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| 1 | A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of BT-H1显示文摘 | Huiming Sheng | 2008 | Cell Research2008，18，8： | 55 |
| 2 | A High-Density SNP Genotyping Array for Rice Biology and Molecular Breeding显示文摘一个高密度的单个核苷酸多型性(SNP ) 数组为遗传学者和分子的 breeders.With 是极其重要的 genomic 的巨大的数量的累积重新定序为精确 SNP 察觉的数据和可得到的技术,设计高密度、高质量的米饭 SNP 数组是可能的。这里,我们报导一个高密度的 riceSNP 数组和它的实用程序的开发。SNP 探针被屏蔽超过 10 设计从变化和一个数组说出 RiceSNP50 的 801 米饭的 re-sequencingdata 提取的 000 000 SNP loci 在 Illumina Infinium 站台上被生产。数组 contained51 478 个均匀地分布式的标记,其 68% 个在遗传因子的区域以内。有 parent/F1 relationshipswere 的几百米饭植物过去常为精确 SNP 打电话产生一个高质量的簇文件。应用程序测试证明这穿有的 highgenotyping 精确性,并且能被用于不同目的。例如,有好分辨率的精英米饭变化 wasclustered 的一个核心集合。染色体宽的协会研究(GWAS ) 分析正确地识别了描绘的 QTL.Further,这个数组成功地为变化确认和特点基因渗入被使用。作为一个精确 high-throughputgenotyping 工具, RiceSNP50 将在两功能的 genomics 学习和分子的 breeding.Key 词起一个重要作用: | Haodong Chen Weibo Xie Hang He Huihui Yu Wei Chen Jing Li Renbo Yu Yue Yao Wenhui Zhang Yuqing He Xiaoyan Tang Fasong Zhou Xing Wang Deng Qifa Zhang | 2014 | Molecular Plant2014，7，3： | 38 |
| 3 | Mechanism of acupuncture regulating visceral sensation and mobility显示文摘Chinese ancient medical scientists have long focused on the internal and external contacts between acupoints on the surface of the body and the viscera.The Miraculous Pivot(it is one of the earliest medical classics in China)stated,“Twelve regular channels belong to the zang-fu organs internally,and connect to the extremities and joints externally.”Traditional Chinese medicine considers acupoints as defined areas where the Qi of viscera and meridians are transfused.These include the reaction points of visceral diseases on the body surface as well as the acupuncture trigger points that promote the flow of Qi and blood,and regulate visceral function.Chinese ancient medical scientists classified the specificity of the main acupoints in the body based on the meridian doctrine,which has been instructing clinical application for about 2000 years.Laws on the domino effect of acupoints have mainly focused on conclusions to clinical experiences.Indications of some acupoints exceed the practical paradigm since the excessive extension occurred during theory derivation.The current research direction on acupuncture focuses on three aspects:the effectiveness of acupuncture and moxibustion;the relevances and associations between meridians and viscera;and the physical and chemical properties and relevant physical basis of acupoints.The relevance between meridians and viscera is the central theory in the meridian doctrine,and acupoints are regarded as an important link in the relationship between meridians and viscera.Specific relationships between acupoints and target organs exist.Stimulating different acupoints on the body surface can help deal with different diseases,especially visceral diseases.In addition,acupoints have a dual function of reflecting and treating visceral diseases.There is no systemic research available on acupoint specificity,despite current knowledge and clinical experiences,which results in a weak foundation for acupuncture theory.This study focuses on the relevance and associations between meridians and viscera.A summary of the mechanisms of acupuncture regulating visceral sensation and mobility and the specific relationships between acupoints and their target organs are presented in this review. | Peijing Rong Bing Zhu Yuqing Li Xinyan Gao Hui Ben Yanhua Li Liang Li Wei He Rupeng Liu Lingling Yu | 2011 | Frontiers of Medicine2011，5，2： | 8 |
| 4 | Purification and characterization of a novel and unique ginsenoside Rgrhydrolyzing β-D-Glucosidase from Penicillium sclerotiorum显示文摘 | Ying Wei Wenqian Zhao Qi Zhang Yuqing Zhao Yixuan Zhang | 2011 | Acta Biochimica et Biophysica Sinica2011，43，3： | 6 |
