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| 1 | The relationship between the thermohaline circulation and climate variability显示文摘The long-term integration with the Global Ocean-Atmosphere-Land System model of the State Key Laboratory of Atmospheric Sciences and Geophysical Fluid Dynamics (LASG), Institute of Atmospheric Physics(IAP), Chinese Academy of Sciences has been used in the investigations on the relationship between the thermohaline circulation and climate variability. The results show that the strength of the North Atlantic Thermohaline circulation (THC) is negatively correlated with the North Atlantic Oscillation (NAO). Based on this kind of relationship, and also the instrument-measured climate record such as air pressure and sea surface temperature, the activity of the thermohaline circulation during the 20th century has been evaluated. The inferred variations of the strength of the THC is that, during two multi-decadal periods of 1867-1903 and 1934-1972, the THC is estimated to have been running stronger, whereas during the two periods of 1904-1933 and 1973-1994, it appears to have been weaker. | ZHOU Tianjun ZHANG Xuehong WANG Shaowu | 2000 | Chinese Science Bulletin2000，45，11： | 13 |
| 2 | miR-145 improves metabolic inflammatory disease through multiple pathways显示文摘Chronic inflammation plays a pivotal role in insulin resistance and type 2 diabetes,yet the mechanisms are not completely understood.Here,we demonstrated that serum LPS levels were significantly higher in newly diagnosed diabetic patients than in normal control.miR-145 level in peripheral blood mononuclear cells decreased in type 2 diabetics.LPS repressed the transcription of miR-143/145 cluster and decreased miR-145 levels.Attenuation of miR-145 activity by anti-miR-145 triggered liver inflammation and increased serum chemokines in C57BL/6 J mice.Conversely,lentivirus-mediated miR-145 overexpression inhibited macrophage infiltration,reduced body weight,and improved glucose metabolism in db/db mice.And miR-145 overexpression markedly reduced plaque size in the aorta in ApoE−/−mice.Both OPG and KLF5 were targets of miR-145.miR-145 repressed cell proliferation and induced apoptosis partially by targeting OPG and KLF5.miR-145 also suppressed NF-κB activation by targeting OPG and KLF5.Our findings provide an association of the environment with the progress of metabolic disorders.Increasing miR-145 may be a new potential therapeutic strategy in preventing and treating metabolic diseases such as type 2 diabetes and atherosclerosis. | Min He Nan Wu Man Cheong Leong Weiwei Zhang Zi Ye Rumei Li Jinyang Huang Zhaoyun Zhang Lianxi Li Xiao Yao Wenbai Zhou Naijia Liu Zhihong Yang Xuehong Dong Yintao Li Lili Chen Qin Li Xuanchun Wang Jie Wen Xiaolong Zhao Bin Lu Yehong Yang Qinghua Wang Renming Hu | 2020 | Journal of Molecular Cell Biology2020，12，2： | 7 |
| 3 | Single-Crystalline In Ga As Nanowires for Room-Temperature High-Performance Near-Infrared Photodetectors显示文摘In Ga As is an important bandgap-variable ternary semiconductor which has wide applications in electronics and optoelectronics. In this work, single-crystal In Ga As nanowires were synthesized by a chemical vapor deposition method.Photoluminescence measurements indicate the In Ga As nanowires have strong light emission in near-infrared region. For the first time, photodetector based on as-grown In Ga As nanowires was also constructed. It shows good light response over a broad spectral range in infrared region with responsivity of 6.5×10~3 AW^(-1) and external quantum efficiency of 5.04×10~5%. This photodetector may have potential applications in integrated optoelectronic devices and systems. | Huang Tan Chao Fan Liang Ma Xuehong Zhang Peng Fan Yankun Yang Wei Hu Hong Zhou Xiujuan Zhuang Xiaoli Zhu Anlian Pan | 2016 | Nano-Micro Letters2016，8，1： | 6 |
