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| 1 | Ice radar investigation at Dome A, East Antarctica:Ice thickness and subglacial topography显示文摘Dome A, located in the central East Antarctic ice sheet (EAIS), is the highest summit of the Antarctic ice sheet. From ice-sheet evolution modeling results, Dome A is likely to preserve over one million years of the Earth's paleo-climatic and -environmental records, and considered an ideal deep ice core drilling site. Ice thickness and subglacial topography are critical factors for ice-sheet models to determine the timescale and location of a deep ice core. During the 21st and 24th Chinese National Antarctic Research Expedition (CHINARE 21, 2004/05; CHINARE 24, 2007/08), ground-based ice radar systems were used to a three-dimensional investigation in the central 30 km×30 km region at Dome A. The successfully obtained high resolution and accuracy data of ice thickness and subglacial topography were then interpolated into the ice thickness distribution and subglacial topography digital elevation model (DEM) with a regular grid resolution of 140.5 m×140.5 m. The results of the ice radar investigation indicate that the average ice thickness in the Dome A central 30 km×30 km region is 2233 m, with a minimal ice thickness of 1618 m and a maximal ice thickness of 3139 m at Kunlun Station. The subglacial topography is relatively sharp, with an elevation range of 949-2445 m. The typical, clear mountain glaciation morphology is likely to reflect the early evolution of the Antarctic ice sheet. Based on the ice thickness distribution and subglacial topography characteristics, the location of Kunlun Station was suggested to carry out the first high-resolution, long time-scale deep ice core drilling. However, the internal structure and basal environments at Kunlun Station still need further research to determine. | CUI XiangBin SUN Bo TIAN Gang TANG XueYuan ZHANG XiangPei JIANG YunYun GUO JingXue LI Xin | 2010 | Chinese Science Bulletin2010，55，4： | 11 |
| 2 | Preliminary results of ice radar investigation along the traverse between Zhongshan and Dome A in East Antarctic ice sheet:Ice thickness and subglacial topography显示文摘During the 24th Chinese National Antarctic Research Expedition(CHINARE 24,2007/08),a ground-based ice radar was used to survey ice thickness and subglacial topography along the 1170 km traverse between Zhongshan and Dome A in East Antarctic ice sheet(EAIS).Ice-bedrock interface was detected along 82%of the traverse and data was collected at a horizontal resolution of <5.6 m.The data was processed to produce curves of ice thickness distribution and subglacial topography along the traverse.The results indicate that,along the traverse,the average ice thickness is 2037 m,smaller than the average ice thickness in EAIS;the thickest ice is at 730 km,and the thinnest ice(891 m)is at the edge of the ice sheet,but the slightly larger ice thickness(1078 m) in inland appears at 1020 km;the average subglacial topography elevation is 728 m,greatly larger than the average value in EAIS, and the largest elevation reaches up to 2650 m at 1034 km.The lowest terrain is located at 765 km.In further inland of 900?1170 km,the subglacial topography is relatively high due to the existence of the Gamburtsev Subglacial Mountains in the region.Generally,the influence of subglacial topography on ice surface is not significant,except at 900 km where great rise of subglacial topography causes evident uplift of ice surface.Where ice-bedrock interface was detected,the frequent and strong change of ice thickness and subglacial topography in small-scale means large bedrock roughness along the traverse,and is considered as the result of the integrated influence of ice flow,basal environments and geology.The segment where bedrock was not detected has very large ice thickness.The strong ice flow there also makes internal structure more complicated and induces serious attenuation of radar signals. | CUI XiangBin SUN Bo TIAN Gang TANG XueYuan ZHANG XiangPei JIANG YunYun GUO JingXue LI Xin | 2010 | Chinese Science Bulletin2010，55，24： | 8 |
