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| 1 | TSR promotes the formation of oil-cracking gases: Evidence from simulation experiments显示文摘TSR is an interaction between sulfate and hydrocarbons, occurring widely in carbonate reservoirs. Because this process can produce a large amount of noxious acidic gases like H2S, it has drawn seri- ous concern recently. This paper reports an experiment that simulated an interaction between different minerals and hydrocarbon fluids under different temperature and time using a confined gold-tube system. The results showed that the main mineral that initiates TSR is MgSO4, and adding a certain amount of NaCl into the reactive system can also promote TSR and yield more H2S. The H2S produced in TSR is an important incentive for the continuous oxidative degradation of crude oils. For instance, the yield of oil-cracking gases affected by TSR was twice of that not affected by TSR while the yield of TSR-affected methane was even higher, up to three times of that unaffected by TSR. The carbon iso- topes of wet gases also became heavier. All of the above illustrated that TSR obviously motivates the oxidative degradation of crude oils, which makes the gaseous hydrocarbon generation sooner and increases the gas dryness as well. The study on this process is important for understanding the TSR mechanism and the mechanism of natural gas generation in marine strata. | ZHANG ShuiChang SHUAI YanHua ZHU GuangYou | 2008 | Science China Earth Sciences2008，51，3： | 18 |
| 2 | Discrimination of abiogenic and biogenic alkane gases显示文摘We have combined the analytical data of the carbon isotope distribution pattern, R/Ra and CH4/3He values of abiogenic and biogenic (referring to the thermogenic and bacterial or microbial) alkane gases in China with those of alkane gases from USA, Russia, Germany, Australia and other countries. Four discrimination criteria are derived from this comparative study: 1) Carbon isotopic composition is generally greater than -30‰ for abiogenic methane and less than -30‰ for biogenic methane; 2) Abiogenic alkane gases have a carbon isotopic reversal trend (δ 13C1> δ 13C2> δ 13C3> δ 13C4) with δ 13C1>-30‰ in general; 3) Gases with R/Ra >0.5 and δ 13C11 δ 13C2>0 are of abiogenic origin; 4) Gases (meth- ane) with CH4/3He≤106 are of abiogenic origin, whereas gases with CH4/3He≥1011 are of biogenic origin. | DAI JinXing ZOU CaiNeng ZHANG ShuiChang LI Jian NI YunYan HU GuoYi LUO Xia TAO ShiZhen ZHU GuangYou MI JingKui LI ZhiSheng HU AnPing YANG Chun ZHOU QingHua SHUAI YanHua ZHANG Ying MA ChengHua | 2008 | Science China Earth Sciences2008，51，12： | 17 |
| 3 | Efficient Algorithm for K-Barrier Coverage Based on Integer Linear Programming显示文摘Barrier coverage of wireless sensor networks is an important issue in the detection of intruders who are attempting to cross a region of interest.However,in certain applications,barrier coverage cannot be satisfied after random deployment.In this paper,we study how mobile sensors can be efficiently relocated to achieve k-barrier coverage.In particular,two problems are studied:relocation of sensors with minimum number of mobile sensors and formation of k-barrier coverage with minimum energy cost.These two problems were formulated as 0–1 integer linear programming(ILP).The formulation is computationally intractable because of integrality and complicated constraints.Therefore,we relax the integrality and complicated constraints of the formulation and construct a special model known as RELAX-RSMN with a totally unimodular constraint coefficient matrix to solve the relaxed 0–1 ILP rapidly through linear programming.Theoretical analysis and simulation were performed to verify the effectiveness of our approach. | Yanhua Zhang Xingming Sun Baowei Wang | 2016 | China Communications2016，13，7： | 14 |