| 5 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 6 | A PREDICTIVE APPROACH TO THE IN-PLANE MECHANICAL PROPERTIES OF STITCHED COMPOSITE LAMINATES显示文摘这贡献试图为在里面飞机橡皮性质的改变建模在,并且预言在里面飞机把压成薄片由缝引起了有效张力的力量缝合成把压成薄片。在里面飞机纤维的失真被认为是影响在里面飞机的主要原因机械性质。一个纤维失真模型被建议由于缝描绘纤维错误排列和纤维内容集中。未失真的区域,纤维失真区域,充满树脂的衣袋和通过厚度加强节被考虑。纤维错误排列和由于缝满意的不同类的纤维被介绍二个参数,失真宽度和最大的错误排列提出了。厚度强调集中在,这被发现了缝把压成薄片被二个并发的因素,针洞和不同类的纤维内容影响。而在缝导致的本地区域的更高的纤维内容制止本地变丑,针洞引起压力集中合成。模型被用来预言张力的力量[0/45/0/-45/90/45/0/-45 ]_(2s ) T300/QY9512 合成把压成薄片与不同缝的配置由 Kevlar 29 纱缝了,与试验性的数据显示出一个可接受的协议。 | Zhang Junqian Wei Yuqing | 2007 | Acta Mechanica Solida Sinica2007，20，2： | 5 |
| 7 | Expert consensus on early childhood caries management显示文摘Early childhood caries(ECC)is a significant chronic disease of childhood and a rising public health burden worldwide.ECC may cause a higher risk of new caries lesions in both primary and permanent dentition,affecting lifelong oral health.The occurrence of ECC has been closely related to the core microbiome change in the oral cavity,which may be influenced by diet habits,oral health management,fluoride use,and dental manipulations.So,it is essential to improve parental oral health and awareness of health care,to establish a dental home at the early stage of childhood,and make an individualized caries management plan.Dental interventions according to the minimally invasive concept should be carried out to treat dental caries.This expert consensus mainly discusses the etiology of ECC,caries-risk assessment of children,prevention and treatment plan of ECC,aiming to achieve lifelong oral health. | Jing Zou Qin Du Lihong Ge Jun Wang Xiaojing Wang Yuqing Li Guangtai Song Wei Zhao Xu Chen Beizhan Jiang Yufeng Mei Yang Huang Shuli Deng Hongmei Zhang Yanhong Li Xuedong Zhou | 2022 | International Journal of Oral Science2022，14，3： | 5 |
| 8 | Dynamic analysis of traction motor in a locomotive considering surface waviness on races of a motor bearing显示文摘The traction motor is the power source of the locomotive.If the surface waviness occurs on the races of the motor bearing,it will cause abnormal vibration and noise,accelerate fatigue and wear,and seriously affect the stability and safety of the traction power transmission.In this paper,an excitation model coupling the time-varying displacement and contact stiffness excitations is adopted to investigate the effect of the surface waviness of the motor bearing on the traction motor under the excitation from the locomotive-track coupled system.The detailed mechanical power transmission path and the internal/external excitations(e.g.,wheel–rail interaction,gear mesh,and internal interactions of the rolling bearing)of the locomotive are comprehensively considered to provide accurate dynamic loads for the traction motor.Effects of the wavenumber and amplitude of the surface waviness on the traction motor and its neighbor components of the locomotive are investigated.The results indicate that controlling the amplitude of the waviness and avoiding the wavenumber being an integer multiple of the number of the rollers are helpful for reducing the abnormal vibration and noise of the traction motor. | Yuqing Liu Zaigang Chen Wei Li Kaiyun Wang | 2021 | Railway Engineering Science2021，29，4： | 5 |
