|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Determination of hexabromocyclododecanes in sediments from the Haihe River in China by an optimized HPLC–MS–MS method显示文摘Hexabromocyclododecanes(HBCDs),a new type of persistent organic pollutants widely used as brominated flame retardants,have attracted wide attention due to their increasing level and toxicity. A method based on high-performance liquid chromatography mass spectrometry(HPLC–MS–MS)in electrospray ionization mode has been developed by optimization of various parameters,which effectively improved the separation degree and responsive intensity of α-,β-and γ-HBCD isomers. The concentrations and distribution profiles of three HBCD isomers were investigated in sediments from the Haihe River in China.It was observed that the concentrations of HBCDs varied in the range of 0.4–58.82 ng/g,showing a decreasing trend along the flow direction,possibly due to attenuation and biodegradation along the flow direction of the Haihe River. The distribution profile of α-,β-,γ-HBCD was 7.91%–88.6%,0–91.47%,and 0.62%–42.83%,respectively. Interestingly,α-HBCD dominated in most sample sites. This was different from the distribution profile in commercial industrial products,which might be attributed to the inter-transformation and different degradation rates of the three HBCD isomers. The potential ecological risk of HBCDs in sediment was characterized under the two-tiered procedure of the European Medicines Evaluation Agency for environmental risk assessment. Although the HBCDs in the selected section of the Haihe River presented 'no risk' in the sediment compartment,its risk in sediment cannot be neglected since sediment is one of the important sinks and reservoirs of pollutants. | Yanhui Zhao Qianqian Li Xue Miao Xinchen Huang Binke Li Guijin Su Minghui Zheng | 2017 | Journal of Environmental Sciences2017，29，5： | 5 |
| 2 | Genome-wide comprehensive analysis of transcriptomes and small RNAs offers insights into the molecular mechanism of alkaline stress tolerance in a citrus rootstock显示文摘Alkaline stress has serious-negative effects on citrus production.Ziyang xiangcheng(Citrus junos Sieb.ex Tanaka)(Cj)is a rootstock that is tolerant to alkaline stress and iron deficiency.Trifoliate orange(Poncirus trifoliata(L.)Raf.)(Pt),the most widely used rootstock in China,is sensitive to alkaline stress.To investigate the molecular mechanism underlying the tolerance of Cj to alkaline stress,next-generation sequencing was employed to profile the root transcriptomes and small RNAs of Cj and Pt seedlings that were cultured in nutrient solutions along a three pH gradient.This two-level regulation data set provides a system-level view of molecular events with a precise resolution.The data suggest that the auxin pathway may play a central role in the inhibitory effect of alkaline stress on root growth and that the regulation of auxin homeostasis under alkaline stress is important for the adaptation of citrus to alkaline stress.Moreover,the jasmonate(JA)pathway exhibits the opposite response to alkaline stress in Cj and Pt and may contribute to the differences in the alkaline stress tolerance and iron acquisition between Cj and Pt.The dataset provides a wealth of genomic resources and new clues to further study the mechanisms underlying alkaline stress resistance in Cj. | Juxun Wu Junying Cao Mei Su Guizhi Feng Yanhui Xu Hualin Yi | 2019 | Horticulture Research2019，6，1： | 4 |
| 3 | Cloning and analysis of a cDNA encoding acetohydroxy acid isomeroreductase from G2 pea显示文摘Using cDNA representational difference analysis (cDNA RDA) method, we have successfully isolated a gene fragment whose expression was specifically induced by external GAa application. Screening a G2 pea cDNA library using this fragment as a probe, we obtained a 2036 bp full-length cDNA. It contains a 1746 bp open reading frame and encodes a protein of 581 amino acids with a theoretical molecular weight of 64 ku. It shares high-level sequenceidentity with AAIR genes from other plant species. This cDNA was cloned into expression vector and recombinant E. coli DH5α cells with remarkable AAIR enzyme activity were obtained. | XU Huasong XU Yunjian GU Xuesong HU Tingzhang SU Yanhui ZHU Yuxian | 2001 | Chinese Science Bulletin2001，46，21： | 4 |
