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| 1 | Current understanding of Th2 cell differentiation and function显示文摘Helper T cell(Th)has been identified as a critical immune cell for regulating immune response since 1980s.The type 2 helper Tcell(Th2),characterized by the production of interleukin-4(IL-4),IL-5 and IL-13,plays a critical role in immune response against helminths invading cutaneous or mucosal sites.It also has a functional role in the pathophysiology of allergic diseases such as asthma and allergic diarrhea.Currently,most studies have shed light on Th2 cell function and behavior in specific diseases,such as asthma and helminthes inflammation,but not on Th2 cell itself and its differentiation.Based on different cytokines and specific behavior in recent research,Th2 cell is also regarded as new subtypes of T cell,such as IL-9 secreting T cell(Th9)and CXCR5+T follicular helper cells.Here,we will discuss the latest view of Th2 cell towards their function and the involvement of Th2 cell in diseases. | Zhenhu Li Yuan Zhang Bing Sun | 2011 | Protein & Cell2011,2,8: | 11 |
| 2 | NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy显示文摘Oral squamous cell carcinoma(OSCC)is the most common type of oral malignancy,and metastasis accounts for the poor prognosis of OSCC.Autophagy is considered to facilitate OSCC development by mitigating various cellular stresses;nevertheless,the mechanisms of autophagy in OSCC cell proliferation and metastasis remain unknown.In our study,high-sensitivity label-free quantitative proteomics analysis revealed nuclear protein 1(NUPR1)as the most significantly upregulated protein in formalin-fixed paraffin-embedded tumour samples derived from OSCC patients with or without lymphatic metastasis. | Tengfei Fan Xiaoning Wang Sheng Zhang Ping Deng Yi Jiang Yidan Liang Sheng Jie Qing Wang Chuwen Li Guocai Tian Zhen Zhang Zhenhu Ren Bo Li Yanrong Chen Zhijing He Yan Luo Mingliang Chen Hanjiang Wu Zhengping Yu Huifeng Pi Zhou Zhou Zhiyuan Zhang | 2022 | Signal Transduction and Targeted Therapy2022,7,5: | 2 |
| 3 | Multiscale rescaled range analysis of EEG recordings in sevoflurane anesthesia显示文摘 | Zhenhu Liang Duan Li Gaoxiang Ouyang Yinghua Wang Logan J. Voss Jamie W. Sleigh Xiaoli Li | 2011 | Clinical Neurophysiology2011,,4: | 1 |
| 4 | Analysis of depth of anesthesia with Hilbert–Huang spectral entropy显示文摘 | Xiaoli Li Duan Li Zhenhu Liang Logan J. Voss Jamie W. Sleigh | 2008 | Clinical Neurophysiology2008,,11: | 1 |
| 5 | Organic-free synthesis of boehmite nanofi bers by Al2(SO4)3·18H2O with high pore volume显示文摘 | Song Jiaqing Li Zhenhu Xu Xiangyu | 2013 | Ind Eng Chem Res2013,52,23: | 1 |
| 6 | Nickel- boron alloy catalysts reduce the formation of Trans fatty acids in hydrogenated soybean oil显示文摘 | Li Tong-lin Zhang Wei-nong Roy Zhenhu Lee | 2009 | Food Chemistry2009,114,2: | 1 |
| 7 | Complexity measure of motor current signals for toolflute breakage detection in end milling显示文摘 | LI Xiaoli OUYANG Gaoxiang LIANG Zhenhu | 2008 | InternationalJournal of Machine Tools and Manufacture2008,48,3: | 1 |
| 8 | Synthesis of zinc phosphonated poly (ethylene imine) and its fire-retardant effect in low-density polyethylene显示文摘 | Zhang Yah Li Xiaonan Cao Zhenhu | 2015 | Industrial & Engineering Chemistry Research2015,54,13: | 1 |
| 9 | Multiscale Permutation Entropy Analysis of EEG Recordings during Sevoflurance Anesthesia显示文摘 | Li Duan Li Xiaoli Liang Zhenhu | 2010 | Journal of Neu- ral Engineering2010,7,4: | 1 |
| 10 | Industrial Applied and Mode-ling Research on Selective H2S Removal Using a RotatingPacked Bed显示文摘 | Qian Zhi Li Zhenhu Guo Kai | 2012 | Ind Eng Chem Res2012,51,23: | 1 |
| 11 | Recent advances for liquid metals:Synthesis,modification and bio-applications显示文摘Considering the application requirements for modern biomedicine,research into novel biomaterials with unusual functions is highly desired.As an alternative,liquid metals(LMs),a nontraditional family of metal materials,have piqued the interest of biomedical researchers and made significant advances in biomed-ical areas,owing to their shape transformability,self-healing capability,excellent electrical,and thermal conductivities.In particular,many functionalized strategies for the preparation and modification of LMs or LMs-based composites to achieve extended biomedical applications have been investigated in recent years.These findings provided inspiring while constructive reference for the fabrication and engineering of novel LMs-based composites.Herein,in this topic review,we elaborate on the recent advances of LMs-based functional materials,with particular focuses on the synthesis,modification,and bio-applications,especially in antitumor therapy,antibacterial,contrast agent for imaging,bone repair,electronic skin sen-sor,and nerve connection agent.Further on,the current challenges and future prospects of LMs-based composites are carefully discussed. | Zhenhu Guo Xiaohan Gao Jingsong Lu Wanling Xu Jielin Ye Ying Li Wensheng Xie Lingyun Zhao | 2023 | Journal of Materials Science & Technology2023,,12: | 0 |