| 4 | Impact of the closure of Indonesian seaway on climate: A numerical modeling study显示文摘Using a global OGCM and its relevant coupledocean-atmosphere GCM with the contemporary, 6 MaBPand 14 MaBP oceanic topography, respectively, a series ofnumerical experiments are implemented in order to investi-gate the effect of the north shift of Australian continent onthe tropical oceanic circulation, especially the formation ofthe western Pacific warm pool. The numerical experimentsof the individual OGCM forced by the modern atmosphericcirculation indicate that the closure of Indonesian passageresults in warming in the tropical Pacific Ocean and coolingin the tropical Indian Ocean; furthermore, it also results inchange in source of the Indonesian Through Flow (ITF) wa-ter, e.g. ITF mainly originates from the south Pacific at 14MaBP, but it mainly originates from the north Pacific now.The coupled model shows similar results as the individualOGCM qualitatively. | YU Yongqiang, ZHOU Zuyi & ZHANG Xuehong 1. LASG, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China: 2. Laboratory of Marine Geology, Tongji University, Shanghai 200092 China | 2003 | Chinese Science Bulletin2003，48，S2： | 6 |
| 5 | The coupling procedure of air-sea freshwater exchange in climate system models显示文摘A coupling procedure of air-sea freshwater exchange in climate system models is reported in this note. The first stage of the procedure is to force OGCM to equilibrium under strong restoring surface condition on salinity, then increase the relaxing coefficient and get another steady state. The second stage is to switch the forcing on salinity from the weak restoring condition to the flux condition, and then finish a long-term spinning-up integration. After finishing these OGCM spinning-up stages, the last stage is to couple the OGCM with an active atmosphere, i.e. AGCM. Verification with the Global-Ocean-Atmosphere-Land-System model developed at the State Key Laboratory of Atmospheric Sciences and Geophysical Fluid Dynamics (LASG) shows that the preferred procedure is successful in including the air-sea freshwater exchange process. | Tianjun Zhou Xuehong Zhang Yongqiang Yu | 2001 | Chinese Science Bulletin2001，46，1： | 5 |
| 6 | Online illumination estimation of outdoor scenes based on videos containing no shadow area显示文摘Real-time estimation of outdoor illumination is one of the key issues for ensuring the illumination consistency of augmented reality.In this paper,we propose a novel framework to estimate the dynamic illumination of outdoor scenes based on an online video sequence captured by a fixed camera.All existing approaches are based on two assumptions,i.e.there exist some shadow areas in the scene and the distribution of the skylight is uniform over the sky.Both assumptions greatly simplify the problem of illumination estimation of outdoor scenes,but they also limit the applicability as well as the accuracy of these approaches.This paper presents a new approach that breaks these two hard constraints.It recovers the lighting parameters of outdoor scenes containing no shadow area through solving a constrained linear least squares problem.By representing the skylight as a parameterized model incorporating an occlusion coefficient,the proposed approach can handle the dynamic variation of non-uniform skylight distribution.Experimental results demonstrate the potential of our approach. | XING GuanYu ZHOU XueHong LIU YanLi QIN XueYing PENG QunSheng | 2013 | Science China(Information Sciences)2013，56，3： | 3 |
| 7 | Preparation of hollow fiber membranes from mullite particles with aid of sintering additives显示文摘Porous mullite hollow fiber membranes were prepared with a combined phase-inversion and sintering method,using three sintering additives including yttrium stabilized zirconia(YSZ),small mullite particles(SMP),and titanium oxide(TiO2)to promote the particle sintering.The results indicated that all the three additives could improve the sintering performance of mullite hollow fiber membranes due to the decrease in activation energy of mullite grains.Both YSZ and T i02 could react with mullite grains to generate composite oxides(e.g.,ZrSi04 and Al2Ti05)during sintering,following a reaction-sintering