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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Multiphase Flow and Wear in the Cutting Head of Ultra-high Pressure Abrasive Water Jet显示文摘Abrasive water jet cutting technology is widely applied in the materials processing today and attracts great attention from scholars,but many phenomena concerned are not well understood,especially in the internal jet flow of the cutting head at the condition of ultra-high pressure.The multiphase flow in the cutting head is numerically simulated to study the abrasive motion mechanism and wear inside the cutting head at the pressure beyond 300 MPa.Visible predictions of the particles trajectories and wear rate in the cutting head are presented.The influences of the abrasive physical properties,size of the jewel orifice and the operating pressure on the trajectories are discussed.Based on the simulation,a wear experiment is carried out under the corresponding pressures.The simulation and experimental results show that the flow in the mixing chamber is composed of the jet core zone and the disturbance zone,both affect the particles trajectories.The mixing efficiency drops with the increase of the abrasive granularity.The abrasive density determines the response of particles to the effects of different flow zones,the abrasive with medium density gives the best general performance.Increasing the operating pressure or using the jewel with a smaller orifice improves the coherency of particles trajectories but increases the wear rate of the jewel holder at the same time.Walls of the jewel holder,the entrance of the mixing chamber and the convergence part of the mixing tube are subject to wear out.The computational and experimental results give a qualitative consistency which proves that this numerical method can provide a reliable and visible cognition of the flow characteristics of ultra-high pressure abrasive water jet.The investigation is benefit for improving the machining properties of water jet cutting systems and the optimization design of the cutting head. | YANG Minguan WANG Yuli KANG Can YU Feng | 2009 | Chinese Journal of Mechanical Engineering2009，22，5： | 8 |
| 3 | NOMA-Based UAV-Aided Networks for Emergency Communications显示文摘High spectrum efficiency(SE)requirement and massive connections are the main challenges for the fifth generation(5G)and beyond 5G(B5G)wireless networks,especially for the case when Internet of Things(IoT)devices are located in a disaster area.Non-orthogonal multiple access(NOMA)-based unmanned aerial vehicle(UAV)-aided network is emerging as a promising technique to overcome the above challenges.In this paper,an emergency communications framework of NOMA-based UAV-aided networks is established,where the disasters scenarios can be divided into three broad categories that have named emergency areas,wide areas and dense areas.First,a UAV-enabled uplink NOMA system is established to gather information from IoT devices in emergency areas.Then,a joint UAV deployment and resource allocation scheme for a multi-UAV enabled NOMA system is developed to extend the UAV coverage for IoT devices in wide areas.Furthermore,a UAV equipped with an antenna array has been considered to provide wireless service for multiple devices that are densely distributed in disaster areas.Simulation results are provided to validate the effectiveness of the above three schemes.Finally,potential research directions and challenges are also highlighted and discussed. | Wanmei Feng Jie Tang Nan Zhao Yuli Fu Xiuyin Zhang Kanapathippillai Cumanan Kai-Kit Wong | 2020 | China Communications2020，17，11： | 5 |
| 4 | Diversity of microbial plankton across the Three Gorges Dam of the Yangtze River,China显示文摘长江的三个峡水坝(TGD ) ,中国,在世界上是最大的灌溉和水力发电的工程工程之一。效果巨大人造象动物志和 macrophyte 上的 TGD 一样的工程是明显的,主要通过水动力学和流动模式的变化;然而,微生物怎么对如此的变化作出回应,是不太清楚的。这研究被瞄准在不同季节和地点在微生物引起的差异检验差别(在前面并且在 TGD 后面) 。另外,依附粒子、免费生活的社区之间的差别也被检验。在水列在后面并且在 TGD 前面的全部、潜在地活跃的微生物的社区结构与基于 DNA 、基于 RNA 的 16S rRNA 基因被分析在三个不同季节的种系发生的途径。16S rRNA 基因的克隆图书馆从提取 DNA 在扩大以后被准备并且为一些样品,在从提取 rRNA 准备 cDNA 以后。差别在不同季节并且在免费生活、依附粒子的社区之间在地点之间被观察。细菌并且 archaeal 社区比在冬季在夏天是更多样的,由于在夏天的更高滋养的层次和更温暖的温度比在冬季。依附粒子的微生物比免费生活的社区更多样,可能因为在粒子的更高滋养的层次和异构的 geochemical 微型环境。在细菌的社区结构的空间变化被观察,即,在 TGD 后面的水水库(在上游) 比在水坝前面招待了更多样的细菌的人口(下游) ,因为沉积和水从的多样的来源对水库在上游。这些结果在水坝建设影响的河生态系统为我们对环境变化的微生物引起的社区的回答的理解有重要含意。 | Shang Wang Raymond M. Dong Christina Z. Dong Liuqin Huang Hongchen Jiang Yuli Wei Liang Feng Deng Liu Guifang Yang Chuanlun Zhang Hailiang Dong | 2012 | Geoscience Frontiers2012，3，3： | 4 |
