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| 1 | The bulk transfer coefficients and surface fluxes on the western Tibetan Plateau显示文摘On the gradient observational data of the atmospheric surface layer from September 1997 to December 1998 collected by two sets of Automatic Weather Station (AWS) installed in Gaize and Shiquanhe on the western Tibetan Plateau, mean surface roughness lengths at the two stations above are determined to be 2.7 and 2.9 cm, respectively. The bulk transfer coefficients each day are computed by the profile-flux method, means of the bulk transfer coefficient for momentum (i.e. drag coefficient) in 1998 are 4.83×10-3 and 4.75×103 at the two stations. The surface fluxes of momentum, sensible heat and latent heat each day are further estimated by the bulk formulas, annual mean of these fluxes is 3.4×10-2 and 1.8×102N/m2, 73.1 and 67.2 W/m2, 15.4 and 2.9 W/m2, respectively. The diurnal and seasonal variations are obtained by a composite method and the relationships among the heat transfers between land and atmosphere, plateau monsoon and plateau rain season are also discussed. | Guoping Li Tingyang Duan Yuanfa Gong | 2000 | Chinese Science Bulletin2000，45，13： | 13 |
| 2 | The essential oil components of Cinnamomum cassia: an analysis under different thinning models of plantation Pinus massoniana显示文摘Thinning is an important activity employed in forest management. To date, studies have mainly focused on the effects of thinning on the growth of trees during the same thinning period. In this study, plantation Pinus massoniana Lamb. near maturity were thinned at varying intensities and an economically important species, Cinnamomum cassia Presl., was planted beneath the thinned canopy. The aim of the study was to explore the effects of the extent of thinning on the essential oil content and its components of C. cassia in different parts of the plant, as well as the economic feasibility of the P. massoniana–C.cassia management model. Thinning significantly reduced the oil yield in the bark and branches of C. cassia, but hardly impacted the oil yield from C. cassia leaves compared with pure C. cassia forest(CK). Among the different thinning treatments, both light(T.4) and extensive(T.1)thinning reduced the oil yield of C. cassia bark and new branches. The concentrations of the main aldehydes differed in different parts of the plant and were affected by the extent of thinning. The influence on cinnamaldehyde in the bark was minor, but was much greater in the branches and leaves. Both the oil yield and content of cinnamaldehyde showed that moderate(T.3) thinning was more favorable than other thinning models. These results not only provide a potentially promising model for the transformation of low–yield artificial pure forests of P. massoniana in the future, but also offer a reference for the management of artificial mixed stands. | Dayan Tao Yuanfa Li Daodiao Lu Yehong Luo Sufang Yu Shaoming Ye | 2016 | Journal of Forestry Research2016，27，3： | 5 |
| 3 | Spatial pattern dynamics among co-dominant populations in early secondary forests in Southwest China显示文摘The canopy of subtropical natural forests usually consists of several co-dominant populations(CDPs),which play a crucial role in forest structure,formation of the forest environment,and ecological function.However,little attention has been given to changes in spatial patterns in CDPs during natural succession.Cyclobalanopsis glauca(Thunb.)Oerst.,Quercus variabilis Blume,and Pinus yunnanensis var.tenuifolia W.C.Cheng & Y.W.Law are canopy species that form CDPs in zonal forests along the Nanpan River in southwest China.We used the g(r) function and its bivariate distribution model,g_(12)(r),which is based on distances between pairs of points,to explore the dynamics of the three CDP species with respect to distribution patterns and spatial correlations in two secondary forests(one 30-year-old forest [30-YF] and one 57-year-old forest [57-YF]).The following key results were obtained:(1) there was a clumped pattern in the 30-YF,but the intensity of aggregation varied among populations and life stages.The distribution pattern gradually shifted to become random with longer succes sion time(i.e.,30-YF vs.57-YF),expansion of the observation scale(r=0-20 m),and at later life stages.(2) Aside from the mid-sized C.glauca trees and large P.yunnanensis trees,the trees repulsed each other at certain scales(r=0-2,5-6,11-12,14-16 m) in the 30-YF.Almost all of the life stages in the CDPs were independently correlated.This independent correlation was exacerbated by a longer succession time.