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| 1 | Urban Water Resource Utilization Efficiency in China显示文摘The efficient use of water resources directly affects environmental, social, and economic development; therefore, it has a significant impact on urban populations. A slacks-based measure for data envelopment analysis(SBM-DEA) has been widely used in energy efficiency and environmental efficiency analyses in recent years. Based on this model, data from 316 cities were examined and a category method was employed involving three different sorting techniques to empirically evaluate the efficiency of urban water resource utilization in China between 2000 and 2012. The overall efficiency(OE) of urban water resource utilization in China was initially low, but has improved over the past decade. The scale efficiency(SE) was higher than the pure technological efficiency(PTE); PTE is a major determining factor of OE, and has had an increasingly significant effect. The efficiency of water resource utilization varied according to the region, urban scale, and economic function. The OE score for the eastern China was higher than for the rest of the region, and the OE score for the western China was higher than for the central China. The OE score for urban water resource utilization has improved with urban expansion, except in the case of small cities. The SE showed an inverted ′U-shaped′ trend with increasing urban expansion. The OE of urban water utilization in comprehensive functional cities was greater than in economic specialization cities, and was greater in heavy industry specialization cities than in other specialization cities. This study contributes to the field of urban water resource management by examining variations in efficiency with urban scale. | SHI Tiange ZHANG Xiaolei DU Hongru SHI Hui | 2015 | Chinese Geographical Science2015，25，6： | 12 |
| 2 | Terminal sliding mode control based on super-twisting algorithm显示文摘An improved non-singular terminal sliding mode control based on the super-twisting algorithm is proposed for a class of second-order uncertain nonlinear systems. This method can effectively avoid the singularity problem and obviously reduce the chattering phenomenon. The stability of the proposed procedure is proven to be finite-time convergence using the Lyapunov theory against uncertain unmodeled dynamic and external disturbances.An example is given to show the proposed improved non-singular terminal sliding mode control(SMC) law effectively. | Zhanshan Zhao Hongru Gu Jing Zhang Gang Ding | 2017 | Journal of Systems Engineering and Electronics2017，28，1： | 8 |
| 3 | Spatial Effect of Mineral Resources Exploitation on Urbanization:A Case Study of Tarim River Basin,Xinjiang,China显示文摘Mineral resources exploitation significantly affects the spatial structure and evolutive trend of urbanization in arid areas.In this study,the spatial autocorrelation method and the spatial computation model were used to investigate the spatial impacts of mineral resources excavation and processing on comprehensive level of urbanization in the Tarim River Basin,Xinjiang,China for the years of 2000,2006 and 2008.The results are as follows:1)There was a spatial correlation of the development of mineral resources industry and the comprehensive level of urbanization in 2006 and 2008,with the spatial concentration trend rising significantly in 2006 and decreasing in 2008.2)The patterns of local spatial concentration of mineral resources industry and of the comprehensive level of urbanization were relatively stable,and the two patterns showed signs of spatial correlationship.The higher was the degree of the concentration of mineral resources industry,the stronger was its impact on the spatial clustering of urbanization.3)In 2000, mineral resources excavation and processing had a significant positive impact on the comprehensive level of urbanization in the region but not in its adjacent regions.However,in 2008,mineral resources excavation and processing significantly raised the comprehensive level of urbanization not only in the region but also in its neighboring regions.This research demonstrates that the development of mineral resources industry can strongly affect the trends and spatial patterns of urbanization. | LI Xuemei ZHANG Xiaolei DU Hongru CHU Shaolin | 2012 | Chinese Geographical Science2012，22，5： | 5 |
