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| 1 | Evaluation of three tracers for labeling distal cerebrospinal fluidcontacting neurons显示文摘It has been reported that distal cerebrospinal fluidcontacting neurons(dCSF-CNs)can be detected by immunohistochemical assay using cholera toxin subunit B-conjugated horseradish peroxidase(CBHRP).In the present study,another two methods with CB alone or CB-conjugated FITC(CB-FITC)were used,and the results from the three methods were compared.Adult Sprague-Dawley rats were randomly divided into three groups with CB-HRP,CB or CB-FITC.Tracers were diluted to 30%in artificial cerebrospinal fluid and injected separately(in a volume of 3μL)into the lateral ventricle.Animals from the CB-HRP and CB groups were perfused 48 h after surgery while animals from the CB-FITC group were perfused 1,3,6,12,24 or 48 h after surgery.The brain was sectioned(40μm)for immunofluorescence and five sections with positive neurons were selected from each rat for neuron counting.Three clusters of positive neurons in a'Y-like'distribution were detected ventral to the cerebral aqueduct of rats from the three groups.No significant difference was observed among the quantitative data.In the CB-FITC group,stable staining was detected even at 6 h after injection.Taken together,lateral ventricle injection of CB/CB-FITC is a useful method for labeling dCSFCNs in rats.The CB-FITC method makes dCSF-CNs labeling much simpler and more convenient. | Fang Zhou Jiayou Wang Hongxing Zhang He Liu Guangping Zhao Cuihua Zu Xiaoxing Lu Licai Zhang | 2013 | Neuroscience Bulletin2013，29，5： | 7 |
| 2 | Fly ash-based geopolymer as a novel photocatalyst for degradation of dye from wastewater显示文摘The geopolymer synthesized by alkali-activated fly ash was firstly used as a novel photocatalyst for degradation of methylene blue(MB) dye from wastewater.The geopolymer is composed of nanoparticulates with an average particle size of about 50 nm.More than 90%of pore volume in the fly ash-based geopolymer predominately centralized on the pore size in the range of 17-700 nm.The degradation efficiency of MB dye by fly ash-based geopolymer catalyst was up to 92.79%under UV irradiation due to the synergistic effect of adsorption and semiconductor photocatalysis.The pseudo-first-order and pseudo-second-order rate equations as well as intra-particle diffusion rate equation were employed to correlate analysis for the adsorption kinetics of MB dye.The experimental data agreed well with pseudo-second-order rate equation in both cases of with UV and without UV irradiations.The intra-particle diffusion process is not the rate determining step.The photocatalytic degradation of MB dye in solution obeys third-order reaction kinetics. | Yaojun Zhang Licai Liu | 2013 | Particuology2013，11，3： | 5 |
| 3 | Application of Pore Evolution and Fracture Development Coupled Models in the Prediction of Reservoir 'Sweet Spots' in Tight Sandstones显示文摘<正>The Chang-6~3 reservoir in the Huaqing area has widely developed tight sandstone reservoirs characterized by'thick sand layers,but not rich in oil',and it is thus necessary to further study its oil and gas enrichment law.This study builds porosity and fracture development | ZHANG Linyan ZHUO Xizhun MA Licheng CHEN Xiaoshuai SONG Licai ZHOU Xingui | 2015 | Acta Geologica Sinica(English Edition)2015，89，3： | 3 |
| 4 | Applying HOSVD to Alleviate the Sparsity Problem in Context-aware Recommender Systems显示文摘 | WANG Licai | 2013 | Chinese Journal of Electronics2013，22，4： | 2 |
| 5 | Factors controlling geochemical and mineralogical compositions of coals preserved within marine carbonate successions: A case study from the Heshan Coalfield, southern China显示文摘 | Shifeng Dai Weiguo Zhang Vladimir V. Seredin Colin R. Ward James C. Hower Weijiao Song Xibo Wang Xiao Li Lixin Zhao Huan Kang Licai Zheng Peipei Wang Dao Zhou | 2013 | International Journal of Coal Geology2013，，： | 2 |
