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| 1 | Accurate relocation of earthquakes in central-western China using the double-difference earthquake location algorithm显示文摘The double-difference earthquake relocation algorithm (DD algorithm) has been applied to the accurate relocation of 10057 earthquakes in the central-western China (21°-36°N, 98°-112E°) during the period of 1992-1999. In total, 79706 readings for P waves and 72169 readings for S waves were used in the relocation, and the source parameters of 6496 events were obtained. The relocation results revealed a more complete picture of the hypocentral distribution in the central-western China. In several seismic belts the relocated epicenters present a more defined lineation feature, reflecting the close correlation between the seismicity and the active tectonic structures. The relocated focal depths confirmed that most earthquakes (91 percent of the 6496 relocated events) in the central-western China were located at shallower depths not deeper than 20 km. The distribution of focal depths indicates that the seismogenic layer in the central-western China is located in the upper-mid crust with its thickness no deeper than 20 km. | YANG Zhixian (杨智娴) CHEN Yuntai (陈运泰) ZHENG Yuejun (郑月军) Yü Xiangwei (于湘伟) | 2003 | Science China Earth Sciences2003，46，z2： | 32 |
| 2 | Baculovirus-mediated expression of a Chinese scorpion neurotoxin improves insecticidal efficacy显示文摘An Buthus martensii Karsch Insect Toxin (BmK IT ) gene was inserted into the genome of Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) to construct a recombinant baculovirus, AcMNPV-BmK IT. The expression of BmK IT was confirmed using RT-PCR, dot blot and SDS-PAGE analysis. Dose-lethal time responses to Spodoptera exigua larvae were compared between wild-type baculovirus AcMNPV and recombinant virus AcMNPV-BmK IT. At the concentration of 1×107 PIBs/mL, the median lethal time of recombinant baculovirus (LT50 = 73.6h) on third instar S. exigua larvae showed an improvement of 13.2% over the efficacy of wild type virus (LT50 = 84.8h) during a 192h in-fection. | FAN XiaoJun ZHENG Bo FU YueJun SUN Yi LIANG AiHua | 2008 | Chinese Science Bulletin2008，53，12： | 7 |
| 3 | An individualized immune signature of pretreatment biopsies predicts pathological complete response to neoadjuvant chemoradiotherapy and outcomes in patients with esophageal squamous cell carcinoma显示文摘No clinically available biomarkers can predict pathological complete response(pCR)for esophageal squamous cell carcinomas(ESCCs)with neoadjuvant chemoradiotherapy(nCRT).Considering that antitumor immunity status is an important determinant for nCRT,we performed an integrative analysis of immune-related gene profiles from pretreatment biopsies and constructed the first individualized immune signature for pCR and outcome prediction of ESCCs through a multicenter analysis.During the discovery phase,14 differentially expressed immune-related genes(DEIGs)with greater than a twofold change between pCRs and less than pCRs( | Chaoqi Zhang Guochao Zhang Nan Sun Zhen Zhang Liyan Xue Zhihui Zhang Haijun Yang Yuejun Luo Xiaoli Zheng Yonglei Zhang Yufen Yuan Ruixue Lei Zhaoyang Yang Bo Zheng Le Wang Yun Che Feng Wang Sihui Wang Shugeng Gao Qi Xue Yi Zhang Jie He | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 7 |
| 4 | Radiolarian fauna found from Tieshidas Group in East Kunlun显示文摘The Tieshidas Group in Qimantag, a branch of the East Kunlun Mountains, was classically considered the Caledonian basement, and classified into Middle-Upper Ordovician, Upper Ordovician or simply Lower Paleozoic. The radiolarian fauna was found, for the first time, from a chert block in the Tieshidas Group at Yaziquandaban (Pass) north to Ayakum Lake. They are Astroentactinia?mirousi Gourmelon, As. cf biaciculata Nazarov, Archocyrtium cf. diductum Deflandre, Ar. aff. diductum Deflandre, Deflandrellium? sp., Entactinia vulgaris Won, En. cf. additiva Foreman, En.? sp., Entactinosphaera palimbola Foreman, Pylentonema? sp., Triaenosphaera sp. and Tr.7 sp. The geological age of this radiolarian fauna is Early Carboniferous. Evidently, the classical interpretation about the age of Tieshidas Group needs to be checked and modified. Except the Ordovician proved with the formerly discovered fossils, it also includes, at least, Lower Carboniferous rocks. There was still an oceanic basin at Qimantag during Early | LI Yuejun JIA Chengzao HAO Jie WANG Zhaoming ZHENG Duoming PENG Gengxin | 2000 | Chinese Science Bulletin2000，45，10： | 2 |
