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| 1 | Transferrin receptor and ferritin-H are developmentally regulated in oligodendrocyte lineage cells显示文摘Iron is an essential trophic element that is required for cell viability and differentiation, especially in oligodendrocytes, which consume relatively high rates of energy to produce myelin. Multiple iron metabolism proteins are expressed in the brain including transferrin receptor and ferritin-H. However, it is still unknown whether they are developmentally regulated in oligodendrocyte lineage cells for myelination. Here, using an in vitro cultured differentiation model of oligodendrocytes, we found that both transferrin receptor and ferritin-H are significantly upregulated during oligodendrocyte maturation, implying the essential role of iron in the development of oligodendrocytes. Additional different doses of Fe3+ in the cultured medium did not affect oligodendrocyte precursor cell maturation or ferritin-H expression but decreased the expression of the transferrin receptor. These results indicate that upregulation of both transferrin receptor and ferritin-H contributes to maturation and myelination of oligodendrocyte precursor cells. | Yunxia Li Qiang Guan Yuhui Chen Hongjie Han Wuchao Liu Zhiyu Nie | 2013 | Neural Regeneration Research2013，8，1： | 7 |
| 2 | Elastic Scattering of 7Be on Pb Target显示文摘 | Yang Yanyun Wang Jiansong Wang Qi Huang Meirong Ma Junbing Ma Peng Cao Xiguang Han Jianlong Bai Zhen Jin Shilong Hu Qiang Jin Lei Chen Jiangbo Zhang Xueying Chen Ruofu Hu Zhengguo Xu Shiwei Zhen Chuan Xu Zhiguo Xu Hushan Duan Liming Sun Zhiyu Chen Zhiqiang He Jianjun Li Songlin Lei Xiangguo Fu Fen Zhang Xueheng Yuan Xiaohua Du Chengming Yan Xinshuang Hu Jun Tang Shuwen Ye Ruiping Yang Kun Shi Fudong Zhang Wei Chen Ze Li Long Xu Xing Liu Longxiang Zhang Liyong Lin Qingyun Gou Boxing Xu Ge Zhou Xionghong Zhang Yuhu Xiao Guoqing | 2011 | IMP & HIRFL Annual Report2011，，1： | 4 |
| 3 | Cholecystectomy is associated with higher risk of recurrence after microwave ablation of hepatocellular carcinoma:a propensity score matching analysis显示文摘Objective:To explore the association between cholecystectomy and the prognostic outcomes of patients with hepatocellular carcinoma(H CC)who underwent microwave ablation(MWA).Methods:Patients with HCC(«=921)who underwent MWA were included and divided into cholecystectomy(n=114)and non-cholecystectomy groups(n=807).After propensity score matching(PSM)at a 1:2 ratio,overall survival(OS)and disease-free survival(DFS)rates were analyzed to compare prognostic outcomes between the cholecystectomy(«=114)and non-cholecystectomy groups(n=228).Univariate and multivariate Cox analyses were performed to assess potential risk factors for OS and DFS.Major complications were also compared between the groups.Results:After matching,no significant differences between groups were observed in baseline characteristics.The 1-,3-,and 5-year OS rates were 96.5%,82.1%,and 67.1%in the cholecystectomy group,and 97.4%,85.2%,and 74.4%in the non-cholecystectomy group(P=0.396);the 1-,3-,and 5-year DFS rates were 58.4%,34.5%,and 26.6%in the cholecystectomy group,and 73.6%,44.7%,and 32.2%in the non-cholecystectomy group(P=0.026),respectively.The intrahepatic distant recurrence rate in the cholecystectomy group was significantly higher than that in the non-cholecystectomy group(P=0.026),and the local tumor recurrence and extrahepatic recurrence rates did not significantly differ between the groups(P=0.609 and P=0.879).Multivariate analysis revealed that cholecystectomy(HR=1.364,95%Cl 1.023-1.819,P=0.035),number of tumors(2 vs.1:HR=2.744,95%Cl 1.925-3.912,P<0.001;3 vs.1:HR=3.411,95%Cl 2.021-5.759,P<0.001),and y-GT levels(HR=1.003,95%Cl 1.000-1.006,P<0.024)were independent risk factors for DFS.The best y-GT level cut-off value for predicting median DFS was 39.6 U/L(area under the curve=0.600,P<0.05).A positive correlation was observed between cholecystectomy and y-GT level(r=0.108,95%Cl-0.001-0.214,P=0.047).Subgroup analysis showed that the DFS rates were significantly higher in the non-cholecystectomy