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| 1 | Climatological Characteristics of Summer Precipitation over East Asia Measured by TRMM PR:A Review显示文摘Precipitation is an important indicator of climate change and a critical process in the hydrological cycle, on both the global and regional scales. Methods of precipitation observation and associated analyses are of strategic importance in global climate change research. As the first space-based radar, the Tropical Rainfall Measuring Mission(TRMM)Precipitation Radar(PR) has been in operation for almost 17 years and has acquired a huge amount of cloud and precipitation data that provide a distinctive view to help expose the nature of cloud and precipitation in the tropics and subtropics. In this paper we review recent advances in summer East Asian precipitation climatology studies based on long-term TRMM PR measurements in the following three aspects:(1) the three-dimensional structure of precipitation,(2) the diurnal variation of precipitation, and(3) the recent precipitation trend. Additionally, some important prospects regarding satellite remote sensing of precipitation and its application in the near future are discussed. | Yunfei FU Xiao PAN Yuanjian YANG Fengjiao CHEN Peng LIU | 2017 | Journal of Meteorological Research2017，31，1： | 6 |
| 2 | Cycling durability and degradation behavior of La–Mg–Ni–Co-type metal hydride electrodes显示文摘 | Yongfeng Liu Hongge Pan Yuanjian Yue Xuefeng Wu Ni Chen Yongquan Lei | 2004 | Journal of Alloys and Compounds2004，，1： | 1 |
| 3 | Relationship between Extreme Precipitation and Temperature in Two Different Regions:The Tibetan Plateau and Middle–East China显示文摘The change of extreme precipitation with temperature has regional characteristics in the context of global warming.In this study, radiosonde data, co-located rain gauge(RG) observations, and Tropical Rainfall Measuring Mission(TRMM) precipitation radar(PR) products are used to explore the relationship between extreme precipitation intensity and near-surface temperature in Middle–East China(MEC) and the eastern Tibetan Plateau(TP) during1998–2012. The results show that extreme precipitation intensity increases with increasing temperature at an approximate Clausius–Clapeyron(C–C) rate(i.e., water vapor increases by 7% as temperature increases by 1°C based on the C–C equation) in MEC and TP, but the rate of increase is larger in TP than in MEC. This is probably because TP(MEC) is featured with deep convective(stratiform) precipitation, which releases more(less) latent heat and strengthens the convection intensity on a shorter(longer) timescale. It is also found that when temperature is higher than 25°C(15°C) in MEC(TP), the extreme precipitation intensity decreases with rise of temperature, suggesting that the precipitation intensity does not always increase with warming. In this case, the limited atmospheric humidity and precipitable water could be the primary factors for the decrease in extreme precipitation intensity at higher temperatures. | Rui WANG Tao XIAN Mengxiao WANG Fengjiao CHEN Yuanjian YANG Xiangdong ZHANG Rui LI Lei ZHONG Chun ZHAO Yunfei FU | 2019 | Journal of Meteorological Research2019，33，5： | 1 |
| 4 | Recent Advances of Electrochemiluminescent System in Bioassay显示文摘Electrochemiluminescent(ECL)technique has drawn increasing attention in a myriad of applications ranging from clinic diagnosis to the environment and food monitoring.The advantages of ECL sensors include high sensitivity,negligible background,and excellent controllability with respect to its counterparts.The past 2 years have witnessed an impetus in the rise of a batch of luminophores and coreactants as advanced materials to boost the ECL efficiencies.In the review,we summarize the latest progress of new ECL biosensing systems,in particular of emerging luminophores,coreactants,and the involved mechanisms.Possible limitations and exciting future developments of the ECL biosensing are also complementarily discussed.It is highly envisioned that the review article would inspire more intriguing advances both in the fundamental research and more demanding practical applications of ECL for prospective biosensing. | Mengyuan Chen Zhenqiang Ning Kaiyang Chen Yuanjian Zhang Yanfei Shen | 2020 | Journal of Analysis and Testing2020，4，2： | 1 |
| 5 | ADMA induces monocyte adhesion via activation of chemokine receptors in cultured THP-1 cells,Contents lists available at ScienceDirect显示文摘 | MEIFANG CHEN YUANJIAN TIANLUN YANG | 2008 | Cytokine2008，43，： | 1 |
| 6 | Acidic and Basic Fibroblast Growth Factors Involved in Cardiac Angiogenesis following Infarction 显示文摘 | Tieqiang Zhao Wenyuan Zhao Yuanjian Chen | 2011 | Int J Cardiol2011，152，3： | 1 |
