengths,in order to induce improved bone regeneration in defects with a critical size.Given that the successful bone regeneration requires both excellent osteogenesis and vascularization,endowing scaffolds with both strong bone forming ability and favorable angiogenic potential would be highly desirable to induce improved bone regeneration with required vascularization.In this investigation,customized bone tissue engineering scaffolds with balanced osteoconductivity/osteoinductivity were produced via cryogenic 3D printing ofβ-tricalcium phosphate and osteogenic peptide(OP)containing water/poly(lactic-co-glycolic acid)/dichloromethane emulsion inks.The fabricated scaffolds had a hierarchically porous structure and were mechanically comparable to human cancellous bone.Angiogenic peptide(AP)containing collagen I hydrogel was then coated on scaffold surface to further provide scaffolds with angiogenic capability.A sequential release with a quick AP release and a slow but sustained OP release was obtained for the scaffolds.Both rat endothelial cells(ECs)and rat bone marrow derived mesenchymal stem cells(MSCs)showed high viability on scaffolds.Improved in vitro migration and angiogenesis of ECs were obtained for scaffolds delivered with AP while enhanced osteogenic differentiation was observed in scaffolds containing OP.The in vivo results showed that,toward scaffolds containing both AP and OP,the quick release of AP induced obvious angiogenesis in vivo,while the sustained OP release significantly improved the new bone formation.This study provides a facile method to produce dual-delivery scaffolds to achieve multiple functions.Chong Wang Jiahui Lai Kai Li Shaokui Zhu Bingheng Lu Jia Liu Yujin Tang Yen Wei 2021Bioactive Materials2021,6,1:7
2QTL analysis of ear leaf traits in maize(Zea mays L.)under different planting densities显示文摘Modem maize varieties have become more productive than ever, owing largely to increased tolerance of high plant density. However, the genetics of ear leaf traits under different densities remains poorly understood. In this study, Zhongdan 909 recombinant inbred lines(RILs) derived from a cross between Z58 and HD568 were genotyped for 3072 single-nucleotide polymorphisms(SNPs), and phenotyped for leaf length(LL), leaf width(LW), and leaf angle(LA) of the uppermost ear leaf under three planting densities(52,500,67,500, and 82,500 plants ha-1, respectively). A genetic map was then constructed using1358 high-quality SNPs. The total length of the linkage map was 1985.2 cM and the average interval between adjacent markers 1.46 cM. With increasing density, LL and LW decreased from 63.68 to 63.02 cm and from 8.56 to 8.21 cm, respectively, while LA increased from19.42° to 19.66°. All three traits had high heritabilities, of 0.75, 0.78, and 0.84, respectively.Using inclusive composite interval mapping, 23, 25, and 17 quantitative trait loci(QTL) were detected for LL, LW, and LA, respectively. Of these, 35 were simultaneously detected under two or three plant densities, while 30 were detected under only one. Sixty-five individual QTL explained 2.41% to 16.53% of phenotypic variation, while eight accounted for >10%.These findings will help us understand the genetic basis of leaf traits in maize as well as the response of maize to increased plant density.Hongwu Wang Qianjin Liang Kun Li Xiaojiao Hu Yujin Wu Hui Wang Zhifang Liu Changling Huang 2017The Crop Journal2017,5,5:7
3The Characterization, Authentication, and Gene Expression Pattern of the MdCER Family in Malus domestica显示文摘Plant cuticular wax is an important determinant factor of fruit quality. Cuticular wax can protect the fruit from UV radiation, drought, and disease and increase the storage period of fruit. In many species, CER gene is associated with wax and can affect plant response to stress, but no characterization of CER gene and its family has been reported in apples. In this study, we identified 10 MdCER genes in Malus domestica based on the sequences of 10 CER genes in Arabidopsis thaliana. Three-dimensional structures were then defined, and root-mean-square deviation(RMSD)scoring matrixes were used to evaluate the matches. These 10 genes were divided into three classes using phylogenetic methods; namely,class I, II, and III. The predicted MdCER genes were distributed across 7 out of 17 chromosomes with different densities. Furthermore, the gene structures and motif compositions of the MdCER genes were analyzed. The quantitative real-time PCR results indicated that MdCER family genes were mainly expressed in the leaves and stems and rarely in the roots. Most of the MdCER members responded to salicylic acid and polyethylene glycol treatment, indicating that the MdCER family is associated with disease resistance(biotic) and abiotic stress.Chenhui Qi Han Jiang Xianyan Zhao Ke Mao Haitao Liu Yuanyuan Li Yujin Hao 2019Horticultural Plant Journal2019,5,1:7