group than the cholecystectomy group when Y-GT>39.6 U/L(i3=0.044).The 5-,10-,15-,20-,and 25-year recurrence rates from the time of cholecystectomy were 2.63%,21.93%,42.11%,58.77%,and 65.79%,respectively.A significant positive correlation was observed between cholecystectomy and the time from cholecystectomy to recurrence(r=0.205,95%Cl 0.016-0.379,P=0.029).There were no significant differences in complications between groups(P=0.685).Conclusions:Patients with HCC who underwent cholecystectomy were more likely to develop intrahepatic distant recurrence after MWA,an outcome probably associated with increased y-GT levels.Moreover,the recurrence rates increased with time. | Hongcai Yang Yi Yang Jianping Dou Rui Cui Zhigang Cheng Zhiyu Han Fangyi Liu Xiaoling Yu Xiang Zhou Jie Yu Ping Liang | 2020 | Cancer Biology & Medicine2020，17，2： | 3 |
| 4 | Poly(ionic liquid)-crosslinked graphene oxide/carbon nanotube membranes as efficient solar steam generators显示文摘Graphene oxide(GO)is regarded as a promising candidate to construct solar absorbers for addressing freshwater crisis,but the easy delamination of GO in water poses a critical challenge for practical solar desalination.Herein,we improve the stability of GO membranes by a self-crosslinking poly(ionic liquid)(PIL)in a mild condition,which crosslinks neighbouring GO nanosheets without blemishing the hydrophilic structure of GO.By further adding carbon nanotubes(CNTs),the sandwiched GO/CNT@PIL(GCP)membrane displays a good stability in pH=1 or 13 solution even for 270 days.The molecular dynamics simulation results indicate that the generation of water nanofluidics in nanochannels of GO nanosheets remarkably reduces the water evaporation enthalpy in GCP membrane,compared to bulk water.Consequently,the GCP membrane exhibits a high evaporation rate(1.87 kg m^(-2)h^(-1))and displays stable evaporation rates for 14 h under 1 kW m^(-2)irradiation.The GCP membrane additionally works very well when using different water sources(e.g.,dye-polluted water)or even strong acidic solution(pH=1)or basic solution(pH=13).More importantly,through bundling pluralities of GCP membrane,an efficient solar desalination device is developed to produce drinkable water from seawater.The average daily drinkable water amount in sunny day is 10.1 kg m^(-2),which meets with the daily drinkable water needs of five adults.The high evaporation rate,long-time durability and good scalability make the GCP membrane an outstanding candidate for practical solar seawater desalination. | Jiangjin Han Zhiyue Dong Liang Hao Jiang Gong Qiang Zhao | 2023 | Green Energy & Environment2023，8，1： | 2 |
| 5 | Parametrization of woods-saxon potential for heavy-ion systems显示文摘Several elastic scattering angular distributions of ^(12)C from target nuclei of A ≥39 are analyzed to extract the Woods-Saxon potential parameters with the fixed imaginary potential and Coulomb radius parameters.Using the best fitted diffuseness parameters,the correlations of the real part parameters with A_1^(1/3)+ A_2^(1/3) and incident energy are revealed, and the systematic Woods-Saxon potential parameters are presented for nucleus-nucleus interaction.The proposed potential parameters can reproduce not only the elastic scattering angular distributions induced by ^(12)C,but also many elastic scattering angular distributions induced by the projectiles other than ^(12)C,thus providing important inputs for the study of nuclear reactions of heavy-ion systems. | Lin Gan ZhiHong Li HuiBin Sun DanYang Pang Bing Guo YunJu Li Jun Su ShengQuan Yan ErTao Li YouBao Wang Gang Lian ZhiYu Han XinYue Li DongHui Li TianLi Ma ChangJin Pei YangPing Shen Yi Su Sheng Zeng Yong Zhou WeiPing Liu | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，8： | 2 |