| 4 | The role of maize root size in phosphorus uptake and productivity of maize/faba bean and maize/wheat intercropping systems显示文摘Interspecific root/rhizosphere interactions affect phosphorus (P) uptake and the productivity of maize/faba bean and maize/wheat intercropping systems. The aim of these experiments was to determine whether manipulation of maize root growth could improve the productivity of the two intercropping systems. Two near isogenic maize hybrids (the larger-rooted T149 and smaller-rooted T222) were intercropped with faba bean and wheat, under conditions of high- and low-P availability. The larger-rooted T149 showed greater competitive ability than the smaller-rooted T222 in both maize/faba bean and maize/wheat intercropping systems. The higher competitive ability of T149 improved the productivity of the maize/faba bean intercropping system in P-sufficient conditions. In maize/wheat intercropping systems, root growth, shoot biomass, and P uptake of maize were inhibited by wheat, regardless of the P-supply. Compared with T222, the larger-rooted T149 suffered less in the intercropping systems. The total biomass of the maize/wheat intercropping system was higher for wheat/T149 than for wheat/T222 under low-P conditions. These data suggested that genetic improvement of maize root size could enhance maize growth and its ability to compete for P resources in maize/faba bean and maize/wheat intercropping systems. In addition, depending on the P availability, larger maize roots could increase the productivity of intercropping systems. | ZHANG YiKai CHEN FanJun LI Long CHEN YanHua LIU BingRan ZHOU YuLing YUAN LiXing ZHANG FuSuo MI GuoHua | 2012 | Science China(Life Sciences)2012，55，11： | 13 |
| 5 | The study on the safety and efficacy of amnion graft for preventing the recurrence of moderate to severe intrauterine adhesions显示文摘Transcervical resection of adhesion(TCRA)is the standard treatment for the intrauterine adhesions,but the recurrence of adhesions is a tough problem for the gynecologist.In addition,the therapeutic strategy after TCRA about prevention of recurrence remains controversial especially for the patients with moderate to severe intrauterine adhesions(IUAs).Hence,we designed this study to explore the safety and efficacy of fresh amnion grafts for preventing the recurrence after TCRA for patients with moderate to severe IUAs.One hundred patients with moderate to severe IUAs who presented with a history of hypomenorrhea,amenorrhea and infertility were included in the study from January 2015 to December 2017.Patients were divided into amnion group(52 patients)and chitosan group(48 patients).Fresh amnion grafts or intrauterine injections of chitosan were administered after TCRA.Transvaginal ultrasonography(TVUS)and hysteroscopy were performed at the first and third month after the operation.The surgical procedures for all patients were completed successfully without relevant complications.In amnion group,8 patients exhibited relapse in the first month and 2 patients in three months after surgery;in chitosan group,23 women exhibited relapse in the first month and 18 patients in three months after surgery.Statistical analysis revealed that the recurrence rate of adhesion in amnion group was significantly lower than those of chitosan group in the first and three months after surgery(P1=0.000,P2=0.000).After TCRA,fresh amnion graft plays a significant role in preventing further adhesions than injections of chitosan. | Changjiang Li Aiqi Cai Congcong Sun Benyuan Wu Xinpei Chen Yanhua Mao Yingfeng Zhang Yating Gou Jie Yu Yuhan Wang Huanhuan Yu Jia Wang | 2020 | Genes & Diseases2020，7，2： | 11 |
| 6 | A New Gigantic Sauropod Dinosaur with the Deepest Known Body Cavity from the Cretaceous of Asia显示文摘摘要:sauropod 恐龙 Huanghetitan ruyangensis 的新种基于下列人物被树立:有到达至少 2.93 m 的一根背面的肋骨的最深的身体洞有塑造蘑菇的神经脊骨的长、前面的尾的 vertebrae。基于在 Ruyang 的早迟了的白垩纪 Mangchuan 形成发现的 Huanghetitan 的这个新标本,河南省省,家庭 Huanghetitanidae fam。nov。作为一个新等级被建议包括仅仅类尤胡昂黑蒂坦等。2006。目前, Huanghetitan 包括二种:H。liujiaxiaensis 你等, 2006 并且 H。ruyangensis sp。nov。在 sauropod 恐龙之中的 Huanghetitan 的系统的关系简短被讨论。 | XU Li ZHANG Xingliao HU Weiyong WU Yanhua JIA Songhai JI Qiang | 2007 | Acta Geologica Sinica(English Edition)2007，81，2： | 10 |
