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| 1 | CTLA4 Silencing with siRNA Promotes Deviation of Th1/Th2 in Chronic Hepatitis B Patients显示文摘To determine whether RNA interference (RNAi) could block cytotoxic T-lymphocyte antigen 4 (CTLA4) in human lymphocytes in vitro and promote IFN-γ and IL-2 secretions, three small interfering RNAs (siRNAs) were selected based on target specificity sequences of human CTLA4 and transfected into human lymphocytes of chronic HBV patients. As a result, the expression of human CTLA4 mRNA was efficiently suppressed by all the three siRNAs. Compared with negative control (siRNA-co), siRNA-1 inhibited the expression of CTLA4 most efficiently and was used in the further study. The expressions of IFN-γ and IL-2 were upregulated and the level of IL-4 was almost unchanged in lymphocytes transfected with siRNA-1 compared with the blank control. These results indicated that siRNA-1 led to IFN-γ and IL-2 secretions, which is a main response of Th1/Th2. In a conclusion, RNAi significantly suppressed the expression of human CTLA4 mRNA in human lymphocytes in vitro, and could induce Th1/Th2 response. It could be a new therapeutic strategy for chronic HBV infection. | Yongsheng Yu Hao Wu Zhenghao Tang Guoqing Zang | 2009 | Cellular & Molecular Immunology2009，6，2： | 14 |
| 2 | Single crystalline CH_3NH_3PbI_3 self-grown on FTO/TiO_2 substrate for high efficiency perovskite solar cells显示文摘Since its first report in 2009,CH_3NH_3PbI_3-based perovskite solar cells(PSCs)have emerged as one of the most exciting developments in the next generation photovoltaic(PV)technologies[1],with its PV conversion efficiency(PCE)rising spectacularly from3.81% to 22.1% in just 7 years.Such rapid advance is | Jinjin Zhao Guoli Kong Shulin Chen Qian Li Boyuan Huang Zhenghao Liu Xingyuan San Yujia Wang Chen Wang Yunce Zhen Haidan Wen Peng Gao Jiangyu Li | 2017 | Science Bulletin2017，62，17： | 12 |
| 3 | Dendritic cell-based vaccination with lentiviral vectors encoding ubiquitinated hepatitis B core antigen enhances hepatitis B virus-specific immune responses in vivo显示文摘肝炎 B 病毒(HBV ) 的活动特定的细胞毒素的 T 淋巴细胞(CTL ) 戏在 HBV 的清理的一个占优势的角色。树枝状的房间(DC ) 是关键介绍抗原的房间并且在有免疫力的回答的开始起一个重要作用。我们以前验证了有效地编码 ubiquitinated 肝炎 B 核心抗原(LV-Ub-HBcAg ) 的那 lentiviral 向量导致成熟的 transduced DC,和成熟 DC 高效地导致了 T 房间极化到 Th1 并且产生了 HBcAg 特定的 CTL 前 vivo。在这研究,在 BALB/c 老鼠的 LV-Ub-HBcAg 的 HBV 特定的有免疫力的回答(H-2K d ) 被评估。LV-Ub-HBcAg 的直接注射增加了 cytokines IL-2 和 IFN- 的生产,这被显示出,得到了强壮的抗体回答,并且显著地产生了 IFN-+ 有在 BALB/c 老鼠的 HBV 特定的 CTL 回答的 CD8 + T 房间。另外, LV-Ub-HBcAg 的直接注射导致了有势力 anti-HBV 免疫者回答,类似于得到由的那些在 vitro-transduced DC。在结论,基于 DC 的治疗学的疫苗的 LV-Ub-HBcAg 得到了特定的抗体免疫者回答并且在 vivo 导致了柔韧的特定的 CTL 活动。 | Shenglan Dai Meng Zhuo Linlin Song Xiaohua Chen Yongsheng Yu Zhenghao Tang Guoqing Zang | 2015 | Acta Biochimica et Biophysica Sinica2015，47，11： | 9 |
| 4 | Design of Embryo-electronic Systems Capable of Self-diagnosing and Self-healing and Configuration Control显示文摘空航天器工作于恶劣空间环境,要求其测控系统硬件具有高可靠性和自修复能力。胚胎电子系统是一种具有自检测、自修复能力的仿生硬件.根据多细胞生物体结构中自检测自修复机制,设计了包含DNA存储器、功能模块、状态控制和自诊断模块以及物理连接模块等的胚胎电子系统体系结构及其容错机制。又针对目前配置存储器无法满足大规模胚胎电子系统要求,提出了基于移位寄存器的胚胎电子系统配置存储器新结构及其配置控制技术。设计了基于移位寄存器的胚胎电子系统配置存储器的整体结构,整个胚胎电子系统的配置存储器连接在一起形成一个链式结构。并设计了配置存储器单元的内部电路以及基于移位寄存器的胚胎电子系统配置控制和动态重构方法。实验表明,该系统既能够实现胚胎电子系统的故障自修复和胚胎电子系统功能的在线动态重构,该存储器结构相比基于SRAM的配置存储器结构,在128×128以上的大规模胚胎电子系统时,可以节约大约90%以上的存储器面积。 | Xu Guili Xia Zhenghao Wang Haibin Zhang Zhai Wang Youren | 2009 | Chinese Journal of Aeronautics2009，22，6： | 9 |