| 4 | LIN28 coordinately promotes nucleolar/ribosomal functions and represses the 2C-like transcriptional program in pluripotent stem cells显示文摘LIN28 is an RNA binding protein with important roles in early embryo development,stem cell differentiation/re-programming,tumorigenesis and metabolism.Previous studies have focused mainly on its role in the cytosol where it interacts with Let-7 microRNA precursors or mRNAs,and few have addressed LIN28's role within the nucleus.Here,we show that LIN28 displays dynamic temporal and spatial expression during murine embryo development.Maternal LIN28 expression drops upon exit from the 2-cell stage,and zygotic LIN28 protein is induced at the forming nucleolus during 4-cell to blas-tocyst stage development,to become dominantly expressed in the cytosol after implantation.In cultured pluripotent stem cells(PSCs),loss of LIN28 led to nucleolar stress and activation of a 2-cell/4-cell-like transcriptional program characterized by the expression of endogenous retrovirus genes.Mechanistically,LIN28 binds to small nucleolar RNAs and rRNA to maintain nucleolar integrity,and its loss leads to nucleolar phase separation defects,ribosomal stress and activation of P53 which in turn binds to and activates 2C transcription factor Dux.LIN28 also resides in a complex containing the nucleolar factor Nucleolin(NCL)and the transcrip-tional repressor TRIM28,and LIN28 loss leads to reduced occupancy of the NCL/TRIM28 complex on the Dux and rDNA loci,and thus de-repressed Dux and reduced rRNA expression.Lin28 knockout cells with nucleolar stress are more likely to assume a slowly cycling,translationally inert and anabolically inactive state,which is a part of previously unappreciated 2C-like transcriptional program.These findings elucidate novel roles for nucleolar LIN28 in PSCs,and a new mechanism linking 2C program and nucleolar functions in PSCs and early embryo development. | Zhen Sun Hua Yu Jing Zhao Tianyu Tan Hongru Pan Yuqing Zhu Lang Chen Cheng Zhang Li Zhang Anhua Lei Yuyan Xu Xianju Bi Xin Huang Bo Gao Longfei Wang Cristina Correia Ming Chen Qiming Sun Yu Feng Li Shen Hao Wu Jianlong Wang Xiaohua Shen George Q.Daley Hu Li Jin Zhang | 2022 | Protein & Cell2022，13，7： | 4 |
| 5 | A super pan-genomic landscape of rice显示文摘Pan-genomes from large natural populations can capture genetic diversity and reveal genomic complexity.Using de novo longread assembly,we generated a graph-based super pan-genome of rice consisting of a 251-accession panel comprising both cultivated and wild species of Asian and African rice.Our pan-genome reveals extensive structural variations(SVs)and gene presence/absence variations.Additionally,our pan-genome enables the accurate identification of nucleotide-binding leucine-rich repeat genes and characterization of their inter-and intraspecific diversity.Moreover,we uncovered grain weight-associated SVs which specify traits by affecting the expression of their nearby genes.We characterized genetic variants associated with submergence tolerance,seed shattering and plant architecture and found independent selection for a common set of genes that drove adaptation and domestication in Asian and African rice.This super pan-genome facilitates pinpointing of lineage-specific haplotypes for trait-associated genes and provides insights into the evolutionary events that have shaped the genomic architecture of various rice species. | Lianguang Shang Xiaoxia Li Huiying He Qiaoling Yuan Yanni Song Zhaoran Wei Hai Lin Min Hu Fengli Zhao Chao Zhang Yuhua Li Hongsheng Gao Tianyi Wang Xiangpei Liu Hong Zhang Ya Zhang Shuaimin Cao Xiaoman Yu Bintao Zhang Yong Zhang Yiqing Tan Mao Qin Cheng Ai Yingxue Yang Bin Zhang Zhiqiang Hu Hongru Wang Yang Lv Yuexing Wang Jie Ma Quan Wang Hongwei Lu Zhe Wu Shanlin Liu Zongyi Sun Hongliang Zhang Longbiao Guo Zichao Li Yongfeng Zhou Jiayang Li Zuofeng Zhu Guosheng Xiong Jue Ruan Qian Qian | 2022 | Cell Research2022，32，10： | 3 |