| 7 | Metformin targets multiple signaling pathways in cancer显示文摘Metformin,an inexpensive and well-tolerated oral agent commonly used in the first-line treatment of type 2 diabetes,has become the focus of intense research as a candidate anticancer agent.Here,we discuss the potential of metformin in cancer therapeutics,particularly its functions in multiple signaling pathways,including AMP-activated protein kinase,mammalian target of rapamycin,insulin-like growth factor,c-Jun N-terminal kinase/mitogen-activated protein kinase(p38 MARK),human epidermal growth factor receptor-2,and nuclear factor kappaB pathways.In addition,cutting-edge targeting of cancer stem cells by metformin is summarized. | Yong Lei Yanhua Yi Yang Liu Xia Liu Evan T.Keller Chao.Nan Qian Jian Zhang Yi Lu | 2017 | Chinese Journal of Cancer2017，36，7： | 9 |
| 8 | The origin of Wx^(la) provides new insights into the improvement of grain quality in rice显示文摘Appearance and taste are important factors in rice(Oryza sativa) grain quality. Here, we investigated the taste scores and related eating-quality traits of533 diverse cultivars to assess the relationships between—and genetic basis of—rice taste and eating-quality. A genome-wide association study highlighted the Wx gene as the major factor underlying variation in taste and eating quality. Notably, a novel waxy(Wx) allele, Wx^(la), which combined two mutations from Wx^(b) and Wx^(in), exhibited a unique phenotype. Reduced GBSSI activity conferred Wx^(la) rice with both a transparent appearance and good eating quality. Haplotype analysis revealed that Wx^(la) was derived from intragenic recombination. In fact,the recombination rate at the Wx locus was estimated to be 3.34 kb/c M, which was about 75-fold higher than the genome-wide mean, indicating that intragenic recombination is a major force driving diversity at the Wx locus. Based on our results, we propose a new network for Wx evolution, noting that new Wx alleles could easily be generated by crossing genotypes with different Wx alleles. This study thus provides insights into the evolution of the Wx locus and facilitates molecular breeding for quality in rice. | Hao Zhou Duo Xia Da Zhao Yanhua Li Pingbo Li Bian Wu Guanjun Gao Qinglu Zhang Gongwei Wang Jinghua Xiao Xianghua Li Sibin Yu Xingming Lian Yuqing He | 2021 | Journal of Integrative Plant Biology2021，63，5： | 8 |
| 9 | Effect and quantitative evaluation of CO_2 derived from organic matter in coal on the formation of tight sandstone reservoirs显示文摘Tight reservoirs are widely distributed, especially in coal measure strata. Identification of the densification mechanism of the tight sandstone reservoirs is critical in effectively exploring and exploiting tight gas/oil resources. In this study, the gas formation from type Ⅲ organic matter in coal was kinetically modeled for the whole diagenetic stage, from the shallow buried biogas generation stage to the deep buried thermal gas generation stage. The results demonstrated that during hydrocarbon formation, quantities of non-hydrocarbon gases, such as CO2 , were generated. The proportion of CO2 is about 50%-70% of that of the C1-5 , which far exceeds the CO2 content (0-5%) in the natural gas in the sedimentary basins. Geological case study analysis showed that a considerable part of the 'lost' gaseous CO2 was converted into carbonate cement under favorable environments. Under the ideal conditions, the volume of the carbonate cement transformed from total CO 2 generated by 1 m 3 coal (Junggar Basin Jurassic, TOC 67%) can amount to 0.32 m 3 . Obviously, this process plays a very important role in the formation of tight sandstone reservoirs in the coal measures. Our results also show that the kinetic generation processes of C1-5 and CO2 are asynchronous. There are two main stages of CO2 generation, one at the weak diagenetic stage and the other at the over-mature stage, which are different from large-scale multi-stage hydrocarbon gas generation. Therefore, we can understand the mechanism of tight gas charging by determining the filling time for a tight gas reservoir and the key period of CO2 generation. Further analysis and correlation studies of a specific region are of great significance for determining the mechanism and modeling gas charging in tight reservoirs. It should be noted that the formation of tight sandstone reservoirs is the combined result of complex organic-inorganic and water-rock-hydrocarbon interactions. The details of spatial and temporal distributions of the carbonate cement derived from the organic CO2 , which combines with metal ions (Ca/Mg/Fe) in the formation water, should be further investigated. | SHUAI YanHua ZHANG ShuiChang GAO Yang LU Hong CHEN JianPing MI JingKui LIU JinZhong HU GuoYi | 2013 | Science China Earth Sciences2013，56，5： | 7 |