| 7 | A Machine Learning-based Cloud Detection Algorithm for the Himawari-8 Spectral Image显示文摘Cloud Masking is one of the most essential products for satellite remote sensing and downstream applications.This study develops machine learning-based(ML-based)cloud detection algorithms using spectral observations for the Advanced Himawari Imager(AHI)onboard the Himawari-8 geostationary satellite.Collocated active observations from Cloud-Aerosol Lidar with Orthogonal Polarization(CALIOP)are used to provide reference labels for model development and validation.We introduce both daytime and nighttime algorithms that differ according to whether solar band observations are included,and the artificial neural network(ANN)and random forest(RF)techniques are adopted for comparison.To eliminate the influences of surface conditions on cloud detection,we introduce three models with different treatments of the surface.Instead of developing independent ML-based algorithms,we add surface variables in a binary way that enhances the ML-based algorithm accuracy by~5%.Validated against CALIOP observations,we find that our daytime RF-based algorithm outperforms the AHI operational algorithm by improving the accuracy of cloudy pixel detection by~5%,while at the same time,reducing misjudgment by~3%.The nighttime model with only infrared observations is also slightly better than the AHI operational product but may tend to overestimate cloudy pixels.Overall,our ML-based algorithms can serve as a reliable method to provide cloud mask results for both daytime and nighttime AHI observations.We furthermore suggest treating the surface with a set of independent variables for future ML-based algorithm development. | Chao LIU Shu YANG Di DI Yuanjian YANG Chen ZHOU Xiuqing HU Byung-Ju SOHN | 2022 | Advances in Atmospheric Sciences2022，39，12： | 1 |
| 8 | CCL17 exerts neuroprotection through activation of CCR4/mTORC2 axis in microglia after subarachnoid haemorrhage in rats显示文摘Background and purpose C-C motif chemokine ligand 17(CCL17)presents an important role in immune regulation,which is critical in the pathophysiology of brain injury after subarachnoid haemorrhage(SAH).There is rare evidence to illustrate the function of CCL17 towards SAH.In this study,we try to reveal the therapeutic effects of CCL17 and its underlying mechanism in rat SAH model.Methods SAH rat models were assigned to receive recombinant CCL17(rCCL17)or phosphate buffer saline(PBS).AZD2098 and JR-AB2-011 were applied to investigate the C-C motif chemokine receptor 4(CCR4)/mammalian target of rapamycin complex 2(mTORC2)axis in CCL17-mediated neuroprotection.To elucidate the underlying mechanism,the in vitro kinase assay was performed in primary microglia.Microglial-specific Rictor knockdown was administered via intracerebroventricular injection of adenovirus-associated virus.Brain water content,short-term neurobehavioural evaluation,western blot analysis,quantitative RT-PCR and histological staining were performed.Results The expression of CCL17 was increased and secreted from neurons after oxyhaemoglobin stimulation.Exogenous rCCL17 significantly alleviated neuronal apoptosis,and alleviated short-term neurofunction after SAH in rats.In addition,rCCL17 increased M2-like polarisation of microglia in rats post-SAH and in primary microglia culture.The neuroprotection of rCCL17 was abolished via inhibition of either CCR4 or mTORC2.Conclusion CCL17 activated the CCR4/mTORC2 axis in microglia,which can alleviate SAH-induced neurological deficits by promoting M2-like polarisation of microglia. | Anke Zhang Yibo Liu Houshi Xu Zeyu Zhang Xiaoyu Wang Ling Yuan Cameron Lenahan Chuan Zhang Junkun Jiang Chaoyou Fang Yuanjian Fang Jianmin Zhang Sheng Chen | 2023 | Stroke & Vascular Neurology2023，8，1： | 0 |
| 9 | Modulation of long-term potentiation in the hippocampus by pharmacological approach:A novel strategy for the development of cognitive enhancers显示文摘Learning and memory not only provide the foundations of cognition, but are also closely related to sensory and motor function. Neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are accompanied by deficits in synaptic function and cognition to varying degrees. The discovery of long-term potentiation (LTP) of hippocampal synaptic transmission, which has been recognized as a classical model of learning and memory at the cellular level, has spurred substantial progress in the development of cognitive enhancers in the past 20 years. Following intensive investigations into LTP, a variety of compounds and biologically active substances have been found to modulate hippocampal LTP via numerous molecular mechanisms including regulating presynaptic neurotransmitter release, postsynaptic N-methyl D-aspartate (NMDA) receptor activity, postsynaptic signal transduction and gene transcription. This review focuses on the progress of investigations into the overarching mechanisms of LTP, the drugs modulating LTP and prospects for the development of new drugs for treating cognitive impairments in the future. | YANG YuanJian WU PengFei WANG Fang CHEN Jian Guo | 2010 | Chinese Science Bulletin2010，55，30： | 0 |