mechanism.Interestingly,the newly generated ZrSiO4 was instable and further decomposed into monoclinic ZrO2 and SiO2 in the sintering process.The decomposition could avoid excessive embedment of composite oxides among mullite grains which have negative impact on mechanical strength of mullite hollow fibers.Overall,the doping of YSZ provided a better promotion effect on the sintering of mullite hollow fiber membranes,where the microstructural and mechanical properties are insensitive to the doping content and sintering temperatures,so it could be used as the candidate for the large-scale preparation of mullite hollow fibers. | Hua LIU Jinyun LIU Zhou HONG Shengxian WANG Xuechao GAO Xuehong GU | 2021 | Journal of Advanced Ceramics2021，10，1： | 3 |
| 8 | A male-ABCD algorithm for hepatocellular carcinoma risk prediction in HBs Ag carriers显示文摘Objective: Hepatocellular carcinoma(HCC) development among hepatitis B surface antigen(HBs Ag) carriers shows gender disparity, influenced by underlying liver diseases that display variations in laboratory tests. We aimed to construct a risk-stratified HCC prediction model for HBs Ag-positive male adults.Methods: HBs Ag-positive males of 35-69 years old(N=6,153) were included from a multi-center populationbased liver cancer screening study. Randomly, three centers were set as training, the other three centers as validation. Within 2 years since initiation, we administrated at least two rounds of HCC screening using Bultrasonography and α-fetoprotein(AFP). We used logistic regression models to determine potential risk factors,built and examined the operating characteristics of a point-based algorithm for HCC risk prediction.Results: With 2 years of follow-up, 302 HCC cases were diagnosed. A male-ABCD algorithm was constructed including participant's age, blood levels of GGT(γ-glutamyl-transpeptidase), counts of platelets, white cells,concentration of DCP(des-γ-carboxy-prothrombin) and AFP, with scores ranging from 0 to 18.3. The area under receiver operating characteristic was 0.91(0.90-0.93), larger than existing models. At 1.5 points of risk score,26.10% of the participants in training cohort and 14.94% in validation cohort were recognized at low risk, with sensitivity of identifying HCC remained 100%. At 2.5 points, 46.51% of the participants in training cohort and 33.68% in validation cohort were recognized at low risk with 99.06% and 97.78% of sensitivity, respectively. At 4.5 points, only 20.86% of participants in training cohort and 23.73% in validation cohort were recognized at high risk,with positive prediction value of 22.85% and 12.35%, respectively.Conclusions: Male-ABCD algorithm identified individual's risk for HCC occurrence within short term for their HCC precision surveillance. | Yuting Wang Minjie Wang He Li Kun Chen Hongmei Zeng Xinyu Bi Zheng Zhu Yuchen Jiao Yong Wang Jian Zhu Hui Zhao Xiang Liu Chunyun Dai Chunsun Fan Can Zhao Deyin Guo Hong Zhao Jianguo Zhou Dongmei Wang Zhiyuan Wu Xinming Zhao Wei Cui Xuehong Zhang Jianqiang Cai Wanqing Chen Chunfeng Qu | 2021 | Chinese Journal of Cancer Research2021，33，3： | 3 |
| 9 | Mercury Distribution and Accumulation in Typical Wetland Ecosystems of Sanjiang Plain,Northeast China显示文摘Total mercury in soil,water,plant,insects,fishes and bird feathers were determined to study mercury distribution and accumulation in typical wetland ecosystems in the Sanjiang Plain,Northeast China.Results show that total mercury concentrations in soils of Deyeuxia angustifolia wetland and Carex lascarpa wetland are 0.046 mg/kg and 0.063 mg/kg,respectively.Total mercury concentration in water bodies is 0.053 μg/L on average.Of four plants studied,total mercury in moss is the highest with the mean of 0.132 mg/kg.Of 10 terrestrial insect species studied,total mercury in centipede(Scolopendra spp.) is the highest with the mean of 0.515 mg/kg while total mercury in grasshopper(Oxya spp.) bodies is the lowest.Total mercury concentrations in the herbivorous,omnivorous and predatory insects are 10.18 ng/g,16.47 ng/g and 