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| 1 | TCMSTD 1.0: a systematic analysis of the traditional Chinese medicine system toxicology database显示文摘Dear Editor,The safety and modernization of traditional Chinese medicine (TCM) are significant concerns for users’ lives and health. Recently, the adverse effects caused by TCM and traditional nontoxic TCM have been frequently reported (Joo et al., 2020;Liu et al., 2021). As the safety of TCM continues to attract widespread attention, many researchers have been investigating the toxicity of TCM in regard to the toxic ingredients, effects, mechanisms, and detoxification strategies in TCM (Figure S1 in Supporting Information). Although some TCMs cause toxic reactions, they also play key roles in treating certain unignorable diseases (Fang et al., 2022).Therefore, toxicity research is crucial and urgently needed to develop and safely use TCM. | Lili Song Wenxiu Qian Hongqing Yin Yu Sun Xiuyan Sun Guohui Li Junjie He Yanxue Zheng Yue Zhang Jiayi Wang Yubo Li | 2023 | Science China(Life Sciences)2023，66，9： | 3 |
| 2 | Optimization of sampling frequency for routine river water quality monitoring显示文摘Sampling frequency is an important factor to be considered during the design of a water monitoring network,and the cost-effective selection of possible ways and means for the optimization of sampling frequency is still needed.This paper introduces water pollution index deviation ratio comparison(WPI DRC),a procedure for the optimization of sampling frequency for a routine river water quality monitoring system.Sampling frequency optimized using WPI DRC at monitoring station X5 in the mainstream of Xiangjiang River is compared with that established using the traditional Statistical Algorithm method.The result of comparison indicates that WPI DRC is more feasible than the traditional one.And then,the sampling frequencies for other 16 monitoring stations also have been optimized,and the results show the sampling frequencies of all the stations except that X4 are reduced,and there is no unacceptable difference between water quality evaluation results at 17 stations before and after the optimization.Therefore,it is concluded that WPI DRC is an effective optimization process with operable results,which can be used to fulfill the requirement of practical monitoring work. | LIU Yan ZHENG BingHui WANG Mei XU YanXue QIN YanWen | 2014 | Science China Chemistry2014，57，5： | 2 |
| 3 | Global exponential stability of delayed periodic dynamical systems显示文摘 | Zheng Yanxu Chen Tianping | 2004 | Physics Letters A2004，322，56： | 1 |
| 4 | A facile strategy for the fabrication of highly stable superhydrophobic cotton fabric using amphiphilic fluorinated triblock azide copolymers 显示文摘 | Li Guang Zheng Haiting Wang Yanxue | 2010 | Polymer2010，51，9： | 1 |
| 5 | Drug-induced hierarchical self-assembly of poly(amino acid)for efficient intracellular drug delivery显示文摘As a potent anticancer drug,gambogic acid(GA)suffers from its poor water solubility and low chemical stability and shows a limited clinical outcome.To address this problem,we report here a simple and effective strategy to immobilize and deliver GA using a reducible diblock poly(amino acid)as a model.The electrostatic interaction between GA and polymer enables a high drug loading content up to 53.6%.Moreover,the drug complexation induces a micelle-to-vesicle transformation,combined with a conformation tra nsition from random coil to a-helix.The hierarchically assembled drug nanocomplexes can serve as a smart carrier for efficient cell internalization and triggered release of multiple drugs under intracellular acidic and reductive conditions,resulting in a synergistic antitumor efficacy in vitro.This work provides a new insight into the drug-carrier interaction and a facile nanoplatform for drug delivery applications. | Zifen Li Yanxue Yang Chuan Peng Hang Liu Rui Yang Yi Zheng Lulu Cai Hong Tan Qiang Fu Mingming Ding | 2021 | Chinese Chemical Letters2021，32，4： | 1 |
| 6 | South-hemispheric marine aerosol Hg and S isotope compositions reveal different oxidation pathways显示文摘Particle-bound mercury(PBM)records the oxidation of elemental mercury,of which the main oxidation pathways(Br∙/Cl∙/OH∙/O3)remain unclear,especially in the Southern Hemisphere.Here,we present latitudinal covariations of Hg and Sisotopic anomalies in cross-hemispheric marine aerosols that evidence an equator-to-poleward transition of Hg oxidants from OH∙/O3 in tropics to Br∙/Cl∙in polar regions highlighting thus the presence of distinct oxidation processes producing PBM.The correlations between Hg,S and O-isotopic compositions measured in PBM,sulfates and nitrates respectively within the aerosols highlight the implication of common oxidants in their formations at different latitudes.Our results open a new window to better quantify the present-day atmospheric Hg,S and N budgets and to evaluate the influences of aerosols on climate and ecosystems once the isotopic fractionations associated with each process have been determined. | David AuYang Jiubin Chen Wang Zheng Yanxu Zhang Guitao Shi Jeroen ESonke Pierre Cartigny Hongming Cai Wei Yuan Liangzhi Liu Pengxue Gai Congqiang Liu | 2022 | National Science Open2022，1，2： | 1 |
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