| 6 | The effect of differential temperatures on the latent heat in the nucleation of CdSe quantum dots显示文摘This work studied the effect of differential temperatures on the latent heat in the nucleation of CdSe quantum dots(QDs).The result showed that,by the formula of phase change,with increasing the reaction temperature,the latent heat in the nucleation of QDs reduced.CdSe QDs with the size-dispersion from 2.7 to 3.6 nm were synthesized via oleic acid-paraffin liquid system by controlling the reaction temperature from 180 to 220℃.Synthesized QDs were characterized by UV-vis absorption spectra and X-ray diffraction(XRD).The result of UV-vis absorption spectra showed that with increasing of reaction temperature,the first absorption peak was red-shifted and the size of QD increased.The result of XRD showed that the synthesized QDs were zinc-blende structure. | Licai Hao Zhongchen Bai Shuijie Qin Zhengping Zhang | 2017 | Journal of Semiconductors2017，38，4： | 1 |
| 7 | LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells显示文摘We recently demonstrated that leukocyte Ig-like receptor 4(LILRB4)expressed by monocytic acute myeloid leukemia(AML)cells mediates T-cell inhibition and leukemia cell infiltration via its intracellular domain.The cytoplasmic domain of LILRB4 contains three immunoreceptor tyrosine-based inhibitory motifs(ITIMs);the tyrosines at positions 360,412,and 442 are phosphorylation sites.Here,we analyzed how the ITIMs of LILRB4 in AML cells mediate its function.Our in vitro and in vivo data show that Y412 and Y442,but not Y360,of LILRB4 are required for T-cell inhibition,and all three ITIMs are needed for leukemia cell infiltration.We constructed chimeric proteins containing the extracellular domain of LILRB4 and the intracellular domain of LILRB1 and vice versa.The intracellular domain of LILRB4,but not that of LILRB1,mediates T-cell suppression and AML cell migration.Our studies thus defined the unique signaling roles of LILRB4 ITIMs in AML cells. | Zunling Li Mi Deng Fangfang Huang Changzhu Jin Shuang Sun Heyu Chen Xiaoye Liu Licai He Ali HSadek Cheng Cheng Zhang | 2020 | Cellular & Molecular Immunology2020，17，3： | 1 |
| 8 | Preparation and identification of monoclonal antibody against fumonisin B 1 and development of detection by Ic-ELISA显示文摘 | Sumei Ling Jie Pang Jinjin Yu Rongzhi Wang Licai Liu Yanling Ma Yuming Zhang Ni Jin Shihua Wang | 2013 | Toxicon2013，，： | 1 |
| 9 | Glial Cell-Derived Neurotrophic Factor Attenuates Neuropathic Pain in a Mouse Model of Chronic Constriction Injury: Possible Involvement of E-cadherin/p120ctn Signaling显示文摘 | Cunjin Wang Hongjun Wang Jun Pang Li Li Suming Zhang Ge Song Na Li Junping Cao Licai Zhang | 2014 | Journal of Molecular Neuroscience2014，，2： | 1 |
| 10 | High temperature tribological behavior of a Ti-46Al-2Cr-2Nb intermetallics显示文摘 | Jun Cheng Jun Yang Xinghua Zhang Hong Zhong Jiqiang Ma Fei Li Licai Fu Qinling Bi Jinshan Li Weimin Liu | 2012 | Intermetallics2012，，： | 1 |
| 11 | The Tribological Behavior of a Ti-46Al-2Cr-2Nb Alloy Under Liquid Paraffine Lubrication显示文摘 | Jun Cheng Jun Yang Jiqiang Ma Qinling Bi Xinghua Zhang Licai Fu Fei Li Shengyu Zhu Weimin Liu | 2012 | Tribology Letters2012，，3： | 1 |
| 12 | Mineralogical and geochemical anomalies of late Permian coals from the Fusui Coalfield, Guangxi Province, southern China: Influences of terrigenous materials and hydrothermal fluids显示文摘 | Shifeng Dai Weiguo Zhang Colin R. Ward Vladimir V. Seredin James C. Hower Xiao Li Weijiao Song Xibo Wang Huan Kang Licai Zheng Peipei Wang Dao Zhou | 2013 | International Journal of Coal Geology2013，，： | 1 |
| 13 | Impact of reclaimed water in the watercourse of Huai River on groundwater from Chaobai River basin, Northern China显示文摘 | Yilei YU Xianfang SONG Yinghua ZHANG Fandong ZHENG Licai LIU | 2017 | Frontiers of Structural and Civil Engineering2017，11，4： | 1 |