213.35 ng/g on average,respectively.Total mercury concentrations of the adult feather(549.88 ± 63.04 ng/g),nestling feather(55.15 ± 23.53 ng/g),and eggshell(22.05 ± 5.96 ng/g) of the Grey heron(Ardea cinerea) are higher than those of the Great egret(Egretta alba)(adult feather:446.57 ± 90.89 ng/g;nestling feather:32.99 ± 17.15 ng/g;eggshell:21.02 ± 3.17 ng/g) in the wetlands of the Sanjiang Plain.The bioconcentration factors decrease in the order of piscivorous fish muscle > omnivorous fish muscle > herbivorous fish > insect. | WANG Qiang ZHANG Zhongsheng ZHOU Xuehong LU Xianguo | 2013 | Chinese Geographical Science2013，23，1： | 2 |
| 10 | Sustained delivery of rhMG53 promotes diabetic wound healing and hair follicle development显示文摘MG53 is an essential component of the cell membrane repair machinery,participating in the healing of dermal wounds.Here we develop a novel delivery system using recombinant human MG53(rhMG53)protein and a reactive oxygen species(ROS)-scavenging gel to treat diabetic wounds.Mice with ablation of MG53 display defective hair follicle structure,and topical application of rhMG53 can promote hair growth in the mg53/mice.Cell lineage tracing studies reveal a physiological function of MG53 in modulating the proliferation of hair follicle stem cells(HFSCs).We find that rhMG53 protects HFSCs from oxidative stress-induced apoptosis and stimulates differentiation of HSFCs into keratinocytes.The cytoprotective function of MG53 is mediated by STATs and MAPK signaling in HFSCs.The thermosensitive ROS-scavenging gel encapsulated with rhMG53 allows for sustained release of rhMG53 and promotes healing of chronic cutaneous wounds and hair follicle development in the db/db mice.These findings support the potential therapeutic value of using rhMG53 in combination with ROS-scavenging gel to treat diabetic wounds. | Hong Niu Haichang Li Ya Guan Xin Zhou Zhongguang Li Serana Li Zhao Peng Chen Tao Tan Hua Zhu Valerie Bergdall Xuehong Xu Jianjie Ma Jianjun Guan | 2022 | Bioactive Materials2022，7，12： | 2 |
| 11 | A review on the mechanical methods for evaluating coating adhesion显示文摘 | Zhaoxiang Chen Kun Zhou Xuehong Lu Yee Cheong Lam | 2014 | Acta Mechanica2014，，2： | 1 |
| 12 | Girth-10 LDPC codes based on 3-D cyclic lattices显示文摘 | Zhang Fan Mao Xuehong Zhou Wuyang | 2008 | IEEE Trans on Vehicular Technology2008，57，2： | 1 |
| 13 | Renewal Design of Marketplace Culture Spaces in Traditional Blocks Based on Catalyst Theory: A Case Study of Pengzhen Town in Shuangliu District of Chengdu显示文摘In this study, three kinds of spaces with different marketplace atmospheres, namely, the tea-drinking space, the commercial space and the courtyard space, are created with the aid of the marketplace culture characteristics of the local blocks in Pengzhen Town and the catalyst theory, so as to achieve the purpose of activating the traditional blocks in Pengzhen Town. The design takes the marketplace culture as the entry point and the most vigorous points as the catalyst points to create a living space with strong marketplace flavor, thereby activating the economic and social activities of the traditional block and promotes the sustainable renewal of the cultural space. | NIE Kangcai ZHOU Xuehong | 2019 | Journal of Landscape Research2019，11，4： | 1 |
| 14 | Fundamental framework and experiments of the Third Generation of 1AP/LASG WoAd Ocean General Circulation Model显示文摘 | Jin Xiangze Zhang Xuehong Zhou Tianjun | 1999 | Advances in Atmospheric Sciences1999，16，： | 1 |
| 15 | Simultaneous red-green-blue electroluminescent enhancement directed by surface plasmonic "far-field" of facile gold nanospheres显示文摘基于表面血浆回声的远地的效果,由灵巧的综合金 nanospheres 的同时的 red-green-blue electroluminescence 改进在这个工作被认识到,它将困难、复杂用选择波长的局部性的表面血浆回声到达。远地的效果能同时提高的 plasmonic 在白轻范围的整个排放区域,因为到红排放的从蓝色的提高的区域大部分被重叠。由做嵌入在的金 nanospheres 一 poly (3,4乙烯 dioxythiophene ):聚苯乙烯酸性硫酸基的酸( PEDOT : PSS )层,收益改进与60%的最好的提高比率和国际 de LEclairage ( CIE )坐标是的委员会在超过95%设备被完成在稳定近似( 0.33 , 0.36 )。plasmonic 远地的效果在 picomolar 大小要求 Au NP 的极端低的工作集中,并且在电子进程并且轻散布上显示出小否定效果,它在认识到在新窗户中射出 diodes.Open | Xiaoyan Wu Yiqi Zhuang Zhongtao Feng Xuehong Zhou Yuzhao Yang Linlin Liu Zengqi Xie Xudong Chen Yuguang Ma | 2018 | Nano Research2018，11，1： | 1 |