| 4 | Overexpression of miR-101 suppresses collagen synthesis by targeting EZH2 in hypertrophic scar fibroblasts显示文摘Background:MicroRNA-101(miR-101)is a tumor suppressor microRNA(miRNA)and its loss is associated with the occurrence and progression of various diseases.However,the biological function and target of miR-101 in the pathogenesis of hypertrophic scars(HS)remains unknown.Methods:We harvested HS and paired normal skin(NS)tissue samples from patients and cultured their fibroblasts(HSF and NSF,respectively).We used quantitative reverse transcriptase polymerase chain reaction(qRT-PCR),fluorescence in situ hybridization(FISH),enzyme-linked immunosorbent assays(ELISA)and Western blot analyses to measure mRNA levels and protein expression of miR-101,enhancer of zeste homolog 2(EZH2),collagen 1 and 3(Col1 and Col3)andα-smooth muscle actin(α-SMA)in different in vitro conditions.We also used RNA sequencing to evaluate the relevant signaling pathways and bioinformatics analysis and dual-luciferase reporter assays to predict miR-101 targets.We utilized a bleomycin-induced fibrosis mouse model in which we injected miR-101 mimics to evaluate collagen deposition in vivo.Results:We found low expression of miR-101 in HS and HSF compared to NS and NSF.Overexpressing miR-101 decreased Col1,Col3 andα-SMA expression in HSF.We detected high expression of EZH2 in HS and HSF.Knockdown of EZH2 decreased Col1,Col3 andα-SMA in HSF.Mechanistically,miR-101 targeted the 3-untranslated region(3UTR)of EZH2,as indicated by the decreased expression of EZH2.Overexpressing EZH2 rescued miR-101-induced collagen repression.MiR-101 mimics effectively suppressed collagen deposition in the bleomycin-induced fibrosis mouse model.Conclusions:Our data reveal that miR-101 targets EZH2 in HS collagen production,providing new insight into the pathological mechanisms underlying HS formation. | Jie Li Yan Li Yunchuan Wang Xiang He Jing Wang Weixia Cai Yanhui Jia Dan Xiao Jian Zhang Ming Zhao Kuo Shen Zichao Li Wenbin Jia Kejia Wang Yue Zhang Linlin Su Huayu Zhu Dahai Hu | 2021 | Burns & Trauma2021，9，1： | 3 |
| 5 | BJ-TSA-9 , a Novel Human Tumor-Specific Gene, Has Potential as a Biomarker of Lung Cancer显示文摘 | Yunyan Li Xueyuan Dong Yanhui Yin Yanrong Su Qingwen Xu Yuxia Zhang Xuewen Pang Yu Zhang Weifeng Chen | 2005 | Neoplasia2005，，： | 1 |
| 6 | Transfer char- acteristics of cadmium and lead from soil to the edible parts of six vegetable species in southeastern China 显示文摘 | Wang Guo Su Miaoyu Chen Yanhui | 2006 | Environmen- tal Pollution2006，144，1： | 1 |
| 7 | Efficacy of Ciji Hua'ai Baosheng formula on the expressions of vascular endothelial growth factor,kinase insert domain-containing receptor and basic fibroblast growth factor in mouse models of H22 hepatocellular carcinoma显示文摘OBJECTIVE: To investigate the efficacy of Ciji Hua'ai Baosheng formula(CHBF) on microvessel density(MVD) and vascular endothelial growth factor(VEGF), kinase insert domain-containing receptor(KDR) and basic fibroblast growth factor(b FGF) expression in serum and tumor tissue of mice receiving chemotherapy for the treatment of H22 hepatocellular carcinoma.METHODS: Sixty Kunming mice were injected subcutaneously with H22 hepatoma carcinoma cell suspensions into the right anterior armpit. Seven days later, all transplanted tumor were formed and the mice were intraperitoneally injected 200 mg/kg cytoxan(CTX) to establish the models of tumor-bearing mouse chemotherapy, then they were randomly divided into model group, continuing CTX chemotherapy group(CTX group), and three CHBF(117, 58.5 and 29.25 g/kg) groups. After ten days of treatments, histology was observed, contents of VEGF, KDR and b FGF in serum and tumor tissue were measured by enzyme-linked immunosorbent assay(ELISA), VEGF and b FGF protein expression and MVD tagged by CD34 were detected by immunohistochemisty.RESULTS: MVD in CHBF(117, 58.5 g/kg) and CTX groups was significantly lower than that in model group(P < 0.01); expressions of VEGF, KDR and b FGF in serum and tumor tissue in CHBF(117 g/kg)group were less than those in model group(P <0.05; P < 0.01); the expressions of MVD, VEGF and b FGF in tumor tissue of CHBF(117 g/kg) groupwere also less than those in CTX group(P < 0.05;P < 0.01).CONCLUSION: CHBF can effectively reduce the expression of VEGF, KDR and b FGF in serum and tumor tissue, and decrease MVD and delay tumor progression. | Zhao Xinyue Xi Shengyan Wang Yanhui Xu Yangxinzi Pollock Galia Su Yu Cheng Yao Loy Guanjie Liu Pei | 2017 | Journal of Traditional Chinese Medicine2017，37，1： | 1 |