| 5 | Plasmacytoid dendritic cells promote acute kidney injury by producing interferon-α显示文摘Acute kidney injury(AKI)is a common clinical complication associated with high mortality in patients.Immune cells and cytokines have recently been described to play essential roles in AKI pathogenesis.Plasmacytoid dendritic cells(pDCs)are a unique DC subset that specializes in type Ⅰ interferon(IFN)production.Here,we showed that pDCs rapidly infiltrated the kidney in response to AKI and contributed to kidney damage by producing IFN-α.Deletion of pDCs using DTR^(BDCA2) transgenic(Tg)mice suppressed cisplatin-induced AKI,accompanied by marked reductions in proinflammatory cytokine production,immune cell infiltration and apoptosis in the kidney.In contrast,adoptive transfer of pDCs during AKI exacerbated kidney damage.We further identified IFN-α as the key factor that mediated the functions of pDCs during AKI,as IFN-α neutralization significantly attenuated kidney injury.Furthermore,IFN-α produced by pDCs directly induced the apoptosis of renal tubular epithelial cells(TECs)in vitro.In addition,our data demonstrated that apoptotic TECs induced the activation of pDCs,which was inhibited in the presence of an apoptosis inhibitor.Furthermore,similar deleterious effects of pDCs were observed in an ischemia reperfusion(IR)-induced AKI model.Clinically,increased expression of IFN-α in kidney biopsies was observed in kidney transplants with AKI.Taken together,the results of our study reveal that pDCs play a detrimental role in AKI via IFN-α. | Bo Deng Yuli Lin Yusheng Chen Shuai Ma Qian Cai Wenji Wang Bingji Li Tingyan Liu Peihui Zhou Rui He Feng Ding | 2021 | Cellular & Molecular Immunology2021，18，1： | 1 |
| 6 | Theoretical investigation on the energy absorption of ellipse-shaped self-locked tubes显示文摘Self-locked energy-absorbing systems have been proposed in previous studies to overcome the limitations associated with the round-tube systems because they can prevent the lateral splash of tubes from impact loadings without any constraints.In case of self-locked systems,the ellipse-shaped self-locked tube is considered to be an optimal design when compared with the ordinary circle-shaped self-locked tubes and other shaped self-locked tubes.In this study,we aim to theoretically analyze the ellipseshaped self-locked tubes.Further,a plastic hinge model is developed to predict the force-displacement relation of the tube,which is compared with the deformation process observed in the experiment and finite element method(FEM)simulation.Using this model,the effects of tuning the geometric parameters of the tube on the energy absorption performance,including the deformation efficiency,energy absorption capacity,and effective stroke ratio,are simulated and analyzed.Finally,a guideline is provided with respect to the design of the ellipse-shaped self-locked tube in engineering applications. | KuiJian Yang Chuan Qiao Feng Xiong Lei Zhang ZhangMing Wu YuLi Chen | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，9： | 1 |
| 7 | Cell relay-delivery improves targeting and therapeutic efficacy in tumors显示文摘Cell-mediated drug delivery system(CDDS)has shown great potential for cancer therapy.However,a single cell-mediated drug delivery mechanism has not generally been successful,particularly for systemic administration.To augment the antitumor therapy efficacy,herein,we propose a strategy of cell relay-delivery for the use of artificially damaging/aging erythrocytes to hitchhike on circulating monocytes/macrophages for intratumoral accumulation of anticancer drugs.This biomimetic relay-delivery strategy was derived from the manner in which circulating monocytes/macrophages in body specifically engulf damaged/senescent erythrocytes and actively transmigrate into the tumor bulk.The strategy elegantly combines the natural functions of both cells,which therefore provides a new perspective to challenge current obstacles in drug delivery.According to the strategy,we developed biotinylated erythrocyte-poly(lactic-co-glycolic acid)(PLGA)nanoparticle hybrid DDSs(bE-NPs)using avidin-biotin coupling.In such a system,biotinylated erythrocytes can mimic the natural property of damaged/senescent erythrocytes,while PLGA NPs are capable of encapsulating anticancer drugs and promoting sustained drug release.Anticancer drugs can effectively target tumor sites by two steps.First,by using biotinylated erythrocytes as the carrier,the drug-loaded PLGA NPs could be specifically phagocytized by monocytes/macrophages.Second,by taking advantage of the tumor-tropic property of monocytes/macrophages,the drug-loaded PLGA NPs could be efficiently transported into the tumor bulk.After encapsulating vincristine(VIN)as the model drug,bE-NPs exhibited the most favorable antitumor effects in vitro and in vivo by the cell relay-delivery effect.These results demonstrate that the cell relay-delivery provides a potential method for improving tumor treatment efficacy. | Ye Feng Qianqian Liu Yi Li Yang Han Meng Liang Hao Wang Qing Yao Yuli Wang Meiyan Yang Zhiping Li Wei Gong Yang Yang Chunsheng Gao | 2021 | Bioactive Materials2021，6，6： | 0 |