(3) An increase in life stages and longer succession also promoted independent changes in intraspecific correlations.(4) Intraspecific correlations were stronger than interspecific correlations.Our results showed that reducing exclusive competition is essential to coexistence in CDPs.Inter-and intra-specific repulsion may occur at the same time,but intraspecific repulsion was the main driving force behind the random distributions and independent correlations. | Yuanfa Li Minghui Li Angang Ming Hongxiang Wang Sufang Yu Shaoming Ye | 2021 | Journal of Forestry Research2021，32，4： | 3 |
| 4 | Spatial structure characteristics of three hardwood species in Korean pine broad-leaved forest-Validating the bivariate distribution of structural parameters from the point of tree population 显示文摘 | Li Yuanfa Hui Gangying Zhao Zhonghua | 2014 | Forest Ecology and Management2014，314，： | 1 |
| 5 | A comparison of cake properties in traditional and turbulence promoter assisted microfiltration of particulate suspensions显示文摘 | Yuanfa Liu Gaohong He Baojun Li Zhengwen Hu Jia Ju | 2012 | Water Research2012，，8： | 1 |
| 6 | Spatial structural characteristics of three hardwood species in Korean pine broad-leaved forest—Validating the bivariate distribution of structural parameters from the point of tree population显示文摘 | Yuanfa Li Gangying Hui Zhonghua Zhao Yanbo Hu Shaoming Ye | 2014 | Forest Ecology and Management2014，，： | 1 |
| 7 | The bivariate distribution characteristics of spatial structure in natural K orean pine broad‐leaved forest显示文摘 | Yuanfa Li Gangying Hui Zhonghua Zhao Yanbo Hu | 2012 | J Veg Sci2012，，6： | 1 |
| 8 | Metformin escape in prostate cancer by activating the PTGR1 transcriptional program through a novel super-enhancer显示文摘The therapeutic efficacy of metformin in prostate cancer(PCa)appears uncertain based on various clinical trials.Metformin treatment failure may be attributed to the high frequency of transcriptional dysregulation,which leads to drug resistance.However,the underlying mechanism is still unclear.In this study,we found evidences that metformin resistance in PCa cells may be linked to cell cycle reactivation.Super-enhancers(SEs),crucial regulatory elements,have been shown to be associated with drug resistance in various cancers.Our analysis of SEs in metformin-resistant(MetR)PCa cells revealed a correlation with Prostaglandin Reductase 1(PTGR1)expression,which was identified as significantly increased in a cluster of cells with metformin resistance through single-cell transcriptome sequencing.Our functional experiments showed that PTGR1 overexpression accelerated cell cycle progression by promoting progression from the G0/G1 to the S and G2/M phases,resulting in reduced sensitivity to metformin.Additionally,we identified key transcription factors that significantly increase PTGR1 expression,such as SRF and RUNX3,providing potential new targets to address metformin resistance in PCa.In conclusion,our study sheds new light on the cellular mechanism underlying metformin resistance and the regulation of the SE-TFs-PTGR1 axis,offering potential avenues to enhance metformin’s therapeutic efficacy in PCa. | Jianheng Ye Shanghua Cai Yuanfa Feng Jinchuang Li Zhiduan Cai Yulin Deng Ren Liu Xuejin Zhu Jianming Lu Yangjia Zhuo Yingke Liang Jianjiang Xie Yanqiong Zhang Huichan He Zhaodong Han Zhenyu Jia Weide Zhong | 2023 | Signal Transduction and Targeted Therapy2023，8，9： | 0 |
| 9 | Phosphatidylmannoside prevents obesity induced by high-fat feeding显示文摘Emerging evidence suggests that dietary D-mannose,enriched naturally in many plants and fruits,show benefits in patients with bacterial urinary tract infection,diabetes,and obesity.However,it is noteworthy that the physiological level of D-mannose in the blood is relatively low.Based on the study that D-mannose could be a safe and beneficial dietary supplement to obese,here phosphatidylation of mannose was proposed as a way to increase the physiological level of D-mannose and enhance the modulatory effect of mannose on obesity.In this study,phosphatidylmannoside(PtdMan)was synthesized via the approach of phospholipase D mediated transphosphatidylation.In vivo,we show that phosphatidylation of mannose enhanced the physiological level of mannose in blood.The benefits of PtdMan and D-mannose in high-fat diet-induced obesity were then investigated.Compared with D-mannose supplementary,increased physiological level of PtdMan enhanced the expression of fatty acid oxidation-related genes in liver and PPARγtargeted genes in adipose tissue,thus protecting from high-fat diet induced obesity,glucose tolerance,and insulin sensitivity.Together,our findings reveal the possibility that phosphatidylation of mannose could be used as a dietary approach to prevent obesity-associated diseases via its enhanced mannose bioavailability. | Yanjun Liu Ziwei Li Junyi Liu Jie Xu Yuanfa Liu Changhu Xue | 2022 | Food Bioscience2022，46，2： | 0 |