| 9 | Friction of metal-matrix self-lubricating composites: Relationships among lubricant content, lubricating film coverage, and friction coefficient显示文摘Metal-matrix self-lubricating composites can exhibit excellent tribological properties owing to the release of solid lubricant from the matrix and the formation of a lubricating film on the tribosurface.The coverage of the lubricating film on a worn surface significantly influences the sliding process.However,it is difficult to quantify the film coverage owing to the thin and discontinuous character of the lubricating film and the high roughness of the worn surface.A quantitative characterization of the lubricating film coverage based on X-ray photoelectron spectroscopy(XPS)analysis was developed in this study.The friction tests of Cu-MoS2 composites with a MoS2 content of 0-40 vol%were conducted,and the worn surfaces of the composites were observed and analyzed.Further,the influence of the MoS2 volume content on the coverage of the lubricating film on the worn surface was investigated.The relationships among the volume fraction of the lubricant,coverage of the lubricating film,and the friction coefficient were established.The friction model for the metal matrix self-lubricating composites was developed and verified to facilitate the composition design and friction coefficient prediction of self-lubricating composites. | Jinkun XIAO Yuqing WU Wei ZHANG Juan CHEN Chao ZHANG | 2020 | Friction2020，8，3： | 5 |
| 10 | Inducing Flow Velocities to Manage Fish Reproduction in Regulated Rivers显示文摘Conservation of endangered or economic fish and control of invasive fish is a great challenge of hydraulic engineering worldwide.Flow velocity has been recognized to affect the spawning of fishes delivering drifting eggs in rivers.However,solid scientific supports and associated mechanisms to establish quantitative relations between flow velocity and fish reproduction,taking into account spawning,fertilizing,hatching,as well as surviving,are lacking.In this paper,we quantified the relationship between flow velocity and reproduction of Chinese carps through both lab and field experiments.The results showed that a minimum velocity was required to trigger Hypophthalmichthys molitrix(H.molitrix)releasing eggs,and a velocity range was preferred to sustain spawning activity.However,the embryo incubation and larvae development of H.molitrix were found to be inhibited with the increase in flow velocity.Considering the requirements of spawning and hatching,as well as larvae surviving,an optimized flow velocity processes was identified for the reproduction of H.molitrix in rivers.These findings were of great significance to the adaptive operation of reservoirs to create reasonable and precise ecological flows for managing fish reproduction,as shown by the promising results in the engineering application to the Three Gorges Reservoir. | Qiuwen Chen Jianyun Zhang Yuchen Chen Kangle Mo Jun Wang Lei Tang Yuqing Lin Lei Chen Yong Gao Wei Jiang Yuxin Zhang | 2021 | Engineering2021，7，2： | 4 |
| 11 | Photoinduced large polaron transport and dynamics in organic-inorganic hybrid lead halide perovskite with terahertz probes显示文摘Organic-inorganic hybrid metal halide perovskites(MHPs)have attracted tremendous attention for optoelectronic applications.The long photocarrier lifetime and moderate carrier mobility have been proposed as results of the large polaron formation in MHPs.However,it is challenging to measure the effective mass and carrier scattering parameters of the photogenerated large polarons in the ultrafast carrier recombination dynamics.Here,we show,in a one-step spectroscopic method,that the optical-pump and terahertz-electromagnetic probe(OPTP)technique allows us to access the nature of interplay of photoexcited unbound charge carriers and optical phonons in polycrystalline CH_(3)NH_(3)PbI_(3)(MAPbI_(3))of about 10μm grain size.Firstly,we demonstrate a direct spectral evidence of the large polarons in polycrystalline MAPbI_(3).Using the Drude-Smith-Lorentz model along with the Frӧhlich-type electron-phonon(e-ph)coupling,we determine the effective mass and scattering parameters of photogenerated polaronic carriers.We discover that the resulting moderate polaronic carrier