| 10 | Newborn screening with targeted sequencing:a multicenter investigation and a pilot clinical study in China显示文摘Different newborn screening(NBS) programs have been practiced in many countries since the 1960 s. It is of considerable interest whether next-generation sequencing is applicable in NBS. We have developed a panel of 465 causative genes for 596 early-onset, relatively high incidence, and potentially actionable severe inherited diseases in our Newborn Screening with Targeted Sequencing(NESTS) program to screen 11,484 babies in 8 Women and Children’s hospitals nationwide in China retrospectively. The positive rate from preliminary screening of NESTS was 7.85%(902/11,484). With 45.89%(414/902) follow-up of preliminary positive cases, the overall clinically confirmative diagnosis rate of monogenic disorders was 12.07%(50/414), estimating an average of 0.95%(7.85% × 12.07%) clinical diagnosis rate, suggesting that monogenic disorders account for a considerable proportion of birth defects. The disease/gene spectrum varied in different regions of China. NESTS was implemented in a hospital by screening 3923 newborns to evaluate its clinical application. The turn-around time of a primary report, including the sequencing period of < 7 days, was within 11 days by our automatic interpretation pipeline. Our results suggest that NESTS is feasible and cost-effective as a first-tier NBS program, which will change the status of current clinical practice of NBS in China. | Chanjuan Hao Ruolan Guo Xuyun Hu Zhan Qi Qi Guo Xuanshi Liu Yuanhu Liu Yanhua Sun Xiaofen Zhang Feng Jin Xiujie Wu Ren Cai Dingyuan Zeng Xijiang Hu Xiaohua Wang Xiaoping Ji Wenjie Li Quansheng Xing Lanfang Mu Xiulian Jiang Xue Yang Weimin Yang Yan Zhang Qianli Yin Xin Ni Wei Li | 2022 | Journal of Genetics and Genomics2022，49，1： | 7 |
| 11 | QoS-Aware Dynamic Resource Management in Heterogeneous Mobile Cloud Computing Networks显示文摘In mobile cloud computing(MCC) systems,both the mobile access network and the cloud computing network are heterogeneous,implying the diverse configurations of hardware,software,architecture,resource,etc.In such heterogeneous mobile cloud(HMC) networks,both radio and cloud resources could become the system bottleneck,thus designing the schemes that separately and independently manage the resources may severely hinder the system performance.In this paper,we aim to design the network as the integration of the mobile access part and the cloud computing part,utilizing the inherent heterogeneity to meet the diverse quality of service(QoS)requirements of tenants.Furthermore,we propose a novel cross-network radio and cloud resource management scheme for HMC networks,which is QoS-aware,with the objective of maximizing the tenant revenue while satisfying the QoS requirements.The proposed scheme is formulated as a restless bandits problem,whose 'indexability' feature guarantees the low complexity with scalable and distributed characteristics.Extensive simulation results are presented to demonstrate the significant performance improvement of the proposed scheme compared to the existing ones. | SI Pengbo ZHANG Qian F. Richard YU ZHANG Yanhua | 2014 | China Communications2014，11，5： | 7 |