| 10 | Enhanced Differentiable Architecture Search Based on Asymptotic Regularization显示文摘In differentiable search architecture search methods,a more efficient search space design can significantly improve the performance of the searched architecture,thus requiring people to carefully define the search space with different complexity according to various operations.Meanwhile rationalizing the search strategies to explore the well-defined search space will further improve the speed and efficiency of architecture search.With this in mind,we propose a faster and more efficient differentiable architecture search method,AllegroNAS.Firstly,we introduce a more efficient search space enriched by the introduction of two redefined convolution modules.Secondly,we utilize a more efficient architectural parameter regularization method,mitigating the overfitting problem during the search process and reducing the error brought about by gradient approximation.Meanwhile,we introduce a natural exponential cosine annealing method to make the learning rate of the neural network training process more suitable for the search procedure.Moreover,group convolution and data augmentation are employed to reduce the computational cost.Finally,through extensive experiments on several public datasets,we demonstrate that our method can more swiftly search for better-performing neural network architectures in a more efficient search space,thus validating the effectiveness of our approach. | Cong Jin Jinjie Huang Yuanjian Chen Yuqing Gong | 2024 | Computers, Materials & Continua2024，78，2： | 0 |
| 11 | A Li_(3)P nanoparticle dispersion strengthened ultrathin Li metal electrode for high energy density rechargeable batteries显示文摘Achievement of lithium(Li)metal anode with thin thickness(e.g.,≤30µm)is highly desirable for rechargeable high energy density batteries.However,the fabrication and application of such thin Li metal foil electrode remain challenging due to the poor mechanical processibility and inferior electrochemical performance of metallic Li.Here,mechanico-chemical synthesis of robust ultrathin Li/Li_(3)P(LLP)composite foils(~15µm)is demonstrated by employing repeated mechanical rolling/stacking operations using red P and metallic Li as raw materials.The in-situ formed Li+-conductive Li_(3)P nanoparticles in metallic Li matrix and their tight bonding strengthen the mechanical durability and enable the successful fabrication of free-standing ultrathin Li metal composite foil.Besides,it also reduces the electrochemical Li nucleation barrier and homogenizes Li plating/stripping behavior.When matching to high-voltage LiCoO_(2),the full cell with a low negative/positive(N/P)capacity ratio of~1.5 offers a high energy density of~522 W·h·kg^(-1) at 0.5 C based on the mass of cathode and anode.Taking into account its facile manufacturing,potentially low cost,and good electrochemical performance,we believe that such an ultrathin composite Li metal foil design with nanoparticle-dispersion-strengthened mechanism may boost the development of high energy density Li metal batteries. | Lin Fu Xiancheng Wang Bao Zhang Zihe Chen Yuanjian Li Yongming Sun | 2024 | Nano Research2024，17，5： | 0 |
| 12 | Lysosomal TMEM9-LAMTOR4-controlled mTOR signaling integrity is required for mammary tumorigenesis显示文摘Dear Editor,Accumulating evidence suggests that dysregulated lysosomal membrane proteins,including vacuolar ATPase(v-ATPase)and the mammalian target of rapamycin(mTOR),are involved in tumorigenesis[1].Therefore,lysosomal proteins were proposed as potential therapeutic targets in cancer[1].As one of the lysosome-related signaling pathways,mTOR signaling regulates cell proliferation,survival,motility,and metabolism[2].SincemTOR signaling activation promotes tumorigenesis,mTOR inhibitors(mTORi),AZD8055[3],MLN0128[4],and Rapalink-1(the latest third-generation mTORi)[4],have been applied to several cancers.However,the limitations of mTORi include drug resistance and the lack of biomarkers. | Shengzhe Zhang Sung Ho Lee Litong Nie Yuanjian Huang Gengyi Zou Youn-Sang Jung Sohee Jun Jie Zhang Esther MLien Junjie Chen Jae-Il Park | 2023 | Cancer Communications2023，43，1： | 0 |