| 10 | Relationship between species diversity and tree size in natural forests around the Tropic of Cancer显示文摘Although numerous hypotheses have been proposed to explain the patterns of species diversity of forests at local and landscape levels,it is still difficult to predict the alpha diversity of species,especially in tropical and subtropical natural forests where trees of different sizes and shapes are highly mixed.Size might characterize species diversity,and the possible correlation between these variables may contribute to the development of easy-to-use growth indicators to predict diversity and to understand the status of trees within a stand.In this study,diameter classes were divided using the equal diameter class(EDC)and minimum measured diameter(MMD)methods,and five species diversity indices were calculated for each diameter class of 14 permanent plots in five national nature reserves surrounding the Tropic of Cancer(23.5°),southwest China.The results show that species richness,abundance,and spatial diversity indices decreased in a typical inverted J-shape pattern with increasing diameter class and MMD,and could be easily modeled by a negative exponential function.The ShannonWiener index showed a linear decrease while Pielou’s evenness index displayed a linear increase,with a small degree of instability.The results suggest that species diversity in subtropical forests is closely related to tree size,and the relationship is possibly independent of habitat.Measuring DBH of some trees in a stand could be informative regarding species diversity and contribute to the investigation and assessment of biodiversity. | Yuanfa Li Shaoming Ye Yinghua Luo Sufang Yu Gongqiao Zhang | 2023 | Journal of Forestry Research2023，34，6： | 0 |
| 11 | A novel surgical technique for dissection of Siewert typeⅡadenocarcinoma of the esophagogastric junction:the transthoracic single-port assisted laparoscopic esophagogastrostomy显示文摘Introduction The surgical approach for Siewert type II adenocarcinoma of the esophagogastric junction(AEG)is controversial.The JCOG9502 trial[1,2]has shown that the left thoracoabdominal approach has not improved the prognosis but increased the morbidity in patients with Siewert typeⅡorⅢAEG compared with the abdominal-transhiatal(TH)approach.However,lower mediastinum lymphadenectomy and digestive tract reconstruction using the laparoscopic TH approach are technically difficult[3]. | Wenjun Xiong Xiaohua Zhong Yan Chen Sijing Luo Yaohui Peng Yuanfa Hou Jin Li Yansheng Zheng Lijie Luo Ziming Cui Wei Wang | 2022 | Gastroenterology Report2022，10，1： | 0 |
| 12 | Evaluating Natural Forest Management Efficiency显示文摘According to the structure-based forest management theory,the appraisal indices system of natural forest management efficiency was established from spatial utilization,species diversity, constructive species competition and tree composition,which could be used to depict stand status,and its metewand was given.Relative weight was endowed by The Analytic Hierarchy Process (AHP),and then the conception of natural forest management efficiency comprehensive appraisal index was put forward for the first time and applied to four different sampling plots of natural forest, three of them from Dongdapo forest region,Jiaohe, Jilin province,and one from Baihua forest area, Xiaolongshan,Gansu province,China.The results are as following:the stand status was obviously improved after being managed and plot A,B got a mark of 'medium' while C and D were 'perfect'. From high to low,the arrangement of forest management efficiency comprehensive appraisal index was C>D>A>B.This appraisal result abided by the phenomenon detected in the practical field.The forest management efficiency comprehensive appraisal index brought up in this paper could be taken as a way of comprehensive quantitative change of stand state which directly reflects the effort of forest management and affords scientific basis of natural forest management effort. | Li Yuanfa Zhao Zhonghua Hu Yanbo Hui Gangying | 2012 | Chinese Forestry Science and Technology2012，11，3： | 0 |