| 8 | Transfer characteristics of cadmium and lead from soil to the edible parts of six vegetable species in southeastern China 显示文摘 | WAN Guo SU Miaoyu CHEN Yanhui | 2006 | Environmental Pollution2006，144，： | 1 |
| 9 | Determination of norfloxacin in human urine by capillary electrophoresis with electrochemiluminescence detection显示文摘 | Biyang Deng Caina Su Yanhui Kang | 2006 | Analytical and Bioanalytical Chemistry2006，，7： | 1 |
| 10 | Genomic identification of direct target genes of LEAFY 显示文摘 | WILLIAM D A SU Yanhui SMITH M R | 2004 | Proc Natl Acad Sci USA2004，101，6： | 1 |
| 11 | Transfercharacteristics of cadmium and lead from soil to the edibleparts of six vegetable species in southeastern China显示文摘 | Wang Guo Su Miaoyu Chen Yanhui | 2006 | Environmental Pollution2006，144，1： | 1 |
| 12 | Fast-chargingand dendrite-free lithiummetal anodeeenabledby partial lithiation ofgraphene aerogel显示文摘The development of deeply cyclable lithium metal batteries with fast-charging capability offers a promising solution to relieve the“range anxiety”in driving electric vehicles.Conventional lithium metal anodes suffered from low operating current densities and shallow charge/discharge depths,owing to the intrinsic dendrite growth governed by Sand’s law.Herein,we come up with a novel design of heavy-duty lithium metal anode fabricated by partially infusing the three-dimensional(3D)porous graphene aerogel with molten Li.Both electroanalytical measurements and simulations show that the unique electrode architecture brings notable advantages in mediating smooth Li plating/stripping,including reduced local current density,inhibited dendrite growth,buffered volume fluctuation,as well as more efficient Li utilization.Consequently,a remarkable cycling performance in symmetric cells for over 400 cycles(800 h)with an ultrahigh cycling capacity of 15 mAh·cm^(−2) at 15 mA·cm^(−2) is achieved,which,to our best knowledge,has been never seen in literature.LiFePO4 full cells demonstrate a superb rate capability up to 10 C and a prolonged cycling of 1,600 cycles at 2 C with the per-cycle capacity decay of only 0.023%.This study paves the way for the ultimate deployment of lithium metal batteries in real-world applications that require fast charging and deep cycling. | Yong Ma Yuting Gu Ying He Le Wei Yuebin Lian Weiyi Pan Xinjian Li Yanhui Su Yang Peng Zhao Deng Zhongfan Liu | 2022 | Nano Research2022，15，11： | 1 |
| 13 | Determination of norfloxacin in human urine by capillary electrophoresis with eleetroehemilumineseenee deteetion显示文摘 | DENG Biyang SU Caina KANG Yanhui | 2006 | Anal Bioanal Chem2006，385，： | 1 |
| 14 | Multi-Scale Design and Optimization of Composite Material Structure for Heavy-Duty Truck Protection Device显示文摘In this paper,to present a lightweight-developed front underrun protection device(FUPD)for heavy-duty trucks,plain weave carbon fiber reinforced plastic(CFRP)is used instead of the original high-strength steel.First,the mechanical and structural properties of plain carbon fiber composite anti-collision beams are comparatively analyzed from a multi-scale perspective.For studying the design capability of carbon fiber composite materials,we investigate the effects of TC-33 carbon fiber diameter(D),fiber yarn width(W)and height(H),and fiber yarn density(N)on the front underrun protective beam of carbon fiber compositematerials.Based on the investigation,a material-structure matching strategy suitable for the front underrun protective beam of heavy-duty trucks is proposed.Next,the composite material structure is optimized by applying size optimization and stack sequence optimization methods to obtain the higher performance carbon fiber composite front underrun protection beam of commercial vehicles.The results show that the fiber yarn height(H)has the greatest influence on the protective beam,and theH1matching scheme for the front underrun protective beamwith a carbon fiber composite structure exhibits superior performance.The proposed method achieves a weight reduction of 55.21% while still meeting regulatory requirements,which demonstrates its remarkable weight reduction effect. | Yanhui Zhang Lianhua Ma Hailiang Su Jirong Qin Zhining Chen Kaibiao Deng | 2024 | Computer Modeling in Engineering & Sciences2024，139，5： | 0 |
