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2564篇 您的检索式:作者名="Zhou L F"
    题名 作者 年代 出处 被引量
12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2Leber's hereditary optic neuropathy is associated with the mitochondrial ND4 G11696A mutation in five Chinese families显示文摘Zhou XT Wei QP Yang L Tong Y Zhao FX Lu CJ Qian YP Sun YH Lu F Qu J Guan MX 2006中国生物学文摘2006,20,4:18
3Rapid nongenomic inhibitory effects of glucocorticoids on phagocytosis and superoxide anion production by macrophages显示文摘Long F Wang YX Liu L Zhou J Cui RY Jiang CL 2005第二军医大学学报2005,26,10:14
4Polymorphisms of MTHFD,plasma homocysteine levels, and risk of gastric cancer in ahigh-risk Chinese population显示文摘Purpose:Accumulative evidence suggests that folate has a protective effect on gastric cancer. The methylenetetrahyd-rofolate dlehydrogenase(MTHFD) plays an important role in folate and homocysteine metabolisms, and polymorphisms of MTHFD may result in disturbance of the folate-mediated homocysteine pathway. The aim of this study is to test the hypothesis that genetic variants of MTHFD and plasma homocysteine levels are associated with risk of gastric cancer and modulated by genotypes of methylenetetrahydrofolate reductase(MTHFR). Experimental Design: We genotyped G1958A and T401C in MTHFD and C677T in MTHFR and detected total plasma homocysteine(tHcy) levels in a case-control study of 589 gastric cancer cases and 635 cancer-free controls in a high-risk Chinese population. Results:The variant genotypes of MTHFD 1958AA and 401CC were associated with a significantly increased risk of gastric canceradjusted odds ratio(OR), 2.05; 95% confidence interval(95% CI),1.34-3.13 for 1958AA; adjusted OR,1.43; 95% CI,1.14-1.80 for 401CC compared with 1958GG/GA and 401TT/TC genotypes, respectively. Both of the effects were more evident in the subjects carrying MTHFR 677CT/TT genotypes. The average tHcy level was significantly higher in gastric cancer cases than in controls(P < 0.01), and the upper quartile of tHcy (> 13.6 mu mol/L) was associated with an 82% significantly increased risk of gastric cancer, compared with the lowest quartile of tHcy(<= 8.0 pmol/L;adjusted OR,1.82; 95% CI,1.20-2.75). Conclusions:The strong associations between MTHFD variants and the plasma tHcy levels and gastric cancer risk suggest, for the first time, a possible gene-environment interaction between genetic variants of folate-metabolizing genes and high tHcy levels in gastric carcinogenesis.Wang, L. N Ke, Q Chen, W. S Wang, J. M Tan, Y. F Zhou, Y Hua, Z. L Ding, W. L Niu, J. Y Shen, J Zhang, Z. F Wang, X. R Xu, Y. H Shen, H. B Yi Xing 2007南京医科大学学报(自然科学版)2007,27,7:10
5柑桔黄龙病的鉴定和柯赫氏定理(英文)显示文摘黄龙(梢)病被认为是世界柑橘生产上的毁灭性病害已超过一个世纪,但该病害的病原学至今还没有清晰地建立起来。根据16S rRNA基因序列分析,一组被称为'Candidatus Liberibacter species'的难培养细菌被认为与黄龙病相关。然而,要确定'Ca.Liberibacter spp.'是黄龙病病原的柯赫氏定理并没有真正完成。令我们担忧的是,近年来有些文献频频指出'Ca.Liberibacter spp.'是黄龙病的病原,其实该细菌与柑橘寄主的直接病理反应还没有完全确定。我们建议,在黄龙病病原学清楚之前,文献报道在这方面需要有准确的阐述。Chen J Deng X Civerolo E L Lee R F Jones J B Zhou C Hartung J S Manjunath K L Brlansky R H 2011植物病理学报2011,41,2:10