| 6 | WEAR AND SEALING CHARACTERISTICS OF ENGINE VALVE GUIDE显示文摘A novel powder metallurgy (P/M) material with high wear resistance is developed in orderto decrease the wear and lubricant-leakage of a diesel engine valve guide. The friction and wear tests ofthis material are conducted. It indicates that the wear resistance of the newly developed P/M materialhas been improved and much better than that of the formerly used alloy steel. Moreover, three differentsealing structures are designed and theoretically analyzed with respect to the characteristic of hydro-dynamic sealing. Through comparative experiments of component leakage and engine run-in for dif-ferent valve guide structures, it proves that the structure with a machined sealing groove but not in-stalled with a seal-ring cannot only reduce the specific lubricant consumption (SLC) of cylinder head,but also decrease the wear of valve stem and valve guide. | Qu Shengguan Xia Wei Han Lifa Xiao Zhiyu Chen Weiping LiYuanyuan | 2005 | Chinese Journal of Mechanical Engineering2005，18，3： | 2 |
| 7 | Effect of inverted T arrangement on AC pollution flashover characteristics of insulator strings显示文摘The arrangement of insulator strings has an effect on its pollution flashover characteristics.A new arrangement of insulator strings,inverted T-type arrangement,is proposed in this study.The electric field distribution is simulated and the pollution flashover characteristics are tested in an artificial climate chamber.The test results indicate that the inverted T-type arrangement can greatly improve the flashover voltage of polluted insulator strings,the‘7+2’inverted T-type arrangement can increase the flashover voltage of each insulator by 8.5%on average,and the‘3+3’inverted T-type arrangement can increase the flashover voltage of each insulator by 13.4%.The discharge process is different from that of the normal suspension string when the insulator string is inverted T-shaped,i.e.a local arc is produced at the low voltage end of the insulator string and develops downward along the suspension part.While as for the horizontal tension string parts,it is difficult to generate arc during discharge development. | Xingliang Jiang Xiaodong Ren Han Wang Xingbo Han Conglai Bi Zhiyu Li Ledong Hou | 2019 | High Voltage2019，4，2： | 2 |
| 8 | Nomogram based on albumin-bilirubin grade to predict outcome of the patients with hepatitis C virus-related hepatocellular carcinoma after microwave ablation显示文摘Objective:To construct a nomogram based on the albumin-bilirubin(ALBI)grade to provide prognostic value for hepatitis C virus(HCV)-related hepatocellular carcinoma(HCC)patients who underwent ultrasound-guided percutaneous microwave ablation(US-PMWA).Methods:From April 2005 to January 2018,183 treatment-naIve patients with 251 HCV-related HCCs according to the Milan criteria received US-PMWA subsequently.The overall survival(OS)and recurrence-free survival(RFS)were compared between groups classified by ALBI grade.Cox proportional hazard regression model based on risk factors for survival and recurrence was used to construct the nomogram.Results:The cumulative OS rates at 1-,3-,5-and 10-year were 97.7%,73.6%,54.5%and 34.5%,respectively.Stratified according to ALBI grade,the 1-,3-,and 5-year OS in the ALBI grade 1 group and grade 2 group were 99.2%,92.4%,77.9% and 97.7%,52.3%,38.6%,respectively,with significant statistical difference(P<0.001).No significant statistical difference was detected in the1-,3-,and 5-year RFS rates in the ALBI grade 1 group and grade 2 group(P=0.220).The major complication rate was 1.6%.Multivariate analysis results showed age,α-fetoprotein level,tumor number,platelet count,location,Child-Turcotte-Pugh(CTP)and ALBI grade were associated with OS,which generated the nomograms.Internal validation with 1000 bootstrapped sample sets had good concordance index of 0.769(95%CI 0.699-0.839)in OS.Conclusions:This nomogram based on ALBI grade was a visualization risk model,which could provide personalized prediction of long-term outcomes for HCV-related HCC patients after US-PMWA. | Chao An Xin Li Xiaoling Yu Zhigang Cheng Zhiyu Han Fangyi Liu Jie Yu Ping Liang | 2019 | Cancer Biology & Medicine2019，16，4： | 2 |
| 9 | Photocatalytic degradation of dodecyl-benzenesulfonate over TiO2-Cu2O under visible irradiation显示文摘 | Han Chenghui Li Zhiyu Shen Jianyi | 2009 | Journal of Hazardous Materials2009，168，： | 1 |