| 5 | Parameters identification of chaotic systems based on artificial bee colony algorithm combined with cuckoo search strategy显示文摘Artificial bee colony(ABC) algorithm is motivated by the intelligent behavior of honey bees when seeking a high quality food source. It has a relatively simple structure but good global optimization ability. In order to balance its global search and local search abilities further, some improvements for the standard ABC algorithm are made in this study. Firstly, the local search mechanism of cuckoo search optimization(CS) is introduced into the onlooker bee phase to enhance its dedicated search; secondly, the scout bee phase is also modified by the chaotic search mechanism. The improved ABC algorithm is used to identify the parameters of chaotic systems, the identified results from the present algorithm are compared with those from other algorithms. Numerical simulations, including Lorenz system and a hyper chaotic system, illustrate the present algorithm is a powerful tool for parameter estimation with high accuracy and low deviations. It is not sensitive to artificial measurement noise even using limited input data. | DING ZhengHao LU ZhongRong LIU JiKe | 2018 | Science China(Technological Sciences)2018，61，3： | 8 |
| 6 | Inhibition of fibroblast growth factor 2-induced apoptosis involves survivin expression, protein kinase Cα activation and subcellular translocation of Smac in human small cell lung cancer cells显示文摘为了调查(FGF-2 ) 成纤维细胞生长因素 2 在人的小房间肺癌症房间线 H446 由禁止 apoptosis 的机制,使遭到了到浆液饥饿, apoptosis 被流动 cytometry,染色的 Hoechst 33258, caspase-3 活动,和 DNA 破碎评估。FGF-2 和蛋白质 kinase C (PKC ) translocation 导致的 Survivin 表示被 subcellular 分别和西方的污点分析检测。另外,到细胞质的从线粒体的 Smac 的 FGF-2-in-duced 版本被西方的弄污和 immunofluorescence 分析。FGF-2 减少了浆液饥饿和起来调整的 survivin 表示在剂量依赖者 andtime-dependentmanner 在 H446 房间导致的 apoptosis, andinhibitedcaspase-3 活动。FGF-2 也从线粒体禁止了 Smac 的版本到浆液饥饿导致并且从细胞质增加了 PKC translocation 到房间膜的细胞质。另外, PKC 禁止者禁止了 survivin 的表示。FGF-2 起来调整在 H446 房间和块的 survivin 蛋白质的表示到细胞质的从线粒体的 Smac 的版本。PKC 调整了 FGF-2-induced survivin 表示。因此, survivin, Smac,和 PKC 可能在人的小房间肺癌症房间由 FGF-2 在 apoptosis 的抑制起重要作用。 | Desheng Xiao Kuansong Wang Jianhua Zhou Huiqiu Cao Zhenghao Deng Yongbin Hu Xiahui Qu Jifang Wen | 2008 | Acta Biochimica et Biophysica Sinica2008，40，4： | 7 |
| 7 | Delivery of Tapasin-modified CTL epitope peptide via cytoplasmic transduction peptide induces CTLs by JAK/STAT signaling pathway in vivo显示文摘特定的细胞毒素的 T 淋巴细胞(CTL ) 玩的肝炎 B 病毒(HBV ) 在病毒的控制和清理的一个重要角色。最近的研究阐明了那 Tapasin, endoplasmic 蜂窝胃女伴,是看起来在装载肽的过程必要的一个著名分子。Janus kinase/signal 变换器和小径玩的抄写(JAK/STAT ) 的使活跃之物在有免疫力的反应的一个重要角色规定和 cytokines 分泌物。我们以前证实了熔化蛋白质 CTP-HBcAg 18-27-Tapasin 能便于骨头髓的成熟导出的树枝状的房间并且在 vitro 提高特定的 CTL 回答,它可能与 JAK/STAT 发信号的激活被联系小径。为了进一步探索 JAK/STAT 发信号小径是否参予了特定的有免疫力的回答,由我们压制了的 CTP-HBcAg 18-27-Tapasin, 调停了有在 vivo 的药理学禁止者(AG490 ) 的 JAK/STAT 小径。我们的研究证明 IFN-+-CD8+ T 房间的数字在被 AG490 堵住以后与另外的组相比显著地被减少。IFN-+-CD4+ T 房间和 IL-2-CD4 + T 房间的百分比也被减少。而且, Jak2, Tyk2, STAT1,和 STAT4 的更低的表示层次在 AG490 被检测组。另外,象 Th1 一样 cytokines 的分泌物层次被减少,更弱的特定的 T 房间回答在 AG490 组被观察。而且,在这条小径在 HBV 转基因的老鼠被禁止以后,在浆液的 HBV DNA 和 HBsAg 的层次和在肝纸巾的 HBsAg 和 HBcAg 的表示层次被提高。这些结果证明表明小径的 JAK/STAT 参予 CTP-HBcAg 18-27-Tapasin 导致的 Th1 面向的有免疫力的反应,这可能为 HBV 免疫疗法提供一个理论基础。 | Shanshan Wu Xiaohua Chen Yuyan Tang Yi Zhang Dan Li Jie Chen Jieling Wang Zhenghao Tang Guoqing Zang Yongsheng Yu | 2018 | Acta Biochimica et Biophysica Sinica2018，50，2： | 6 |
