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3篇 您的检索式:作者名="Yuting Lian"
    题名 作者 年代 出处 被引量
1Fast-chargingand dendrite-free lithiummetal anodeeenabledby partial lithiation ofgraphene aerogel显示文摘The development of deeply cyclable lithium metal batteries with fast-charging capability offers a promising solution to relieve the“range anxiety”in driving electric vehicles.Conventional lithium metal anodes suffered from low operating current densities and shallow charge/discharge depths,owing to the intrinsic dendrite growth governed by Sand’s law.Herein,we come up with a novel design of heavy-duty lithium metal anode fabricated by partially infusing the three-dimensional(3D)porous graphene aerogel with molten Li.Both electroanalytical measurements and simulations show that the unique electrode architecture brings notable advantages in mediating smooth Li plating/stripping,including reduced local current density,inhibited dendrite growth,buffered volume fluctuation,as well as more efficient Li utilization.Consequently,a remarkable cycling performance in symmetric cells for over 400 cycles(800 h)with an ultrahigh cycling capacity of 15 mAh·cm^(−2) at 15 mA·cm^(−2) is achieved,which,to our best knowledge,has been never seen in literature.LiFePO4 full cells demonstrate a superb rate capability up to 10 C and a prolonged cycling of 1,600 cycles at 2 C with the per-cycle capacity decay of only 0.023%.This study paves the way for the ultimate deployment of lithium metal batteries in real-world applications that require fast charging and deep cycling.Yong Ma Yuting Gu Ying He Le Wei Yuebin Lian Weiyi Pan Xinjian Li Yanhui Su Yang Peng Zhao Deng Zhongfan Liu 2022Nano Research2022,15,11:1
2Milk-derived exosomes as a promising vehicle for oral delivery of hydrophilic biomacromolecule drugs显示文摘Exosomes,as promising vehicles,have been widely used in the research of oral drug delivery,but the generally low drug loading efficiency of exosomes seriously limits its application and transformation.In this study,we systematically investigated the effects of drug loading methods and physicochemical properties(lipophilicity and molecular weight)on drug loading efficiency of milk-derived exosomes to explore the most appropriate loading conditions.Our finding revealed that the drug loading efficiency of exosomes was closely related to the drug loading method,drug lipophilicity,drug molecular weight and exosome/drug proportions.Of note,we demonstrated the universality that hydrophilic biomacromolecule drugs were the most appropriate loading drugs for milk-derived exosomes,which was attributed to the efficient loading capacity and sustained release behavior.Furthermore,milk-derived exosomes could significantly improve the transepithelial transport and oral bioavailability of model hydrophilic biomacromolecule drugs(octreotide,exendin-4 and salmon calcitonin).Collectively,our results suggested that the encapsulation of hydrophilic biomacromolecule drugs might be the most promising direction for milk exosomes as oral drug delivery vehicles.Yuting Li Liyun Xing Lingling Wang Xi Liu Licheng Wu Mingjie Ni Zhou Zhou Lian Li Xiuxiu Liu Yuan Huang 2023Asian Journal of Pharmaceutical Sciences2023,18,2:1
3A Secure Supply of Antiretroviral Medicines for People Living with HIV During the COVID-19 Pandemic—China’s Experience显示文摘The occurrence of acute infectious diseases or severe natural disasters has a negative impact on the medical system(1).A survey of 105 countries by the World Health Organization(WHO)from March to June 2020 found that health services were disrupted in 90%of countries due to the coronavirus disease 2019(COVID-19)pandemic,with low-and middle-income countries being the most affected.Human immunodeficiency virus(HIV)treatment continuity and healthcare service delivery were also affected by the COVID-19 pandemic(2–3).Yan Zhao Mengjie Han Yuting Lian Qiang Wang Xiumin Gan Lan Yu Chuntao Ma 2022China CDC weekly2022,4,38:0
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