| 12 | Nicotine-induced upregulation of antioxidant protein Prx 1 in oral squamous cell carcinoma显示文摘Nicotine is a source of exogenous oxidative stress, which is associated with the pathogenesis of numerous diseases including oral squamous cell carcinoma (OSCC), whereas an antioxidant protein, peroxiredoxin 1 (Prx 1), plays an important role in the modulation of this condition. This study was to investigate the association between Prx 1 and tobacco-induced oxidative stress. The expression of Prx 1 and GST in OSCC Tca8113 cells, which were pre-treated with nicotine, was determined. In the present study, MTT assay, reactive oxygen species (ROS) assay, RT-PCR and Western blot analyses, respectively, were conducted to assess cell viability, ROS level, and expression level of Prx 1 and GST in nicotine-treated Tca8113 cells. Nuclear factor kappa B (NF- B) expression was detected by immuno-fluorescence. Our results showed the growth of Tca8113 cells was increased in a dose-dependent manner when cells were treated with nicotine at concentrations from 0.1 to 10 mol/L, but the proliferation of the cells decreased at 100 mol/L. ROS levels increased in all groups treated with nicotine at concentrations of 0.1, 1, 10, or 100 mol/L for 24h. Prx 1 and GST mRNA and protein expression were up-regulated in cells treated with nicotine for the same time at different concentrations or at the same concentration for different times (P<0.05). NF-B was translocated from cytoplasm to nucleus, the expression of NF- B was increased in nucleus. These results suggest that up-regulation of Prx1 expression appears to be associated with tobacco-induced oxidative stress, which may play an important role in the pathogenesis of OSCC. | ZHAO YanHua ZHANG Min YAN Fei CASTO Bruce C TANG XiaoFei | 2013 | Chinese Science Bulletin2013，58，16： | 7 |
| 13 | Genetic Relationship between Francisella Tularensis Strains from China and from Other Countries显示文摘Objective To study the types of subspecies of Francisella tularensis from China and to investigate the genetic relationships between F.tularensis strains from China and from other countries.Methods Ten strains of F.tularensis isolated from China were amplified by using typing primers C1/C4 and RD1.On the basis of the lengths of the polymerase chain reaction (PCR) products,it was concluded that these strains of F.tularensis belonged to the same subspecies.At the same time,the fopA,tul4,and 16S rRNA genes of the 10 strains were amplified,and a three‐gene based phylogenetic analysis was performed using the Molecular Evolutionary Genetics Analysis software version 4.0.Results The 10 strains of F.tularensis from China were all identified as belonging to subspecies holarctica (type B).We found no direct relationship between the genotypes of F.tularensis subsp.holarctica and the geographical area from where they were isolated.Conclusion The F.tularensis strains isolated from North China mainly belong to subspecies holarctica (type B).The strains of F.tularensis subsp.holarctica from China may have evolved earlier than those from Europe and North America. | WANG YanHua HAI Rong ZHANG ZhiKai XIA LianXu CAI Hong LIANG Ying SHEN XiaoNa YU DongZheng | 2011 | Biomedical and Environmental Sciences2011，24，3： | 7 |
| 14 | Global transcriptome analysis for identification of interactions between coding and noncoding RNAs during human erythroid differentiation显示文摘在 erythroid 开发期间编码基因, miRNAs,和 lncRNAs 上的研究在最近的年里被执行了。然而,集中于三种 RNA 类型的集成的分析还得被做。在现在的学习,我们比较了编码基因, miRNA,和 lncRNA 表示侧面的动力学。为了在在 transcriptome 控制这些变化的红血球生成和潜在的机制探索动态变化,铺平,我们利用了定序技术从绳索血获得 transcriptome 数据的高产量造血的干细胞和下列四个 erythroid 区别阶段,以及从成熟的红血房间。结果显示 lncRNAs 为 erythroid 区别正在答应房间标记候选人。聚类分析分类差别表示基因进在 stemness 维护期间对应于动态变化的四种子类型,中间区别,并且成熟。综合分析揭示了 RNA 潜在地参予了控制血细胞成熟的那 noncoding,并且特别与到氧种类和 DNA 损坏的 heme 新陈代谢和回答联系了。这些规章的相互作用在一个全面网络,在 RNA 之间的从而推断的关联和他们的联系功能被显示。这些数据为正常红血球生成的学习提供了一个大量的资源,它将允许 erythroid 开发的进一步的调查和理解并且获得 erythroid 混乱。 | Nan Ding Jiafei Xi Yanming Li Xiaoyan Xie Jian Shi Zhaojun Zhang Yanhua Li Fang Fang Sihan Wang Wen Yue Xuetao Pei Xiangdong Fang | 2016 | Frontiers of Medicine2016，10，3： | 6 |