4Controls of Late Jurassic-Early Cretaceous tectonic event on source rocks and seals in marine sequences,South China显示文摘Thermal evolution of source rocks and dynamic sealing evolution of cap rocks are both subjected to tectonic evolution.The marine sequences in South China have experienced superposed structural deformation from multiple tectonic events.To investigate the effectiveness of preservation conditions,it is of great importance to understand the controls of key tectonic events on the dynamic evolution of cap rocks.This paper discusses the controls of Late Jurassic-Early Cretaceous(J3-K1) tectonic event on source and cap rocks in marine sequences in South China based on the relationships between J3-K1 tectonic event and the burial history types of the marine sequences,the hydrocarbon generation processes of marine source rocks,the sealing evolution of cap rocks,the preservation of hydrocarbon accumulations,and the destruction of paleo-oil pools.The study has the following findings.In the continuously subsiding and deeply buried areas during the J3-K1 period,marine source rocks had been generating hydrocarbons for over a long period of time and hydrocarbon generation ended relatively late.At the same time,the sealing capacity of the overburden cap rocks had been constantly strengthened so that hydrocarbons could be preserved.In the areas which suffered compressional deformation,folding and thrusting,uplifting and denudation in J3-K1,the burial history was characterized by an early uplifting and the hydrocarbon generation by marine source rocks ended(or suspended) during the J3-K1 period.The sealing capacity of the cap rocks was weakened or even vanished.Thus the conditions for preserving the hydrocarbon accumulations were destroyed.The continuously subsiding and deeply buried areas during the J3-K1 period are the strategic precincts of the petroleum exploration in marine sequences in South China.JIN ZhiJun YUAN YuSong LIU QuanYou WO YuJin 2013Science China Earth Sciences2013,56,2:6
5Seasonal variations and bioavailability of inorganic phosphorus in soils of Yeyahu Wetland in Beijing,China显示文摘Phosphorus(P) in soils has an important influence on the development and productivity of wetland. The objective of this study was to investigate the distribution,bioavailability and seasonal variations of inorganic phosphorus(IP) in soils of Yeyahu Wetland.The results showed that the concentration of Ca-bound P(Ca-P) remained the main occurrence in all IP fractions despite the season,at the same time the Al-bound P(Al-P) was always the lowest IP fraction despite the season.Al-P and Fe-bound P (Fe-P) concentration were all reached the highest value in May and the lowest in November,which was opposite to the occluded P(Oc-P) fraction.The notable higher Oc-P concentration in November observed in this study was probably due to the decomposition of plants and the subsequently releasing of oxides to soils.Ca-P didn't change much with season variations.Exchangeable P(Ex-P) and Oc-P were all positively correlated with soil moisture content and organic matter content,but Al-P was negatively correlated with these two soil properties.As a stable form,Ca-P was not associated with soil properties.Al-P,Fe-P and Ca-P might contribute to the storage of P in studied wetland with the principle component analysis results.The concentration rank order of the bio-available P in soils was generally as follows:Olsen-P > Algal available P(AAP) > Water soluble P(WSP) > Readily desorbed P(RDP).Olsen-P was positively correlated with Ex-P and Oc-P,and it was thought to be a more suitable indicator for bio-available P in soils.ZHANG Jing LI Min LIU Shuang LIU Yujin ZHANG Liqiang CAO Qi SUN Dezhi 2011International Journal of Sediment Research2011,26,2:4
