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| 1 | Suppressed expression of miR-378 targeting gzmb in N cells is required to control dengue virus infection显示文摘 | Shuyan Liu Lingming Chen Ying Zeng Lulu Si Xiaolan Guo Junmei Zhou Danyun Fang Gucheng Zeng Lifang Jiang | 2016 | Cellular & Molecular Immunology2016,13,5: | 7 |
| 2 | Th1 cytokines, true functional signatures for protective immunity against TB?显示文摘The lack of an effective preventative vaccine against tuberculosis(TB)presents a great challenge to TB control.Since it takes an extremely long time to accurately determine the protective efficacy of TB vaccines,there is a great need to identify the surrogate signatures of protection to facilitate vaccine development.Unfortunately,antigen-specific Th1 cytokines that are currently used to evaluate the protective efficacy of the TB vaccine,do not align with the protection and failure of TB vaccine candidates in clinical trials.In this review,we discuss the limitation of current Th1 cytokines as surrogates of protection and address the potential elements that should be considered to finalize the true functional signatures of protective immunity against TB. | Gucheng Zeng Guoliang Zhang Xinchun Chen | 2018 | Cellular & Molecular Immunology2018,15,3: | 6 |
| 3 | PROBING MOLECULAR INTERACTION BETWEEN TRANSFERRIN AND ANTI-TRANSFERRIN BY ATOMIC FORCE MICROSCOPE显示文摘The interaction between transferrin (Tf) and its antibody was investigated by atomic force microscope. Tf-antibody was immobilized on the Au-coated glass slide, and the specific combination between antibody and antigen was also character-ized by AFM. The results showed that holo-transferrin was jogged with anti-transferrin, and binded anti-tran- sferrin more tightly than apo-transferrin. The force- distance curves revealed that the affinity of anti-trans- ferrin and holo-transferrin was much stronger than that of apo-transferrin. | ZHENG Zhiwen YANG Peihui ZENG Gucheng CAI Jiye | 2006 | Chinese Science Bulletin2006,51,4: | 3 |
| 4 | Nanostructures and molecular force bases of a highly sensitive capacitive immunosensor显示文摘 | ZENG Gucheng YANG Peihui ZHENG Zhiwen | 2005 | Proteomics2005,5,17: | 1 |
| 5 | Nutrition Metabolism and Infections显示文摘Infection and nutrition are intricately interacted and further influence human health.Infections are a worldwide health problem and malnutrition plays a significant role in the emergence of infection.Growing evidence suggests that the optimization of dietary nutrients intake is crucial in maintaining systemic immunity and may help improve resistance to infections.In this review,we explore a wide range of topics including interactions between nutrients and various infectious diseases.We also discuss the role of diet-induced gut microbiota in the infection-nutrition cycle and review how dietary-microbiome crosstalk may affect disease development and progression,which may provide an attractive option to the design of a diet leading to favorable outcomes in the future.We will also present evidence and propose mechanisms of nutrients that may specifically modulate host immunity and metabolism to infectious pathogens and also cover its influence on nutrition,focusing on immuno-nutrients.We provide representative nutrients in the present review based on their intensive studies and wide acceptance of their immuno-modulating properties.Moreover,the efficacy and translational cost of their plausible utility to be anti-infective nutrients are also reviewed.Finally,we highlight the current progress and challenges to gain a better understanding of the research into microbiota,infectious diseases,and nutrition with an emphasis on future research directions. | Fang Yang Yi Yang Lingchan Zeng Yiwei Chen Gucheng Zeng | 2021 | Infectious Microbes & Diseases2021,3,3: | 1 |
| 6 | Non-coding RNA: a key regulator of the pathogenicity and immunity of Flaviviridae viruses infection显示文摘Flaviviridae is a family of viruses that mainly spread through arthropod vectors,such as mosquitoes.Major members of the Flaviviridae family include dengue virus(DENV),yellow fever virus,Zika virus(ZIKV),West Nile virus and hepatitis C virus(HCV).As Flaviviridae viruses remain a major global public health threat,elucidation of the exact mechanisms of pathogenesis during infection is required for the successful control of these deadly viruses. | Zhiyi Zhang Lifang Jiang Gucheng Zeng | 2018 | Cellular & Molecular Immunology2018,15,2: | 0 |
| 7 | Neutrophils, reverse traffic and detrimental potential显示文摘 | Gucheng Zeng Zheng W. Chen | 2012 | Cellular & Molecular Immunology2012,9,2: | 0 |
| 8 | Progress and challenges in multi-stack fuel cell system for high power applications:Architecture and energy management显示文摘With the development of fuel cells,multi-stack fuel cell system(MFCS)for high power application has shown tremendous development potential owing to their obvious advantages including high efficiency,durability,reliability,and pollution-free.Accordingly,the state-of-the-art of MFCS is summarized and analyzed to advance its research.Firstly,the MFCS applications are presented in high-power scenarios,especially in transportation applications.Then,to further investigate the MFCS,MFCS including hydrogen and air subsystem,thermal and water subsystem,multi-stack architecture,and prognostics and health monitoring are reviewed.It is noted that prognostics and health monitoring are investigated rarely in MFCS compared with previous research.In addition,the efficiency and durability of MFCS are not only related to the application field and design principle but also the energy management strategy(EMS).The reason is that the EMS is crucial for lifespan,cost,and efficiency in the multi-stack fuel cell system.Finally,the challenge and development potential of MFCS is proposed to provide insights and guidelines for future research. | Yuqi Qiu Tao Zeng Caizhi Zhang Gucheng Wang Yaxiong Wang Zhiguang Hu Meng Yan Zhongbao Wei | 2023 | Green Energy and Intelligent Transportation2023,2,2: | 0 |