| 5 | Ecosystem functions, services and their values – a case study in Xingshan County of China显示文摘 | Zhongwei Guo Xiangming Xiao Yaling Gan Yuejun Zheng | 2001 | Ecological Economics2001，，1： | 2 |
| 6 | Ecosystem functions, services and their values – a case study in Xingshan County of China显示文摘 | Zhongwei Guo Xiangming Xiao Yaling Gan Yuejun Zheng | 2001 | Ecological Economics2001，，1： | 1 |
| 7 | Azimuthal anisotropy of Rayleigh waves in East Asia 显示文摘 | Zhongxian Huang Yanju Peng Yan Luo Yuejun Zheng Wei Su | 2004 | Geophys Res Letters2004，31，： | 1 |
| 8 | Landscape planning for a rural ecosystem: case study of a resettlement area for residents from land submerged by the Three Gorges Reservoir, China显示文摘 | Zhongwei Guo Xiangming Xiao Yaling Gan Yuejun Zheng | | Landscape Ecology0，，： | 1 |
| 9 | Integrating electromagnetic surface and antenna array for reflection suppression and excellent radiation显示文摘The electromagnetic surface antenna array(EMSAA)has been proposed for obtaining reflection suppression and excellent radiation simultaneously.The antenna with rectangular radiation patch is used to design anisotropic electromagnetic surface.Preternatural reflection characteristics of the element antenna can be tailored depending on the incident polarizations.EMSAA can be constructed by using single structured element antenna with 90° rotation and orthometric arrangement.This orthometric arrangement of EMSAA is helpful to achieve reflection suppression and excellent radiation.The simulated results show that the reflection of EMSAA is suppressed from 5.0 GHz to 8.0 GHz with peak reduction of 12.3 dB.The linear-and circular-polarized radiation properties of EMSAA are obtained and the maximum gain is 14.3 dBi.The measured results are consistent with the simulation results.The results demonstrate that the reflection suppression and excellent radiation are achieved simultaneously.Such design of EMSAA will open the path for integrating antenna fields and electromagnetic surface(EMS)fields. | ZHENG Yuejun DING Liang CHEN Qiang GUO Min FU Yunqi | 2021 | Journal of Systems Engineering and Electronics2021，32，3： | 1 |
| 10 | Emergency Plan for Water Supply in Consecutive Droughts and Sustainable Water Resources Management in Beijing显示文摘Beijing, the capital city of China, has suffered from acute water shortage, with only 300 m3/a of water resources available per capita. In addition, Beijing has experienced a prolonged period of consecutive droughts from 1999 to 2010. Water crisis has constrained the socio-economic development of Beijing. Meanwhile, the national 'South-to-North Water Transfer'(STNWT) project, which is expected to provide some relief to the water crisis in Beijing, is still under development. In order to ensure the security of water supply in Beijing before the completion of the STNWT project, several measures have been implemented to cope with droughts, including pumping groundwater from emergency well fields,water saving, recycling of water, rain and flood water harvesting, and the diversion of water from neighboring rivers and groundwater basins. Groundwater from four emergency well fields contributes the most to the public and domestic water supplies in Beijing, supplying a total volume of 1.8×10~9 m^3.The water crisis is supposed to be mitigated by the completion of the STNWT project. After the completion of this project, more sustainable management of water resources will be implemented,including the use of aquifers as groundwater reservoirs and conjunctive use of surface water and groundwater resources. | LI Wenpeng ZHENG Yuejun YE Chao LI Haitao | 2018 | Acta Geologica Sinica(English Edition)2018，92，3： | 1 |
| 11 | Single-cell analysis reveals the potential mechanisms of pyrotinib resistance in non-small cell lung cancer显示文摘Dear Editor,Lung cancer still remains the leading cause of cancer death worldwide,80-90%of which are non-small cell lung cancer(NSCLC).In 2-3%of NSCLC patients,mutations in human epidermal growth factor receptor 2(HER2)have been identified as oncogenic drivers.However,HER2 has been poorly reported as a therapeutic target for advanced NSCLC despite of the outstanding improvements in breast cancer receiving HER2-targeting regimens. | Xinfeng Wang Yuan Li Runsen Jin Sufei Zheng Yuejun Luo Peng Wu Zhanyu Wang Yuxin Yao Nan Sun Jie He | 2023 | Signal Transduction and Targeted Therapy2023，8，2： | 0 |