| 10 | EFFECT OF CROCETIN ON BLOOD PRESSURE RESTORATION AND SYNTHESIS OF INFLAMMATORY MEDIATORS IN HEART AFTER HEMORRHAGIC SHOCK IN ANESTHETIZED RATS显示文摘 | Junling Yan Zhiyu Qian Liang Sheng Bohua Zhao Lina Yang Hui Ji Xiaoyuan Han Rong Zhang | 2010 | Shock2010，，1： | 1 |
| 11 | Multidimensional modeling of spray atomization and air-fuel mixing in a direct-injection spark-ignition engine 显示文摘 | HAN Zhiyu LI Fan REITZ R D | 1997 | SAE Paper1997，，： | 1 |
| 12 | MWA Combined with TACE as a combined therapy for unresectable large-sized hepotocellular carcinoma显示文摘 | Cun Liu Ping Liang Fangyi Liu Yang Wang Xin Li Zhiyu Han Changchun Liu | 2011 | International Journal of Hyperthermia2011，，7： | 1 |
| 13 | A Temperature Wall Function Formulation for Variable-density Turbulent Flows with Application to Engine Convective Heat Transfer Modeling显示文摘 | HAN Zhiyu REITZ R O | 1997 | Int J Heat Mass Tran1997，40，3： | 1 |
| 14 | The value of artificial pleural effusion for percutaneous microwave ablation of liver tumour in the hepatic dome: A retrospective case-control study显示文摘 | Dezhi Zhang Ping Liang Xiaoling Yu Zhigang Cheng Zhiyu Han Jie Yu Fangyi Liu | 2013 | International Journal of Hyperthermia2013，，7： | 1 |
| 15 | Research on the SUS304 hot-rolled austenitic stainless steel strip by TMCP显示文摘To avoid intergranular corrosion and obtain microstructural homogenization,the conventional SUS304 austenitic stainless steel needs to be solution annealed after hot rolling.This study investigates the thermal-mechanical controlled process (TMCP) of SUS304 steel,especially the controlled rolling and online accelerated cooling procedures.The objective of this research is to reduce or even prevent carbide precipitation based on the description of the time-temperature-precipitation (TTP) curve.The dynamic and post-dynamic recrystallization behaviors of this steel ensured the homogenization of grains in this process due to,which was studied by the hot compression tests.The microstructure and the properties of the TMCP-produced SUS304 steel strip were compared with the conventional method of solution annealing.Based on the above results,the newly developed TMCP-produced SUS304 hot-rolled austenitic stainless steel strip has been successfully produced and it can be directly utilized in the cold rolling process without solution annealing. | HAN Jian HE Shen WANG Zhiyu JIANG Laizhu | 2009 | Baosteel Technical Research2009，3，2： | 1 |
| 16 | Circulating microRNA-21 as noninvasive predictive biomarker for response in cancer immunotherapy显示文摘 | Zhiyu Wang Jinxiang Han Yazhou Cui Kaixi Fan Xiaoyan Zhou | 2013 | Medical Hypotheses2013，，1： | 1 |
| 17 | Empirical formula for β^--decay half-lives of r-process nuclei显示文摘Experimental data ofβ--decay half-lives of nuclei with atomic number between 20 and 190 are investigated.A systematic formula has been proposed to calculateβ^--decay half-lives of neutron-rich nuclei,with a particular consideration on shell and pair effects,the decay energy Q as well as the nucleon numbers(Z,N).Although the formula has relatively few parameters,it reproduces the experimentalβ^--decay half-lives of neutron-rich nuclei very well.The predicted half-lives for the r-process relevant nuclei obtained with the current formula serve as reliable input in the r-process model calculations. | Yong Zhou ZhiHong Li YouBao Wang YongShou Chen Bing Guo Jun Su YunJu Li ShengQuan Yan XinYue Li ZhiYu Han YangPing Shen Lin Gan Sheng Zeng Gang Lian WeiPing Liu | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，8： | 1 |
| 18 | Generalized Bzier curves and surfaces based on Lupas q-analogue of Bemstein operator 显示文摘 | Han Liwen Chu Ying Qiu Zhiyu | 2014 | Journal of Computational and Applied Mathematics2014，261，： | 1 |
| 19 | Photocatalytic degradation of dodecyl-benzenesulfonate over TiO2- Cu2O under visible irradiation 显示文摘 | Han Chenghui Li Zhiyu Shen Jianyi | 2009 | J Hazard Mater2009，168，1： | 1 |
| 20 | 1,1'-diisopropyli(deneamino-5,5'-azotetrozole显示文摘 | Han Zhiyue Yao Qian Zhang Yinghao | 2015 | Journal of Thermal Analysis and Calorimetry2015，119，1： | 1 |
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