mobility is mainly influenced by the enhanced carrier scattering,rather than the polaron mass enhancement.While,the formation of large polarons in MAPbI_(3)polycrystalline grains results in a long charge carrier lifetime at room temperature.Our results provide crucial information about the photo-physics of MAPbI3 and are indispensable for optoelectronic device development with better performance. | Zuanming Jin Yan Peng Yuqing Fang Zhijiang Ye Zhiyuan Fan Zhilin Liu Xichang Bao Heng Gao Wei Ren Jing Wu Guohong Ma Qianli Chen Chao Zhang Alexey VBalakin Alexander PShkurinov Yiming Zhu Songlin Zhuang | 2022 | Light(Science & Applications)2022，11，8： | 4 |
| 12 | Accurate assessment of antibiotic susceptibility and screening resistant strains of a bacterial population by linear gradient plate显示文摘The dynamics of a bacterial population exposed to theminimum inhibitory concentration (MIC) of an antibiotic is an important issue in pharmacological research.Therefore,a novel antibiotic susceptibility test is urgently needed that can both precisely determine the MIC and accurately select antibiotic-resistant strains from clinical bacterial populations.For this purpose,we developed a method based on Fick's laws of diffusion using agar plates containing a linear gradient of antibiotic.The gradient plate contained two layers.The bottom layer consisted of 15 mL agar containing the appropriate concentration of enrofloxacin and allowed to harden in the form of a wedge with the plate slanted such that the entire bottom was just covered.The upper layer consisted of 15 mL plain nutrient agar added with the plate held in the horizontal position.After allowing vertical diffusion of the drug from the bottom agar layer for 12 h,the enrofloxacin concentration was diluted in proportion to the ratio of the agar layer thicknesses.The uniform linear concentration gradient was verified by measuring the enrofloxacin concentration on the agar surface.When heavy bacterial suspensions were spread on the agar surface and incubated for more than 12 h,only resistant cells were able to form colonies beyond the boundary of confluent growth of susceptible cells.In this way,the true MIC of enrofloxacin was determined.The MICs obtained using this linear gradient plate were consistent with those obtained using conventional antibiotic susceptibility tests.Discrete colonies were then spread onto a gradient plate with higher antibiotic concentrations;the boundary line increased significantly,and gene mutations conferring resistance were identified.This new method enables the rapid identification of resistant strains in the bacterial population.Use of the linear gradient plate can easily identify the precise MIC and reveal the dynamic differentiation of bacteria near the MIC.This method allows the study of genetic and physiological characteristics of individual strains,and may be useful for early warning of antibiotic resistance that may occur after use of certain antimicrobial agents,and guide clinical treatment. | LIU YuQing LI JingRan DU JiaFa HU Ming BAI Hua QI Jing GAO Chao WEI TianTian SU Hong JIN JianLing GAO PeiJi | 2011 | Science China(Life Sciences)2011，54，10： | 4 |
| 13 | Is Process as Important as Outcome? Empirical Evidence from the Chinese Context显示文摘尽管在薪水水平和薪水满足之间的关系在薪水满足的文学作为最柔韧的关系之一被验证了,学者们还没关于它的内在的机制达成了一个协议。调查在绝对薪水水平和薪水之间的连接的现在的纸目的由根据公平作为调停人介绍分发、程序的公平感觉铺平满足启发式的观点。从组织的各种各样的类型的 298 个雇员的一件样品完成了调查,并且一系列模型与相比如果假设理论模型适合我们的数据,评估。我们也构造了改正偏爱自举测试假设调停效果的信心间隔。建议理论模型被支持,并且未来研究方向被讨论。 | Lel Wang ShiYong Xu Wei Huang Yuqing Zhang | 2014 | Frontiers of Business Research in China2014，8，4： | 4 |