| 12 | Electric-controlled metasurface antenna array with ultra-wideband frequency reconfigurable reflection suppression显示文摘The electric-controlled metasurface antenna array(ECMSAA)with ultra-wideband frequency reconfigurable reflection suppression is proposed and realized.Firstly,an electriccontrolled metasurface with ultra-wideband frequency reconfigurable in-phase reflection characteristics is designed.The element of the ECMSAA is constructed by loading the single electric-controlled metasurface unit on the conventional patch antenna element.The radiation properties of the conventional patch antenna and the reflection performance of electric-controlled metasurface are maintained when the antenna and the metasurface are integrated.Thus,the ECMSAA elements have excellent radiation properties and ultra-wideband frequency reconfigurable in-phase reflection characteristics simultaneously.To take a further step,a 6×10 ECMSAA is realized based on the designed metasurface antenna element.Simulated and measured results prove that the reflection of the ECMSAA is dynamically suppressed in the P and L bands.Meanwhile,high-gain and multi-polarization radiation properties of the ECMSAA are achieved.This design method not only realizes the frequency reconfigurable reflection suppression of the antenna array in the ultra-wide frequency band but also provides a way to develop an intelligent low-scattering antenna. | ZHENG Yuejun CHEN Qiang DING Liang YUAN Fang FU Yunqi | 2023 | Journal of Systems Engineering and Electronics2023，34，6： | 0 |
| 13 | A multi-omic landscape of steatosis-to-NASH progression显示文摘Nonalcoholic steatohepatitis(NASH)has emerged as a major cause of liver failure and hepatocellular carcinoma.Investigation into the molecular mechanisms that underlie steatosis-to-NASH progression is key to understanding the development of NASH pathophysiology.Here,we present comprehensive multi-omic profiles of preclinical animal models to identify genes,non-coding RNAs,proteins,and plasma metabolites involved in this progression.In particular,by transcriptomics analysis,we identified Growth Differentiation Factor 3(GDF3)as a candidate noninvasive biomarker in NASH.Plasma GDF3 levels are associated with hepatic pathological features in patients with NASH,and differences in these levels provide a high diagnostic accuracy of NASH diagnosis(AUROC=0.90;95%confidence interval:0.85−0.95)with a good sensitivity(90.7%)and specificity(86.4%).In addition,by developing integrated proteomic-metabolomic datasets and performing a subsequent pharmacological intervention in a mouse model of NASH,we show that ferroptosis may be a potential target to treat NASH.Moreover,by using competing endogenous RNAs network analysis,we found that several miRNAs,including miR-582-5p and miR-292a-3p,and lncRNAs,including XLOC-085738 and XLOC-041531,are associated with steatosis-to-NASH progression.Collectively,our data provide a valuable resource into the molecular characterization of NASH progression,leading to the novel insight that GDF3 may be a potential noninvasive diagnostic biomarker for NASH while further showing that ferroptosis is a therapeutic target for the disease. | Liping Xiang Xiaoyan Li Yunchen Luo Bing Zhou Yuejun Liu Yao Li Duojiao Wu Lijing Jia Pei-Wu Zhu Ming-Hua Zheng Hua Wang Yan Lu | 2022 | Life Metabolism2022，1，3： | 0 |
| 14 | Focal Mechanism Analysis for Determination of Potential Source Zones in South China and Its Adjacent Regions显示文摘Based on the results of focal mechanism solutions in southeastern areas of China (south of 34°N and east of 105°E), this article analyzes the correlation of focal mechanism solutions with seismogenic structures of moderate strong earthquakes and the direction of potential source zones. The data show that the nodal planes of focal mechanism solutions and the principle stresses in southern China are of predominantly similar directions, most of the solutions for M≥4.0 earthquakes correspond to the main structure directions as well as the directions of potential source zones. The statistical results of multiple small earthquakes concerning nodal planes and main stress axes are also reliable for determining the direction of potential source zones. According to the analysis of focal mechanism solutions, long-axis direction of isoseismals distribution of aftershocks, geologic structures, and seismic activity in two areas of the M_S6.1 earthquake in the south Yellow Sea in 1996 and the M_S5.2 earthquake in Fujian in 1997, the potential source zone division is discussed. | Zheng Yuejun Zhang Shimin Cui Xiaofeng Huang Zhongxian | 2006 | Earthquake Research in China2006，20，4： | 0 |
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