| 15 | Electrochemical CO_(2) reduction catalyzed by organic/inorganic hybrids显示文摘Electroreduction of CO_(2) into value-added chemicals and fuels utilizing renewable electricity offers a sustainable way to meet the carbon-neutral goal and a viable solution for the storage of intermittent green energy sources.At the core of this technology is the development of electrocatalysts to accelerate the redox kinetics of CO_(2) reduction reactions(CO_(2)RR)toward high targeted-product yield at minimal energy input.This perspective focuses on a unique category of CO_(2)RR electrocatalysts embodying both inorganic and organic components to synergistically promote the reaction activity,selectivity and stability.First,we summarize recent progress on the design and fabrication of organic/inorganic hybrids CO_(2)RR electrocatalysts,with special attention to the assembly protocols and structural configurations.We then carry out a comprehensive discussion on the mechanistic understanding of CO_(2)RR processes tackled jointly by the inorganic and organic phases,with respect to the regulation of mass and charge transport,modification of double-layer configuration,tailoring of intermediates adsorption,and establishment of tandem pathways.At the end,we outline future challenges in the rational design of organic/inorganic hybrids for CO_(2)RR and further extend the scope to the device level.We hope this work could incentivize more research interests to construct organic/inorganic hybrids for mobilizing electrocatalytic CO_(2)RR towards industrialization. | Daqi Song Yuebin Lian Min Wang Yanhui Su Fenglei Lyu Zhao Deng Yang Peng | 2023 | eScience2023，3，2： | 0 |
| 16 | Polypyrrole reinforced ZIF-67 with modulated facet exposure and billion-fold electrical conductivity enhancement towards robust photocatalytic CO_(2) reduction显示文摘The implementation of metal organic frameworks(MOFs) as the co-catalysts in hybrid photocatalytic systems puts requirements on both their charge-carrying capability and solvent stability. In the current study, in order to simultaneously promote the electrical conductivity and water stability of ZIF-67, an insitu monomer trapping strategy is deployed to synthesize polypyrrole(PPy)-reinforced ZIF-67 ensembles.Through coordination modulation, the incremental addition of pyrrole monomers enables to alter the crystal morphology of ZIF-67 from rhombic dodecahedra to truncated rhombic dodecahedra, and further to cubes. Upon polymerization, the resulted composite, in comparison to ZIF-67, demonstrates a billionfold conductivity enhancement, much improved chemical stability in pronated solvents, as well as largely retained specific surface area and porosity, enabling it functioning as an outstanding co-catalyst for catalyzing robust photocatalytic CO_(2) reduction. Furthermore, a PPy-mediated electron harvest and relay mechanism is proposed for rationalizing the enhanced photocatalytic performance. | Xuzhou Yuan Qiaoqiao Mu Songlin Xue Yanhui Su Yanlei Zhu Hao Sun Zhao Deng Yang Peng | 2021 | Journal of Energy Chemistry2021，30，9： | 0 |
| 17 | Hydroxylated metal–organic-layer nanocages anchoring single atomic cobalt sites for robust photocatalytic CO_(2) reduction显示文摘Assembly of two-dimensional(2D)metal–organic layers(MOLs)based on the hard and soft acid–base theorem represents an exquisite strategy for the construction of photocatalytic platforms in virtue of the highly exposed active sites,much improved mass transport,and greatly elevated stability.Herein,nanocages composed of MOLs are produced for the first time through a cosolvent approach utilizing zirconium-based UiO-66-(OH)2 as the structural precursor.To endow the catalytic activity for CO_(2) conversion,single atomic Co^(2+)sites