| 6 | Spatial difference features and organization optimization of cities and towns in Tarim River Basin显示文摘This paper analyzes the urban spatial structure of Tarim River Basin from the perspectives of urbanization, urban density, grading scales and spatial evolution patterns, using geographical theories and methods, such as fractal theory, principle component analysis, urbanization imbalance index, urban scale imbalance indicator, and urban spatial interaction. The results show that the urban spatial structure displays balanced distribution in the overall pattern, while an imbalanced distribution in each region. The development of town pattern tends to be gathering to the central towns in the oasis of Tarim River Basin and a development axis has begun to form along the southern Xinjiang railway. Based on the division of urban hinterland, and the development characteristics of oasis economy, this paper puts forward an urban spatial organization model. This model uses 'breakpoint model' and divides Tarim River Basin into five urban clusters: Korla urban cluster, Kuqa urban cluster, Aksu urban cluster, Kashgar urban cluster and Hotan urban cluster. As a conclusion, this article puts forward an overall framework of urban spatial organization in Tarim River Basin: 'one axis, double core, and five groups'. | ChangLong SUN XiaoLei ZHANG Nuo JIN HongRu DU WenWen MA | 2010 | Journal of Arid Land2010，2，1： | 3 |
| 7 | Co-adaptation between modern oasis urbanization and water resources exploitation:A case of Urumqi显示文摘水资源利用在在干旱地区的整个绿洲都市化期间总是是很重要的,与在矛盾和协作之间的城市的开发适应。作为一个盒子,水利用的合作改编和城市的生长拿 Urumqi 城市被在水供应和绿洲城市之间的相互作用模仿“ s 阐述人口,经济和环境。在不同都市化阶段,合作改编能不同地被代表,它能被五个阶段总结:基本协作,膨胀协作,膨胀矛盾,适应矛盾,和适应协作。水消费的费用,水使用和效率的比例是主要影响因素帮助合作改编。 | DU Hongru ZHANG Xiaolei WANG Bin | 2006 | Chinese Science Bulletin2006，51，A01： | 3 |
| 8 | Comprehensive test stand for high-intensity cyclotron development显示文摘A comprehensive test stand for high-intensity cyclotron development,a 10 MeV 430 μA cyclotron,has been successfully constructed at China Institute of Atomic Energy (CIAE) for the experimental verification of the viability of a 100 MeV high-intensity cyclotron (CYCIAE-100) being constructed at CIAE.The verification includes the overall design technology,detail design and engineering technology for the crucial parts of the machine,e.g.main magnet and beam diagnostics.It will also pave the way for future enhancement of the beam intensity.The test stand consists of a H-ion source,axial injection system,central region,main magnet and coil,RF resonator,stripping extraction,and auxiliary systems,which include the RF power amplifier,high voltage and DC power supplies,electric apparatus,beam diagnostics,control,vacuum,water cooling,pneumatic system,and safety interlock.This paper presents the work regarding the design and sub-system development of the test sand,and the results of the beam commissioning of the machine. | ZHANG TianJue LI ZhenGuo CHU ChengJie XING JianSheng GUAN FengPing ZHONG JunQing JI Bin GE Tao YIN ZhiGuo HOU ShiGang PAN GaoFeng YAO HongJuan LU YinLong WANG ZhenHui WU LongCheng LIN Jun JIA XianLu WEI SuMin WEN LiPeng WANG Feng XIA Le CAI HongRu XIE HuaiDong CHEN RongFan ZHANG Yan ZHANG SuPing LIU GengShou ZOU Jian AN ShiZhong YANG JianJun BI YuanJie YANG Fang | 2011 | Chinese Science Bulletin2011，56，3： | 3 |
| 9 | Thermal annealing synthesis of double-shell truncated octahedral Pt-Ni alloys for oxygen reduction reaction of polymer electrolyte membrane fuel cells显示文摘Shape-controlled Pt-Ni alloys usually offer an exceptional electrocatalytic activity toward the oxygen reduction reaction(ORR)of polymer electrolyte membrane fuel ceils(PEMFCs),whose tricks lie in welldesigned structures and surface morphologies.In this paper,a novel synthesis of truncated octahedral PtNi_(3.5) alloy catalysts that consist of homogeneous Pt-Ni alloy cores enclosed by NiO-Pt double shells through thermally annealing defective heterogeneous PtNi35 alloys is reported.By tracking the evolution of both compositions and morphologies,the outward segregation of both PtOv and NiO are first observed in Pt-Ni alloys.It is speculated that the diffusion of low-coordination atoms results in the formation of an energetically favorable truncated octahedron while the outward segregation of oxides leads to the formation of NiO-Pt double shells.It is very attractive that after gently removing the NiO outer shell,the dealloyed truncated octahedral core-shell structure demonstrates a greatly enhanced ORR activity.The asobtained truncated octahedral Pt_(2.1)Ni core-shell alloy presents a 3.4-folds mass-specific activity of that for unannealed sample,and its activity preserves 45.4%after 30000 potential cycles of accelerated degradation test(ADT).The peak power density of the dealloyed truncated octahedral Pt2jNi core-shell alloy catalyst based membrane electrolyte assembly(MEA)reaches 679.8 mW/cm^(2),increased by 138.4 mW/cm^(2) relative to that based on commercial Pt/C. | Xiashuang LUO Yangge GUO Hongru ZHOU Huan REN Shuiyun SHEN Guanghua WEI Junliang ZHANG | 2020 | Frontiers in Energy2020，14，4： | 2 |