| 8 | Cylindrical vector beam multiplexer/demultiplexer using off-axis polarization control显示文摘The emergence of cylindrical vector beam(CVB)multiplexing has opened new avenues for high-capacity optical communication.Although several configurations have been developed to couple/separate CVBs,the CVB multiplexer/demultiplexer remains elusive due to lack of effective off-axis polarization control technologies.Here we report a straightforward approach to realize off-axis polarization control for CVB multiplexing/demultiplexing based on a metal–dielectric–metal metasurface.We show that the left-and right-handed circularly polarized(LHCP/RHCP)components of CVBs are independently modulated via spin-to-orbit interactions by the properly designed metasurface,and then simultaneously multiplexed and demultiplexed due to the reversibility of light path and the conservation of vector mode.We also show that the proposed multiplexers/demultiplexers are broadband(from 1310 to 1625 nm)and compatible with wavelength-division-multiplexing.As a proof of concept,we successfully demonstrate a four-channel CVB multiplexing communication,combining wavelength-division-multiplexing and polarization-division-multiplexing with a transmission rate of 1.56 Tbit/s and a bit-error-rate of 10^(−6) at the receive power of−21.6 dBm.This study paves the way for CVB multiplexing/demultiplexing and may benefit high-capacity CVB communication. | Shuqing Chen Zhiqiang Xie Huapeng Ye Xinrou Wang Zhenghao Guo Yanliang He Ying Li Xiaocong Yuan Dianyuan Fan | 2021 | Light(Science & Applications)2021，10，12： | 6 |
| 9 | Myt1L Promotes Differentiation of Oligodendrocyte Precursor Cells and is Necessary for Remyelination After Lysolecithin-Induced Demyelination显示文摘The differentiation and maturation of oligodendrocyte precursor cells(OPCs) is essential for myelination and remyelination in the CNS. The failure of OPCs to achieve terminal differentiation in demyelinating lesions often results in unsuccessful remyelination in a variety of human demyelinating diseases. However, the molecular mechanisms controlling OPC differentiation under pathological conditions remain largely unknown. Myt1 L(myelin transcription factor 1-like), mainly expressed in neurons,has been associated with intellectual disability, schizophrenia, and depression. In the present study, we found that Myt1 L was expressed in oligodendrocyte lineage cells during myelination and remyelination. The expression level of Myt1 L in neuron/glia antigen 2-positive(NG^(2+))OPCs was significantly higher than that in mature CC1^+ oligodendrocytes. In primary cultured OPCs,overexpression of Myt1 L promoted, while knockdown inhibited OPC differentiation. Moreover, Myt1 L was potently involved in promoting remyelination after lysolecithin-induced demyelination in vivo. Ch IP assays showed that Myt1 L bound to the promoter of Olig1 and transcriptionally regulated Olig1 expression. Taken together, our findings demonstrate that Myt1 L is an essential regulator of OPC differentiation, thereby supporting Myt1 L as a potential therapeutic target for demyelinating diseases. | Yanqing Shi Qi Shao Zhenghao Li Ginez A. Gonzalez Fengfeng Lu Dan Wang Yingyan Pu Aijun Huang Chao Zhao Cheng He Li Cao | 2018 | Neuroscience Bulletin2018，34，2： | 6 |
