3篇
您的检索式：作者名="Zhaodi Fan"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Designing N-doped graphene/ReSe_(2)/Ti_(3)C_(2) MXene heterostructure frameworks as promising anodes for high-rate potassium-ion batteries显示文摘Developing high-performance anodes for potassium ion batteries(KIBs) is of paramount significance but remains challenging.In the normal sense,electrode materials are prepared by ubiquitous wet chemical routes,which otherwise might not be versatile enough to create desired heterostructures and/or form clean interfacial areas for fast transport of K-ions and electrons.Along this line,rate capability/cycling stability of resulting KIBs are greatly handicapped.Herein we present an all-chemical vapor deposition approach to harness the direct synthesis of nitrogen-doped graphene(NG)/rhenium diselenide(ReSe_2)hybrids over three-dimensional MXene supports as superior heterostructure anode material for KIBs.In such an innovative design,1 T'-ReSe2 nanoparticles are sandwiched in between the NG coatings and MXene frameworks via strong interfacial interactions,thereby affording facile K~+ diffusion,enhancing overall conductivity,boosting high-power performance and reinforcing structural stability of electrodes.Thus-constructed anode delivers an excellent rate performance of 138 mAh g^(-1) at 10.0 A g^(-1) and a high reversible capacity of 90 mAh g^(-1) at 5 A g^(-1) after 300 cycles.Furthermore,the potassium storage mechanism has been systematically probed by advanced in situlex situ characterization techniques in combination with first principles computations. | Zhou Xia Xiwen Chen Haina Cia Zhaodi Fan Yuyang Yi Wanjian Yin Nan Wei Jingsheng Cai Yanfeng Zhang Jingyu Sun | 2021 | Journal of Energy Chemistry2021，30，2： | 9 |
| 2 | Two-dimensional cobalt metal-organic frameworks for efficient C_3H_6/CH_4 and C_3H_8/CH_4 hydrocarbon separation显示文摘A Co-based two-dimensional(2 D) microporous metal-organic frameworks, [Co_2(TMTA)(DMF)2(H_2O)_2]·NO_3^-·DMF(UPC-32) has been synthesized based on 4,4',4''-(2,4,6-trimethylbenzene-1,3,5-triyl)tribenzoic acid(H_3TMTA). UPC-32 features a 2 D microporous framework exhibits high adsorption of H_2(118.2 cm^3/g, 1.05 wt%, at 77 K), and adsorption heat(Q_(st)) of CO_2(34–46 k J/mol). UPC-32 with narrow distance between layers(3.8 ?) exhibits high selectivity of C_3H_6/CH_4(31.46) and C_3H_8/CH_4(28.04) at298 K and 1 bar. It is the first 2 D Co-MOF that showed selective separation of C3 hydrocarbon from CH4. | Weidong Fan Yutong Wang Zhenyu Xiao Zhaodi Huang Fangna Dai Rongming Wang Daofeng Sun | 2018 | Chinese Chemical Letters2018，29，6： | 1 |
| 3 | Hepatic COX1 loss leads to impaired autophagic flux and exacerbates nonalcoholic steatohepatitis显示文摘The mechanisms underlying autophagic defects in nonalcoholic steatohepatitis(NASH)remain largely unknown.We aimed to elucidate the roles of hepatic cyclooxygenase 1(COX1)in autophagy and the pathogenesis of diet-induced steatohepatitis in mice.Human nonalcoholic fatty liver disease(NAFLD)liver samples were used to examine the protein expression of COX1 and the level of autophagy.Cox1^(Δhepa)mice and their wildtype littermates were generated and fed with 3 different NASH models.We found that hepatic COX1 expression was increased in patients with NASH and diet induced NASH mice models accompanied by impaired autophagy.COX1 was required for basal autophagy in hepatocytes and liver specific COX1 deletion exacerbated steatohepatitis by inhibiting autophagy.Mechanistically,COX1 directly interacted with WD repeat domain,phosphoinositide interacting 2(WIPI2),which was crucial for autophagosome maturation.Adeno-associated virus(AAV)-mediated rescue of WIPI2 reversed the impaired autophagic flux and improved NASH phenotypes in Cox1^(Δhepa)mice,indicating that COX1 deletion-mediated steatohepatitis was partially dependent on WIPI2-mediated autophagy.In conclusion,we demonstrated a novel role of COX1 in hepatic autophagy that protected against NASH by interacting with WIPI2.Targeting the COX1 WIPI2 axis may be a novel therapeutic strategy for NASH. | Qian Yu Chang Li Qinghui Niu Jigang Wang Zhaodi Che Ke Lei He Ren Boyi Ma Yixing Ren Pingping Luo Zhuming Fan Huan Zhang Zhaohui Liu George L.Tipoe Jia Xiao | 2023 | Acta Pharmaceutica Sinica B2023，13，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员