6Geochemical Characteristics and Geological Significance of Meta-Volcanic Rocks of the Bainaimiao Group, Sonid Right Banner, Inner Mongolia, China显示文摘The Bainaimiao Group, which crops out in the Sonid Right Banner area of Inner Mongolia, China, comprises mainly metamorphosed volcano-sedimentary rocks. This group can be divided into two formations: a lower formation characterized by intermediate-felsic volcanic rocks, and an upper formation of intermediate-mafic volcanic rocks. Zircon dating indicates that biotite leptynite from the lower formation and chlorite-sericite schist from the upper formation crystallized at 499±2 and 478±2 Ma, respectively, corresponding to different volcanic events. Meta-volcanic rocks of the Bainaimiao Group belong to the calcalkaline series, and the SiO2 concentrations suggest that their protoliths were mainly basalts and rhyolites. Greenschist rocks of the group are enriched in light rare earth elements(LREEs) relative to heavy rare earth elements(HREEs), with(La/Yb)N ratios of 3.08–10.9. In addition, they are enriched in large-ion lithophile elements, including Rb, Ba and K, and depleted in the high-field-strength elements Nb, Ta and Ti. The felsic meta-volcanic rocks also exhibit relative enrichments in LREEs compared with HREEs, with high(La/Yb)N ratios of 2.92–9.89, and are enriched in Rb, Ba, Zr and Hf, and depleted in Sr, Nb and Ta. These geochemical characteristics indicate that the meta-basic volcanic rocks were originated from partial melting of sub-arc mantle wedge that had been previously metasomatized by subducted-slab-derived fluids, whereas the meta-felsic volcanic rocks were generated by partial melting of continental crust. These results suggest that the meta-volcanic rocks of the Bainaimiao Group are the products of oceanic plate subduction magmatism along an active continental margin, which can be attributed to Early Paleozoic subduction of the PaleoAsian Ocean plate beneath the northern margin of the North China Craton.Chao Zhang Jingyu Quan Zhenghong Liu Zhongyuan Xu Xuejiao Pang Yujin Zhang 2019Journal of Earth Science2019,30,2:4
7Functional Characterization of the Apple RING E3 Ligase MdMIEL1 in Transgenic Arabidopsis显示文摘E3 ubiquitin ligases are involved in various physiological processes,and they play pivotal roles in growth and development.In this study,we identified a previously unknown gene in the apple fruit(Malus×domestica)and named it MdMIEL1.The MdMIEL1 gene encoded a protein that contained a zinc-finger domain at its N-terminus and a RING-finger motif at its C-terminus.To investigate MdMIEL1 functions,we generated transgenic Arabidopsis lines expressing the MdMIEL1 gene under the control of the Cauliflower mosaic virus 35S promoter.Interestingly,ectopic expression of MdMIEL1 in Arabidopsis produced multiple phenotypes,including early germination,early flowering and a lateral root number increase relative to wild-type plants.Further analysis indicated that MdMIEL1 regulated lateral root initiation by increasing auxin accumulation in the roots.In a word,these results suggest that,MdMIEL1 as a novel RING-finger ubiquitin ligase influences plant growth and development,and highlight that MdMIEL1 regulates lateral root growth.AN Jianping LIU Xin SONG Laiqing YOU Chunxiang WANG Xiaofei HAO Yujin 2017Horticultural Plant Journal2017,3,2:3
8Genome-Wide Identification, Characterization, and Expression Analysis of Calmodulin-Like Proteins(CMLs) in Apple显示文摘Calcium(Ca^(2+)), a crucial second messenger in plants, is involved in diverse signaling pathways including biotic and abiotic stress responses. However, the functions of most calcium sensors including calcium-dependent protein kinases(CDPKs), calmodulins(Ca Ms), calmodulinlike proteins(CMLs), and calcineurin B-like proteins(CBLs) remain limited in plants, particularly in woody plants. Currently, a total of 83 CMLs and seven Ca Ms were discovered in the apple genome in this study. Functional domain analysis showed that these CMLs and Ca Ms contain a highly conserved EF-hand motif. q RT-PCR assays indicated that these CMLs were expressed ubiquitously in apple, including in the roots, stems,leaves, flowers, and fruits, and also possessed spatial specificity. Finally, most of these CMLs were induced by hormonal and abiotic stress, suggesting their potential roles in the regulation of growth, development, and the stress response in apple. In summary, our findings provide potential evidence that apple CMLs may be involved in abiotic stress and the regulation of plant growth and development.ZHANG Quanyan LIU Xiaojuan LIU Xin WANG Jiahui YU Jianqiang HU Dagang HAO Yujin 2017Horticultural Plant Journal2017,3,6:3
