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| 1 | Targets and molecular mechanisms of triptolide in cancer therapy显示文摘Triptolide(TPL/TL) is a natural drug with novel anticancer effects. Preclinical studies indicated that TPL inhibits cell proliferation, induces cell apoptosis, inhibits tumor metastasis and enhances the effect of other therapeutic methods in various cancer cell lines. Multiple molecules and signaling pathways, such as caspases, heat-shock proteins, NF-κB, and deoxyribonucleic acid(DNA) repair-associated factors, are associated with the anti-cancer effect. TPL also improves chemoradiosensitivity in cancer therapy. Phase I trials indicate the potential clinical value of TPL use. However, further trials with larger sample sizes are needed to confirm these results. | Cuicui Meng Hongcheng Zhu Hongmei Song Zhongming Wang Guanhong Huang Defan Li Zhaoming Ma Jianhua Ma Qin Qin Xinchen Sun Jianxin Ma | 2014 | Chinese Journal of Cancer Research2014，26，5： | 16 |
| 2 | Toward an improved data stewardship and service for environmental and ecological science data in West China显示文摘Sharing of scientific data can help scientific research to flourish and facilitate more widespread use of scientific data for the benefit of society.The Environmental and Ecological Science Data Center for West China(WestDC),sponsored by the National Natural Science Foundation of China(NSFC),aims to collect,manage,integrate,and disseminate environmental and ecological data from western China.It also aims to provide a long-term data service for multidisciplinary research within NSFC’s‘‘Environment and Ecology of West China Research Plan’’(NSFC West Plan).An integrated platform has been developed by the WestDC,and this has the function of data sharing,acting as a knowledge repository.Major data sets developed by the WestDC include basic geographic data,the regionalization of global data set for China,scientific data for cold and arid regions in China,scientific data for the cryosphere in countries that neighbor China,data relating to the inland river basins in northwestern China,and data submitted by the NSFC West Plan projects.In compliance with the‘‘full and open’’data sharing policy,most data in the WestDC can be accessed online.Highlights include detailed data documentation,the integration of data with bibliographic knowledge,data publishing,and data reference. | Xin Li Zhuotong Nan Guodong Cheng Yongjian Ding Lizong Wu Liangxu Wang Jian Wang Youhua Ran Hongxing Li Xiaoduo Pan Zhongming Zhu | 2011 | International Journal of Digital Earth2011，4，4： | 11 |
| 3 | The Discovery of Diamonds in Chromitites of the Hegenshan Ophiolite,Inner Mongolia,China显示文摘Diamond,moissanite and a variety of other minerals,similar to those reported from ophiolites in Tibet and northern Russia,have recently been discovered in chromitites of the Hegenshan ophiolite of the Central Asian Orogenic Belt,north China. The chromitites are small,podiform and vein-like bodies hosted in dunite,clinopyroxene-bearing peridotite,troctolite and gabbro. All of the analysed chromite grains are relatively Al-rich,with Cr# [100Cr/(Cr+Al)] of about 47–53. Preliminary studies of mainly disseminated chromitite from ore body No. 3756 have identified more than 30 mineral species in addition to diamond and moissanite. These include oxides(mostly hematite,magnetite,rutile,anatase,cassiterite,and quartz),sulfides(pyrite,marcasite and others),silicates(magnesian olivine,enstatite,augite,diopside,uvarovite,pyrope,orthoclase,zircon,sphene,vesuvianite,chlorite and serpentine) and others(e.g.,calcite,monazite,glauberite,iowaite and a range of metallic alloys). This study demonstrates that diamond,moissanite and other exotic minerals can occur in high-Al,as well as high-Cr chromites,and significantly extends the geographic and age range of known diamond-bearing ophiolites. | HUANG Zhu YANG Jingsui Paul T.ROBINSON ZHU Yongwang XIONG Fahui LIU Zhao ZHANG Zhongming XU Wei | 2015 | Acta Geologica Sinica(English Edition)2015，89，2： | 6 |