| 10 | iTRAQ-Based Proteomics Investigation of Critical Response Proteins in Embryo and Coleoptile During Rice Anaerobic Germination显示文摘Direct-seeding of rice has become popular in recent years due to its low cost and convenience,however,hypoxic condition limits seedling establishment.In this study,weedy rice WR04-6 with high germination ability under anaerobic conditions was used as a gene donor,and we successfully improved the seedling establishment rate of rice cultivar Qishanzhan(QSZ)based on selection of a new rice line R42 from the recombinant inbred line population.R42 inherited high anaerobic germination(AG)ability,and was used for isobaric tags for relative and absolute quantitation(iTRAQ)-based comparative proteomic studies with QSZ to further explore the molecular mechanism of AG.A total of 719 differentially abundant proteins(DAPs)were shared by R42 and QSZ responded to AG,and thus defined as common response DAPs.A total of 300 DAPs that responded to AG were only identified from R42,which were defined as tolerance-specific DAPs.The common response and tolerance-specific DAPs had similar biochemical reaction processes and metabolic pathways in response to anoxic stress,however,they involved different proteins.The tolerance-specific DAPs were involved in amino acid metabolism,starch and sucrose metabolism,tricarboxylic acid cycle pathway,ethylene synthesis pathway,cell wall-associated proteins and activity of active oxygen scavenging enzyme.The in silico protein-protein interactions for the top 60 DAPs indicated that tolerance-specific DAPs had relatively independent protein interaction networks in response to an anoxic environment compared with common response DAPs.The results of physiological indicators showed thatα-amylase and superoxide dismutase activities of R42 were significantly increased under anoxic conditions compared with aerobic conditions.Multiple lines of evidence from western blot,physiological analysis and quantitatDirect seeding of rice has become popular in recent years due to its low cost and convenience,however,hypoxic conditions can limit seedling establishment.In the present study,weedy rice WR04-6 with high germination ability in anaerobic conditions was used as the gene donor and successfully improved the seedling establishment rate of rice cultivar Qishanzhan(QSZ)based on selection of a new rice line R42 from the recombinant inbred line(RIL)population.R42 inherited the had high anaerobic germination(AG)ability,which was used for the isobaric tags for relative and absolute quantitation(iTRAQ)based comparative proteomic studies with QSZ to further explore the molecular mechanism of AG.A total of 719 differentially abundant proteins(DAPs)shared by R42 and QSZ responded to AG and were thus defined as common response DAPs.A total of 300 DAPs that responded to AG were only identified from R42,which were defined as tolerance-specific DAPs.The common response and tolerance-specific DAPs had similar biochemical reaction processes and metabolic pathways in response to anoxic stress,however they involved different proteins.The 300 tolerance-specific DAPs were involved in amino acid metabolism,starch and sucrose metabolism,TCA cycle pathways,ethylene synthesis pathway,cell wall-associated proteins and activity of active oxygen scavenging enzyme.The in silico protein-protein interactions for the top 60 DAPs indicated that tolerance-specific DAPs had relatively independent protein interaction networks in response to an anoxic environment compared with common response DAPs.The results of physiological indicators showed thatα-amylase and SOD activities of R42 were significantly increased under anoxic conditions compared with aerobic conditions.Multiple lines of evidence from western blot,physiological analyses and real-time PCR jointly supported the reliability of proteomics data.In summary,our findings deepened the understanding of the molecular mechanism for the rice response to AG.ive real-time PCR jointly supported the reliability of proteomics data.In summary,our findings deepened the understanding of the molecular mechanism for the rice response to AG. | Zhang Guangchen Liu Zimeng Liu Yoxihong Kuya Noriyuki HuAYuchen Shi Hongru Zhao Weilin Han Yuqing Yamamoto Toshio Chen Wenfu Sun Jian | 2021 | Rice science2021，28，4： | 2 |