| 10 | The modification of Tapasin enhances cytotoxic T lymphocyte activity of intracellularly delivered CTL epitopes via cytoplasmic transduction peptide显示文摘以前的研究证明了基于肝炎 B 病毒(HBV ) 的改进,特定的细胞毒素的 T 淋巴细胞(CTL ) 活动可以导致的治疗学的疫苗在感染 HBV 的个人的病毒的清理。endoplasmic 蜂窝胃(嗯) 女伴 Tapasin 在主要 histocompatibility 起一个重要作用建筑群(MHC ) 一级汇编并且由允许更多的肽是进 ER 的 translocated 提高特定的 MHC 班我限制 CTL 活动。联合核心抗原(HBcAg ) CTL epitope,细胞质的 transduction 肽(CTP ) 的渗透房间的性质,和女伴 Tapasin 可以得到的肝炎 B 的特性柔韧的特定的 HBV 有免疫力的回答。在现在的学习,我们在 vitro 证实了 CTP-HBcAg1827-Tapasin 熔化蛋白质的细胞质的本地化偏爱并且在支持骨头上评估了效果导出髓的树枝状的房间(BMDC ) 成熟和提高的 T 房间反应到产生特定的 CTL。我们的结果证明那 CTP-HBcAg1827-Tapasin 熔化蛋白质不能仅仅确切并且有效地渗透进细胞质提高 Tapasin 表示,而且增加表面分子(CD80, CD83, CD86,和 MHC-I ) 和 DC 的 cytokine (IL-12p70 ) 的分泌物的表示。而且,与上述熔化蛋白质对待的 DC 显著地与控制组相比在 vitro, IFN-+CD8+ T 房间的百分比和特定的 CTL 回答增加了增殖的 T 房间的 cytokine 分泌物。在结论, Tapasin 的修正能提高经由细胞内部的交货指向抗原到 DC 的演讲并且高效地得到特定的 CTL 有免疫力的回答。 | Xiaohua Chen Honghong Liu Zhenghao Tang Yongsheng Yu Guoqing Zang | 2013 | Acta Biochimica et Biophysica Sinica2013，45，3： | 6 |
| 11 | Shikimic Acid Promotes Oligodendrocyte Precursor Cell Differentiation and Accelerates Remyelination in Mice显示文摘The obstacle to successful remyelination in demyelinating diseases, such as multiple sclerosis, mainly lies in the inability of oligodendrocyte precursor cells(OPCs) to differentiate, since OPCs and oligodendrocytelineage cells that are unable to fully differentiate are found in the areas of demyelination. Thus, promoting the differentiation of OPCs is vital for the treatment of demyelinating diseases. Shikimic acid(SA) is mainly derived from star anise, and is reported to have antiinfluenza, anti-oxidation, and anti-tumor effects. In the present study, we found that SA significantly promoted the differentiation of cultured rat OPCs without affecting their proliferation and apoptosis. In mice, SA exerted therapeutic effects on experimental autoimmune encephalomyelitis(EAE), such as alleviating clinical EAE scores, inhibiting inflammation, and reducing demyelination in the CNS. SA also promoted the differentiation of OPCs as well as their remyelination after lysolecithin-induced demyelination.Furthermore, we showed that the promotion effect of SA on OPC differentiation was associated with the up-regulation of phosphorylated m TOR. Taken together, our resultsdemonstrated that SA could act as a potential drug candidate for the treatment of demyelinating diseases. | Fengfeng Lu Dou Yin Yingyan Pu Weili Liu Zhenghao Li Qi Shao Cheng He Li Cao | 2019 | Neuroscience Bulletin2019，35，3： | 4 |
| 12 | Nanosecond photoelectric effects in all-oxide p-n junction of La_(0.9)Sr_(0.1)MnO_(3)/SrNb_(0.01)Ti_(0.99)O_(3)显示文摘Nanosecond (ns) photoelectric effects have been observed in all-oxide p-n junctions of La0.9Sr0.1MnO3/SrNb0.01Ti0.99O3 for the first time. The rise time was about 23 ns and the full width at half maximum was about 125 ns for the open-circuit photovoltaic pulse when the La0.9Sr0.1MnO3 thin film in the p-n junction was irradiated by a laser of ~20 ns pulse duration and 308 nm wavelength. The photovoltaic sensitivity was 80 mV/mJ for a 308 nm laser pulse. | HUANG Yanhong L(U) Huibin HE Meng ZHAO Kun CHEN Zhenghao CHENG Bolin ZHOU Yueliang JIN Kuijuan DAI Shouyu YANG Guozhen | 2005 | Science China(Physics,Mechanics & Astronomy)2005，48，3： | 4 |