| 8 | Operational Methods for Ships in Waves From Perspectives of Structure Health and Maneuvering Convenience显示文摘 | ZHOU Feng ZHOU Junwei CHEN Yuli WANG Deling | 2017 | Journal of Shipping and Ocean Engineering2017，7，3： | 0 |
| 9 | Optimal alignment for maximizing the uniaxial modulus of 2D anisotropic random nanofiber networks显示文摘Nanofiber networks are effective structural forms to utilize the excellent nanoscale properties of nanofibers in macro scale.Properly tuning the anisotropic degree of fiber orientation distribution can maximize the macroscopic mechanical properties of random nanofiber networks in a specific direction.However,the reinforcing mechanism of the anisotropic orientation distribution to the elastic behavior has not been fully understood.In this paper,the effect of anisotropic orientation distribution of nanofibers on the elastic behavior of network is studied based on the modulus-density scaling relation and stiffness thresholds.The uniaxial modulus of network is determined by both the orientation angle of each fiber and interconnectivity of the random fiber network.With the increase of anisotropic degree,the contribution of fiber orientation angle to the network modulus of the preferential direction increases and gradually tends to a constant,while the interconnectivity of the networks decreases,which may reduce the loadability of network.Therefore,at a given network density,the uniaxial modulus along the preferential direction first increases to a maximum value and then decreases with the increase of the anisotropic degree.Furthermore,an expression to predict the optimal anisotropic degrees corresponding to the maximum uniaxial moduli at different network densities is established. | Baorang Cui Fei Pan Jingxiu Zhang Feng Zhang Yong Ma Yuli Chen | 2023 | International Journal of Smart and Nano Materials2023，14，1： | 0 |
| 10 | Molecular events in the jaw vascular unit:A traditional review of the mechanisms involved in inflammatory jaw bone diseases显示文摘Inflammatory jaw bone diseases are common in stomatology,including periodontitis,peri-implantitis,medication-related osteonecrosis of the jaw,radiation osteomyelitis of the jaw,age-related osteoporosis,and other specific infections.These diseases may lead to tooth loss and maxillofacial deformities,severely affecting patients'quality of life.Over the years,the reconstruction of jaw bone deficiency caused by inflammatory diseases has emerged as a medical and socioeconomic challenge.Therefore,exploring the pathogenesis of inflammatory diseases associated with jaw bones is crucial for improving prognosis and developing new targeted therapies.Accumulating evidence indicates that the integrated bone formation and dysfunction arise from complex interactions among a network of multiple cell types,including osteoblast-associated cells,immune cells,blood vessels,and lymphatic vessels.However,the role of these different cells in the inflammatory process and the'rules'with which they interact are still not fully understood.Although many investigations have focused on specific pathological processes and molecular events in inflammatory jaw diseases,few articles offer a perspective of integration.Here,we review the changes and mechanisms of various cell types in inflammatory jaw diseases,with the hope of providing insights to drive future research in this field. | Ruyu Wang Haoran Wang Junyu Mu Hua Yuan Yongchu Pang Yuli Wang Yifei Du Feng Han | 2023 | The Journal of Biomedical Research2023，37，5： | 0 |
| 11 | Partial Topology Identification of Stochastic Multi-Weighted Complex Networks Based on Graph-Theoretic Method and Adaptive Synchronization显示文摘This article aims to identify the partial topological structures of delayed complex network.Based on the drive-response concept,a more universal model,which includes nonlinear couplings,stochastic perturbations and multi-weights,is considered into drive-response networks.Different from previous methods,we obtain identification criteria by combining graph-theoretic method and adaptive synchronization.After that,the partial topological structures of stochastic multi-weighted complex networks with or without time delays can be identified successfully.Moreover,response network can reach synchronization with drive network.Ultimately,the effectiveness of the proposed theoretical results is validated through numerical simulations. | Huiling Chen Chunmei Zhang Yuli Feng Qin Xu | 2023 | Advances in Applied Mathematics and Mechanics2023，15，6： | 0 |
| 12 | 镍氢催化的烯烃与硝基芳烃的远程氢胺化反应显示文摘文章简介现代有机合成追求更高效的合成策略,比如从简单易得的原料出发的惰性C-H键的直接官能团来构建复杂的有机分子。在烷基碳链上远程的惰性C-H位点挑战性地直接引入胺基. | 肖继超 Yuli He Feng Ye 朱少林 | 2019 | 科学新闻2019，0，2： | 0 |
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