9Regulation of impedance matching feature and electronic structure of nitrogen-doped carbon nanotubes for high-performance electromagnetic wave absorption显示文摘In this study,we developed a facile method to fabricate three-dimensional(3D)structures composed of FeNi alloy nanoparticles encapsulated in N-doped carbon nanotubes that grafted on the SiO_(2) spheres(Fe_(x)Ni_(y)@NCNT@SiO_(2))for electromagnetic wave(EMW)absorption.The experimental results suggest that the impedance matching characteristic can be tuned by the introduction of SiO_(2) spheres in the 3D structure.Density functional theory(DFT)calculations showed that the introduction of Ni improved the polarization and conductive losses of the Fe_(x)Ni_(y)@NCNT@SiO_(2).As a result,the optimal 3D structure exhibits excellent EMW absorption property with a reflection loss and effective absorption bandwidth are-49.39 dB and 4.32 GHz,respectively,even though the matching thickness is only 1.6 mm,superior to most magnetic carbon-based composites.Thus,our current approach opens up an effective way to the development of low-cost,high-performance EMW absorbers.Fenghui Cao Jia Xu Minjie Liu Feng Yan Qiuyun Ouyang Xitian Zhang Xiaoli Zhang Yujin Chen 2022Journal of Materials Science & Technology2022,,13:3
10Effect of cytotoxic T-lymphocyte antigen-4,TNF-alpha polymorphisms on osteosarcoma: evidences from a meta-analysis显示文摘Objective:Previous studies have investigated the role of cytotoxic T-lymphocyte antigen-4(CTLA-4)and tumor necrosis factor-alpha(TNF-α)in carcinogenesis of osteosarcoma,but their results were inconsistent.We aimed to clarify the associations between CTLA-4,TNF-αpolymorphism and osteosarcoma risk by using meta-analysis.Methods:We searched relevant studies without language restriction in PubMed,EMbase,Cochrane Library,Google Scholar databases,Chinese National Knowledge Infrastructure(CNKI)and conference literature in humans published prior to March 2013.The strengths of the associations between genetic variants and osteosarcoma risk were estimated by odds ratio(OR)with 95%confidence interval(95%CI).Results:A total of seven studies with 1,198 osteosarcoma patients and 1,493 controls were selected.Four studies were eligible for CTLA-4(1,003 osteosarcoma and 1,162 controls),and three studies for TNF-α(195 osteosarcoma and 331 controls).Pooled results showed that rs231775 polymorphism of CTLA-4 was associated with osteosarcoma risk(GG vs.AA:OR=1.63,95%CI=1.24-2.13;GG+GA vs.AA:OR=1.56,95%CI=1.21-2.01;AA+GA vs.GG:OR=0.83,95%CI=0.71-0.97;G vs.A:OR=1.21,95%CI=1.08-1.36).No significant heterogeneity was observed across the studies.No significant associations were found between rs5742909 polymorphism of CTLA-4 or rs1800629 polymorphism of TNF-αand osteosarcoma risk.Conclusions:These results suggest that the rs231775 polymorphism of CTLA-4 may play an important role in carcinogenesis of osteosarcoma.Jianwei Liu Junli Wang Weiping Jiang Yujin Tang 2013Chinese Journal of Cancer Research2013,25,6:3
11Genetic analysis and QTL mapping of stalk cell wall components and digestibility in maize recombinant inbred lines from B73 × By804显示文摘The cell wall composition and structure of the maize stalk directly affects its digestibility and in turn its feed value.Previous studies of stem quality have focused mostly on common maize germplasm,and few studies have focused on high-oil cultivars with high grain and straw quality.Investigation of the genetic basis of cell wall composition and digestibility of maize stalk using high-oil maize is desirable for improving maize forage quality.In the present study,a high-oil inbred line(By804)was crossed as male parent with the maize inbred line B73 to construct a population of 188 recombinant inbred lines(RILs).The phenotypes of six cell-wall-related traits were recorded,and QTL analysis was performed with a genetic map constructed with SNP markers.All traits were significantly correlated with one another and showed high broad-sense heritability.Of 20 QTLs mapped,the QTL associated with each trait explained 10.0%–41.1%of phenotypic variation.Approximately half of the QTL each explained over 10%of the phenotypic variation.These results provide a theoretical basis for improving maize forage quality by marker-assisted selection.Qi Wang Kun Li Xiaojiao Hu Huimin Shi Zhifang Liu Yujin Wu Hongwu Wang Changling Huang 2020The Crop Journal2020,8,1:2