| 3 | Epidemiological characteristics of pulmonary tuberculosis in patients with pneumoconiosis based on its social determinants and risk factors in China:a cross-sectional study from 27 provinces显示文摘Background:Patients with pneumoconiosis have an elevated risk of contracting pulmonary tuberculosis(PTB)and need particular attention.However,extensive population-based studies on the prevalence of PTB in patients with pneumoconiosis have not been reported in China since 1992.This study aimed to investigate the epidemiological characteristics of PTB in patients with pneumoconiosis based on its social determinants and risk factors in China.Methods:Based on the Commission on Social Determinants of Health(CSDH)framework,data were obtained from a questionnaire survey of patients with pneumoconiosis from China’s 27 provinces(autonomous regions,municipalities)from December 2017 to June 2021.By chi-square and multivariate logistic regression analyses,the epidemiological characteristics of PTB in the patients were identified based on its prevalence and odds ratio(OR)and associated social determinants and risk factors.The population attributable fractions(PAFs)of significant risk factors were also calculated.Results:The prevalence of PTB in patients with pneumoconiosis(n=10,137)was 7.5%(95%confidence interval[CI]:7.0-8.0%).Multivariate logistic regression analysis showed that risk factors included in-hospital exposure to patients with PTB(OR=3.30,95%CI:2.77-3.93),clinically diagnosed cases(OR=3.25,95%CI:2.42-4.34),and northeastern regions(OR=2.41,95%CI:1.76-3.31).In addition,lack of work-related injury insurance(WRII),being born in a rural area,being unemployed,living in western regions,household exposure to patients with PTB,smoking,being underweight,complications of pulmonary bullae or pneumothorax,hospitalization history,and former drinkers among the rural patients were also statistically significant risk factors.Being born in a rural area,lack of WRII and in-hospital exposure to patients with PTB had higher PAFs,which were 13.2%(95%CI:7.9-18.5%),12.5%(95%CI:8.3-16.7%),and 11.6%(95%CI:8.8-14.3%),respectively.Conclusion:The prevalence of PTB in pneumoconiosis remains high in China;it is basically in line with the CSDH models and has its characteristics. | Huanqiang Wang Huaping Dai Jiayu He Xiangpei Lyu Xinran Zhang Tao Li | 2022 | Chinese Medical Journal2022，135，24： | 7 |
| 4 | Structure of the internal isochronous layers at Dome A,East Antarctica显示文摘Dome A (Kunlun Station) is considered a likely place for finding an ice core record reaching back to one million years. The internal isochronous layering of the Antarctic Ice Sheet, revealed by ice radar, is a prerequisite for selecting sites for deep ice core drilling that can be used for studying the paleoclimatic record. In 2004/2005, during the 21st Chinese National Antarctic Research Expedition (CHINARE 21), a 200-km long, continuous radar profile was obtained across Dome A. The internal layers along the profile were derived from the stratigraphy detected by the radar. The morphology of the isochronous layers shows that: (1) The internal layers in the shallow ice sheet (0-500 m) are generally flat, with no more than 50 m of layer intervals, and have typical synclines and anticlines in some localized regions. (2) At 500-2000 m below the surface of the ice sheet, the layers appear as 'bright layers', and the width of the layer intervals expands to 50-100 m. (3) When the basal topographic wavelengths are approximate to the thickness of the ice (3 km), the traced internal layers, with localized bumps or concave folds, are asymptotic parallel to the subglacial topography. For the longer topographic wavelengths (~20 km) wider than the thickness of the ice, the layers do not rise and fall with the basal topography. The internal layers surrounding some mountain peaks representing the most extreme variation in the terrain are sharply disturbed by the subglacial topography. (4) Layer discontinuity and fracture were detected in the basal ice sheet. Finally, by combining this new information with that derived from existing data regarding ice thickness, we were able to select three potential sites for reconstructing the age-depth relationship of the ice core. | TANG XueYuan SUN Bo ZHANG ZhanHai ZHANG XiangPei CUI XiangBin LI Xin | 2011 | Science China Earth Sciences2011，54，3： | 6 |