| 13 | Early-Life Gut Microbiota Governs Susceptibility to Colitis via Microbial-Derived Ether Lipids显示文摘Localized intestine inflammation could induce short-term increases in colonic oxygenation and leads to increases in the aerobic bacteria population and reduction in the anaerobic bacteria population by changing the intestinal environment.However,the mechanisms involved and the associated functions of intestinal anaerobes in gut health still remain unclear.Here,we found that early-life depletion of gut microbiota exacerbated later colitis,while mid-life microbiota depletion showed partially reduced colitis.Notably,we observed that early-life gut microbiota depletion confers susceptibility to ferroptosis in colitis.In contrast,restitution of early-life microbiota conferred protection against colitis and inhibited ferroptosis triggered by gut microbiota dysbiosis.Similarly,colonization with anaerobic microbiota from young mice suppressed colitis.These results may attribute to high abundance of plasmalogen-positive(plasmalogen synthase[PlsA/R]-positive)anaerobes and plasmalogens(one of the common ether lipids)in young mice but reduced abundance in the development of inflammatory bowel disease.Early-life anaerobic bacteria elimination also resulted in the aggravation of colitis,while this aggravation phenotype was reverted by plasmalogen administration.Interestingly,plasmalogens inhibited ferroptosis triggered by microbiota dysbiosis.We further find that the alkenyl-ether group of plasmalogens was critical to colitis prevention and ferroptosis inhibition.These data point to one of the mechanisms by which the gut microbiota controls susceptibility to colitis and ferroptosis early in life via microbial-derived ether lipids. | Yanjun Liu Chunhua Jiao Tao Zhang Xue Li Panpan Li Meishan Lu Zhan Ye Yanpeng Du Runfeng Du Wenlong Zhang Jie Xu Zhaojun Zheng Yongjiang Xu Changhu Xue Yi Zhang Yuanfa Liu | 2023 | Research2023，，3： | 0 |
| 14 | Novel function of biguanides in inhibition of phospholipase D1 expression via a translational mechanism in cancer cells显示文摘Phospholipase D(PLD)and its product phosphatidic acid(PA)function as pleiotropic factors in the regulation of cancer progression,which includes the promotion of cell growth,survival,cell migration,and angiogenesis.1 Chemical inhibition of the enzymatic activity of PLD1 and PLD2,or genetic down-regulation of their expression both induce tumor suppression,1 while the compounds for PLD expression inhibition are barely reported.Here,we astonishingly found that the anti-hyperglycemic agents biguanides decreased PLD1 protein expression in cancer cells and further investigated its underlying regulatory mechanism. | Yuanfa Yao Hanbing Li Xinyi Wang Yuanhai Sun Xuqin Zhao Weiwei Zha Jiaqiang Zhou Derek Toomre Junfen Fu Yingke Xu | 2023 | Genes & Diseases2023，10，5： | 0 |
| 15 | Effect of Pressure on Microstructure and Mechanical Properties of AM60B Alloy Used for Motorcycle Wheels Formed by Double Control Forming显示文摘A set of novel forming die combining the advantages of dies casting and forging was designed,by which double control forming idea was firstly proposed.The motorcycle wheel made of AM60B alloy was used as the typical component to demonstrate advantages of the double control forming.The effect of pressure on the mechanical properties and microstructure of the parts formed by double control forming was investigated.The results showed that high mechanical properties and complex shape were achieved in the parts formed by double control forming.Compared to die casting,the mechanical properties of the formed part significantly increased and the microstructure changed from the coarse dendrites to fine equiaxed grains.The shrinkage voids and microcracks in the formed parts were obviously reduced or even completely eliminated with the increase of pressure.When a pressure of 4000 kN was applied,the optimal mechanical properties such as ultimate tensile strength of 265.6 MPa and elongation of 21%were achieved and the microstructure was characterized by fine and uniform equiaxed grains due to the large undercooling degree caused by the high pressure. | Jufu Jiang Yuansheng Cheng Zhiming Du Jun Liu Yuanfa Li Shoujing Luo | 2013 | Journal of Materials Science & Technology2013，29，5： | 0 |
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