| 14 | High-Resolution Sequence Stratigraphy of Shallow Lacustrine Delta Front: The Second Member of Sangonghe Formation, Central Junggar Basin显示文摘Shallow lacustrine delta front(SLDF)comprises mainly sheetlike subaqueous distributary channels(SDC)formed in shallow,gentle,and tectonically steady slope(Cai and Zhu,2011).SDC proves an important hydrocarbon reservoir type in the Daqing oilfield,Changqing oilfield,and the newly discovered Moxizhuang oilfield in Central Junggar Basin.However,SDC tends to prograde | SONG Licai LIU Chenglin ZHANG Jiaodong QU Hongjie | 2015 | Acta Geologica Sinica(English Edition)2015，89，1： | 1 |
| 15 | Water quality of reclaimed water from treated urban wastewater in Chaobai River Basin,North China显示文摘The utilization of reclaimed water could be an efficient tool to alleviate water scarcity,especially for dry river augmentation.However,it is crucial to monitor water quality to ensure safety to human health and to avoid negative effects on the environment.Reclaimed water samples were collected bimonthly from May to November in 2010 in Chaobai River,and the physiochemical parameters were determined.The main results are as follows:The parameters exceeding the threshold value of the water guidelines are mainly nutrition related to nitrogen and phosphorus,which are known to increase the risk of eutrophication in surface waters.Additionally,nitrite and nitrate can be detrimental to human health.The majority of the parameters have a peaking concentration in May,whereas others either show significant temporal variation over the entire period or remain relatively constant in all four months.Correlation analysis shows that some parameters(pH,T and B) have no significant correlation with others,whereas significant positive correlation was found for Sr with EC and TDS,for CI with TDS,for Si02 with TP and for NO3-N with TN and a significant negative correlation between SO4 and Ba.According to principal component analysis,60.108%of the total data is represented by dominant solutes,and the second principal component with a percentage of 31.876 comprises parameters related to nitrogen.Subsequent cluster analysis of parameters identified four groups,which represent different compositions,and samples in May differ from others. | Yilei Yu Xianfang Song Yinghua Zhang Fandong Zheng Licai Liu | 2014 | Chinese Journal of Population,Resources and Environment2014，12，2： | 1 |
| 16 | Genetic Architecture and Functional Implications of the CSF‑Contacting Nucleus显示文摘We previously identified a unique nucleus,the cerebrospinal fluid(CSF)-contacting nucleus.This study aims to understand its gene architecture and preliminarily suggest its functions.The results showed that there were about 19,666 genes in this nucleus,of which 913 were distinct from the dorsal raphe nucleus(non-CSF contacting).The top 40 highly-expressed genes are mainly related to energy metabolism,protein synthesis,transport,secretion,and hydrolysis.The main neurotransmitter is 5-HT.The receptors of 5-HT and GABA are abundant.The channels for Cl–,Na+,K+,and Ca2+are routinely expressed.The signaling molecules associated with the CaMK,JAK,and MAPK pathways were identified accurately.In particular,the channels of transient receptor potential associated with nociceptors and the solute carrier superfamily members associated with cell membrane transport were significantly expressed.The relationship between the main genes of the nucleus and life activities is preliminarily verified. | Siyuan Song Yumin Yuan Lingling Xu Jun Jiang Ying Li Yao Yan Qing Li Fang Zhou Junli Cao Licai Zhang | 2023 | Neuroscience Bulletin2023，39，11： | 1 |
| 17 | Tracking Campylobacter contamination along a broiler chicken production chain from the farm level to retail in China显示文摘 | Licai Ma Yang Wang Jianzhong Shen Qijing Zhang Congming Wu | 2014 | International Journal of Food Microbiology2014，，： | 1 |