| 11 | New Supercritical Fluid Extraction Treatment Method for Determination of Tripterine in Tripterygium wilfordii Hook. F显示文摘 | Hongru Li Shufen Li Yu Zhang Hongquan Duan | 2008 | Journal of Liquid Chromatography & Related Technologies2008，，10： | 1 |
| 12 | Effects of levodopa on dopaminergic neurons and induced dyskinesia A radio-imaging study显示文摘BACKGROUND: Radio-imaging has been used in neurological diagnosis,in particular for extrapyramidal disease.Moreover,it has been extensively utilized for early diagnosis of Parkinson’s disease (PD) patients and in animal studies.However,it has rarely been utilized to assess drug-induced side effects in PD.OBJECTIVE: To investigate changes in dopamine transporter expression in a rat model of PD through the use of radio-imaging taking 99mTc-TRODAT-1 as an imaging agent,and to explore the effect of levodopa (L-dopa) on dopaminergic neurons and the possible mechanisms of dyskinesia induction.DESIGN,TIME AND SETTING: A randomized,controlled,animal study was performed at the Laboratory of Department of Nuclear Medicine,Soochow University from April 2006 to June 2007.MATERIALS: 6-hydroxydopamine was purchased from Sigma,USA and L-dopa was purchased from Shanghai Fuda Pharmaceutical,China.99mTcO4-fresh elutriant was provided by the Department of Nuclear Medicine,First Hospital Affiliated to Soochow University.TRODAT-1 image kit was provided by Jiangsu Atomic Energy Research Establishment,China.The SN-695B radioimmunoassay gamma counter was purchased from Shanghai Hesuo Rihuan Photoelectric Instrument,China.The AZ-CA256eZ-Scope portable γ camera was purchased from Anzai Medical,Japan.METHODS: A total of 34 healthy,male,Sprague Dawley rats were selected.Thirty were used to establish a PD model by injecting 6-hydroxydopamine into the right medial forebrain bundle,and four were injected with normal saline and served as the sham-surgery group.At the end of 4 weeks,21 successful PD models were selected and randomly assigned to the L-dopa (n = 15,20 mg/kg per day),model (n = 6,normal saline),and sham-surgery (n = 4,no treatment) groups.After 1 month of treatment,involuntary movement was evaluated twice weekly in each rat.A total of 0.2 mL 99mTc-TRODAT-1 was injected into the tail vein 2 days following drug termination,and images of dopamine transporters were acquired 2 hours later.The rats were sacrificed and the ratios of specific radioactivity uptake were calculated.MAIN OUTCOME MEASURES: Manifestations of abnormal involuntary movement (AIM) were observed and total AIM scores were calculated.Images of dopamine transporters were acquired using an eZ-Scope portable γ camera,and radioactive γ quantification of 99mTc-TRODAT-1 in the rat brains was assayed.The ratios of the left and right corpora striata were determined.The number and function of dopamine transporters was evaluated according to specific radioactivity uptake ratio (R) from the left and right corpora striata.RESULTS: Of 15 PD rats,nine exhibited AIM following L-dopa treatment: five scored > 20,i.e.,severe grade,four scored 8–16,mild grade,and the remaining exhibited normal behavior.There were no differences in specific radioactivity uptake of dopamine transporter between the left and right corpora striata in the sham-surgery rats,and the images were clear and symmetrically distributed.Specific radioactivity uptake of the normal side (left) was significantly greater than the lesioned side (right) in the model group rats (P < 0.01),and the R value was significantly increased compared with the sham-surgery group (P < 0.01).The radio-ligand accumulation in the right corpus striatum was sparse.In the L-dopa group,specific radioactivity uptake was significantly decreased in the lesioned (right) side of the AIM rats,and the R value was increased compared with the model group (P < 0.05).The amount of radio-ligand in the right corpus striatum was diminished.The R value was significantly reduced in the non-AIM rats compared with the AIM rats (P < 0.05),and specific radioactivity uptake was significantly increased in the lesioned (right) side compared with the normal side (P < 0.05).Moreover,radio-ligand accumulation was observed in the right corpus striatum,and differences in radio-ligand accumulation between the two sides were reduced.CONCLUSION: Following L-dopa treatment,the number and function of dopamine transporter in some PD rats were reduced.L-dopa was shown to be toxic to dopaminergic neurons and induced dyskinesia. | Xiuying Cai Yan Kong Hongru Zhao Bin Zhang Chunfeng Liu | 2010 | Neural Regeneration Research2010，5，2： | 1 |