| 13 | Insight into structure evolution of carbon nitrides and its energy conversion as luminescence显示文摘A series of carbon nitride(CN)materials represented by graphitic carbon nitride(g-C3N4)have been widely used in bioimaging,biosensing,and other fields in recent years due to their nontoxicity,low cost,and high luminescent quantum efficiency.What is more attractive is that the luminescent properties such as wavelength and intensity can be regulated by controlling the structure at the molecular level.Hence,it is time to summarize the related research on CN structural evolution and make a prospect on future developments.In this review,we first summarize the research history and multiple structural evolution of CN.Then,the progress of improving the luminescence performance of CN through structural evolution was discussed.Significantly,the relationship between CN structure evolution and energy conversion in the forms of photoluminescence,chemiluminescence,and electrochemiluminescence was reviewed.Finally,key challenges and opportunities such as nanoscale dispersion strategy,luminous efficiency improving methods,standardization evaluation,and macroscopic preparation of CN are highlighted. | Hao Zhang Jingwei Zhang Wenjie Chen Minjia Tao Xianguang Meng Yuanjian Zhang Guifu Zuo | 2024 | Carbon Energy2024，6，2： | 0 |
| 14 | Beehive: low-cost content subscription service using cloudlets显示文摘In recent years, Content Subscription Service (CSS) is showing a notable success in helping users fetch unpopular data in P2P networks. It works by maintaining a storage pool to pull the subscribed file and then redistribute them to the requestor. However, existing commercial CSS incurs huge bandwidth/equipment cost due to introducing a third-party cloud storage. We present Beehive, a low-cost yet efficient CSS, which leverages the idle node bandwidth/storage (i.e., cloudlets) in the original P2P system to form an inherent cloudlet storage. Since P2P nodes are geographically distributed, highly dynamic and heterogeneous, Beehive adopts three key techniques to achieve high performance. First, by applying random linear network coding, multiple seeders can upload the same file simultaneously without complicated wide-area coordination. Second, a model is developed to set the coding parameters so that the cloudlet storage achieves guaranteed performance in file availability and data distribution efficiency. Finally, by performing task outsourcing, overloaded seeders quickly offload their tasks to idle peers, which effectively balances the load and utilizes the system resources. We implement Beehive with 29,000 lines of C++ codes and deploy it in a real P2P file-sharing system. Results show that Beehive improves the success ratio of pulling peer-side files from 38.7% (traditional online download) to 84.3% (users offline waiting for less than three days), and provides users with over 200 kB/s download speed. | XING YuanJian YANG Zhi CHEN Chi DAI YaFei | 2013 | Science China(Information Sciences)2013，56，7： | 0 |
| 15 | Water Molecule-Triggered Anisotropic Deformation of Carbon Nitride Nanoribbons Enabling Contactless Respiratory Inspection显示文摘The exploitation of the interaction between nanostructured matter and small molecules,such as H_(2)O at interfaces via dynamic hydrogen bonding,is essentially the key for smart,responsive nanodevices but remains challenging.Herein,the authors report that the carbon nitride nanoribbons(CNNRs)with an anisotropic intraplanar and interplanar molecular arrangement underwent a deformation by H_(2)O triggering.Both experiments of bulk samples and single nanoribbons disclosed that the reversible formation of a hydrogen-bonded H_(2)O adsorption layer was the source of the CNNRs deformation,reminiscent of the hydration-triggered twist of natural bean pods in seeding.Nonetheless,CNNRs had a more balanced H_(2)O affinity,enabling a superior response and recovery time.By coupling with carbon nanotubes,the authors also converted the deformation of CNNRs into more straightforward electrical readouts with record-fast response time.Further applied to capture fluctuations in humidity in real-time respiration,a higher detection sensitivity was obtained in a contactless mode,which compared favorably with the clinical breath-testing station.Given the carbon nitride family with various C/N ratios,surface properties,and topography,this finding that CNNRs are an outstanding H_(2)O transducer would significantly pave the way for the H_(2)O-triggered smart devices in broad prospective applications. | Yuye Zhang Yongxiu Song Yanfei Shen Kaiyang Chen Qing Zhou Yanqin Lv Hong Yang Ensheng Xu Songqin Liu Lei Liu Yuanjian Zhang | 2021 | CCS Chemistry2021，3，6： | 0 |