| 5 | Antarctic ice sheet GLIMMER model test and its simplified model on 2-dimensional ice flow显示文摘The 3-dimensional finite difference thermodynamic coupled model on Antarctic ice sheet,GLIMMER model,is described. An ide-alized ice sheet numerical test was conducted under the EISMINT-1 benchmark,and the characteristic curves of ice sheets under steady state were obtained. Based on this,this model was simplified from a 3-dimensional one to 2-dimensional one. Improvement of the dif-ference method and coordinate system was proposed. Evolution of the 2-dimensional ice flow was simulated under coupled temperature field conditions. The results showed that the characteristic curves deriving from the conservation of the mass,momentum and energy agree with the results of ice sheet profile simulated with GLIMMER model and with the theoretical results. The application prospect of the simplified 2-dimensional ice flow model to simulate the relation of age-depth-accumulation in Dome A region was discussed. | Xueyuan Tang Zhanhai Zhang Bo Sun Yuansheng Li Na Li Bangbing Wang Xiangpei Zhang | 2008 | Progress in Natural Science:Materials International2008，18，2： | 3 |
| 6 | A super pan-genomic landscape of rice显示文摘Pan-genomes from large natural populations can capture genetic diversity and reveal genomic complexity.Using de novo longread assembly,we generated a graph-based super pan-genome of rice consisting of a 251-accession panel comprising both cultivated and wild species of Asian and African rice.Our pan-genome reveals extensive structural variations(SVs)and gene presence/absence variations.Additionally,our pan-genome enables the accurate identification of nucleotide-binding leucine-rich repeat genes and characterization of their inter-and intraspecific diversity.Moreover,we uncovered grain weight-associated SVs which specify traits by affecting the expression of their nearby genes.We characterized genetic variants associated with submergence tolerance,seed shattering and plant architecture and found independent selection for a common set of genes that drove adaptation and domestication in Asian and African rice.This super pan-genome facilitates pinpointing of lineage-specific haplotypes for trait-associated genes and provides insights into the evolutionary events that have shaped the genomic architecture of various rice species. | Lianguang Shang Xiaoxia Li Huiying He Qiaoling Yuan Yanni Song Zhaoran Wei Hai Lin Min Hu Fengli Zhao Chao Zhang Yuhua Li Hongsheng Gao Tianyi Wang Xiangpei Liu Hong Zhang Ya Zhang Shuaimin Cao Xiaoman Yu Bintao Zhang Yong Zhang Yiqing Tan Mao Qin Cheng Ai Yingxue Yang Bin Zhang Zhiqiang Hu Hongru Wang Yang Lv Yuexing Wang Jie Ma Quan Wang Hongwei Lu Zhe Wu Shanlin Liu Zongyi Sun Hongliang Zhang Longbiao Guo Zichao Li Yongfeng Zhou Jiayang Li Zuofeng Zhu Guosheng Xiong Jue Ruan Qian Qian | 2022 | Cell Research2022，32，10： | 3 |
| 7 | Initiation and maintenance of plant stem cells in root and shoot apical meristems显示文摘Plant stem cells are a small group of cells with a self-renewal capacity and serve as a steady supply of precursor cells to form new differentiated tissues and organs in plants.Root stem cells and shoot stem cells,which are located in the root apical meristem and in the shoot apical meristem,respectively,play a critical role in plant longitudinal growth.These stem cells in shoot and root apical meristems remain as pluripotent state throughout the lifespan of the plant and control the growth and development of plants.The molecular mechanisms of initiation and maintenance of plant stem cells have been extensively investigated.In this review,we mainly discuss how the plant phytohormones,such as auxin and cytokinin,coordinate with the key transcription factors to regulate plant stem cell initiation and maintenance in root and shoot apical meristems.In addition,we highlight the common regulatory mechanisms of both root and shoot apical meristems. | Junxia Wang Yinghua Su Xiangpei Kong Zhaojun Ding Xian Sheng Zhang | 2020 | aBIOTECH2020，1，3： | 1 |