| 4 | Incorporating the magnetic alignment of GO composites into Pebax matrix for gas separation显示文摘The mixed matrix membranes(MMMs) were developed by incorporating graphite oxide(GO) flakes functionalized with iron oxide(Fe_3O_4) into Pebax matrix. The Pebax/Fe_3O_4–GO MMMs were used to separate CO_2/CH_4 and CO_2/N_2 gas mixture. The results showed that the MMMs with magnetic alignment presented the better gas separation performance than that of random arrangement of Pebax/Fe_3O_4–GO mixed matrix membranes. The reason was that the Fe_3O_4–GO flakes arranged magnetically in the membrane played a multiple role in improving the performance of MMMs. Firstly, under the action of the magnetic field,the magnetic alignment of Fe_3O_4–GO flakes in Pebax matrix constructed the shorter transfer path for gas molecule, increasing the CO_2 permeability. Secondly, the hydroxyl groups in GO flakes and the presence of Fe_3O_4 have stronger binding force for water, improving the CO_2 solubility selectivity. Thirdly, the better interaction between the magnetic alignment of GO composites and polymer matrix, reduced the interface defects. Especially, the optimum gas separation performance was obtained at the Fe_3O_4–GO flakes content of 3 wt% in Pebax matrix at vertical arrangement with selectivity of 47 and 75 for CO_2/CH_4 and CO_2/N_2, respectively, and CO_2 permeability of 538 Barrer at 0.2 MPa and room temperature. | Weifang Zhu Yun Qin Zhongming Wang Jianshu Zhang Ruili Guo Xueqin Li | 2019 | Journal of Energy Chemistry2019，28，4： | 5 |
| 5 | Achievement of giant cryogenic refrigerant capacity in quinary rare-earths based high-entropy amorphous alloy显示文摘Magnetic refrigeration(MR)by utilizing the magnetocaloric(MC)effect is recognized as one of the most potential promising solid state environmentally friendly and high efficiency alternative method to the well-used state-of-the-art gas compression cooling technique.In this work,a systematic investigation of quinary equi-atomic rare-earths(RE)based Er_(20) Ho_(20) Gd_(20) Ni_(20) Co_(20) high-entropy(HE)amorphous alloy in terms of the microstructure,magnetic and magnetocaloric(MC)properties have been reported.The Er_(20) Ho_(20) Gd_(20) Ni_(20) Co_(20) exhibits promising glass forming ability with an undercooled liquid region of 72 K.Excellent cryogenic MC performances can be found in wide temperature from∼25 and∼75 K,close to H_(2) and N_(2) liquefaction,respectively.Apart from the largest magnetic entropy change(-S M)reaches 17.84 J/(kg K)with 0-7 T magnetic field change,corresponding refrigerant capacity(RC)attains a giant value of 1030 J/kg.The promising cryogenic MC performances together with the unique HE amorphous characterizations make the quinary Er_(20) Ho_(20) Gd_(20) Ni_(20) Co_(20) HE amorphous alloy attractive for cryogenic MR applications. | Yikun Zhang Jian Zhu Shuo Li Jiang Wang Zhongming Ren | 2022 | Journal of Materials Science & Technology2022，，7： | 4 |
| 6 | Evolution of the microstructure and solute distribution of Sn-10wt% Bi alloys during electromagnetic field-assisted directional solidification显示文摘The effects of forced flows at different velocities on microstructure and solute distribution during the directional solidification of Sn-10 wt% Bi alloys under a simultaneous imposition of a transverse static magnetic field(TSMF) and an external direct current(DC) have been investigated experimentally and numerically. The experimental results show that the solid-liquid interface will gradually become sloping with the increase of the forced flow velocity when the thermoelectric magnetic convection(TEMC)dominates the forced flow at solidification front. However, the interface will gradually become planar as the flow velocity further increases when the electromagnetic convection(EMC) dominates the forced flow. Moreover, when the flow velocity gradually increases, the primary dendrite spacing decreases from384 to 105 μm accordingly. The simulation results show that the solute distribution at the two sides of the sample can be significantly changed by the forced flow at solidification front. The rejected solute will be unidirectionally transported to one side of the sample along the TEMC(a low-velocity forced flow),thereby causing the formation of a sloping interface. However, the rejected solute will be returned back along the EMC(a higher-velocity force flow), which results in a planar interface. Furthermore, the solute content at the two sides of the sample under the forced flows at different velocities was measured. The results are in good agreement with the simulation results, which shows that the solute content difference between the two sides of the sample reaches the maximum when a 0.5 T TSMF is applied, while the solute content difference decreases to zero with a simultaneous application of a 0.5 T TSMF and a 1.6 × 10~5 A/m^2 external DC. | Zhe Shen Minghu Peng Dongsheng Zhu Tianxiang Zheng Yunbo Zhong Weili Ren Chuanjun Li Weidong Xuan Zhongming Ren | 2019 | Journal of Materials Science & Technology2019，35，4： | 4 |