| 16 | Temporal dynamics of microglia-astrocyte interaction in neuroprotective glial scar formation after intracerebral hemorrhage显示文摘The role of glial scar after intracerebral hemorrhage(ICH)remains unclear.This study aimed to investigate whether microglia-astrocyte interaction affects glial scar formation and explore the specific function of glial scar.We used a pharmacologic approach to induce microglial depletion during different ICH stages and examine how ablating microglia affects astrocytic scar formation.Spatial transcriptomics(ST)analysis was performed to explore the potential ligand-receptor pair in the modulation of microglia-astrocyte interaction and to verify the functional changes of astrocytic scars at different periods.During the early stage,sustained microglial depletion induced disorganized astrocytic scar,enhanced neutrophil infiltration,and impaired tissue repair.ST analysis indicated that microglia-derived insulin like growth factor 1(IGF1)modulated astrocytic scar formation via mechanistic target of rapamycin(mTOR)signaling activation.Moreover,repopulating microglia(RM)more strongly activated mTOR signaling,facilitating a more protective scar formation.The combination of IGF1 and osteopontin(OPN)was necessary and sufficient for RM function,rather than IGF1 or OPN alone.At the chronic stage of ICH,the overall net effect of astrocytic scar changed from protective to destructive and delayed microglial depletion could partly reverse this.The vital insight gleaned from our data is that sustained microglial depletion may not be a reasonable treatment strategy for early-stage ICH.Inversely,early-stage IGF1/OPN treatment combined with late-stage PLX3397 treatment is a promising therapeutic strategy.This prompts us to consider the complex temporal dynamics and overall net effect of microglia and astrocytes,and develop elaborate treatment strategies at precise time points after ICH. | Jingwei Zheng Haijian Wu Xiaoyu Wang Guoqiang Zhang Jia'nan Lu Weilin Xu Shenbin Xu Yuanjian Fang Anke Zhang Anwen Shao Sheng Chen Zhen Zhao Jianmin Zhang Jun Yu | 2023 | Journal of Pharmaceutical Analysis2023，13，8： | 0 |
| 17 | Hierarchically porous carbon cages synthesized through in situ migration of templates显示文摘In order to optimize mass transportation and exchange,nature creates hierarchically porous networks which are composed of multi-level branches.Although bottom-up templating methods have succeeded in fabrication of these kinds of hierarchically porous networks,the templates have to be assembled/packed in advance,therefore,driving the fabrication process too complex.In this report,we presented that the hierarchically porous networks could be fabricated through migration of templates,which was similar to formation of rive rs.During thermal pyrolysis of Prussian blue cages,the in situly generated iron oxides nanoparticles diffused and aggrega ted together to grow larger,and eventually moved outside from the porous carbons.The moving routes of the iron oxides became hierarchical channels in the obtained carbon cages.By using the porous carbon cages as electrode for Na-ion battery,a pseudocapacitor-type ion storage was investigated. | Qing Fang Wei Zhang Xinghua Chen Yuanjian Zhang Ming Hu | 2020 | Chinese Chemical Letters2020，31，1： | 0 |
| 18 | Solution-based processing of carbon nitride composite for boosted photocatalytic activities显示文摘Graphite-phase polymeric carbon nitride(CN) was reported to be a promising material in photoelectrochemical solar energy conversion. However, its high recombination rate of photogenerated carriers limits its potential applications. In this article, a heterojunction of CN and sulfur-doped CN(CNS)was constructed through a solution-based processing way. Interestingly, it was observed that the photocatalytic hydrogen production of the as-prepared composite was 32.6 times higher than that of bulk carbon nitride and 2.3 times higher than that of the composites by conventional impregnating method.This study opens a new avenue to construct heterojunction of CN for large-scale industrial applications in environmental remediation. | Yile Chen Zhongshen Zhan Jianhai Wang Yanfei Shen Songqin Liu Yuanjian Zhang | 2018 | Chinese Chemical Letters2018，29，3： | 0 |
| 19 | Insights on“nitrate salt”in lithium anode for stabilized solid electrolyte interphase显示文摘A Li/KNO_(3) composite(LKNO),with KNO_(3) uniformly implanted in bulk metallic Li,is fabricated for battery anode via a facile mechanical kneading approach,which exhibits high Coulombic efficiency and prolonged cycle life.The mechanism behind the enhanced electrochemical performance of the“salt-in-metal”composite is investigated,where KNO_(3) in metallic Li composite electrode would be sustainably released into the electrolyte.The presence of NO_(3)-stabilizes the solid electrolyte interphase by producing functional Li_(3)N,LiNxOy,and Li_(2)O species.K^(+)from KNO_(3) also helps to form an electrostatic shield after its adsorption on the electrode protrusions,which suppresses the dendritic growth of metallic Li.With the above advantages,uniform Li plating with dense and planar structure is realized for the LKNO electrode.These findings reveal a deep understanding of the effect of the“saltin-metal”anode and provide new insights into the use of nitrate additives for high-energy-density Li metal batteries. | Lin Fu Xiancheng Wang Zihe Chen Yuanjian Li Eryang Mao Zhi Wei Seh Yongming Sun | 2022 | Carbon Energy2022，4，1： | 0 |
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