| 8 | Programmed cell death 1 genotypes are associated with susceptibility to systemic lupus erythematosus among Chinese显示文摘 | Qian Wang Dongqing Ye Jing Yin Xiangpei Li Guoqing Zhang Yongqing Zhang Xuejun Zhang | 2008 | Archives of Dermatological Research2008，，： | 1 |
| 9 | NAC1 regulates root ground tissue maturation by coordinating with the SCR/SHR-CYCD6;1 module in Arabidopsis显示文摘Precise spatiotemporal control of the timing and extent of asymmetric cell divisions(AcDs)is essential for plant development.In the Arabidopsis root,ground tissue maturation involves an additional AcD of the endo-dermis that maintains the inner cell layer as the endodermis and generates the middle cortex to the outside.Through regulation of the cell cycle regulator CYCLIND6;1(CYCD6;1),the transcription factors SCARECROW(SCR)and SHORT-ROOT(SHR)play critical roles in this process.In the present study,we found that loss of function of NAC1,a NAC transcription factor family gene,causes markedly increased periclinal cell divisions in the root endodermis.Importantly,NAC1 directly represses the transcription of CYCD6;1 by recruiting the co-repressor TOPLESS(TPL),creating a fine-tuned mechanism to maintain proper root ground tissue patterning by limiting production of middle cortex cells.Biochemical and genetic analyses further showed that NAC1 physically interacts with SCR and SHR to restrict excessive periclinal cell divisions in the endo-dermis during root middle cortex formation.Although NAC1-TPL is recruited to the CYCD6;1 promoter and represses its transcription in an SCR-dependent manner,NAC1 and SHR antagonize each other to regu-late the expression of CYCD6;1.Collectively,our study provides mechanistic insights into how the NAC1-TPL module integrates with the master transcriptional regulators SCR and SHR to control root ground tissue patterning by fine-tuning spatiotemporal expression of CYCD6;1 in Arabidopsis. | Chuantian Xie Cuiling Li Fengxia Wang Feng Zhang Jiajia Liu Junxia Wang Xiansheng Zhang Xiangpei Kong Zhaojun Ding | 2023 | Molecular Plant2023，16，4： | 1 |
| 10 | A complete assembly of the rice Nipponbare reference genome显示文摘Dear Editor,In 2005,the current commonly used rice reference genome(Oryza sativa ssp.japonica cv.Nipponbare)was initially released by the International Rice Genome Sequencing Project(International Rice Genome Sequencing Project,2005).Thereafter,the reference genome was further updated in 2013 with improved genome assembly(IRGSP-1.0)and gene annotations(MSU7,RAP-DB)(Kawahara et al.,2013;Sakai et al.,2013).In the past 10 years,this reference has been serving as one of the most important genetic resources for subsequent rice functional genomics efforts.As several rice genomes had been assembled into gapless chromosomes with only 2–5 telomeres absent(Li et al.,2021;Song et al.,2021;Zhang et al.,2022),the IRGSP1.0 and its annotations still performed as the most widely used reference.However,limitations of sequencing technology and intricate genomic organization led to an under-representation of complex regions in this reference,leaving a total of 72 major gaps(including 19 telomeres),167 minor gaps,and 779 unknown bases(Kawahara et al.,2013),with an estimated length of3%of the genome unsolved. | Lianguang Shang Wenchuang He Tianyi Wang Yingxue Yang Qiang Xu Xianjia Zhao Longbo Yang Hong Zhang Xiaoxia Li Yang Lv Wu Chen Shuo Cao Xianmeng Wang Bin Zhang Xiangpei Liu Xiaoman Yu Huiying He Hua Wei Yue Leng Chuanlin Shi Mingliang Guo Zhipeng Zhang Bintao Zhang Qiaoling Yuan Hongge Qian Xinglan Cao Yan Cui Qianqian Zhang Xiaofan Dai Congcong Liu Longbiao Guo Yongfeng Zhou Xiaoming Zheng Jue Ruan Zhukuan Cheng Weihua Pan Qian Qian | 2023 | Molecular Plant2023，16，8： | 1 |