| 7 | NUMERICAL SIMULATION OF ALTERNATIVE HORIZONTAL LEVITATION ELECTROMAGNETIC CONTINUOUS CASTING(Ⅱ)显示文摘NUMERICALSIMULATIONOFALTERNATIVEHORIZONTALLEVITATIONELECTROMAGNETICCONTINUOUSCASTING(Ⅱ)￥ZhuShoujun;RenZhongming;DengKang;Jian... | Zhu Shoujun Ren Zhongming Deng Kang Jiang Guochang(Shanghai Enhanced Laboratory of Ferrometallurgy,Shanghai University,Shanghai 200072) | 1996 | 中国有色金属学会会刊:英文版1996，6，4： | 4 |
| 8 | ELECTROMAGNETIC MODEL OF LEVITATION MELTING WITH COLD CRUCIBLE显示文摘ELECTROMAGNETICMODELOFLEVITATIONMELTINGWITHCOLDCRUCIBLEDengKang;ZhouYueming;RenZhongming;ZhuShoujun;WeiJihe;JiangGuochang(Sha... | Deng Kang Zhou Yueming Ren Zhongming Zhu Shoujun Wei Jihe Jiang Guochang(Shanghai Enhanced Laboratory of Ferrometallurgy,Shanghai University, Shanghai 200072) | 1996 | 中国有色金属学会会刊:英文版1996，6，2： | 3 |
| 9 | Developing institutional repositories network:Taking IR Grid at Chinese Academy of Sciences as an example显示文摘This paper introduces the current practice of building a network of institutional repositories(IRs)at Chinese Academy of Sciences(CAS),which is named CAS IR Grid.National Science Library(NSL)of CAS plays a leading role in the construction,promotion and implementation of CAS IR Grid.It aims to promote each institute of CAS to build IR of its own,and finally form the IR network of CAS institutes.NSL’s experience is introduced in coordinating and supporting institutes’building of their respective IRs and promoting IR services by adopting collaborative and progressive development strategies.Achievements made during the development of CAS IR Grid are described and challenges for its future development are discussed.The authors aim to provide best practices for developing a network of institutional repositories in research institute settings,which can serve as a practical reference to other institutions engaged in the similar task. | Zhongming ZHU Dongrong ZHANG Lin LI Jianxia MA Xiwen LIU | 2011 | Chinese Journal of Library and Information Science2011，，Z1： | 2 |
| 10 | Analysis of strand breakage caused by conductor vibration in transmission lines显示文摘I. Introduction A 31.2 km 110 kV transmission line is designed to operateunder 35 kV with conductor model AC-185 (aluminium strand-- 28 x 2.87 mm^2, steel core -- 7 x 2.50 mm^2) at average oper-ating stress of 24. 2%, and overhead ground wire model C-50(steel strand -- 7 x 2.97 mm^2) at average operating stress of20.6%. The whole line has 130 pole-towers, most of which are ofprestressed concrete double-pole structure, as shown in Fig.1. | Zhu Zhongming Suzhou Thermal Power Research Institute Shen Hongming | 1992 | Electricity1992，，2： | 2 |
| 11 | In situ Assemblies of Bacteria and Nutrient Dynamics in Response to an Ecosystem Engineer,Marine Clam Scapharca subcrenata,in the Sediment of an Aquaculture Bioremediation System显示文摘The relationships between nutrient dynamics,microbial community,and macrofauna are important in bioremediation systems.In this study,we examined the effects of marine clam Scapharca subcrenata sedimentary activities on the microbial assemblages,benthic nutrient chemistry,and its subsequent remediation impacts on organic effluent in the sediment of an aquaculture wastewater bioremediation system.The results showed that microbial community composition differed significantly in the clam area(ANOSIM,R=0.707,P=0.037).Pyrosequencing of bacterial 16S rRNA gene revealed a total of 48 unique phyla,79 classes,107 orders,197 families,and 321 genera amongst all samples.The most dominant bacterial assemblages were Proteobacteria,Bacteroidetes,Acidobacteria,Firmicutes,Verrucomicrobia,and Actinobacteria,with Bacteroidetes and Firmicutes significantly higher in all treatment samples than control(P<0.001).All dominant phyla in the list were shared across all samples and accounted for 89%(control)and 