| 14 | Corrosion resistance and anti-soiling performance of micro-arc oxidation/graphene oxide/stearic acid superhydrophobic composite coating on magnesium alloys显示文摘Magnesium(Mg)alloys,the lightest metal construction material used in industry,play a vital role in future development.However,the poor corrosion resistance of Mg alloys in corrosion environments largely limits their potential wide applications.Therefore,a micro-arc oxidation/graphene oxide/stearic acid(MAO/GO/SA)superhydrophobic composite coating with superior corrosion resistance was fabricated on a Mg alloy AZ91D through micro-arc oxidation(MAO)technology,electrodeposition technique,and self-assembly technology.The composition and microstructure of the coating were characterized by scanning electron microscopy,X-ray diffraction,energy dispersive spectroscopy,and Raman spectroscopy.The effective protection of the MAO/GO/SA composite coating applied to a substrate was evaluated using potentiodynamic polarization,electrochemical impedance spectroscopy tests,and salt spray tests.The results showed that the MAO/GO/SA composite coating with a petal spherical structure had the best superhydrophobicity,and it attained a contact angle of 159.53°±2°.The MAO/GO/SA composite coating exhibited high resistance to corrosion,according to electrochemical and salt spray tests. | Dong Wang Chen Ma Jinyu Liu Weidong Li Wei Shang Ning Peng Yuqing Wen | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，6： | 3 |
| 15 | Preliminary Theoretical Studies on the Combination of Halogen Ions with Crown Tetraalanylpeptide显示文摘 | Hongtao Song Guoping Liu Yuqing Yang Hui Gao Hongyuan Wei Shunzhong Luo | 2010 | Journal of Chemistry and Chemical Engineering2010，4，4： | 3 |
| 16 | ZIF-8-based micro-arc oxidation composite coatings enhanced the corrosion resistance and superhydrophobicity of a Mg alloy显示文摘Mg alloys are considered the most promising engineering materials because of their unique properties.However,the uncontrolled corrosion rate of these alloys limits their applications.Therefore,in this study,a micro-arc oxidation layer was used as a transition layer to“directly”grow a zinc-based metal-organic framework(MOF)composite coating on the surface of a Mg alloy(AZ91D).Herein,the two zeolitic imidazolate framework(ZIF-8)coatings with different morphologies were separately prepared by homologous metal oxide induction and a one-step in-situ growth method.The superhydrophobic composite coating showed strong hydrophobicity and self-cleaning properties,which could prevent the penetration of water and corrosive ions(Cl^(−))into the surface of AZ91D.Electrochemical tests demonstrated that the super-hydrophobic composite coatings greatly enhanced the corrosion resistance of AZ91D,and the corrosion current density decreased from 10^(−5)to 10^(−9)A/cm^(2).These results indicate that the ZIF-8 coatings are beneficial for improving the hydrophobicity and enhancing the corrosion resistance of Mg alloys.Therefore,MOF composite coatings provide a new strategy that can be used to prepare multifunctional anticorrosion coatings on metal substrates. | Shiquan Jiang Zhiyuan Zhang Dong Wang Yuqing Wen Ning Peng Wei Shang | 2023 | Journal of Magnesium and Alloys2023，11，4： | 3 |
| 17 | Preparation and primary biological evaluation of novel nitrido-^(188)Re complexes/lipiodol显示文摘Two new nitrido-188Re complexes were prepared by a modified method in high yield. These complexes were stable in vitro. The biodistribution in normal mice showed that these nitrido-188Re complexes could accumulate in liver and dissipate quickly from almost all organs. TAE was performed with the use of lipiodol solutions of two complexes to rabbit VX2 liver tumor models. SPECT images showed that the two lipiodol solutions could remain in tumor for about 9h (188ReN-NEPTDD/lipiodol) and 12h (188ReN-NEMMPTDD/lipiodol),respectively. | WANG Guanquan WEI Hongyuan LUO Shunzhong HE Jiaheng YANG Yuqing WANG Wenjin XIONG Xiaoling | 2008 | Nuclear Science and Techniques2008，19，4： | 3 |