6油炸食品与心血管病风险和全因死亡率的关系:观察性研究的荟萃分析显示文摘研究者进行了一项荟萃分析,包括剂量反应分析,以定量确定油炸食品摄入与普通成年人群心血管病风险和全因死亡率之间的关系。方法:研究者在PubMed、EMBASE和Web of Science上检索2020年4月11日之前的所有文章。应用随机效应模型估计总的相对危险度(relative risks,RR)和95%CI。结果:与最低油炸食品摄入量相比,最高摄入量者主要心血管事件的总RR(95%CI)=1.28(1.15~1.43),n=17,I^(2)=82.0%,其中前瞻性研究:1.24(1.12~1.38),n=13,I^(2)=75.7%.刘青(译) 练桂丽(审校) Qin P Zhang M Han M Liu D Luo X Xu L Zeng Y Chen Q Wang T Chen X Zhou Q Li Q Qie R Wu X Li Y Zhang Y Wu Y Hu D Hu F 2021中华高血压杂志2021,29,2:3
7Assay of serum arylesterase activity by fitting reaction curve with an integrated rate equation显示文摘Liao F Liu W L Zhou Q X 2001Clin Chim Acta2001,314,12:2
8Combinatorial modification of multiple lignin traits in trees through multigene cotransformation 显示文摘Li L Zhou Y Cheng X F 2003Plant Biology2003,100,8:1
9High-temperature oxidation of Fe-Cr alloys in wet oxygen显示文摘Shen J N Zhou L J Li T F 1997Oxidation of Metals1997,48,:1
10Dissipation of oxytetracycline in soils under different redox conditions显示文摘YANG J F YING G G ZHOU L J 2009Environl Poll2009,157,10:1
11Origin and technic significance of a Mesozoic multi-layer over-thrust system within the Yangtze Block (South china)显示文摘Yan D P Zhou M F Song H L 2003Tectonophysics2003,361,:1
12Simulation of swirling combustion and NO formation using a USM turbulence-chemistry model显示文摘Zhou L Wang F Zhang J 2003Fuel2003,82,13:1
13Electrodeposition of metallic nanowire thin films using, mesoporous silica templates显示文摘Wano D H Zhou W L McCaughv B F 2003Adv Mater2003,15,2:1
14Comprehensive understanding on the formation of highly ordered mesoporous tungsten oxides by X-ray diffraction and Raman spectroscopy显示文摘Zhou L Ren Q J Zhou X F 2008Microporous and MesoporousMaterials2008,109,13:1
15Research on environmental-friendly anodizing process for magnesium alloys显示文摘LUO S L DAI L ZHOU H H CHAI L Y KUANG Y F 2005Journal of Hunan University (Natural Sciences)2005,32,3:1
16Electrokinetic remediation of a Cu contaminated red soil by conditioning catholyte pH with different enhancing chemical reagents显示文摘Zhou D M Deng C F Cang L 2005Chemosphere2005,56,33:1
17Electrokinetic remediation of a Cu contaminated red soil by conditioning catholyte pH with different enhancing chemical reagents显示文摘Zhou D M Deng C F Cang L 2004Chemosphere2004,56,:1
18Ensemble Hydrological Pre- diction Based Real Time optimization of a Multi objective Res- ervoir during Flood Season in a Semiarid Basin with Global Numerical Weather Predictions 显示文摘Wang F Wang L Zhou H 2012Water Resources Re- search2012,48,7:1
19Complete nucleotide sequence of plasmid pST-Ⅲ from Lactobacillus plantarum ST-Ⅲ显示文摘Chen C Ai L Zhou F 0,,03:1
202013, Antigenic and genetic characterization of a European avian-like H1N1 swine influenza virus from a boy in China in 2011显示文摘Qi x Cui L Jiao Y Pan Y Li X Zu R Huo X Wu B Tang F Song Y Zhou M Wang H Cardona C J Xing Z 2013Archives of Virology2013,158,1:1
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