| 13 | Cyclin-dependent Kinase 18 Promotes Oligodendrocyte Precursor Cell Differentiation through Activating the Extracellular Signal-Regulated Kinase Signaling Pathway显示文摘The correct differentiation of oligodendrocyte precursor cells(OPCs) is essential for the myelination and remyelination processes in the central nervous system.Determining the regulatory mechanism is fundamental to the treatment of demyelinating diseases. By analyzing the RNA sequencing data of different neural cells, we found that cyclin-dependent kinase 18(CDK18) is exclusively expressed in oligodendrocytes. In vivo studies showed that the expression level of CDK18 gradually increased along with myelin formation during development and in the remyelination phase in a lysophosphatidylcholine-induced demyelination model, and was distinctively highly expressed in oligodendrocytes. In vitro overexpression and interference experiments revealed that CDK18 directly promotes the differentiation of OPCs, without affecting their proliferation or apoptosis. Mechanistically, CDK18 activated the RAS/mitogen-activated protein kinase kinase1/extracellular signal-regulated kinase pathway, thus promoting OPC differentiation. The results of the present study suggest that CDK18 is a promising cell-type specific target to treat demyelinating disease. | Yuchen Pan Zeping Jiang Dingya Sun Zhenghao Li Yingyan Pu Dan Wang Aijun Huang Cheng He Li Cao | 2019 | Neuroscience Bulletin2019，35，5： | 4 |
| 14 | Enhancement of cytotoxic T lymphocyte activity by dendritic cells loaded with Tat-protein transduction domain-fused hepatitis B virus core antigen显示文摘人的免疫不全 virus-1-Tat 蛋白质的蛋白质 transduction 领域(PTD ) 有唯一的力量渗透细胞的膜。综合 Tat-PTD 47 的顺序 57 和肝炎 B 病毒核心抗原(HBcAg ) ,我们拼接这些序列并且连接了熔化基因进 pMAL-c2x 向量。熔化蛋白质被亲密关系层析净化并且与骨头搏动了导出髓的树枝状的房间(DC ) ,和 recombinant 蛋白质的 transduction 被免疫检测荧光抗体试金。当 recombinant HBcAg 在房间的表面上被检测时,结果证明 recombinant PTD-HBcAg 能渗透细胞质进 DC。DC 表面分子的百分比 CD86 和主要 histocompatibility 建筑群 II,和 recombinant PTD-HBcAg 导致的 cytokine (IL-12p70 ) 的生产例如 CD80,比 recombinant HBcAg 或肿瘤坏死 factor-α 导致的那些显著地高。与 PTD-HBcAg 对待的 DC 导致了 T 房间区分进特定的细胞毒素的 T 淋巴细胞(CTL ) 并且提高了杀死反应的 CTL。在结论,表示并且净化的 PTD-HBcAg 熔化蛋白质能通过血浆膜渗透进房间,支持 DC 成熟,并且提高 T 房间反应高效地产生 HBcAg 特定的 CTL。 | Xiaohua Chen Yongsheng Yu Qingchun Pan Zhenghao Tang Jinchao Han Guoqing Zang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，12： | 4 |
| 15 | Over 16.7% efficiency of ternary organic photovoltaics by employing extra PC71BM as morphology regulator显示文摘Ternary organic photovoltaics(OPVs)are fabricated with PBDB-T-2 Cl:Y6(1:1.2,wt/wt)as the host system and extra PC71BM as the third component.The PBDB-T-2 Cl:Y6 based binary OPVs exhibit a power conversion efficiency(PCE)of 15.49%with a short circuit current(JSC)of 24.98 mA cm^-2,an open circuit voltage(VOC)of 0.868 V and a fill factor(FF)of 71.42%.A 16.71%PCE is obtained in the optimized ternary OPVs with PBDB-T-2 Cl:Y6:PC71BM(1:1.2:0.2,wt/wt)active layer,resulting from the synchronously improved JSC of 25.44 mA cm^-2,FF of 75.66%and the constant VOCof 0.868 V.The incorporated PC71BM may prefer to mix with Y6 to finely adjust phase separation,domain size and molecular arrangement in ternary active layers,which can be confirmed from the characterization on morphology,2 D grazing incidence small and wide-angle X-ray scattering,as well as Raman mapping.In addition,PC71BM may prefer to mix with Y6 to form efficient electron transport channels,which should be conducive to charge transport and collection in the optimized ternary OPVs.This work provides more insight into the underlying reasons of the third component on performance improvement of ternary OPVs,indicating ternary strategy should be an efficient method to optimize active layers for synchronously improving photon harvesting,exciton dissociation and charge transport,while keeping the simple cell fabrication technology. | Jinhua Gao Jian Wang Qiaoshi An Xiaoling Ma Zhenghao Hu Chunyu Xu Xiaoli Zhang Fujun Zhang | 2020 | Science China Chemistry2020，63，1： | 4 |