12A New Species of Coniopteris moguqiensis sp. nov. from the Middle Jurassic Wanbao Formation in Eastern Inner Mongolia, China显示文摘In recent years, an increasing number of plant fossil leaves and petrified woods have been discovered from the Middle Jurassic Wanbao Formation in Moguqi Town of Inner Mongolia, NE China. Here, we describe a new species of Coniopteris moguqiensis sp. nov. preserved as a fragment with fertile and sterile pinnules. The sterile ultimate pinnules are elongate ovate with sphenopteriod type venation, and fertile pinnules are usually isolated, bipinnate at least with the sorus apical, elliptical, 1 mm in diameter;sporangia are almost globular, 100-150 μm in diameter, and the annulus is vertical. In situ spores are rounded-triangular in polar view, 25-30 μm in diameter with sides straight and slightly convex;trilete, laesurae are thin and slightly straight;the exine surface is usually psilate under the light microscope but finely reticuloid sculptured on the proximal view under a scanning electronic microscope. The fern genus Coniopteris usually suggests a warm and humid environment, which is consistent with the palaeoclimatic conditions of petrified wood and megafossil plants. The new discovery further supplements the floral composition of the Wanbao Formation, providing new material for understanding the evolutionary trend and classification of Coniopteris.ZHANG Yujin LIU Bingcai LIANG Fei 2019Acta Geologica Sinica(English Edition)2019,93,5:2
13Purification and Identification of Antioxidant Peptides from the Scallop Skirts of Mimachlamys Nobilis显示文摘The processes of scallop meats can produce a large amount of by-products like scallop skirts,which are rich in nutrients. This work aimed to obtain the information about antioxidant peptides derived from scallop skirts of Mimachlamys nobilis. The hydro-lysates obtained by trypsin exhibited the highest antioxidant activity( 75.6%,79.5% and 76.7% using DPPH,hydroxyl and superoxide anion radical scavenging activity assays,respectively). The antioxidant peptides( MNAP) were separated and purified using UF membranes,GFC processes and RP-HPLC,and the antioxidant activity of MNAP was identified to be 85.7% using DPPH radical scavenging activity assay. The peptides( MNAP) were composed of two peptides with their molecular weights2 855.6 Da and 3 007.2 Da using MALDI-TOF-MS,respectively. The results suggested that the scallop skirts of Mimachlamys nobilis could be explored as a source of antioxidant peptides.Quanfu Wang Yifan Wang Yanhua Hou Yifeng Xu Meihong Yan Haoyuan Li Yuanping Liu Yujin Li 2017Journal of Harbin Institute of Technology(New Series)2017,24,5:1
14All-inorganic lead-free NiO_(x)/Cs_(3)Bi_(2)Br_(9) perovskite heterojunction photodetectors for ultraviolet multispectral imaging显示文摘Bismuth-based perovskites are considered to be promising candidates to substitute the toxic lead-based perovskite in optoelectronics due to their excellent optoelectronic properties,high environmental friendliness,and(moisture,light,and heat)stability.However,there are still few reports about high performance bismuth-based perovskite ultraviolet photodetectors,and is more lacking in ultraviolet imaging demonstration.Herein,we reported a self-powered NiO_(x)/Cs_(3)Bi_(2)Br_(9) heterojunction photodetector with excellent photodetection performance by electrochemical depositing NiOx as the hole transport layer.The optimized NiO_(x)/CsaBi_(2)Brg heterojunction photodetector exhibits excellent ultraviolet detection performance with a fast response speed of 3.04/4.65 ms,wide linear dynamic range of 116.6 dB,decent responsivity of 4.33 mA·W^(-1) at 0 V bias,and high detectivity of 1.3×10^(11) jones.The outstanding performance of the optimized NiO_(x)/Cs_(3)Bi_(2)Br_(9) heterojunction photodetector is enough to meet the high-quality ultraviolet imaging.Therefore,we further integrated the optimized NiO_(x)/Cs_(3)Bi_(2)Br_(9) heterojunction photodetector to the transmission mode ultraviolet multispectral imaging system,achieving admirable imaging results at weak light condition.This work will play a positive role in promoting the development of bismuth-based ultraviolet photodetection and ultraviolet multispectral imaging.Yujin Liu Yuxin Gao Jingyi Zhi Rongqing Huang Wanjun Li Xinyue Huang Genghua Yan Zhong Ji Wenjie Mai 2022Nano Research2022,15,2:1
15Ultrahigh ethanol response of SnO2 nanorods at low working temperature arising from La2O3 loading 显示文摘SHI Songlin LIU Yonggang CHEN Yujin 2009Sensors Actuators B: Chem2009,140,2:1