| 15 | Decrement of Sugar Consumption in Rice Young Panicle Under High Temperature Aggravates Spikelet Number Reduction显示文摘Two rice genotypes Huanghuazhan(HHZ, heat-resistant) and IR36(heat-susceptible) were subjected to high-temperature(HT, 40℃) and normal-temperature(NT, 32℃) treatments at the spikelet differentiation stage. HT treatment inhibited spikelet differentiation, aggravated spikelet degeneration, reduced spikelet size, and disordered carbohydrate allocation. Meanwhile, HT treatment increased nonstructural carbohydrate content in leaves, but decreased that in stems and young panicles, and the same tendencies of sucrose and starch contents were observed in leaves and stem. However, HT treatment significantly increased the sucrose content and sharply decreased the glucose and fructose contents in young panicles. Lower activity levels of soluble acid invertase(EC3.2.1.26) and sucrose synthase(EC2.4.1.13) were observed under HT treatment. Moreover, HT treatment reduced the activities of key enzymes associated with glycolysis and the tricarboxylic acid cycle, which indicated sucrose consumption was inhibited in young panicles under HT treatment. Exogenous glucose and fructose applied under HT treatment increased the spikelet number more than exogenous sucrose. In conclusion, the results demonstrated that the reduction of spikelet number under high temperature was more affected by the decrease in sugar consumption than the blocking of sucrose transport. The impairment of sucrose hydrolysis was the main reason for the inhibition of sugar utilization. | WANG Yaliang ZHANG Yikai SHI Qinghua CHEN Huizhe XIANG Jing HU Guohui CHEN Yanhua WANG Xiaodan WANG Junke YI Zihao ZHU Defeng ZHANG Yuping | 2020 | Rice science2020，27，1： | 6 |
| 16 | Diversity of root-associated fungi of Vaccinium mandarinorum along a human disturbance gradient in subtropical forests,China显示文摘Aims Ericaceous plant species can host diverse fungi in their roots,including ericoid mycorrhizal fungi(ERMF),endophytes,pathogens and some species with unknown functions.However,how this diversity of fungi responds to different human disturbances is not well understood.Methods In this study,we examined the effects of different human disturbance on fungal diversity in hair roots of Vaccinium mandarinorum,an ericaceous plant.Fungal DNA was extracted from hair roots of V.mandarinorum and high-throughput sequencing was applied to detect the diversity of root-associated fungi along a human disturbance gradient in subtropical forests in Gutianshan National Nature Reserve(GNNR)in East China.The four forest types with different disturbance regime were:old growth forest(OGF),secondary forest with once cut(SEC I),secondary forest with twice cut(SEC II)and Cunninghamia lanceolata plantation(PLF).Important Findings The results showed that:(i)diverse fungal operational units(OTUs)were detected in hair roots of V.mandarinorum in the four types of forests,covering fungal phyla of Ascomycota,Basidiomycota,Chytridiomycota,Glomeromycota and Zygomycota;(ii)Community composition of root-associated fungi of V.mandarinorum in PLF was distinct from those in the other three forest types,and two types of secondary forests had similar fungal community composition;(iii)Different fungal families respond differently to human disturbances:fungal families with significant preference to OGF were ectomycorrhizal or saprophytic fungi while fungal families with higher relative abundance in PLF were plant pathogenic or saprophytic fungi;(iv)The first principal component(PC1)of plant community had a significant effect on composition of root-associated fungal community,while edaphic parameters showed no significant effect on fungal community composition in roots of V.mandarinorum.Our results help to better understand the responses of both ericaceous plants and their fungal partners to human disturbances and forest managements. | Yanhua Zhang Jian Ni Fangping Tang Lifen Jiang Tianrong Guo Kequan Pei Lifu Sun Yu Liang | 2017 | Journal of Plant Ecology2017，10，1： | 6 |