| 12 | Additive Manufacturing of Continuous Fiber-Reinforced Polymer Composite Sandwich Structures with Multiscale Cellular Cores显示文摘The use of composite sandwich structures with cellular cores is prevalent in lightweight designs owing to their superior energy-absorbing abilities.However,current manufacturing processes,such as hot-press molding and mold pressing,require multiple steps and complex tools,thus limiting the exploration of advanced sandwich structure designs.This study reports a novel multi-material additive manufacturing(AM)process that allows the single-step production of continuous fiber-reinforced polymer composite(CFRPC)sandwich structures with multiscale cellular cores.Specifically,the integration of CFRPC-AM and in situ foam AM processes provides effective and efficient fabrication of CFRPC panels and multiscale cellular cores with intricate designs.The cellular core design spans three levels:microcellular,unit-cell,and graded structures.Sandwich structures with a diverse set of unit-cell designs,that is,rhombus,square,honeycomb,and re-entrant honeycomb,were fabricated and their flexural behaviors were studied experimentally.The results showed that the sandwich structure with a rhombus core design possessed the highest flexural stiffness,strength,and specific energy absorption.In addition,the effect of the unit-cell assembly on the flexural performance of the CFRP composite sandwich structure was examined.The proposed design and fabrication methods open new avenues for constructing novel and high-performance CFRPC structures with multiscale cellular cores that cannot be obtained using existing approaches. | Zhenhu Wang Yaohui Wang Jian He Ke Dong Guoquan Zhang Wenhao Li Yi Xiong | 2023 | Chinese Journal of Mechanical Engineering(Additive Manufacturing Frontiers)2023,2,3: | 0 |
| 13 | Zno Nanowires Network Synthesis and Its Applications on Transfer-Free UV Photodetector显示文摘Horizontally ZnO nanowires and 3D nanowires network were synthesized on dielectric silicon substrate and SiO_2 insulate substrate by catalyst-free CVD(chemical vapor deposition)method.Both the micro structure and the roughness of the substrate surface by the photoetching method and RIE ethingmethod play a significant role on the horizontally ZnO nanowires network growth when the | Wenqiang Lu Liping Xu Zhaoyao Zhan Xin Li Shuanglong Feng Zhenhu Li Shuangyi Liu | 2016 | 功能材料信息2016,13,2: | 0 |
| 14 | Synthesis of Hierarchical Nanostructures for Electrochemical Energy Storage显示文摘Electrochemical energy storage devices having high power density and energy density with robust cycle life are necessary to addressing ever-growing global energy demand.In order to realize a high-performance electrode,we designed and fabricated metal oxides-based supercapacitor electrode materials with hierarchical nanostructure.Strategies for hierarchical nanostructures are conducted to meet- | Zhenhu Li Lu Xiang Shuangyi Liu | 2016 | 功能材料信息2016,13,2: | 0 |
| 15 | Differential Expression of Neutrophilic Granule Proteins between Th1 and Th2 Cells显示文摘T 助手房间类型 1 ( Th1 )并且( Th2 ) 2 在新奇基因差别在 Th1 和 Th2 房间之间表示了的有免疫力的 regulation.Toidentify 起中央作用,CD4^+ T 房间从 DO11.10 转基因的老鼠被孤立并且在 Th1 或 Th2 conditions.Microarray 下面导致了在 Th1 和 Th2 cells.NGP 之间的 neutrophilic 小粒蛋白质( NGP )的显示出的微分表示首先与相同作为myeloid特定的小粒蛋白质被识别到 cystatin 总科。这里,我们由反向的抄写聚合酶链反应和即时聚合酶链反应分析在 Th2 房间证实了 NGP 的更大的表示。我们也证明 NGP mRNA 的表示在 Th2 下面在 5 d 文化以后有山峰表情 -- 然而并非偏导 Th1 条件。对准备的 NGPwas 的抗体,并且在有 mRNA 分析的结果的音乐会,在蛋白质印迹分析检测的 Th2 房间的 NGP 蛋白质的水平在在 HeLa 房间的 Th1 cells.GFP-NGP 熔化 proteinsoverexpressed 也比那高对细胞质局部性。这些结果建议 NGP 是把 Th2 与 Th 1 房间区分开来的一个新奇标记,也许,新奇 cytokine 由 Th2 房间藏匿。 | De’e XIE~(1,2#) Zhiduo LIU~(1#) Zhenhu LI~1 Yongyong JI~1 Jiwu CHEN~2 and Bing SUN~(1*) ~1Institute of Biochemistry and Cell Biology,Shanghai Institutes for Biological Sciences,Shanghai 200031,China ~2School of Life Science,East East China Normal University,Shanghai 200062,China | 2007 | Acta Biochimica et Biophysica Sinica2007,39,1: | 0 |
| 16 | Correction to:NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy显示文摘In the process of checking the raw data1,the authors noticed several inadvertent mistakes occurring in Fig.5a,b,c,d,f that need to be corrected after online publication of the article.During the preparation of Fig.5,the representative image showing TFE3 overexpression antagonized the NUPR1 KD-induced inhibition of OSCC cell proliferation and metastasis,were pasted and placed by mistake.The correct results should be as shown below.The authors apologize for these oversights and declare that these corrections do not affect the description,interpretation,or conclusions detailed in the original manuscript. | Tengfei Fan Xiaoning Wang Sheng Zhang Ping Deng Yi Jiang Yidan Liang Sheng Jie Qing Wang Chuwen Li Guocai Tian Zhen Zhang Zhenhu Ren Bo Li Yanrong Chen Zhijing He Yan Luo Mingliang Chen Hanjiang Wu Zhengping Yu Huifeng Pi Zhou Zhou Zhiyuan Zhang | 2022 | Signal Transduction and Targeted Therapy2022,7,10: | 0 |