| 13 | Dynamic Analysis of Train-Bridge System and Its Application in Steel Girder Reinforcement 显示文摘 | XIA He ROECK G D ZHANG Hongru | 2001 | Computers :Structures2001，79，2021： | 1 |
| 14 | Bamboo pyrolysis using TG-FTIR and a lab-scale reactor: Analysis of pyrolysis behavior, product properties, and carbon and energy yields显示文摘 | Chen Dengyu Liu Dong Zhang Hongru | 2015 | Fuel2015，148，15： | 1 |
| 15 | Knowledge Reduction Based on the Equivalence Relations Defined on Attribute set and its Power Set显示文摘 | Wei Ling Li Hongru Zhang Wenxiu | 2007 | Information Sciences2007，177，15： | 1 |
| 16 | Excited state intramolecular proton transfer fluorescence emission of o-hydroxyphenyl-triazine derivatives显示文摘o-hydroxyphenyl-triazine derivatives with formyl substituents were surveyed for the excited state intramolecular proton transfer (ESIPT).The occurrence of ESIPT was confirmed by well-separated emission bands for the derivatives.A low energy change from enol to keto in the excited state explains ESIPT for the derivatives. | LI HaiLi LI HongRu YANG Long XU XiaoFang ZHANG ShengTao GAO Fang | 2011 | Chinese Science Bulletin2011，56，14： | 1 |
| 17 | Path coeffi-cient and cluster analyses of yield and morphological traits inPennisetum purpureum显示文摘 | Zhang Xia Gu Hongru Ding Chenglong | 2010 | Tropical Grasslands2010，44，： | 1 |
| 18 | Interpretation of Healthy Diet Campaign in Healthy China Initiative 2019–2030显示文摘Summary With the continuous development of the economy and agricultural modernization in the past three decades,nutritional deficiency issues in the Chinese population have been gradually improving.However,new nutritional and health challenges have emerged.Overweight and obesity,diabetes,cardiovascular diseases,and other chronic diseases have increasingly become major disease burden.In view of the problems above,the State Council released the Healthy China Initiative 2019-2030 focusing on 15 special campaigns and the Healthy Diet Campaign(HDC)as the second campaign. | Liusen Wang Huijun Wang Zhihong Wang Hongru Jiang Weiyi Li Shaoshunzi Wang Lixin Hao Bing Zhang Gangqiang Ding | 2021 | China CDC weekly2021，3，16： | 1 |
| 19 | Protective effect of Sheng-Nao-Kang decoction on focal cerebral ischemia-reperfusion injury in rats显示文摘 | Lin Chen Ye Zhao Tianlong Zhang Xuan Dang Renming Xie Zhenzhi Li Yang Li Yuli Li Wenna Zhao Hongru Song | 2014 | Journal of Ethnopharmacology2014，，： | 1 |
| 20 | Event-based performance guaranteed tracking control for constrained nonlinear system via adaptive dynamic programming method显示文摘An optimal tracking control problem for a class of nonlinear systems with guaranteed performance and asymmetric input constraints is discussed in this paper.The control policy is implemented by adaptive dynamic programming(ADP)algorithm under two event-based triggering mechanisms.It is often challenging to design an optimal control law due to the system deviation caused by asymmetric input constraints.First,a prescribed performance control technique is employed to guarantee the tracking errors within predetermined boundaries.Subsequently,considering the asymmetric input constraints,a discounted non-quadratic cost function is introduced.Moreover,in order to reduce controller updates,an event-triggered control law is developed for ADP algorithm.After that,to further simplify the complexity of controller design,this work is extended to a self-triggered case for relaxing the need for continuous signal monitoring by hardware devices.By employing the Lyapunov method,the uniform ultimate boundedness of all signals is proved to be guaranteed.Finally,a simulation example on a mass–spring–damper system subject to asymmetric input constraints is provided to validate the effectiveness of the proposed control scheme. | Xingyi Zhang Zijie Guo Hongru Ren Hongyi Li | 2023 | Journal of Automation and Intelligence2023，2，4： | 0 |
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