| 16 | Digital Design and Manufacture of Spatial Cams显示文摘In order to design and manufacture spatial cams rapidly and precisely,a CAD/CAM system is introduced for the design of 3D modeling and automatic programming in NC machining. Based on Pro/ENGINEER software used widely in CAD/CAM systems,according to the curve equation of spatial cam follower’s motion specification,the follower displacement curve is drawn quickly and accurately,then the 3D modeling of spatial cam is created using Pro/Feature module in accordance with this curve,afterwards,the quality of contour surface of spatial cam is inspected by the use of surface analysis,the result of which is fed back to the modeling design of spatial cam; after analyzing the machined theory of spatial cam,the NC machining code for it is programmed automatically according to this theory and the modeling completed in the Pro/Manufacture module. To design and manufacture spatial cams by this process can be modified circularly on the basis of the surface checking information in terms of feedback data,so the contour surfaces created have high precision,excellent kinematic characteristics and dynamic characteristics. | GE Zhenghao,XU Feng,YANG Fulian,LIANG Jinsheng (Shanxi University of Science & Technology,Xianyang 712081,China) | 2006 | 武汉理工大学学报2006，28，S1： | 3 |
| 17 | D-A-D structured selenadiazolesbenzothiadiazole-based near-infrared dye for enhanced photoacoustic imaging and photothermal cancer therapy显示文摘Near-infrared(NIR)small molecular organic dyes as photothermal agents for cancer photothermal therapy(PTT)have attracted considerable research attention.Herein,two donor-acceptor-donor(D-A-D)structured NIR dyes,BBTT and SeBTT,are rationally designed,where the only difference is one heteroatom within the acceptor unit varying from sulfur to selenium(Se).More importantly,SeBTT NPs exhibit stronger NIR absorbance and higher photothermal conversion efficiency(PTCE≈65.3%).In vivo experiments illustrate that SeBTT NPs can be utilized as a high contrast photoacoustic imaging(PAI)agent,and succeed in tumor suppression without noticeable damage to main organs under NIR photoirradiation.This study presents an effective molecular heteroatom surgery strategy to regulate the photothermal properties of NIR small molecules for enhanced PAI and PTT. | Zijin Cheng Tian Zhang Weili Wang Qing Shen Ying Hong Jinjun Shao Xiaoji Xie Zhenghao Fei Xiaochen Dong | 2021 | Chinese Chemical Letters2021，32，4： | 3 |
| 18 | Approaching 18%efficiency of ternary organic photovoltaics with wide bandgap polymer donor and well compatible Y6:Y6-1O as acceptor显示文摘A series of ternary organic photovoltaics(OPVs)are fabricated with one wide bandgap polymer D18-Cl as donor,and well compatible Y6 and Y6-1O as acceptor.The open-circuit-voltage(V_(OC))of ternary OPVs is monotonously increased along with the incorporation of Y6-1O,indicating that the alloy state should be formed between Y6 and Y6-1O due to their excellent compatibility.The energy loss can be minimized by incorporating Y6-1 O,leading to the V_(OC)improvement of ternary OPVs.By finely adjusting the Y6-1O