are appended to the Zr-oxo nodes of the MOL cages,demonstrating a remarkable CO yield of 7.74 mmol·g^(-1)·h^(-1) and operational stability of 97.1%product retention after five repeated cycles.Such an outstanding photocatalytic performance is mainly attributed to the unique nanocage morphology comprising enormous 2D nanosheets for augmented Co^(2+)exposure and the abundant surface hydroxyl groups for local CO_(2) enrichment.This work underlines the tailoring of both metal–organic framework(MOF)morphology and functionality to boost the turnover rate of photocatalytic CO_(2) reduction reaction(CO_(2)RR). | Weiyi Pan Zhihe Wei Yanhui Su Yuebin Lian Zhangyi Zheng Huihong Yuan Yongze Qin Xulan Xie Qianqian Bai Zhenyang Jiao Wei Hua Jinzhou Chen Wenjun Yang Zhao Deng Yang Peng | 2024 | Nano Research2024，17，4： | 0 |
| 18 | Introduction to the Special Issue on Blockchain Security显示文摘Motivated by the fast evolvement of blockchain technology,cloud-edge platforms,intelligent transportation systems,smart grid,vehicular networks,location based services,and other IoT applications have achieved significant breakthrough during recent years.Nowadays,blockchain based researches and projects are super-hot topics and focuses for both research and industrial communities.However,most of the current blockchain projects still suffer from insufficient security concerns.The defects of the underlying protocol make the node communication vulnerable to be hijacked,and further exacerbate the fork problem;smart contracts can hardly be fully tested before deployment because of the evolving blockchain platforms,while the smart contracts updating is impossible(or very complicated);current data privacy protection techniques are either inefficient or inaccurate;sharing and cross-chain schemes brought new security problems together with its TPS promotion.The intrinsic security vulnerabilities make the current blockchain based systems and architectures prone to be assaulted,and further do harm to the confidence of the investment on the blockchain industrial.Worse still,blockchain turns out to play a critical role in a lot of existing security solutions,which would be useless if the blockchain is insecure. | Zhihong Tian Yanhui Guo Shen Su Hui Lu | 2023 | Computer Modeling in Engineering & Sciences2023，，1： | 0 |
| 19 | The ecological adaptability of cloned sheep to free-grazing in the Tengger Desert of Inner Mongolia,China显示文摘Since the birth of the first cloned sheep,somatic cell nuclear transfer technology has been successfully used to clone a variety of mammals.Cloned livestock have no apparent health risks,and the quality and safety of the cloned animal products are similar to non-cloned animals.The social behavior and environmental adaptability of postnatal cloned animals,especially when used for grassland farm production purposes,is unknown.In the present study,the cloned Dorper sheep equipped with GPS location devices were free-grazed in a harsh natural environment similar to conditions commonly experienced by Mongolian sheep.The main findings of this research were as follows.(1)Under free-grazing conditions,the cloned sheep showed excellent climatic and ecological adaptability.In extreme temperature conditions ranging from–30 to 40°C,the cloned sheep maintained acceptable body condition and behaved as other sheep.(2)The cloned sheep quickly adapted from a herd feeding strategy to the harsh environment and quickly exhibited a grazing regimen as other free-grazing sheep.(3)The cloned sheep exhibited free-grazing patterns and social behavior as other sheep.(4)The cloned sheep in the harsh environment thrived and produced healthy lambs.Overall,the cloned Dorper sheep exhibited excellent ecological adaptation,which is an important consideration for breeding meat sheep by cloning.The Dorper sheep readily adapted to the free-grazing conditions on the Mongolian plateau grassland,which attests to their ability to withstand harsh environmental conditions. | Xinxin LI Huijuan WANG Guanghua SU Zhuying WEI Chunling BAI Wuni-MENGHE Yanhui HOU Changqing YU Shorgan BOU Guangpeng LI | 2014 | Frontiers of Agricultural Science and Engineering2014，1，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员