| 11 | D53: The Missing Link in Strigolactone Signaling显示文摘Strigolactones (SLs),a group of small carotenoid-derived terpenoid lactones,have been recently identified as plant hormones controlling plant architecture through modulating shoot and root branching (Brewer et al.,2013).SLs were first discovered in the rhizosphere because of their involvement in both symbiotic and parasitic interactions.Deficiencies in SL biosynthesis and perception lead to excessive growth of axillary bud,which is exemplified through various mutants such as max1,max2,max3,and max4 (more axillary growth) in Arabidopsis,d27,d10,d14,d3 (dwarf) in rice,dad3,dad1,dad2 (decreased apical dominance) in petunia,and rms5,rms1,rms4 (ramosus) in pea (de Saint Germain et al.,2013).Among these,D14/AtD14/DAD2 and D3/MAX2/PhMAX2A,which encode a predicted α/β-fold hydrolase and an F-box protein,respectively,have been proved to play important roles in SLs perception (Hamiaux et al.,2012;Zhao et al.,2013).A previous study shows that the D3 F-box protein is a key component of the Skp-Cullin-F-box (SCF) E3 ubiquitin ligase complex,implying that ubiquitination and proteasome-mediated degradation of targets,which were so far unknown,might be essential for SL signaling. | Xiangpei Kong Maolin Zhang Zhaojun Ding | 2014 | Molecular Plant2014，7，5： | 1 |
| 12 | An analysis of the multi-fold method for GPR exploration显示文摘多种的技术广泛地作为提高有用信号并且压制噪音干扰极大地增加信号到噪音比率(S/N ) 的一个方法在地震探索被使用。作者把它介绍给渗透地面的雷达(GPR ) 调查并且把试验性的结果比作常规介绍方法为 GPR 表明这种技术的可行性和优点探索。基于试验性的数据,作者总结 GPR 波浪繁殖规则和多种的获得的参数并且处理。是一次有用尝试充实 GPR 调查技术被证明。 | Wang Bangbing Tian Gang Sun Bo Guo Jinxue Zhang Xiangpei | 2006 | Applied Geophysics2006，3，3： | 1 |
| 13 | A centromere map based on super pan-genome highlights the structure and function of rice centromeres显示文摘Rice(Oryza sativa)is a significant crop worldwide with a genome shaped by various evolutionary factors.Rice centromeres are crucial for chromosome segregation,and contain some unreported genes.Due to the diverse and complex centromere region,a comprehensive understanding of rice centromere structure and function at the population level is needed.We constructed a high-quality centromere map based on the rice super pangenome consisting of a 251-accession panel comprising both cultivated and wild species of Asian and African rice.We showed that rice centromeres have diverse satellite repeat CentO,which vary across chromosomes and subpopulations,reflecting their distinct evolutionary patterns.We also revealed that long terminal repeats(LTRs),especially young Gypsy-type LTRs,are abundant in the peripheral CentO-enriched regions and drive rice centromere expansion and evolution.Furthermore,high-quality genome assembly and complete telomere-to-telomere(T2T)reference genome enable us to obtain more centromeric genome information despite mapping and cloning of centromere genes being challenging.We investigated the association between structural variations and gene expression in the rice centromere.A centromere gene,OsMAB,which positively regulates rice tiller number,was further confirmed by expression quantitative trait loci,haplotype analysis and clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated protein9 methods.By revealing the new insights into the evolutionary patterns and biological roles of rice centromeres,our finding will facilitate future research on centromere biology and crop improvement. | Yang Lv Congcong Liu Xiaoxia Li Yueying Wang Huiying He Wenchuang He Wu Chen Longbo Yang Xiaofan Dai Xinglan Cao Xiaoman Yu Jiajia Liu Bin Zhang Hua Wei Hong Zhang Hongge Qian Chuanlin Shi Yue Leng Xiangpei Liu Mingliang Guo Xianmeng Wang Zhipeng Zhang Tianyi Wang Bintao Zhang Qiang Xu Yan Cui Qianqian Zhang Qiaoling Yuan Noushin Jahan Jie Ma Xiaoming Zheng Yongfeng Zhou Qian Qian Longbiao Guo Lianguang Shang | 2024 | Journal of Integrative Plant Biology2024，66，2： | 0 |
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