| 16 | Girth - 10 LDPC codes based on 3-D cyclic lattices 显示文摘 | Zhang Fan Mao Xuehong Zhou Wuyang | 2008 | IEEE Trans on Vehicular Technology2008，57，2： | 1 |
| 17 | Helium extraction from natural gas using DD3R zeolite membranes显示文摘Helium(He)is commercially produced from natural gas by low-temperature condensation.The process is energy extensive because of the extremely low He concentration(<0.3%)and the operation at cryogenic temperature.Herein we demonstrated DD3R zeolite membrane was efficient to extract He from natural gas at atmosphere temperature.The membrane performance was evaluated in terms of temperature,pressure and molar fractions.The overall membrane performance was dominated by the diffusivity selectivity.The single He permeance and ideal He/CH_(4) selectivity were 5.8×10^(-9)mol·m^(-2)·s^(-1)·Pa^(-1)and 79 under a feed pressure of 1.3 MPa.Even though He concentration was as low as 0.22%,the He permeance and He/CH_(4) mixture selectivity were 3.0×10^(-9)mol·m^(-2)·s^(-1)·Pa^(-1)and 44 at 0.7 MPa.During the longterm operation(~130 h)the membrane performance was stable even the feed mixture containing3.6%ethane as contaminations.The results approved the feasibility of DD3R zeolite membranes for He extraction from natural gas. | Ping Zhang Chao Gong Tao Zhou Peng Du Jieyu Song Mengyang Shi Xuerui Wang Xuehong Gu | 2022 | Chinese Journal of Chemical Engineering2022，35，9： | 1 |
| 18 | Stresses of orthotropic laminated beams subjected to high temperature and mechanical load显示文摘Thermo-elastic analysis of simply-supported orthotropic laminated beams subjected to high temperature and mechanical load is presented on the basis of the exact two-dimensional thermoelasticity theory.The beam is composed of several orthotropic layers,each with temperaturedependent material properties.The governing equation for each layer is analytically solved using the state space method.The displacement and stress solutions of the beam are obtained using the transfer-matrix method.A numerical example is included to study the effects of temperature on the mechanical responses of a sandwich beam.The results reveal two main effects of temperature:(i)inducing deformations and stresses by itself;(ii)affecting the deformations and stresses induced by the mechanical load. | Zhong Zhang Ding Zhou Xiuli Xu Xuehong Li | 2019 | Theoretical & Applied Mechanics Letters2019，9，5： | 1 |
| 19 | Desalination of seawater ion complexes by MFI-type zeolite membranes: Temperature and long term stability显示文摘 | Bo Zhu Zhou Hong Nicholas Milne Cara M. Doherty Linda Zou Y.S. Lin Anita J. Hill Xuehong Gu Mikel Duke | 2014 | Journal of Membrane Science2014，，： | 1 |
| 20 | Research on Remote Video Monitoring System Used for Numerical Control Machine Tools Based on Embedded Technology显示文摘This paper designed an embedded video monitoring system using DSP (Digital Signal Processing ) and ARM (Ad- vanced RISC Machine).This system is an important part of self-service operation of numerical control machine tools,At first the analog input signals from the CCD(Charge Coupled Device) camera are transformed into digital signals,and then output to the DSP system,where the video sequence is encoded according to the new generation image compressing standard called H.264.The code will be transmitted to the ARM system through xBus,and then be packed in the ARM system and transmitted to the client port through the gateway.Web technology,embedded technology and image compressing as well as coding technology are integrated in the system,which can be widely used in self-service operation of numerical control machine tools and intelligent robot control areas. | LIU Quan QU Xuehong ZHOU Henglin LONG Yihong (School of Information Engineering,Wuhan University of Technology,Wuhan 430070,China | 2006 | 武汉理工大学学报2006，28，S2： | 1 |
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