| 18 | Vagus nerve stimulation protects against cerebral injury after cardiopulmonary resuscitation by inhibiting inflammation through the TLR4/NF-κB and α7nAChR/JAK2 signaling pathways显示文摘BACKGROUND: Our previous research proved that vagus nerve stimulation(VNS) improved the neurological outcome after cardiopulmonary resuscitation(CPR) by activating α7 nicotinic acetylcholine receptor(α7nAChR) in a rat model, but the underlying mechanism of VNS in neuroprotection after CPR remains unclear.METHODS: In vivo, we established a mouse model of cardiac arrest(CA)/CPR to observe the survival rate, and the changes in inflammatory factors and brain tissue after VNS treatment. In vitro, we examined the effects of α7nAChR agonist on ischemia/reperfusion(I/R)-induced inflammation in BV2 cells under oxygen-glucose deprivation/reoxygenation(OGD/R) conditions. We observed the changes in cell survival rate, the levels of inflammatory factors, and the expressions of α7nAChR/Janus kinase 2(JAK2) and toll-like receptor 4(TLR4)/nuclear factor-κB(NF-κB).RESULTS: In vivo, VNS preconditioning enhanced functional recovery, improved the survival rate, and reduced hippocampal CA1 cell damage, and the levels of inflammatory mediators after CA/CPR. The application of α7nAChR agonists provided similar effects against cerebral injury after the return of spontaneous circulation(ROSC), while α7nAChR antagonists reversed these neuroprotective impacts. The in vitro results mostly matched the findings in vivo. OGD/R increased the expression of tumor necrosis factor-alpha(TNF-α), TLR4 and NF-κB p65. When nicotine was added to the OGD/R model, the expression of TLR4, NF-κB p65, and TNF-α decreased, while the phosphorylation of JAK2 increased, which was prevented by preconditioning with α7nAChR or JAK2 antagonists.CONCLUSION: The neuroprotective effect of VNS correlated with the activation of α7nAChR. VNS may alleviate cerebral IR injury by inhibiting TLR4/NF-κB and activating the α7nAChR/JAK2 signaling pathway. | Shuang Xu Lang Guo Weijing Shao Licai Liang Tingting Shu Yuhan Zhang He Huang Guangqi Guo Qing Zhang Peng Sun | 2023 | World Journal of Emergency Medicine2023，14，6： | 0 |
| 19 | Overview of the LAMOST survey in the first decade显示文摘The Large Sky Area Multi-Object Fiber Spectroscopic Telescope(LAMOST),also known as the Guoshoujing Telescope,is a major national scientific facility for astronomical research located in Xinglong,China.Beginning with a pilot survey in 2011,LAMOST has been surveying the night sky for more than 10 years.The LAMOST survey covers various objects in the Universe,from normal stars to peculiar ones. | Hongliang Yan Haining Li Song Wang Weikai Zong Haibo Yuan Maosheng Xiang Yang Huang Jiwei Xie Subo Dong Hailong Yuan Shaolan Bi Yaoquan Chu Xiangqun Cui Licai Deng Jianning Fu Zhanwen Han Jinliang Hou Guoping Li Chao Liu Jifeng Liu Xiaowei Liu Ali Luo Jianrong Shi Xuebing Wu Haotong Zhang Gang Zhao Yongheng Zhao | 2022 | The Innovation2022，3，2： | 0 |
| 20 | Analysis and Forecast of Urban Economic Vitality in Northeast China显示文摘Taking into account the passage of time,the original economic vitality index will vary with changes in social development,we use the BP neural network nearly a decade as the original GDP data for the next 30 years the GDP forecast.BP neural network in 1985,proposed by Rumelhart,the algorithm solves the system of learning problems multilayer neural network connection weights hidden layer[1].It consists of an input layer,a hidden layer,and an output layer.The principle is to continuously adjust the network weights and thresholds by transmitting errors backward and then correcting the errors to achieve the desired input-output mapping. | Xuan Cui Yali Zhang Licai Wei | 2020 | Journal of Finance Research2020，4，1： | 0 |
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