| 18 | Recent understanding of solid-liquid friction in ionic liquids显示文摘Ionic liquids(ILs)-solid interfacial phenomenon is undoubtedly one of the topic issues in energy related fields,especially bringing great challenges in the development of chemical engineering.Solid-ILs friction under microscale shows outstanding properties such as widely studied electro-controllability by surface potential or electric field,and promising performance of superlubricity.Vast applications,such as boundary lubrication and supercapacitors,have been benefiting from these studies.In this review,we summarized the recent advances of the measurements of solid-ILs friction,and focused on the microscale and fascinating findings.A brief tutorial for this topic,containing both experimental and theoretical methods,was also provided.It was anticipated that this review would help researchers grasp the emerging field and stimulate the advance of new ideas and methods in ILs on solids. | Yuqing He Han Li Cangyu Qu Wei Cao Ming Ma | 2021 | Green Chemical Engineering2021，2，2： | 2 |
| 19 | 3UVH2 and SUVH9 Couple Two Essential Steps For Transcriptional Gene Silencing in Arabidopsis显示文摘在 Arabidopsis,一条指导 RNA 的 DNA methylation 小径(RdDM ) 为 DNA methylation 的 de novo 建立负责并且贡献 transcriptional 基因 silencing。最近, microrchidia (MORC ) 类型 ATPases 被显示在由调整高顺序的染色质建筑学的形成强制基因和 transposons 的一个子集的 transcriptional 基因 silencing 起必要作用。然而, MORC 蛋白质怎么与 RdDM 小径部件合作调整基因表示,仍然保持大部分不清楚。在这研究, SUVH9 和 MORC6 从一屏蔽 idm1 的 suppressors 被识别,它是在活跃 DNA demethylation 的一个变异的有缺陷者。没有提高 DNA methylation 层次, SUVH9 和 MORC6 为二记者基因和一些内长的基因的 silencing 被要求。SUVH9,苏(增值商) 3-9 相当或相同的事物之一在 RdDM 包含了,直接与 MORC6 和它的二个靠近的相当或相同的事物交往, MORC1 和 MORC2。类似于 MORC6, SUVH9 和它的相当或相同的事物 SUVH2 在 SDC 和 Solo-LTR loci 为 heterochromatin 冷凝作用和 3D 染色质建筑学的形成被要求。我们建议 SUVH2 和 SUVH9 绑在 methylated DNA 并且与 MORC 蛋白质联合便于改变染色质的建筑群的招募到目标 loci。 | Yuqing Jing Han Sun Wei Yuan Yue Wang Qi Li Yannan Liu Yan Li Weiqiang Qian | 2016 | Molecular Plant2016，9，8： | 2 |
| 20 | Improvement of cardiac function by hepatocyte growth factor via intracoronary transfection in the swine myocardial infarction model显示文摘Objective:To study the amelioration effect of Adenovirus5-mediated human hepatocyte growth factor(Ad5-HGF)on postinfarction heart failure in the swine myocardial infarction model.Methods:Twelve SuZhong young swine were randomly divided into 2 groups with 6 swine in each group:Ad5-HGF-treated group and null-Ad5 group.Four weeks after ligation at left anterior descending coronary artery in swine hearts,Ad5-HGF was transferred to the swine myocardium.Simultaneously,Gated myocardial perfusion imaging was performed to evaluate cardiac perfusion and heart function.After three weeks,Gated myocardial perfusion imaging was performed again,then the hearts were harvested and sectioned to examine the expression of HGF through ELISA.Results:High expression of human HGF was observed in the myocardium of Ad5-HGF-treated group.From 4 weeks to 7 weeks after operation,Left ventricular ejection fraction was increased in Ad5-HGF-treated group.The improvement in LVEF was greater in Ad5-HGF-treated group than that in null-Ad5 group at 7 weeks after operation.Cardiac perfusion was significantly improved in the Ad5-HGF-treated group.Conclusion:High expression of human HGF was observed in the myocardium through intracoronary transfection,which suggests that HGF can ameliorate heart function in swine with postinfarction heart failure. | Wei Wang Zhijian Yang Dongchao Ma Shunlin Xu Yourong Zhang Yuqing Zhang Liansheng Wang Bo Chen Kejiang Cao Wenzhu Ma | 2006 | Journal of Nanjing Medical University2006，20，4： | 2 |
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