97%(treatment)of the total 16S rRNA.The nutrient flux rates from the sediments into the water(treatment group)were 51%(ammonium),88%(nitrate),77%(nitrite)and 45%(phosphate)higher,relative to the control implying increased mineralization,degradability,and mobility of the benthic nutrients.Similarly,significantly increased oxygen consumption rates were evident in the clam area signifying improved oxygen distribution within the sediment.The organic effluent contents associated with total-organic matter,carbon,nitrogen,and,phosphate were lower among the clam treatments relative to the control.Our results describe the potential roles and mechanisms contributed by marine bivalve S.subcrenata on benthic-bacterial-community assembly,nutrient balance,and effluent reduction in the sediments of aquaculture wastewaters bioremediation system. | NICHOLAUS Regan LUKWAMBE Betina YANG Wen ZHU Jinyong ZHENG Zhongming | 2020 | Journal of Ocean University of China2020，19，6： | 2 |
| 12 | On Hilbert Coefficients of Filtrations显示文摘让 F 是关于 Cohen 麦考莱模块 M 的 Hilbert 过滤。什么时候 G (F, M ) ;F K (F, M ) 有几乎最大的深度, Hilbert 系数 g i (F, M ) 被计算。在一般盒子中,为 g 的上面的界限 2 (F, M ) 也被给。 | Yan GU Guangjun ZHU Zhongming TANG | 2007 | Chinese Annals of Mathematics,Series B2007，28，5： | 1 |
| 13 | An Attempt of Data Exchange Between the Institutional Repository and the Information Environment for the Management of Scientific Research -ARP显示文摘 | Ma Jianxia Wang Yuanming Zhu Zhongming | 2009 | Library Collection Acquisitions and Technical Services2009，2009，1： | 1 |
| 14 | An Attempt of Data Exchange Between the Institutional Repository and the Information Environment for the Management of Scientific Research --ARP显示文摘 | Ma Jianxia Wang Yuanming Zhu Zhongming | 2009 | Library Collections Acquisitions and Technical Services2009，2009，1： | 1 |
| 15 | Micropropa- gation and pharmacological analysis of a medicinal herb Sarcandra glabra 显示文摘 | Shuying Zhu Tao Liu Zhongming Fang | 2011 | Medicinal and Aromatic Plant Science and Biotechnology2011，5，1： | 1 |
| 16 | The Discovery of Diamonds in Chromitite of the Hegenshan Ophiolite, Inner Mongolia显示文摘Diamonds,moissanite and a variety of other minerals,similar to those reported from ophiolites in Tibet and northern Russia(Yang et al.,2011),have recently been discovered in chromitites of the Hegenshan ophiolite of the Central Asian Orogenic Belt.The Hegenshan ophiolite is located in Xilinhaote,Inner Mongolia,180 km north | HUANG Zhu YANG Jingsui ZHU Yongwang XIONG Fahui LIU Zhao ZHANG Zhongming XU Wei | 2015 | Acta Geologica Sinica(English Edition)2015，89，A02： | 1 |
| 17 | Metabolic changes of starch and lipid triggered by nitrogen starvation in the microalga Chlorella zofingiensis 显示文摘 | Zhu Shunni Huang Wei Xu Jin Wang Zhongming Yuan Zhenhong | 2014 | Bioresource Technology2014，152，： | 1 |
| 18 | Suppression of LjBAK1-mediated immunity by SymRK promotes rhizobial infection in Lotus japonicus.显示文摘An important question in biology is how organisms can associate with different microbes that pose no threat (commensals), pose a severe threat (pathogens) and those that are beneficial (symbionts). The root nodule symbiosis serves as important model system to address such questions in the context of plant-microbe interactions. It is now generally accepted that rhizobia have the abilities to actively suppress host immune responses during the infection process, analogous to the way in which plant pathogens can evade immune recognition. However, much remains to be elucidated with regard to the mechanisms by which the host recognizes the rhizobia as pathogens and how, subsequently, these pathways are suppressed to allow establishment of the nitrogen fixing symbiosis. In this study, we found that SymRK (Symbiosis Receptor-like Kinase) is required for rhizobial suppression of plant innate immunity in Lotus japonicus. SymRK associates with LjBAK1 (BRASSINOSTEROID INSENSITIVE 1-Associated receptor Kinase 1), a well characterized, positive regulator of plant innate immunity, and directly inhibits LjBAK1 kinase activity. Rhizobial inoculation enhances the association between SymRK and LjBAK1 in planta. LjBAK1 is required to regulate plant innate immunity and plays a negative role in mediating rhizobial infection in L. japonicus. The data indicate that the protein complex of SymRK-LjBAK1 serves as an intersection point between rhizobial symbiotic signaling pathways and innate immunity pathways, which provides an evidence that rhizobia might actively suppress the host's ability to mount a defense response in the legume-rhizobium symbiosis. | Yong Feng Ping Wu Chao Liu Liwei Peng Tao Wang Chao Wang Qian Tan Bixuan Li Yajuan Ou Hui Zhu Songli Yuan Renliang Huang Gary Stacey Zhongming Zhang Yangrong Cao | 2021 | Molecular Plant2021，14，11： | 0 |