content,a power conversion efficiency of 17.91%is achieved in the optimal ternary OPVs with 30 wt%Y6-1O in acceptors,resulting from synchronously improved short-circuit-current density(JSC)of 25.87 mA cm^(-2),fill factor(FF)of 76.92%and V_(OC)of 0.900 V in comparison with those of D18-Cl:Y6 binary OPVs.The JSC and FF improvement of ternary OPVs should be ascribed to comprehensively optimal photon harvesting,exciton dissociation and charge transport in ternary active layers.The more efficient charge separation and transport process in ternary active layers can be confirmed by the magnetophotocurrent and impedance spectroscopy experimental results,respectively.This work provides new insight into constructing highly efficient ternary OPVs with well compatible Y6 and its derivative as acceptor. | Xiaoling Ma Anping Zeng Jinhua Gao Zhenghao Hu Chunyu Xu Jae Hoon Son Sang Young Jeong Caixia Zhang Mengyang Li Kai Wang He Yan Zaifei Ma Yongsheng Wang Han Young Woo Fujun Zhang | 2021 | National Science Review2021，8，8： | 3 |
| 19 | DEM simulation of particle flow and separation in a vibrating flip-flow screen显示文摘Vibrating flip-flow screens(VFFS)with stretchable polyurethane sieve mats have been widely used in screening fine-grained materials in recent years.In this work,the discrete element method(DEM)is used to study the screening process in VFFS to explain particle flow and separation behavior at the particle scale.Unlike traditional vibrating screens,for VFFS,the amplitude response of each point on the elastic sieve mat is different everywhere.This study measures the kinematics of the elastic sieve mat under different conditions such as different stretched lengths and material loads.To establish the elastic sieve mat model in a DEM simulation,the continuous elastic sieve mat is discretized into multiple units,and the displacement signal of each unit tested is analyzed by Fourier series.The Fourier series analysis results of each unit are used as the setting parameters for motion.In this way,the movement of the elastic sieve mat is approximately simulated,and a DEM model of VFFS is produced.Through the simulation,the flow and separation of different-sized particles in VFFS are studied,and the reasonability of the simulation is verified by a pilot-scale screening experiment.The present study demonstrates the potential of the DEM method for the analysis of screening processes in VFFS. | Chi Yu Dongdong Lin Ningning Xu Xinwen Wang Kunwei Pu Zhenghao Wang Guofeng Zhao Runhui Geng Sanpeng Gong | 2023 | Particuology2023，，2： | 2 |
| 20 | Double-side fabrication process and millimeter waveresponse of intrinsic Josephson junctions显示文摘We adopted double-side fabrication process to prepare intrinsic Josephson junctions (IJJs) based on Bi2Sr2CaCu2O8+x (BSCCO) single crystals. Using crystal cleavage and double-side argon ion milling, we have successfully fabricated very uniform IJJs with the thickness of single crystal slice less than 200 nm. Using quasi-optical system, the response of the IJJs to millimeter wave radiation was studied. With applied magnetic field perpendicular to a-b plane, we have observed Shapiro steps under millimeter wave radiation, and the Josephson oscillation of each junction was phase-locking. | WU JingBo YI DongChao GU ZhengHao KANG Lin XU WeiWei CHEN Jian WU PeiHeng | 2009 | Chinese Science Bulletin2009，54，5： | 2 |
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