| 17 | Selective transmission and channel estimation in massive MIMO systems显示文摘Massive MIMO systems have got extraordinary spectral efficiency using a large number of base station antennas,but it is in the challenge of pilot contamination using the aligned pilots.To address this issue,a selective transmission is proposed using time-shifted pilots with cell grouping,where the strong interfering users in downlink transmission cells are temporally stopped during the pilots transmission in uplink cells.Based on the spatial characteristics of physical channel models,the strong interfering users are selected to minimize the inter-cell interference and the cell grouping is designed to have less temporally stopped users within a smaller area.Furthermore,a Kalman estimator is proposed to reduce the unexpected effect of residual interferences in channel estimation,which exploits both the spatial-time correlation of channels and the share of the interference information.The numerical results show that our scheme significantly improves the channel estimation accuracy and the data rates. | 杨睿哲 Zong Liang Si Pengbo Ma Dawei Zhang Yanhua | 2016 | High Technology Letters2016，22，1： | 5 |
| 18 | Longitudinal distributions of two formation pathways of biogenic gases in continental deposits: A case study from Sebei 1 gas field in the Qaidam Basin, western China显示文摘The distribution of two formation pathways of biogenic methane, acetate fermentation and reduction of CO2, has been extensively studied. In general, CO2 reduction is the dominate pathway in marine envi- ronment where acetate is relatively depleted because of SRB consuming. While in terrestrial freshwater or brackish environment, acetate fermentation is initially significant, but decreases with increasing buried depth. In this paper, character of biogenic gases is profiled in the XS3-4 well of the Sebei 1 gas field in the Sanhu depression, Qaidam Basin. It indicates that those two pathways do not change strictly with increasing buried depth. CO2 reduction is important near the surface (between 50 m and 160 m), and at the mesozone (between 400 and 1650 m). While acetate fermentation is the primary pathway at two zones, from 160 to 400 m and from 1650 to 1700 m. δ 13C of methane generated in those two acetate fermentation zones varies greatly, owing to different sediment circumstances. At the sec- ond zone (160-400 m), δ 13C1 ranges from ?65‰ to ?30‰ (PDB), because the main deposit is mudstone and makes the circumstance confined. At the fourth zone of the well bottom (1650-1700 m), δ 13C1 is lighter than ?65‰ (PDB). Because the deposit is mainly composed of siltstone, it well connects with outer fertile groundwater and abundant nutrition has supplied into this open system. The high con- centration of acetate is a forceful proof. δ 13C of methane would not turn heavier during fermentation, owing to enough nutrition supply. In spite of multi-occurrence of acetate fermentation, the commercial gas accumulation is dominated by methane of CO2-reduction pathway. A certain content of alkene gases in the biogenic gases suggests that methanogensis is still active at present. | SHUAI YanHua ZHANG ShuiChang ZHAO WenZhi SU AiGuo WANG HuiTong | 2007 | Science China Earth Sciences2007，50，2： | 5 |
| 19 | Geochemical evidence for strong ongoing methanogenesis in Sanhu region of Qaidam Basin显示文摘Sanhu depression of Qaidam Basin is the largest biogenic gas production region in China.Headspace samples were collected from two wells in this region,and hydrogen and propylene compounds were detected in these samples with a certain concentration.The stable hydrogen isotope ratio of H 2 is relatively light (-700‰--820‰).The stable carbon isotope ratio of propylene ranges from -27‰ to -40‰,which coincides with the rule of change of the stable carbon isotope of kerogen at the corresponding horizon.The characteristic analysis of sediments,structures,and Ar and He components in the region indicates that these microelement compounds are the product of degradation of organic substances by microorganisms,rather than from the mantle source,inorganic reaction or other sources.Detection of these components provides solid evidence for the strong ongoing methanogenesis in this region. | YanHua Shuai ShuiChang Zhang AiGuo Su HuiTong Wang BaoYuan Cai Hui Wang | 2010 | Science China Earth Sciences2010，53，1： | 5 |
| 20 | SENP3 regulates the global protein turnover and the Spl level via antagonizing SUM02/ 3-targeted ubiquitination and degradation显示文摘 | Ming Wang Jing Sang Yanhua Ren Kejia Liu Xinyi Liu Jian Zhang Haolu Wang Jian Wang Amir Orian Jie Yang Jing Yi | 2016 | Protein & Cell2016，7，1： | 5 |
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