| 19 | NMR-based metabolomic responses of freshwater gastropod Bellamya aeruginosa to MC-producing and non MC-producing Microcystis aeruginosa显示文摘Molluscan metabolomic analysis is essential for the understanding of the regulatory mechanism of aquatic invertebrate in response to hepatotoxic microcystins(MCs)stress.To understand the system responses of the gastropod to MC exposure,metabolomic alterations caused by two strains(MC-producing and non MC-producing)of Microcystis aeruginosa were characterized indiff erent biological matrices(hepatopancreas and muscle)of Bellamya aeruginosa(Gastropoda)using 1 H nuclear magnetic resonance(NMR)spectroscopy combined with MCs detections after exposure for 1,7,and 14 d.Although ELISA analysis showed that no MCs was detected in both tissues after non MC-producing M.aeruginosa exposure,MCs concentrations were increasing in the hepatopancreas(from 1.29±0.48μg/g to 3.17±0.11μg/g)and foot muscle(from 0.07±0.02μg/g to 0.21±0.08μg/g)after 14-d exposure of MC-producing M.aeruginosa.Meanwhile,we observed that MC induced signifi cant increase in creatine,a variety of amino acids(leucine,isoleucine,valine,threonine,alanine,methionine,glutamate,aspartate,and lysine),carboxylic acids(lactate,acetate,and D-3-hydroxybutyrate),and choline and its derivatives(phosphocholine and glycerophosphocholine)but decreased the energy substance(lipids,glucose,and glycogen)in the hepatopancreas.However,no signifi cant metabolite diff erences were observed in the muscle between MC-producing and non MC-producing cyanobacteria treated groups.These results suggest that MC exposure may cause hepatic energy expenditure accompanied with various metabolic disorders that involve lipid metabolism,protein catabolism,osmoregulation,glycolysis,glycogenolysis,and tricarboxylic acid(TCA)cycle.Moreover,metabolic perturbation was aggravated as the level of accumulated MCs raised over time in the MC-producing cyanobacteria treatment.These fi ndings indicated that MCs accumulation might lead to oxidative-stress-mediated damage of mitochondria functions. | Wen YANG Yangfang YE Kaihong LU Zhongming ZHENG Jinyong ZHU | 2022 | Journal of Oceanology and Limnology2022，40，1： | 0 |
| 20 | Conformally Mapped Multifunctional Acoustic Metamaterial Lens for Spectral Sound Guiding and Talbot Effect显示文摘We demonstrate a conformally mapped multifunctional acoustic metamaterial Mikaelian lens.Mikaelian lens is a gradient medium with a hyperbolic secant refractive index profile that can realize functions like beam self-focusing.Unlike the conventional design approaches,with a conformal transformation method,only isotropic material parameters with gradient refractive index profiles are required for the construction of such lens.To realize desired gradient index distribution,we carefully design a new type of crosschannel-shaped acoustic metamaterial,whose refractive index can be effectively modulated by simply changing the slit opening size.The distinct capabilities of the metamaterial Mikaelian lens in manipulating acoustic waves are experimentally verified with the fabricated sample.Simultaneous sound guiding and Talbot effects,which normally require respective geometrical and wave acoustic approximations,are observed in simulations and experiments.Furthermore,those effects of shaping acoustic wave propagations were validated within a relatively wide frequency range.Our study reveals how the conformal transformation method can help to bridge the ray acoustics with wave acoustics.It offers opportunities to the development of novel multifunctional acoustic devices for various applications,such as sound and particle manipulations. | He Gao Xinsheng Fang Zhongming Gu Tuo Liu Shanjun Liang Yong Li Jie Zhu | 2019 | Research2019，，1： | 0 |
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