16Microstructure, mechanical and thermo-physical properties of hot-pressed Al2O3-GdAlO3-ZrO2 ceramics with eutectic composition显示文摘A low cost chemical co-precipitation method was employed to fabricate nanoscale Al_2O_3-GdAlO_3-ZrO_2 powder with eutectic composition. A careful control of reaction conditions was required during the preparation. The synthesized nanopowders exhibited a particle size of 20-200 nm, and were highly dispersive and uniform. The results showed that calcination temperature had an important influence on the phase constituents of the nanopowders. With increasing the calcination temperature, a phase transformation from θ-Al_2O_3 to α-Al_2O_3 and a thermal decomposition from Gd_3 Al_5O_(12)(GdAG) to GdAlO_3 and α-Al_2O_3 occurred in sequence. A calcination temperature of 1300 ℃ was needed for the crystallization of α-Al_2 O_3. These nanosized powders were consolidated via hot pressing to produce a fully densified ceramic composite with eutectic composition. The Al_2O_3-GdAlO_3-ZrO_2 ceramic hot-pressed at 1500 ℃ exhibited a relative density of 99.4%, a flexural strength of 485 MPa and a fracture toughness of 6.5 MPa m^(1/2). The ceramic had a thermal conductivity of 1.9 W m K^(-1) at 1200 ℃ and a thermal expansion coefficient of 9.49 ×10^(-6) K^(-1) at 1100 ℃.Abdelkhalek Henniche Jiahu Ouyang Yonghui Ma Zhigang Wang Zhanguo Liu Yujin Wang Mehdi Derradji Xinyu Liu 2017Progress in Natural Science:Materials International2017,27,4:1
17Effects of protein oxidation, cathepsins, and various freezing temperatures on the quality of superchilled sturgeon fillets显示文摘Many aquatic products have been stored using superchilling technology, but rarely used for the storage of sturgeon fillets. In this study, we investigated the effects of protein oxidation, cathepsin, and various freezing temperatures on the quality of superchilled sturgeon fillets. Sensory evaluation results showed that the sensory attributes of superchilled (−3 °C) sturgeon fillets were acceptable three times longer (18 days) than samples stored at refrigeration temperatures (4 °C). The sarcoplasmic protein, carbonyl, myofibrillar protein, total sulfhydryl content and the surface hydrophobicity were determined using fluorescence spectrophotometry and SDS-PAGE. Results showed that superchilling might protect myofibrillar proteins from oxidation compared to refrigeration temperatures. The activity of the three cathepsins (B, L, and H) in terms of myofibrillar, mitochondria, lysosomes, and sarcoplasm demonstrated that superchilling can inhibit cathepsins activity in sturgeon and protect its muscle structure. Microscopic observations showed that as the temperature decreased, the gap area of the muscle fibers decreased, and the deformation of cross-sectional slices was gradually reduced. In addition, the freezing rate of ice crystals produced during the freezing process influenced the muscle structure, texture, and sensory attributes. Superchilled sturgeon fillets showed good hardness, chewiness, and water retention. In conclusion, superchilling technology shows promise for its ability to extend the shelf life while maintaining the texture and sensory attributes of fresh sturgeon fillets.Nana Zhao Xianqing Yang Yujin Li Haohao Wu Yiping Chen Ruichang Gao Feng Xiao Fan Bai Jinlin Wang Zunying Liu Xin Gao Yuanhui Zhao 2022Marine Life Science & Technology2022,4,1:1
18Preoperative combined with postop- erative chemoembolization can improve survival in patients with hepatocellular carcinoma: a single- center study 显示文摘YuJin Liu RenJie Yang 2009Vase [nterv Radial2009,20,4:1
19Modeling the two-phase cloud evolution from instantaneous flashing release using CFD 显示文摘TAN Wei LIU Xiao LIU Yujin 2011Journal of Loss Prevention in Process Industries2011,24,4:1
20An ultrapotent RBD-targeted biparatopic nanobody neutralizes broad SARS-CoY-2 variants显示文摘The wide transmission and host adaptation of SARS-CoV-2 have led to the rapid accumulation of mutations,posing significant challenges to the effectiveness of vaccines and therapeutic antibodies.Although several neutralizing antibodies were authorized for emergency clinical use,convalescent patients derived natural antibodies are vulnerable to SARS-CoV-2 Spike mutation.Xiaojing Chi Xinhui Zhang Shengnan Pan Yanying Yu Yujin Shi Tianli Lin Huarui Duan Xiuying Liu Wenfang Chen Xuehua Yang Lan Chen Xiaoqian Dong Lili Ren Qiang Ding Jianwei Wang Wei Yang 2022Signal Transduction and Targeted Therapy2022,7,3:1
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